Rapid intra-adrenal feedback regulation of glucocorticoid synthesis

Journal of the Royal Society Interface

Volumn 12, Issue 102, 2015, Pages

  Walker, J J ^a,b   Spiga, F ^b   Gupta, R ^a   Zhao, Z ^b   Lightman, S L ^b   Terry, J R ^a,b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Adrenal gland; Glucocorticoids; Hypothalamic pituitary adrenal axis; Mathematical modelling; Stress response

Indexed keywords

MATHEMATICAL MODELS; PHYSIOLOGY; TIME DELAY;

ADRENAL GLAND; FEEDBACK MECHANISMS; FEEDBACK REGULATION; GLUCOCORTICOIDS; HYPOTHALAMIC-PITUITARY-ADRENAL AXIS; NEUROENDOCRINE SYSTEMS; SIGNALLING PATHWAYS; STRESS RESPONSE;

HORMONES;

CORTICOTROPIN; CORTICOTROPIN RECEPTOR; GLUCOCORTICOID; MELANOCORTIN 2 RECEPTOR;

ADRENAL GLAND; ADULT; ANIMAL EXPERIMENT; ARTICLE; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; FEEDBACK SYSTEM; MALE; NONHUMAN; RAT; SYNTHESIS; SYSTEMS BIOLOGY; ULTRADIAN RHYTHM; ANIMAL; BIOLOGICAL MODEL; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; FEEDBACK, PHYSIOLOGICAL; GLUCOCORTICOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MODELS, BIOLOGICAL; PITUITARY-ADRENAL SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MELANOCORTIN, TYPE 2; RECEPTORS, CORTICOTROPIN; SIGNAL TRANSDUCTION;

EID: 84964313676     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0875     Document Type: Article

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