Genetic variants of ADAM17 are implicated in the pathological process of Kawasaki disease and secondary coronary artery lesions via the TGF-β/SMAD3 signaling pathway

European Journal of Pediatrics

Volumn 175, Issue 5, 2016, Pages 705-713

  Peng, Qian ^a,b   Deng, Yan ^b   Yang, Xiling ^c   Leng, Xiangyou ^c   Yang, Yuan ^c   Liu, Hanmin ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

ADAM17; Coronary artery lesions; Kawasaki disease; SMAD3; TGF signaling pathway

Indexed keywords

SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; DNA; SMAD3 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ARTICLE; CHILD; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE; GENETIC VARIABILITY; HAN CHINESE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; CLINICAL TRIAL; COMPLICATION; CORONARY BLOOD VESSEL; DIAGNOSTIC IMAGING; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; INFANT; METABOLISM; MULTICENTER STUDY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADAM17 PROTEIN; CHILD, PRESCHOOL; CORONARY ARTERY DISEASE; CORONARY VESSELS; DNA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INFANT; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84964307771     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-016-2696-8     Document Type: Article

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