Postoperative apathy can neutralise benefits in quality of life after subthalamic stimulation for Parkinson's disease

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 87, Issue 3, 2016, Pages 311-318

  Martinez Fernandez, Raul ^a,b,c   Pelissier, Pierre ^a,b   Quesada, Jean Louis ^d   Klinger, Hélène ^e,f,g   Lhommée, Eugénie ^a,b   Schmitt, Emmanuelle ^a,b   Fraix, Valerie ^a,b   Chabardes, Stephan ^a,b,d   Mertens, Patrick ^e,f   Castrioto, Anna ^a,b   Kistner, Andrea ^a,b   Broussolle, Emmanuel ^e,f,g   Pollak, Pierre ^a,b,h   Thobois, Stéphane ^e,f,g   Krack, Paul ^a,b  

^a UNIV GRENOBLE ALPES   (France)

^b GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^c UNIVERSIDAD SAN PABLO CEU   (Spain)

^d GRENOBLE UNIVERSITY HOSPITAL   (France)

^e HÔPITAL NEUROLOGIQUE   (France)

^f UNIVERSITÉ LYON 1   (France)

^g INSTITUT DES SCIENCES COGNITIVES   (France)

^h GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA;

ADULT; ANXIETY; APATHY; ARTICLE; BRAIN DEPTH STIMULATION; COGNITION; COHORT ANALYSIS; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEPRESSION; DRUG DOSE REDUCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; OUTCOME ASSESSMENT; PARKINSON DISEASE; PARKINSON DISEASE QUESTIONNAIRE 39; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RATING SCALE; RETROSPECTIVE STUDY; SCORING SYSTEM; STARKSTEIN SCALE; SUBTHALAMIC NUCLEUS DEEP BRAIN STIMULATION; THERAPY EFFECT; UNIFIED PARKINSON DISEASE RATING SCALE; ADVERSE EFFECTS; CASE CONTROL STUDY; MIDDLE AGED; PHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; SUBTHALAMIC NUCLEUS; TREATMENT OUTCOME;

ACTIVITIES OF DAILY LIVING; ANXIETY; APATHY; CASE-CONTROL STUDIES; DEEP BRAIN STIMULATION; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; POSTOPERATIVE COMPLICATIONS; PSYCHIATRIC STATUS RATING SCALES; QUALITY OF LIFE; RETROSPECTIVE STUDIES; SUBTHALAMIC NUCLEUS; TREATMENT OUTCOME;

EID: 84964301687     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2014-310189     Document Type: Article

References (43)

1. Limousin P, Krack P, Pollak P, et al. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 1998;339:1105-11.
2. Krack P, Batir A, Van Blercom N, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003;349:1925-34.
3. Deuschl G, Schade-Brittinger C, Krack P, et al. A randomized trial of deep-brain stimulation for Parkinson's disease. N Engl J Med 2006;355:896-908.
4. Schuepbach WM, Rau J, Knudsen K, et al. Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med 2013;368:610-22.
5. Weaver FM, Follett K, Stern M, et al. Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA 2009;301:63-73.
6. Just H, Ostergaard K. Health-related quality of life in patients with advanced Parkinson's disease treated with deep brain stimulation of the subthalamic nuclei. Mov Disord 2002;17:539-45.
7. Lagrange E, Krack P, Moro E, et al. Bilateral subthalamic nucleus stimulation improves health-related quality of life in PD. Neurology 2002;59:1976-8.
8. Martinez-Martin P, Valldeoriola F, Tolosa E, et al. Bilateral subthalamic nucleus stimulation and quality of life in advanced Parkinson's disease. Mov Disord 2002;17:372-7.
9. Troster AI, Fields JA, Wilkinson S, et al. Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatology. Stereotact Funct Neurosurg 2003;80:43-7.
10. Gronchi-Perrin A, Viollier S, Ghika J, et al. Does subthalamic nucleus deep brain stimulation really improve quality of life in Parkinson's disease? Mov Disord 2006;21:1465-8.
11. Witt K, Daniels C, Reiff J, et al. Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study. Lancet Neurol 2008;7:605-14.
12. Maier F, Lewis CJ, Horstkoetter N, et al. Patients' expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach. J Neurol Neurosurg Psychiatry 2013;84:1273-81.
13. Witt K, Daniels C, Krack P, et al. Negative impact of borderline global cognitive scores on quality of life after subthalamic nucleus stimulation in Parkinson's disease. J Neurol Sci 2011;310:261-6.
14. Agid Y, Schupbach M, Gargiulo M, et al. Neurosurgery in Parkinson's disease: the doctor is happy, the patient less so? J Neural Transm Suppl 2006;70:409-14.
15. Meyers AR, Gage H, Hendricks A. Health-related quality of life in neurology. Arch Neurol 2000;57:1224-7.
16. Martinez-Martin P, Rodriguez-Blazquez C, Kurtis MM, et al. The impact of non-motor symptoms on health-related quality of life of patients with Parkinson's disease. Mov Disord 2011;26:399-406.
17. Weintraub D, Moberg PJ, Duda JE, et al. Effect of psychiatric and other nonmotor symptoms on disability in Parkinson's disease. J Am Geriatr Soc 2004;52:784-8.
18. Schrag A. Quality of life and depression in Parkinson's disease. J Neurol Sci 2006;248:151-7.
19. Barone P, Antonini A, Colosimo C, et al. The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease. Mov Disord 2009;24:1641-9.
20. Starkstein SE, Mayberg HS, Preziosi TJ, et al. Reliability, validity, and clinical correlates of apathy in Parkinson's disease. J Neuropsychiatry Clin Neurosci 1992;4:134-9.
21. Pagonabarraga J, Kulisevsky J, Strafella A, et al. Apathy in Parkinson's disease: a model to study motivated behaviours. Lancet Neurol 2015 Apr 13. In press.
22. Castrioto A, Lhommee E, Moro E, et al. Mood and behavioural effects of subthalamic stimulation in Parkinson's disease. Lancet Neurol 2014;13:287-305.
23. Campbell MC, Black KJ, Weaver PM, et al. Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease. J Neuropsychiatry Clin Neurosci 2012;24:28-36.
24. Funkiewiez A, Ardouin C, Caputo E, et al. Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004;75:834-9.
25. Drapier D, Drapier S, Sauleau P, et al. Does subthalamic nucleus stimulation induce apathy in Parkinson's disease? J Neurol 2006;253:1083-91.
26. Le Jeune F, Drapier D, Bourguignon A, et al. Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study. Neurology 2009;73:1746-51.
27. Kirsch-Darrow L, Zahodne LB, Marsiske M, et al. The trajectory of apathy after deep brain stimulation: from pre-surgery to 6 months post-surgery in Parkinson's disease. Parkinsonism Relat Disord 2011;17:182-8.
28. Funkiewiez A, Ardouin C, Cools R, et al. Effects of levodopa and subthalamic nucleus stimulation on cognitive and affective functioning in Parkinson's disease. Mov Disord 2006;21:1656-62.
29. Drapier D, Peron J, Leray E, et al. Emotion recognition impairment and apathy after subthalamic nucleus stimulation in Parkinson's disease have separate neural substrates. Neuropsychologia 2008;46:2796-801.
30. Porat O, Cohen OS, Schwartz R, et al. Association of preoperative symptom profile with psychiatric symptoms following subthalamic nucleus stimulation in patients with Parkinson's disease. J Neuropsychiatry Clin Neurosci 2009;21:398-405.
31. Thobois S, Ardouin C, Lhommee E, et al. Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation. Brain 2010;133(Pt 4):1111-27.
32. Lhommee E, Klinger H, Thobois S, et al. Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. Brain 2012; 135(Pt 5):1463-77.
33. Pollak P. Deep brain stimulation for Parkinson's disease - patient selection. Handb Clin Neurol 2013;116:97-105.
34. Peto V, Jenkinson C, Fitzpatrick R, et al. The development and validation of a short measure of functioning and well being for individuals with Parkinson's disease. Qual Life Res 1995;4:241-8.
35. Czernecki V, Schupbach M, Yaici S, et al. Apathy following subthalamic stimulation in Parkinson disease: a dopamine responsive symptom. Mov Disord 2008;23:964-9.
36. Thobois S, Lhommee E, Klinger H, et al. Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil. Brain 2013;136(Pt 5):1568-77.
37. Gervais-Bernard H, Xie-Brustolin J, Mertens P, et al. Bilateral subthalamic nucleus stimulation in advanced Parkinson's disease: five year follow-up. J Neurol 2009;256:225-33.
38. Castrioto A, Kistner A, Klinger H, et al. Psychostimulant effect of levodopa: reversing sensitisation is possible. J Neurol Neurosurg Psychiatry 2013;84:18-22.
39. Rodriguez-Oroz MC, Moro E, Krack P. Long-term outcomes of surgical therapies for Parkinson's disease. Mov Disord 2012;27:1718-28.
40. Brefel-Courbon C, Payoux P, Thalamas C, et al. Effect of levodopa on pain threshold in Parkinson's disease: a clinical and positron emission tomography study. Mov Disord 2005;20:1557-63.
41. Saint-Cyr JA, Trepanier LL, Kumar R, et al. Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease. Brain 2000;123(Pt 10):2091-108.
42. Juri C, Rodriguez-Oroz M, Obeso JA. The pathophysiological basis of sensory disturbances in Parkinson's disease. J Neurol Sci 2010;289:60-5.
43. Pellaprat J, Ory-Magne F, Canivet C, et al. Deep brain stimulation of the subthalamic nucleus improves pain in Parkinson's disease. Parkinsonism Relat Disord 2014;20:662-4.