Two new protein tyrosine phosphatase 1B inhibitors, hyattellactones A and B, from the Indonesian marine sponge Hyattella sp.

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 4, 2015, Pages 904-907

  Abdjul, Delfly B ^a   Yamazaki, Hiroyuki ^a   Takahashi, Ohgi ^a   Kirikoshi, Ryota ^a   Mangindaan, Remy E P ^b   Namikoshi, Michio ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b SAM RATULANGI UNIVERSITY   (Indonesia)

Author keywords

Hyattella sp.; Hyattellactone; Marine sponge; Phyllofolactone; PTP1B inhibitor; Scalarane sesterterpene

Indexed keywords

HYATTELLACTONE A; HYATTELLACTONE B; OLEANOLIC ACID; PHYLLOFOLACTONE F; PHYLLOFOLACTONE G; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; SESTERTERPENE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INHIBITION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HYATTELLA; IC50; INDONESIAN; INFRARED SPECTROSCOPY; MONTE CARLO METHOD; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; SPONGE (PORIFERA); STEREOCHEMISTRY;

HYATTELLA;

EID: 84964301292     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.12.058     Document Type: Article

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