Fibrillin-1 impairment enhances blood-brain barrier permeability and xanthoma formation in brains of apolipoprotein E-deficient mice

Neuroscience

Volumn 295, Issue , 2015, Pages 11-22

  Van der Donckt, C ^a   Roth, L ^a   Vanhoutte, G ^a   Blockx, I ^a   Bink, D I ^b   Ritz, K ^b   Pintelon, I ^a   Timmermans, J P ^a   Bauters, D ^c   Martinet, W ^a   Daemen, M J ^b   Verhoye, M ^a   De Meyer, G R Y ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Blood brain barrier; Choroid plexus; Fibrillin 1; Xanthomas

Indexed keywords

2-(2,6-DICHLORO-4-((3-FURAN-2-YLACRYLOYLAMINO)METHYL)BENZOYLAMINO)-3-((THIAZOLIDINE-4-CARBONYL)AMINO)PROPIONIC ACID; ACRYLAMIDE DERIVATIVE; ACTIN BINDING PROTEIN; APOLIPOPROTEIN E; BETA ALANINE; CLAUDIN 5; CYTOKINE; FIBRILLIN; FIBRILLIN 1; GADOLINIUM; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; NERVE PROTEIN; OCCLUDIN; PHARMACOKINETICS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN; BRAIN DISEASE; BRAIN VENTRICLE; CHOROID PLEXUS; CONTROLLED STUDY; DEFICIENCY; DISEASE MODEL; FEMALE; GENETICS; MALE; METABOLISM; MOUSE; NEOCORTEX; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN DIET; XANTHOMA; XANTHOMATOSIS;

ACRYLAMIDES; ANALOGS AND DERIVATIVES; ANIMALS; APOLIPOPROTEINS E; BETA-ALANINE; BLOOD-BRAIN BARRIER; BRAIN; BRAIN DISEASES; CYTOKINES; DEFICIENCY; DISEASE MODELS, ANIMAL; FEMALE; GADOLINIUM; GENETICS; MAGNETIC RESONANCE IMAGING; MALE; METABOLISM; MICE; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE TISSUE PROTEINS; PATHOLOGY; PERMEABILITY; PHARMACOKINETICS; PHYSIOPATHOLOGY; ULTRASTRUCTURE; VASCULAR CELL ADHESION MOLECULE-1; XANTHOMATOSIS;

EID: 84964301257     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.03.023     Document Type: Article

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