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Volumn 120, Issue 8, 2010, Pages 2782-2794

Angiotensin II sustains brain inflammation in mice via TGF-β

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; CANDESARTAN HEXETIL; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955300852     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI41709     Document Type: Article
Times cited : (178)

References (51)
  • 1
    • 43449134667 scopus 로고    scopus 로고
    • Update on tissue renin-angiotensin systems
    • Bader M, Ganten D. Update on tissue renin-angiotensin systems. J Mol Med. 2008;86(6):615-621.
    • (2008) J Mol Med , vol.86 , Issue.6 , pp. 615-621
    • Bader, M.1    Ganten, D.2
  • 2
    • 0032142834 scopus 로고    scopus 로고
    • Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart
    • Sun Y, Zhang JQ, Zhang J, Ramires FJ. Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart. J Mol Cell Cardiol. 1998;30(8):1559-1569.
    • (1998) J Mol Cell Cardiol , vol.30 , Issue.8 , pp. 1559-1569
    • Sun, Y.1    Zhang, J.Q.2    Zhang, J.3    Ramires, F.J.4
  • 3
    • 3042554688 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice
    • Nagashio Y, et al. Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice. Am J Physiol Gastrointest Liver Physiol. 2004;287(1):G170-G177.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , Issue.1
    • Nagashio, Y.1
  • 4
    • 16244376186 scopus 로고    scopus 로고
    • The renin-angiotensin system and the developing retinal vasculature
    • Sarlos S, Wilkinson-Berka JL. The renin-angiotensin system and the developing retinal vasculature. Invest Ophthalmol Vis Sci. 2005;46(3):1069-1077.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.3 , pp. 1069-1077
    • Sarlos, S.1    Wilkinson-Berka, J.L.2
  • 5
    • 0037059564 scopus 로고    scopus 로고
    • The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene
    • Morimoto S, Cassell MD, Sigmund CD. The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene. Circ Res. 2002;90(1):80-86.
    • (2002) Circ Res , vol.90 , Issue.1 , pp. 80-86
    • Morimoto, S.1    Cassell, M.D.2    Sigmund, C.D.3
  • 7
    • 0037366056 scopus 로고    scopus 로고
    • Control of dendritic cell differentiation by angiotensin II
    • Nahmod KA, et al. Control of dendritic cell differentiation by angiotensin II. FASEB J. 2003; 17(3):491-493.
    • (2003) FASEB J , vol.17 , Issue.3 , pp. 491-493
    • Nahmod, K.A.1
  • 8
    • 0344015781 scopus 로고    scopus 로고
    • Evidence that macrophages in atherosclerotic lesions contain angiotensin II
    • Potter DD, Sobey CG, Tompkins PK, Rossen JD, Heistad DD. Evidence that macrophages in atherosclerotic lesions contain angiotensin II. Circulation. 1998;98(8):800-807.
    • (1998) Circulation , vol.98 , Issue.8 , pp. 800-807
    • Potter, D.D.1    Sobey, C.G.2    Tompkins, P.K.3    Rossen, J.D.4    Heistad, D.D.5
  • 9
    • 33646199649 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor expression on human leukocyte subsets: A flow cytometric and RT-PCR study
    • Rasini E, et al. Angiotensin II type 1 receptor expression on human leukocyte subsets: a flow cytometric and RT-PCR study. Regul Pept. 2006;134(2-3):69-74.
    • (2006) Regul Pept , vol.134 , Issue.2-3 , pp. 69-74
    • Rasini, E.1
  • 10
    • 38149029057 scopus 로고    scopus 로고
    • Regulation of the renin-angiotensin system in coronary atherosclerosis: A review of the literature
    • Hammoud RA, Vaccari CS, Nagamia SH, Khan BV. Regulation of the renin-angiotensin system in coronary atherosclerosis: a review of the literature. Vasc Health Risk Manag. 2007;3(6):937-945.
    • (2007) Vasc Health Risk Manag , vol.3 , Issue.6 , pp. 937-945
    • Hammoud, R.A.1    Vaccari, C.S.2    Nagamia, S.H.3    Khan, B.V.4
  • 11
    • 20844442265 scopus 로고    scopus 로고
    • Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines
    • Nabah YN, et al. Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines. Circulation. 2004;110(23):3581-3586.
    • (2004) Circulation , vol.110 , Issue.23 , pp. 3581-3586
    • Nabah, Y.N.1
  • 12
    • 12344308309 scopus 로고    scopus 로고
    • The non-thiol angiotensin-converting enzyme inhibitor quinapril suppresses inflammatory arthritis
    • Dalbeth N, Edwards J, Fairchild S, Callan M, Hall FC. The non-thiol angiotensin-converting enzyme inhibitor quinapril suppresses inflammatory arthritis. Rheumatology (Oxford). 2005;44(1):24-31.
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.1 , pp. 24-31
    • Dalbeth, N.1    Edwards, J.2    Fairchild, S.3    Callan, M.4    Hall, F.C.5
  • 13
    • 20744436076 scopus 로고    scopus 로고
    • Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice
    • Sagawa K, Nagatani K, Komagata Y, Yamamoto K. Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice. Arthritis Rheum. 2005;52(6):1920-1928.
    • (2005) Arthritis Rheum , vol.52 , Issue.6 , pp. 1920-1928
    • Sagawa, K.1    Nagatani, K.2    Komagata, Y.3    Yamamoto, K.4
  • 14
    • 65549151327 scopus 로고    scopus 로고
    • Suppression of experimental autoimmune uveitis by angiotensin II type 1 receptor blocker telmisartan
    • Okunuki Y, et al. Suppression of experimental autoimmune uveitis by angiotensin II type 1 receptor blocker telmisartan. Invest Ophthalmol Vis Sci. 2009;50(5):2255-2261.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.5 , pp. 2255-2261
    • Okunuki, Y.1
  • 15
    • 70349267599 scopus 로고    scopus 로고
    • Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity
    • Platten M, et al. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proc Natl Acad Sci U S A. 2009;106(35):14948-14953.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.35 , pp. 14948-14953
    • Platten, M.1
  • 16
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor beta in human disease. N Engl J Med. 2000;342(18):1350-1358.
    • (2000) N Engl J Med , vol.342 , Issue.18 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 17
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol. 2007;8(4):345-350.
    • (2007) Nat Immunol , vol.8 , Issue.4 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 18
    • 36049051243 scopus 로고    scopus 로고
    • Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis
    • Luo J, et al. Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. J Clin Invest. 2007;117(11):3306-3315.
    • (2007) J Clin Invest , vol.117 , Issue.11 , pp. 3306-3315
    • Luo, J.1
  • 19
    • 48449086316 scopus 로고    scopus 로고
    • TGF-beta: A master of all T cell trades
    • Li MO, Flavell RA. TGF-beta: a master of all T cell trades. Cell. 2008;134(3):392-404.
    • (2008) Cell , vol.134 , Issue.3 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 20
    • 28444464515 scopus 로고    scopus 로고
    • Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions
    • Zhou Y, Poczatek MH, Berecek KH, Murphy-Ullrich JE. Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions. Biochem Biophys Res Commun. 2006;339(2):633-641.
    • (2006) Biochem Biophys Res Commun , vol.339 , Issue.2 , pp. 633-641
    • Zhou, Y.1    Poczatek, M.H.2    Berecek, K.H.3    Murphy-Ullrich, J.E.4
  • 21
    • 33846946114 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states
    • Cohn RD, et al. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med. 2007;13(2):204-210.
    • (2007) Nat Med , vol.13 , Issue.2 , pp. 204-210
    • Cohn, R.D.1
  • 22
    • 12344320716 scopus 로고    scopus 로고
    • Thrombospondin-1 is a major activator of TGF-beta1 in vivo
    • Crawford SE, et al. Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell. 1998; 93(7):1159-1170.
    • (1998) Cell , vol.93 , Issue.7 , pp. 1159-1170
    • Crawford, S.E.1
  • 23
    • 39849101009 scopus 로고    scopus 로고
    • Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
    • Han MH, et al. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 2008;451(7182):1076-1081.
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1076-1081
    • Han, M.H.1
  • 24
    • 62149150660 scopus 로고    scopus 로고
    • Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis
    • Yang K, et al. Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis. J Autoimmun. 2009;32(2):94-103.
    • (2009) J Autoimmun , vol.32 , Issue.2 , pp. 94-103
    • Yang, K.1
  • 25
    • 61949197524 scopus 로고    scopus 로고
    • Regulation of T-cell function by endogenously produced angiotensin II
    • Hoch NE, et al. Regulation of T-cell function by endogenously produced angiotensin II. Am J Physiol Regul Integr Comp Physiol. 2009;296(2):R208-R216.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296 , Issue.2
    • Hoch, N.E.1
  • 26
    • 0026006736 scopus 로고
    • Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1
    • Johns LD, Flanders KC, Ranges GE, Sriram S. Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J Immunol. 1991;147(6):1792-1796.
    • (1991) J Immunol , vol.147 , Issue.6 , pp. 1792-1796
    • Johns, L.D.1    Flanders, K.C.2    Ranges, G.E.3    Sriram, S.4
  • 29
    • 0028362076 scopus 로고
    • Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells
    • Kagami S, Border WA, Miller DE, Noble NA. Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest. 1994;93(6):2431-2437.
    • (1994) J Clin Invest , vol.93 , Issue.6 , pp. 2431-2437
    • Kagami, S.1    Border, W.A.2    Miller, D.E.3    Noble, N.A.4
  • 30
    • 0028789457 scopus 로고
    • Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts
    • Lee AA, Dillmann WH, McCulloch AD, Villarreal FJ. Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts. J Mol Cell Cardiol. 1995;27(10):2347-2357.
    • (1995) J Mol Cell Cardiol , vol.27 , Issue.10 , pp. 2347-2357
    • Lee, A.A.1    Dillmann, W.H.2    McCulloch, A.D.3    Villarreal, F.J.4
  • 31
    • 0032090939 scopus 로고    scopus 로고
    • Angiotensin II induces hypertrophy of human airway smooth muscle cells: Expression of transcription factors and transforming growth factor-beta1
    • McKay S, de Jongste JC, Saxena PR, Sharma HS. Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-beta1. Am J Respir Cell Mol Biol. 1998;18(6):823-833.
    • (1998) Am J Respir Cell Mol Biol , vol.18 , Issue.6 , pp. 823-833
    • McKay, S.1    De Jongste, J.C.2    Saxena, P.R.3    Sharma, H.S.4
  • 32
    • 0027312719 scopus 로고
    • Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta
    • Wolf G, Mueller E, Stahl RA, Ziyadeh FN. Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta. J Clin Invest. 1993;92(3):1366-1372.
    • (1993) J Clin Invest , vol.92 , Issue.3 , pp. 1366-1372
    • Wolf, G.1    Mueller, E.2    Stahl, R.A.3    Ziyadeh, F.N.4
  • 33
    • 33745199357 scopus 로고    scopus 로고
    • Highly sensitive and specific bioassay for measuring bioactive TGF-beta
    • Tesseur I, Zou K, Berber E, Zhang H, Wyss-Coray T. Highly sensitive and specific bioassay for measuring bioactive TGF-beta. BMC Cell Biol. 2006;7:15.
    • (2006) BMC Cell Biol , vol.7 , pp. 15
    • Tesseur, I.1    Zou, K.2    Berber, E.3    Zhang, H.4    Wyss-Coray, T.5
  • 34
    • 21244447539 scopus 로고    scopus 로고
    • Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury
    • Lin AH, et al. Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. J Immunol. 2005;175(1):547-554.
    • (2005) J Immunol , vol.175 , Issue.1 , pp. 547-554
    • Lin, A.H.1
  • 35
    • 33845287590 scopus 로고    scopus 로고
    • Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration
    • Luo J, Lin AH, Masliah E, Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc Natl Acad Sci U S A. 2006;103(48):18326-18331.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.48 , pp. 18326-18331
    • Luo, J.1    Lin, A.H.2    Masliah, E.3    Wyss-Coray, T.4
  • 36
    • 33845291617 scopus 로고    scopus 로고
    • F.D.A. U.S. Department of Health and Human Services, Center for Drug Evaluation and Research (CDER), ed. Rockville, Maryland, USA: US Food and Drug Administration
    • F.D.A. U.S. Department of Health and Human Services, Center for Drug Evaluation and Research (CDER), ed. Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers. Rockville, Maryland, USA: US Food and Drug Administration; 2005.
    • (2005) Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers
  • 37
    • 41049089072 scopus 로고    scopus 로고
    • Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease
    • Luo J, Ho P, Steinman L, Wyss-Coray T. Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease. J Neuroinflammation. 2008;5:6.
    • (2008) J Neuroinflammation , vol.5 , pp. 6
    • Luo, J.1    Ho, P.2    Steinman, L.3    Wyss-Coray, T.4
  • 38
    • 0033532054 scopus 로고    scopus 로고
    • The activation sequence of thrombospondin-1 interacts with the latencyassociated peptide to regulate activation of latent transforming growth factor-beta
    • Ribeiro SM, Poczatek M, Schultz-Cherry S, Villain M, Murphy-Ullrich JE. The activation sequence of thrombospondin-1 interacts with the latencyassociated peptide to regulate activation of latent transforming growth factor-beta. J Biol Chem. 1999;274(19):13586-13593.
    • (1999) J Biol Chem , vol.274 , Issue.19 , pp. 13586-13593
    • Ribeiro, S.M.1    Poczatek, M.2    Schultz-Cherry, S.3    Villain, M.4    Murphy-Ullrich, J.E.5
  • 39
    • 70349273755 scopus 로고    scopus 로고
    • Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system
    • Stegbauer J, et al. Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system. Proc Natl Acad Sci U S A. 2009;106(35):14942-14947.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.35 , pp. 14942-14947
    • Stegbauer, J.1
  • 40
    • 33646562542 scopus 로고    scopus 로고
    • The logic of TGFbeta signaling
    • Massague J, Gomis RR. The logic of TGFbeta signaling. FEBS Lett. 2006;580(12):2811-2820.
    • (2006) FEBS Lett , vol.580 , Issue.12 , pp. 2811-2820
    • Massague, J.1    Gomis, R.R.2
  • 42
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-beta
    • Letterio JJ, Roberts AB. Regulation of immune responses by TGF-beta. Annu Rev Immunol. 1998;16:137-161.
    • (1998) Annu Rev Immunol , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 43
    • 0025729912 scopus 로고
    • Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals
    • Brandes ME, Allen JB, Ogawa Y, Wahl SM. Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals. J Clin Invest. 1991;87(3):1108-1113.
    • (1991) J Clin Invest , vol.87 , Issue.3 , pp. 1108-1113
    • Brandes, M.E.1    Allen, J.B.2    Ogawa, Y.3    Wahl, S.M.4
  • 44
    • 0026656850 scopus 로고
    • Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice
    • Thorbecke GJ Shah R, Leu CH Kuruvilla AP, Hardison AM Palladino MA. Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice. Proc Natl Acad Sci U S A. 1992;89(16):7375-7379.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.16 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4    Hardison, A.M.5    Palladino, M.A.6
  • 45
    • 0030063832 scopus 로고    scopus 로고
    • Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse
    • Yaswen L, et al. Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse. Blood. 1996;87(4):1439-1445.
    • (1996) Blood , vol.87 , Issue.4 , pp. 1439-1445
    • Yaswen, L.1
  • 46
    • 0027392551 scopus 로고
    • Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta
    • Wahl SM, Allen JB, Costa GL, Wong HL, Dasch JR. Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta. J Exp Med. 1993;177(1):225-230.
    • (1993) J Exp Med , vol.177 , Issue.1 , pp. 225-230
    • Wahl, S.M.1    Allen, J.B.2    Costa, G.L.3    Wong, H.L.4    Dasch, J.R.5
  • 47
    • 0034998617 scopus 로고    scopus 로고
    • Participation of thrombospondin-1 in the activation of latent transforming growth factor-beta in malignant glioma cells
    • discussion 258-259
    • Sasaki A, Naganuma H, Satoh E, Kawataki T, Amagasaki K, Nukui H. Participation of thrombospondin-1 in the activation of latent transforming growth factor-beta in malignant glioma cells. Neurol Med Chir (Tokyo). 2001;41(5):253-258; discussion 258-259.
    • (2001) Neurol Med Chir (Tokyo) , vol.41 , Issue.5 , pp. 253-258
    • Sasaki, A.1    Naganuma, H.2    Satoh, E.3    Kawataki, T.4    Amagasaki, K.5    Nukui, H.6
  • 48
    • 0034426392 scopus 로고    scopus 로고
    • Correlation of thrombospondin-1 and transforming growth factor-beta expression with malignancy of glioma
    • Kawataki T, Naganuma H, Sasaki A, Yoshikawa H, Tasaka K, Nukui H. Correlation of thrombospondin-1 and transforming growth factor-beta expression with malignancy of glioma. Neuropathology. 2000;20(3):161-169.
    • (2000) Neuropathology , vol.20 , Issue.3 , pp. 161-169
    • Kawataki, T.1    Naganuma, H.2    Sasaki, A.3    Yoshikawa, H.4    Tasaka, K.5    Nukui, H.6
  • 49
    • 0028952503 scopus 로고
    • Regulation of blood pressure by the type 1A angiotensin II receptor gene
    • Ito M, et al. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc Natl Acad Sci U S A. 1995;92(8):3521-3525.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.8 , pp. 3521-3525
    • Ito, M.1
  • 50
    • 0038523790 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis
    • Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J Exp Med. 2003;197(9):1073-1081.
    • (2003) J Exp Med , vol.197 , Issue.9 , pp. 1073-1081
    • Bettelli, E.1    Pagany, M.2    Weiner, H.L.3    Linington, C.4    Sobel, R.A.5    Kuchroo, V.K.6
  • 51
    • 19944366634 scopus 로고    scopus 로고
    • Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection
    • Ousman SS, Wang J, Campbell IL. Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection. J Virol. 2005;79(12):7514-7527.
    • (2005) J Virol , vol.79 , Issue.12 , pp. 7514-7527
    • Ousman, S.S.1    Wang, J.2    Campbell, I.L.3


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