-
1
-
-
34247260551
-
Immunotherapy for renal cell cancer
-
Yang JC, Childs R. Immunotherapy for renal cell cancer. J Clin Oncol 2006; 24: 5576-83.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5576-5583
-
-
Yang, J.C.1
Childs, R.2
-
2
-
-
84877898781
-
Intrinsic immune alterations in renal cell carcinoma and emerging immunotherapeutic approaches
-
Bockorny B, Dasanu CA. Intrinsic immune alterations in renal cell carcinoma and emerging immunotherapeutic approaches. Expert Opin Biol Ther 2013; 13: 911-25.
-
(2013)
Expert Opin Biol Ther
, vol.13
, pp. 911-925
-
-
Bockorny, B.1
Dasanu, C.A.2
-
3
-
-
84888295105
-
Targeted therapies and complete responses in first line treatment of metastatic renal cell carcinoma. A meta-analysis of published trials
-
Iacovelli R, Alesini D, Palazzo A, et al. Targeted therapies and complete responses in first line treatment of metastatic renal cell carcinoma. A meta-analysis of published trials. Cancer Treat Rev 2014; 40: 271-5.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 271-275
-
-
Iacovelli, R.1
Alesini, D.2
Palazzo, A.3
-
4
-
-
84859128199
-
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
Taube JM, Anders RA, Young GD, et al. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med 2012; 4: 127ra37.
-
(2012)
Sci Transl Med
, vol.4
-
-
Taube, J.M.1
Ers, R.A.2
Young, G.D.3
-
5
-
-
84905496988
-
PD-1 expression on peripheral blood cells increases with stage in renal cell carcinoma patients and is rapidly reduced after surgical tumor resection
-
MacFarlane AWt, Jillab M, Plimack ER, et al. PD-1 expression on peripheral blood cells increases with stage in renal cell carcinoma patients and is rapidly reduced after surgical tumor resection. Cancer Immunol Res 2014; 2: 320-31.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 320-331
-
-
Macfarlane, A.1
Jillab, M.2
Plimack, E.R.3
-
6
-
-
27644562256
-
Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
-
Thompson RH, Gillett MD, Cheville JC, et al. Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma. Cancer 2005; 104: 2084-91.
-
(2005)
Cancer
, vol.104
, pp. 2084-2091
-
-
Thompson, R.H.1
Gillett, M.D.2
Cheville, J.C.3
-
7
-
-
84984919880
-
PD-L1 expression in nonclear- cell renal cell carcinoma
-
Choueiri TK, Fay AP, Gray KP, et al. PD-L1 expression in nonclear- cell renal cell carcinoma. Ann Oncol 2014; 25: 2178-84.
-
(2014)
Ann Oncol
, vol.25
, pp. 2178-2184
-
-
Choueiri, T.K.1
Fay, A.P.2
Gray, K.P.3
-
8
-
-
33748987908
-
Cancer despite immunosurveillance: Immunoselection and immunosubversion
-
Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 2006; 6: 715-27.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 715-727
-
-
Zitvogel, L.1
Tesniere, A.2
Kroemer, G.3
-
9
-
-
84921779027
-
PD-1 blockade therapy in renal cell carcinoma: Current studies and future promises
-
Massari F, Santoni M, Ciccarese C, et al. PD-1 blockade therapy in renal cell carcinoma: current studies and future promises. Cancer Treat Rev 2015; 41: 114-21.
-
(2015)
Cancer Treat Rev
, vol.41
, pp. 114-121
-
-
Massari, F.1
Santoni, M.2
Ciccarese, C.3
-
10
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8: 793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
-
11
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002; 99: 12293-7.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
12
-
-
10344220548
-
Costimulatory B7- H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
-
Thompson RH, Gillett MD, Cheville JC, et al. Costimulatory B7- H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. Proc Natl Acad Sci USA 2004; 101: 17174-9.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17174-17179
-
-
Thompson, R.H.1
Gillett, M.D.2
Cheville, J.C.3
-
13
-
-
34250177269
-
PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
-
Thompson RH, Dong H, Lohse CM, et al. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res 2007; 13: 1757-61.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1757-1761
-
-
Thompson, R.H.1
Dong, H.2
Lohse, C.M.3
-
14
-
-
77954899030
-
Phase I study of singleagent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, et al. Phase I study of singleagent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010; 28: 3167-75.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
15
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
16
-
-
84929572937
-
Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial
-
Motzer RJ, Rini BI, McDermott DF, et al. Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial. J Clin Oncol 2015; 33(13): 1430-7.
-
(2015)
J Clin Oncol
, vol.33
, Issue.13
, pp. 1430-1437
-
-
Motzer, R.J.1
Rini, B.I.2
McDermott, D.F.3
-
17
-
-
84921742040
-
Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (MRCC): Biomarker-based results from a randomized clinical trial
-
abstr 5012
-
Choueiri TF, Fishman MN, Escudier BJ, et al. Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): Biomarker-based results from a randomized clinical trial. J Clin Oncol 2014; 32(15 suppl): abstr 5012.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Choueiri, T.F.1
Fishman, M.N.2
Escudier, B.J.3
-
18
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012; 366: 2455-65.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
19
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014; 515: 563-7.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
-
20
-
-
79961093008
-
Monitoring T-cell responses in a phase II study of AGS-003, an autologous dendritic cell-based therapy in patients with newly diagnosed advanced stage renal cell carcinoma in combination with sunitinib
-
(Suppl Abstract 2532)
-
Figlin RA, Nicolette CA, Amin A, et al. Monitoring T-cell responses in a phase II study of AGS-003, an autologous dendritic cell-based therapy in patients with newly diagnosed advanced stage renal cell carcinoma in combination with sunitinib. J Clin Oncol 2011; 29: (Suppl Abstract 2532).
-
(2011)
J Clin Oncol
, pp. 29
-
-
Figlin, R.A.1
Nicolette, C.A.2
Amin, A.3
-
21
-
-
77958015499
-
Results of a randomized phase II study investigating multipeptide vaccination with IMA901 in advanced renal cell carcinoma (RCC)
-
(Suppl Abstract 4529)
-
Reinhardt C, Zdrojowy R, Szczylik C, et al. Results of a randomized phase II study investigating multipeptide vaccination with IMA901 in advanced renal cell carcinoma (RCC). J Clin Oncol 2010; 28: (Suppl Abstract 4529).
-
(2010)
J Clin Oncol
, pp. 28
-
-
Reinhardt, C.1
Zdrojowy, R.2
Szczylik, C.3
-
22
-
-
68449100522
-
Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) alone or administered in combination with interferon-alpha (IFN-alpha): A phase 2 trial
-
Amato RJ, Shingler W, Goonewardena M, et al. Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) alone or administered in combination with interferon-alpha (IFN-alpha): a phase 2 trial. J Immunother 2009; 32: 765-72.
-
(2009)
J Immunother
, vol.32
, pp. 765-772
-
-
Amato, R.J.1
Shingler, W.2
Goonewardena, M.3
-
23
-
-
37349072460
-
Ipilimumab (Anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis
-
Yang JC, Hughes M, Kammula U, et al. Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis. J Immunother 2007; 30: 825-30.
-
(2007)
J Immunother
, vol.30
, pp. 825-830
-
-
Yang, J.C.1
Hughes, M.2
Kammula, U.3
-
24
-
-
22144496809
-
Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes
-
Engels B, Noessner E, Frankenberger B, Blankenstein T, Schendel DJ, Uckert W. Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes. Hum Gene Ther 2005; 16: 799-810.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 799-810
-
-
Engels, B.1
Noessner, E.2
Frankenberger, B.3
Blankenstein, T.4
Schendel, D.J.5
Uckert, W.6
-
25
-
-
77955175181
-
A pilot study of denileukin diftitox (DD) in combination with high-dose interleukin-2 (IL-2) for patients with metastatic renal cell carcinoma (RCC)
-
Atchison E, Eklund J, Martone B, et al. A pilot study of denileukin diftitox (DD) in combination with high-dose interleukin-2 (IL-2) for patients with metastatic renal cell carcinoma (RCC). J Immunother 2010; 33: 716-22.
-
(2010)
J Immunother
, vol.33
, pp. 716-722
-
-
Atchison, E.1
Eklund, J.2
Martone, B.3
-
26
-
-
84964206427
-
Induction of HLA-A*33- restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH
-
Kawashima H, Masaki S, Kawamura M. Induction of HLA-A*33- restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH. Biomed Rep 2014; 2: 809-12.
-
(2014)
Biomed Rep
, vol.2
, pp. 809-812
-
-
Kawashima, H.1
Masaki, S.2
Kawamura, M.3
-
27
-
-
63549105681
-
Sunitinib mediates reversal of myeloid- derived suppressor cell accumulation in renal cell carcinoma patients
-
Ko JS, Zea AH, Rini BI, et al. Sunitinib mediates reversal of myeloid- derived suppressor cell accumulation in renal cell carcinoma patients. Clin Cancer Res 2009; 15: 2148-57.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
-
28
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 2013; 369: 122-33.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
29
-
-
79960299888
-
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
-
Rosenberg SA, Yang JC, Sherry RM, et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011; 17: 4550-7.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4550-4557
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
30
-
-
84884889096
-
Progress of molecular targeted therapies for advanced renal cell carcinoma
-
2013
-
Conti A, Santoni M, Amantini C, et al. Progress of molecular targeted therapies for advanced renal cell carcinoma. Biomed Res Int 2013; 2013: 419176.
-
(2013)
Biomed Res Int
-
-
Conti, A.1
Santoni, M.2
Amantini, C.3
-
32
-
-
84923118889
-
PVHL/HIF-regulated CD70 expression is associated with infiltration of CD27+ lymphocytes and increased serum levels of soluble CD27 in clear cell renal cell carcinoma
-
Ruf M, Mittmann C, Nowicka AM, et al. pVHL/HIF-regulated CD70 expression is associated with infiltration of CD27+ lymphocytes and increased serum levels of soluble CD27 in clear cell renal cell carcinoma. Clin Cancer Res 2015; 21: 889-98.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 889-898
-
-
Ruf, M.1
Mittmann, C.2
Nowicka, A.M.3
|