The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation

eLife

Volumn 5, Issue MARCH2016, 2016, Pages

  Yonashiro, Ryo ^a   Tahara, Erich B ^a,e   Bengtson, Mario H ^a,f   Khokhrina, Maria ^b   Lorenz, Holger ^b   Chen, Kai Chun ^a   Kigoshi Tansho, Yu ^a   Savas, Jeffrey N ^a,g   Yates, John R ^a   Kay, Steve A ^a   Craig, Elizabeth A ^c   Mogk, Axel ^b   Bukau, Bernd ^b   Joazeiro, Claudio A P ^a,d  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b GERMAN CANCER RESEARCH CENTER   (Germany)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^f UNIVERSITY OF CAMPINAS   (Brazil)

^g NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GREEN FLUORESCENT PROTEIN; LISTERIN E3 UBIQUITIN PROTEIN LIGASE 1; POLYPEPTIDE; PROTEIN AGGREGATE; RIBOSOME ASSOCIATED QUALITY CONTROL COMPLEX; RIBOSOME ASSOCIATED QUALITY CONTROL COMPLEX 2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; PEPTIDE; RNA BINDING PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TAE2 PROTEIN, S CEREVISIAE;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION AND TRANSLATION; IMMUNOBLOTTING; MASS SPECTROMETRY; PHENOTYPE; PROTEIN ANALYSIS; QUALITY CONTROL; RIBOSOME STALLING; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; METABOLISM; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEINOSIS; RIBOSOME; SACCHAROMYCES CEREVISIAE;

PEPTIDES; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBOSOMES; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84964290546     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11794     Document Type: Article

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