Long-term efficacy and safety of common steroid-sparing agents in idiopathic nephrotic children

Clinical and Experimental Nephrology

Volumn 21, Issue 1, 2017, Pages 143-151

  Basu, Biswanath ^a   Babu, Binu George ^a,b   Mahapatra, T K S ^a  

^a NRS MEDICAL COLLEGE   (India)

^b Caritas Hospital   (India)

Author keywords

Levamisole; Mycophenolate mofetil; Nephrotic syndrome; Tacrolimus

Indexed keywords

ALBUMIN; ANTIBIOTIC AGENT; CHOLESTEROL; CREATININE; LEVAMISOLE; LIVER ENZYME; MYCOPHENOLATE MOFETIL; PREDNISOLONE; TACROLIMUS; CALCINEURIN INHIBITOR; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID;

ABDOMINAL PAIN; ABSCESS; ACUTE GASTROENTERITIS; ACUTE HEPATITIS; ALOPECIA; ARTICLE; BACTERIAL PERITONITIS; BACTERIAL PNEUMONIA; CHILD; CHOLESTEROL BLOOD LEVEL; CHRONIC PAIN; COHORT ANALYSIS; CONVULSION; CREATININE BLOOD LEVEL; DISEASE DURATION; DRUG CHOICE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; ECZEMA; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HERPES SIMPLEX; HIRSUTISM; HUMAN; HYPERGLYCEMIA; HYPERTRANSAMINASEMIA; IDIOPATHIC DISEASE; LEUKOPENIA; MAJOR CLINICAL STUDY; MALARIA; MALE; MOOD CHANGE; MOOD DISORDER; MYALGIA; NEPHROTIC SYNDROME; PANCREATITIS; PERITONITIS; RECURRENCE FREE SURVIVAL; RECURRENCE RISK; RELAPSE; REMISSION; RESPIRATORY TRACT INFECTION; RETROSPECTIVE STUDY; STOMATITIS; URINARY TRACT INFECTION; VOMITING; ADOLESCENT; COMPARATIVE STUDY; DISEASE FREE SURVIVAL; DRUG ADMINISTRATION; INFANT; PRESCHOOL CHILD; RECURRENT DISEASE; TIME FACTOR; TREATMENT OUTCOME;

ADOLESCENT; CALCINEURIN INHIBITORS; CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; LEVAMISOLE; MALE; MYCOPHENOLIC ACID; NEPHROTIC SYNDROME; PREDNISOLONE; RECURRENCE; RETROSPECTIVE STUDIES; TACROLIMUS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84964252237     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-016-1266-8     Document Type: Article

References (19)

1. Pravitsitthikul N, Willis NS, Hodson EM, et al. Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children. Cochrane Database Syst Rev. 2013;10:CD002290.
2. Lombel RM, Gipson DS, Hodson EM. Kidney disease: improving global outcomes. Treatment of steroid-sensitive nephrotic syndrome: new guidelines from KDIGO. Pediatr Nephrol. 2013;28:415–26.
3. Schwartz GJ, Munoz A, Schneider MF, et al. New equations to estimate GFR inchildren with CKD. J Am Soc Nephrol. 2009;20:629–37.
4. British Association for Paediatric Nephrology. Levamisole for corticosteroid-dependent nephrotic syndrome in childhood. Lancet. 1991;337:1555–7.
5. Dayal U, Dayal AK, Shastry JC, et al. Use of levamisole in maintaining remission in steroid-sensitive nephrotic syndrome in children. Nephron. 1994;66:408–12.
6. Donia AF, Ammar HM, El-AgroudyAel-B, et al. Long-term results of two unconventional agents in steroid-dependent nephrotic children. Pediatr Nephrol. 2005;20:1420–5.
7. Al Saran K, Mirza K, Al Ghanam G, et al. Experience with levamisole in frequently relapsing, steroid dependent nephrotic syndrome. Pediatr Nephrol. 2006;21:201–5.
8. Dorresteijn EM, Kist-van Holthe JE, Levtchenko EN, et al. Mycophenolatemofetil versus cyclosporine for remission maintenance in nephrotic syndrome. Pediatr Nephrol. 2008;23:2013–20.
9. Baudouin V, Alberti C, Lapeyraque AL, et al. Mycophenolatemofetil for steroid-dependent nephrotic syndrome: a phase II Bayesian trial. Pediatr Nephrol. 2012;27:389–96.
10. Gellermann J, Weber L, Pape L, Gesellschaft für Pädiatrische Nephrologie (GPN), et al. Mycophenolate mofetil versus cyclosporin A in children with frequently relapsing nephrotic syndrome. J Am Soc Nephrol. 2013;24:1689–97.
11. Ponticelli C, Edefonti A, Ghio L, et al. Cyclosporin versus cyclophosphamide for patients with steroid-dependent and frequently relapsing idiopathic nephrotic syndrome: a multicentre randomized controlled trial. Nephrol Dial Transpl. 1993;8:1326–32.
12. Ishikura K, Ikeda M, Hattori S, et al. Effective and safe treatment with cyclosporine in nephrotic children: a prospective, randomized multicenter trial. Kidney Int. 2008;73:1167–73.
13. Wang W, Xia Y, Mao J, et al. Treatment of tacrolimus or cyclosporine A in children with idiopathic nephrotic syndrome. Pediatr Nephrol. 2012;27:2073–9.
14. Barratt TM, Cameron JS, Chantler C, et al. Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood. Arch Dis Child. 1973;48:286–90.
15. Ueda N, Kuno K, Ito S. Eight and 12 week courses of cyclophosphamide in nephrotic syndrome. Arch Dis Child. 1990;65:1147–50.
16. Prasad N, Gulati S, Sharma RK, et al. Pulse cyclophosphamide therapy in steroid-dependent nephrotic syndrome. Pediatr Nephrol. 2004;19:494–8.
17. Kamei K, Ito S, Nozu K, et al. Single dose of rituximab for refractory steroid-dependent nephrotic syndrome in children. Pediatr Nephrol. 2009;24:1321–8.
18. Iijima K, Sako M, Nozu K, et al. Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet. 2014;384:1273–81.
19. Ruggenenti P, Ruggiero B, Cravedi P, et al. Rituximab in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome. J Am Soc Nephrol. 2014;25:850–63.