Dexmedetomidine attenuates inflammatory reaction in the lung tissues of septic mice by activating cholinergic anti-inflammatory pathway

International Immunopharmacology

Volumn 35, Issue , 2016, Pages 210-216

  Liu, Zhaoguo ^a   Wang, Yueping ^a   Wang, Yaoqi ^a   Ning, Qiaoqing ^a   Zhang, Yong ^a   Gong, Chunzhi ^a   Zhao, Wenxiang ^a   Jing, Guangjian ^a   Wang, Qianqian ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Cholinergic anti inflammatory pathway; Dexmedetomidine; Lipopolysaccharides; Lung; Sepsis

Indexed keywords

ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; DEXMEDETOMIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIINFLAMMATORY AGENT; BUNGAROTOXIN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME ACTIVITY; HISTOPATHOLOGY; LUNG EDEMA; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SURVIVAL RATE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PNEUMONIA; SIGNAL TRANSDUCTION;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; ANTI-INFLAMMATORY AGENTS; BUNGAROTOXINS; DEXMEDETOMIDINE; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; PNEUMONIA; SEPSIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84964009381     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2016.04.003     Document Type: Article

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