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Volumn 15, Issue 5, 2016, Pages 935-943

Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia

Author keywords

[No Author keywords available]

Indexed keywords

EPS8 PROTEIN; ISOPROTEIN; PDZ PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; WHIRLIN; MEMBRANE PROTEIN; WHRN PROTEIN, MOUSE;

EID: 84963988160     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.03.081     Document Type: Article
Times cited : (31)

References (27)
  • 2
    • 16344381942 scopus 로고    scopus 로고
    • Sound-induced motions of individual cochlear hair bundles
    • Aranyosi A.J., Freeman D.M. Sound-induced motions of individual cochlear hair bundles. Biophys. J. 2004, 87:3536-3546.
    • (2004) Biophys. J. , vol.87 , pp. 3536-3546
    • Aranyosi, A.J.1    Freeman, D.M.2
  • 8
    • 73349103467 scopus 로고    scopus 로고
    • Hearing loss: mechanisms revealed by genetics and cell biology
    • Dror A.A., Avraham K.B. Hearing loss: mechanisms revealed by genetics and cell biology. Annu. Rev. Genet. 2009, 43:411-437.
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 411-437
    • Dror, A.A.1    Avraham, K.B.2
  • 9
    • 33947148611 scopus 로고    scopus 로고
    • A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss
    • Ebermann I., Scholl H.P., Charbel Issa P., Becirovic E., Lamprecht J., Jurklies B., Millán J.M., Aller E., Mitter D., Bolz H. A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss. Hum. Genet. 2007, 121:203-211.
    • (2007) Hum. Genet. , vol.121 , pp. 203-211
    • Ebermann, I.1    Scholl, H.P.2    Charbel Issa, P.3    Becirovic, E.4    Lamprecht, J.5    Jurklies, B.6    Millán, J.M.7    Aller, E.8    Mitter, D.9    Bolz, H.10
  • 11
    • 0035884807 scopus 로고    scopus 로고
    • FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel
    • Gale J.E., Marcotti W., Kennedy H.J., Kros C.J., Richardson G.P. FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel. J. Neurosci. 2001, 21:7013-7025.
    • (2001) J. Neurosci. , vol.21 , pp. 7013-7025
    • Gale, J.E.1    Marcotti, W.2    Kennedy, H.J.3    Kros, C.J.4    Richardson, G.P.5
  • 12
    • 84877980964 scopus 로고    scopus 로고
    • The composition and role of cross links in mechanoelectrical transduction in vertebrate sensory hair cells
    • Hackney C.M., Furness D.N. The composition and role of cross links in mechanoelectrical transduction in vertebrate sensory hair cells. J. Cell Sci. 2013, 126:1721-1731.
    • (2013) J. Cell Sci. , vol.126 , pp. 1721-1731
    • Hackney, C.M.1    Furness, D.N.2
  • 13
    • 0026755854 scopus 로고
    • The development and interpretation of the summating potential response
    • Harvey D., Steel K.P. The development and interpretation of the summating potential response. Hear. Res. 1992, 61:137-146.
    • (1992) Hear. Res. , vol.61 , pp. 137-146
    • Harvey, D.1    Steel, K.P.2
  • 14
    • 0037068004 scopus 로고    scopus 로고
    • Elongation of hair cell stereocilia is defective in the mouse mutant whirler
    • Holme R.H., Kiernan B.W., Brown S.D., Steel K.P. Elongation of hair cell stereocilia is defective in the mouse mutant whirler. J. Comp. Neurol. 2002, 450:94-102.
    • (2002) J. Comp. Neurol. , vol.450 , pp. 94-102
    • Holme, R.H.1    Kiernan, B.W.2    Brown, S.D.3    Steel, K.P.4
  • 15
    • 79151470659 scopus 로고    scopus 로고
    • Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8
    • Manor U., Disanza A., Grati M., Andrade L., Lin H., Di Fiore P.P., Scita G., Kachar B. Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Curr. Biol. 2011, 21:167-172.
    • (2011) Curr. Biol. , vol.21 , pp. 167-172
    • Manor, U.1    Disanza, A.2    Grati, M.3    Andrade, L.4    Lin, H.5    Di Fiore, P.P.6    Scita, G.7    Kachar, B.8
  • 16
    • 84959236550 scopus 로고    scopus 로고
    • A study of whirlin isoforms in the mouse vestibular system suggests potential vestibular dysfunction in DFNB31-deficient patients
    • Mathur P.D., Vijayakumar S., Vashist D., Jones S.M., Jones T.A., Yang J. A study of whirlin isoforms in the mouse vestibular system suggests potential vestibular dysfunction in DFNB31-deficient patients. Hum. Mol. Genet. 2015, 24:7017-7030.
    • (2015) Hum. Mol. Genet. , vol.24 , pp. 7017-7030
    • Mathur, P.D.1    Vijayakumar, S.2    Vashist, D.3    Jones, S.M.4    Jones, T.A.5    Yang, J.6
  • 20
    • 34250366660 scopus 로고    scopus 로고
    • The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development
    • Mogensen M.M., Rzadzinska A., Steel K.P. The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development. Cell Motil. Cytoskeleton 2007, 64:496-508.
    • (2007) Cell Motil. Cytoskeleton , vol.64 , pp. 496-508
    • Mogensen, M.M.1    Rzadzinska, A.2    Steel, K.P.3
  • 25
    • 33144483509 scopus 로고    scopus 로고
    • Identification of a novel frameshift mutation in the DFNB31/WHRN gene in a Tunisian consanguineous family with hereditary non-syndromic recessive hearing loss
    • Tlili A., Charfedine I., Lahmar I., Benzina Z., Mohamed B.A., Weil D., Idriss N., Drira M., Masmoudi S., Ayadi H. Identification of a novel frameshift mutation in the DFNB31/WHRN gene in a Tunisian consanguineous family with hereditary non-syndromic recessive hearing loss. Hum. Mutat. 2005, 25:503.
    • (2005) Hum. Mutat. , vol.25 , pp. 503
    • Tlili, A.1    Charfedine, I.2    Lahmar, I.3    Benzina, Z.4    Mohamed, B.A.5    Weil, D.6    Idriss, N.7    Drira, M.8    Masmoudi, S.9    Ayadi, H.10
  • 26
  • 27
    • 84897522568 scopus 로고    scopus 로고
    • Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice
    • Zou J., Zheng T., Ren C., Askew C., Liu X.P., Pan B., Holt J.R., Wang Y., Yang J. Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice. Hum. Mol. Genet. 2014, 23:2374-2390.
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 2374-2390
    • Zou, J.1    Zheng, T.2    Ren, C.3    Askew, C.4    Liu, X.P.5    Pan, B.6    Holt, J.R.7    Wang, Y.8    Yang, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.