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Volumn 23, Issue 5, 2016, Pages 360-369

Current status of primary pharmacotherapy and future perspectives toward upfront therapy for metastatic hormone-sensitive prostate cancer

Author keywords

Abiraterone acetate; Androgen deprivation therapy; Enzalutamide; Hormone sensitive prostate cancer; Taxane

Indexed keywords

ABIRATERONE ACETATE; ANTIANDROGEN; ANTINEOPLASTIC AGENT; APALUTAMIDE; BICALUTAMIDE; CABAZITAXEL; CABOZANTINIB; CHLORMADINONE ACETATE; CYPROTERONE ACETATE; DOCETAXEL; ENZALUTAMIDE; ESTROGEN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; MEDROXYPROGESTERONE ACETATE; MEGESTROL ACETATE; METFORMIN; ORTERONEL; PLACEBO; RADIOPHARMACEUTICAL AGENT; RADIUM 223; TUMOR MARKER; UNCLASSIFIED DRUG; ZOLEDRONIC ACID; TAXOID;

EID: 84963860981     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/iju.13091     Document Type: Review
Times cited : (69)

References (110)
  • 2
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth
    • Montgomery RB, Mostaghel EA, Vessella R et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 2008; 68: 4447-54.
    • (2008) Cancer Res. , vol.68 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3
  • 3
    • 0028173882 scopus 로고
    • Steroid 5α-reductase: two genes/two enzymes
    • Russell DW, Wilson JD. Steroid 5α-reductase: two genes/two enzymes. Annu. Rev. Biochem. 1994; 63: 25-61.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 25-61
    • Russell, D.W.1    Wilson, J.D.2
  • 4
    • 28844481089 scopus 로고    scopus 로고
    • Molecular chaperones throughout the life cycle of the androgen receptor
    • Prescott J, Coetzee GA. Molecular chaperones throughout the life cycle of the androgen receptor. Cancer Lett. 2006; 231: 12-9.
    • (2006) Cancer Lett. , vol.231 , pp. 12-19
    • Prescott, J.1    Coetzee, G.A.2
  • 5
    • 80051692745 scopus 로고    scopus 로고
    • Androgen receptor cofactors in prostate cancer: potential therapeutic targets of castration-resistant prostate cancer
    • Shiota M, Yokomizo A, Fujimoto N, Naito S. Androgen receptor cofactors in prostate cancer: potential therapeutic targets of castration-resistant prostate cancer. Curr. Cancer Drug Targets 2011; 11: 870-81.
    • (2011) Curr. Cancer Drug Targets , vol.11 , pp. 870-881
    • Shiota, M.1    Yokomizo, A.2    Fujimoto, N.3    Naito, S.4
  • 6
    • 84869207260 scopus 로고    scopus 로고
    • Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer
    • Shiota M, Yokomizo A, Naito S. Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer. Endocr. Relat. Cancer 2012; 19: R243-53.
    • (2012) Endocr. Relat. Cancer , vol.19 , pp. R243-R253
    • Shiota, M.1    Yokomizo, A.2    Naito, S.3
  • 7
    • 84928580276 scopus 로고
    • Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C, Hodges CV. Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1941; 1: 293-7.
    • (1941) Cancer Res. , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 8
    • 84983471998 scopus 로고    scopus 로고
    • Androgen deprivation therapy and secondary hormone therapy in the management of hormone-sensitive and castration-resistant prostate cancer
    • Saad F, Fizazi K. Androgen deprivation therapy and secondary hormone therapy in the management of hormone-sensitive and castration-resistant prostate cancer. Urology 2015; 86: 852-61.
    • (2015) Urology , vol.86 , pp. 852-861
    • Saad, F.1    Fizazi, K.2
  • 9
    • 84964266910 scopus 로고    scopus 로고
    • Adverse effects of androgen-deprivation therapy in prostate cancer and their management
    • Rhee H, Gunter JH, Heathcote P et al. Adverse effects of androgen-deprivation therapy in prostate cancer and their management. BJU Int. 2015; 115: 3-13.
    • (2015) BJU Int. , vol.115 , pp. 3-13
    • Rhee, H.1    Gunter, J.H.2    Heathcote, P.3
  • 10
    • 84878667224 scopus 로고    scopus 로고
    • Castration-resistant prostate cancer: novel therapeutics pre- or post- taxane administration
    • Shiota M, Yokomizo A, Fujimoto N, Kuruma H, Naito S. Castration-resistant prostate cancer: novel therapeutics pre- or post- taxane administration. Curr. Cancer Drug Targets 2013; 13: 444-59.
    • (2013) Curr. Cancer Drug Targets , vol.13 , pp. 444-459
    • Shiota, M.1    Yokomizo, A.2    Fujimoto, N.3    Kuruma, H.4    Naito, S.5
  • 11
    • 84940484592 scopus 로고    scopus 로고
    • Novel agents for castration-resistant prostate cancer: early experience and beyond
    • Fujimoto N. Novel agents for castration-resistant prostate cancer: early experience and beyond. Int. J. Urol. 2016; 23: 114-21.
    • (2016) Int. J. Urol. , vol.23 , pp. 114-121
    • Fujimoto, N.1
  • 12
    • 34248169161 scopus 로고    scopus 로고
    • Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline
    • Loblaw DA, Virgo KS, Nam R et al. Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline. J. Clin. Oncol. 2007; 25: 1596-605.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1596-1605
    • Loblaw, D.A.1    Virgo, K.S.2    Nam, R.3
  • 13
    • 84891809097 scopus 로고    scopus 로고
    • EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer
    • Heidenreich A, Bastian PJ, Bellmunt J et al. EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur. Urol. 2014; 65: 467-79.
    • (2014) Eur. Urol. , vol.65 , pp. 467-479
    • Heidenreich, A.1    Bastian, P.J.2    Bellmunt, J.3
  • 14
    • 84951567482 scopus 로고    scopus 로고
    • Trans-Pacific variation in outcomes for men treated with primary androgen-deprivation therapy (ADT) for prostate cancer
    • Cooperberg MR, Hinotsu S, Namiki M, Carroll PR, Akaza H. Trans-Pacific variation in outcomes for men treated with primary androgen-deprivation therapy (ADT) for prostate cancer. BJU Int. 2016; 117: 102-9.
    • (2016) BJU Int. , vol.117 , pp. 102-109
    • Cooperberg, M.R.1    Hinotsu, S.2    Namiki, M.3    Carroll, P.R.4    Akaza, H.5
  • 15
    • 84927948461 scopus 로고    scopus 로고
    • Reimbursement cuts and changes in urologist use of androgen deprivation therapy for prostate cancer
    • Shahinian VB, Kuo YF. Reimbursement cuts and changes in urologist use of androgen deprivation therapy for prostate cancer. BMC Urol. 2015; 15: 25.
    • (2015) BMC Urol. , vol.15 , pp. 25
    • Shahinian, V.B.1    Kuo, Y.F.2
  • 16
    • 0141988879 scopus 로고    scopus 로고
    • The nonsteroidal effects of diethylstilbestrol: the rationale for androgen deprivation therapy without estrogen deprivation in the treatment of prostate cancer
    • Scherr DS, Pitts WR Jr. The nonsteroidal effects of diethylstilbestrol: the rationale for androgen deprivation therapy without estrogen deprivation in the treatment of prostate cancer. J. Urol. 2003; 170: 1703-8.
    • (2003) J. Urol. , vol.170 , pp. 1703-1708
    • Scherr, D.S.1    Pitts, W.R.2
  • 17
    • 0022615138 scopus 로고
    • Cardiovascular side effects of diethylstilbestrol, cyproterone acetate, medroxyprogesterone acetate and estramustine phosphate used for the treatment of advanced prostatic cancer: results from European Organization for Research on Treatment of Cancer trials 30761 and 30762
    • de Voogt HJ, Smith PH, Pavone-Macaluso M, de Pauw M, Suciu S. Cardiovascular side effects of diethylstilbestrol, cyproterone acetate, medroxyprogesterone acetate and estramustine phosphate used for the treatment of advanced prostatic cancer: results from European Organization for Research on Treatment of Cancer trials 30761 and 30762. J. Urol. 1986; 135: 303-7.
    • (1986) J. Urol. , vol.135 , pp. 303-307
    • de Voogt, H.J.1    Smith, P.H.2    Pavone-Macaluso, M.3    de Pauw, M.4    Suciu, S.5
  • 18
  • 19
    • 0026250816 scopus 로고
    • Leuprorelin. A review of its pharmacology and therapeutic use in prostatic disorders
    • Chrisp P, Sorkin EM. Leuprorelin. A review of its pharmacology and therapeutic use in prostatic disorders. Drugs Aging 1991; 1: 487-509.
    • (1991) Drugs Aging , vol.1 , pp. 487-509
    • Chrisp, P.1    Sorkin, E.M.2
  • 20
  • 21
    • 0021721387 scopus 로고
    • Leuprolide versus diethylstilbestrol for metastatic prostate cancer
    • The Leuprolide Study Group. Leuprolide versus diethylstilbestrol for metastatic prostate cancer. N. Engl. J. Med. 1984; 311: 1281-6.
    • (1984) N. Engl. J. Med. , vol.311 , pp. 1281-1286
  • 22
    • 0034603826 scopus 로고    scopus 로고
    • Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis
    • Seidenfeld J, Samson DJ, Hasselblad V et al. Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis. Ann. Intern. Med. 2000; 132: 566-77.
    • (2000) Ann. Intern. Med. , vol.132 , pp. 566-577
    • Seidenfeld, J.1    Samson, D.J.2    Hasselblad, V.3
  • 23
    • 0032126847 scopus 로고    scopus 로고
    • Comparison of goserelin and leuprolide in combined androgen blockade therapy
    • Sarosdy MF, Schellhammer PF, Sharifi R et al. Comparison of goserelin and leuprolide in combined androgen blockade therapy. Urology 1998; 52: 82-8.
    • (1998) Urology , vol.52 , pp. 82-88
    • Sarosdy, M.F.1    Schellhammer, P.F.2    Sharifi, R.3
  • 24
    • 0022367715 scopus 로고
    • Importance of early tumour exacerbation in patients treated with long acting analogues of gonadotrophin releasing hormone for advanced prostatic cancer
    • Waxman J, Man A, Hendry WF et al. Importance of early tumour exacerbation in patients treated with long acting analogues of gonadotrophin releasing hormone for advanced prostatic cancer. Br. Med. J. 1985; 291: 1387-8.
    • (1985) Br. Med. J. , vol.291 , pp. 1387-1388
    • Waxman, J.1    Man, A.2    Hendry, W.F.3
  • 25
    • 0024340648 scopus 로고
    • Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide)
    • Kuhn JM, Billebaud T, Navratil H et al. Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide). N. Engl. J. Med. 1989; 321: 413-8.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 413-418
    • Kuhn, J.M.1    Billebaud, T.2    Navratil, H.3
  • 26
    • 77649179119 scopus 로고    scopus 로고
    • Does oral antiandrogen use before leuteinizing hormone-releasing hormone therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare?
    • Oh WK, Landrum MB, Lamont EB, McNeil BJ, Keating NL. Does oral antiandrogen use before leuteinizing hormone-releasing hormone therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare? Urology 2010; 75: 642-7.
    • (2010) Urology , vol.75 , pp. 642-647
    • Oh, W.K.1    Landrum, M.B.2    Lamont, E.B.3    McNeil, B.J.4    Keating, N.L.5
  • 27
    • 56649116179 scopus 로고    scopus 로고
    • The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer
    • Klotz L, Boccon-Gibod L, Shore ND et al. The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. BJU Int. 2008; 102: 1531-8.
    • (2008) BJU Int. , vol.102 , pp. 1531-1538
    • Klotz, L.1    Boccon-Gibod, L.2    Shore, N.D.3
  • 28
    • 84899476746 scopus 로고    scopus 로고
    • Long-term tolerability and efficacy of degarelix: 5-year results from a phase III extension trial with a 1-arm crossover from leuprolide to degarelix
    • Crawford ED, Shore ND, Moul JW et al. Long-term tolerability and efficacy of degarelix: 5-year results from a phase III extension trial with a 1-arm crossover from leuprolide to degarelix. Urology 2014; 83: 1122-8.
    • (2014) Urology , vol.83 , pp. 1122-1128
    • Crawford, E.D.1    Shore, N.D.2    Moul, J.W.3
  • 29
    • 0242440356 scopus 로고    scopus 로고
    • Bicalutamide monotherapy for early stage prostate cancer: an update
    • Iversen P. Bicalutamide monotherapy for early stage prostate cancer: an update. J. Urol. 2003; 170: S48-52.
    • (2003) J. Urol. , vol.170 , pp. S48-S52
    • Iversen, P.1
  • 30
    • 4344590998 scopus 로고    scopus 로고
    • Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition
    • Smith MR, Goode M, Zietman AL, McGovern FJ, Lee H, Finkelstein JS. Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition. J. Clin. Oncol. 2004; 22: 2546-53.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2546-2553
    • Smith, M.R.1    Goode, M.2    Zietman, A.L.3    McGovern, F.J.4    Lee, H.5    Finkelstein, J.S.6
  • 31
    • 2442581156 scopus 로고    scopus 로고
    • Bicalutamide 150 mg maintains bone mineral density during monotherapy for localized or locally advanced prostate cancer
    • Sieber PR, Keiller DL, Kahnoski RJ, Gallo J, McFadden S. Bicalutamide 150 mg maintains bone mineral density during monotherapy for localized or locally advanced prostate cancer. J. Urol. 2004; 171: 2272-6.
    • (2004) J. Urol. , vol.171 , pp. 2272-2276
    • Sieber, P.R.1    Keiller, D.L.2    Kahnoski, R.J.3    Gallo, J.4    McFadden, S.5
  • 32
    • 33845580082 scopus 로고    scopus 로고
    • Antiandrogens in the treatment of prostate cancer
    • Wirth MP, Hakenberg OW, Froehner M. Antiandrogens in the treatment of prostate cancer. Eur. Urol. 2007; 51: 306-13.
    • (2007) Eur. Urol. , vol.51 , pp. 306-313
    • Wirth, M.P.1    Hakenberg, O.W.2    Froehner, M.3
  • 33
    • 29044442028 scopus 로고    scopus 로고
    • Failure to achieve castration levels in patients using leuprolide acetate in locally advanced prostate cancer
    • Yri OE, Bjoro T, Fossa SD. Failure to achieve castration levels in patients using leuprolide acetate in locally advanced prostate cancer. Eur. Urol. 2006; 49: 54-8.
    • (2006) Eur. Urol. , vol.49 , pp. 54-58
    • Yri, O.E.1    Bjoro, T.2    Fossa, S.D.3
  • 34
    • 33746901635 scopus 로고    scopus 로고
    • Failure to maintain a suppressed level of serum testosterone during long-acting depot luteinizing hormone-releasing hormone agonist therapy in patients with advanced prostate cancer
    • Morote J, Esquena S, Abascal JM et al. Failure to maintain a suppressed level of serum testosterone during long-acting depot luteinizing hormone-releasing hormone agonist therapy in patients with advanced prostate cancer. Urol. Int. 2006; 77: 135-8.
    • (2006) Urol. Int. , vol.77 , pp. 135-138
    • Morote, J.1    Esquena, S.2    Abascal, J.M.3
  • 35
    • 84859529884 scopus 로고    scopus 로고
    • Lower testosterone levels with luteinizing hormone-releasing hormone agonist therapy than with surgical castration: new insights attained by mass spectrometry
    • van der Sluis TM, Bui HN, Meuleman EJ et al. Lower testosterone levels with luteinizing hormone-releasing hormone agonist therapy than with surgical castration: new insights attained by mass spectrometry. J. Urol. 2012; 187: 1601-6.
    • (2012) J. Urol. , vol.187 , pp. 1601-1606
    • van der Sluis, T.M.1    Bui, H.N.2    Meuleman, E.J.3
  • 36
    • 33749058933 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer
    • Keating NL, O'Malley AJ, Smith MR. Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J. Clin. Oncol. 2006; 24: 4448-56.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 4448-4456
    • Keating, N.L.1    O'Malley, A.J.2    Smith, M.R.3
  • 37
    • 84894442854 scopus 로고    scopus 로고
    • Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study
    • Jespersen CG, Nørgaard M, Borre M. Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study. Eur. Urol. 2014; 65: 704-9.
    • (2014) Eur. Urol. , vol.65 , pp. 704-709
    • Jespersen, C.G.1    Nørgaard, M.2    Borre, M.3
  • 38
    • 84986253537 scopus 로고    scopus 로고
    • Comparison of gonadotropin-releasing hormone agonists and orchiectomy: effects of androgen-deprivation therapy
    • Sun M, Choueiri TK, Hamnvik OR et al. Comparison of gonadotropin-releasing hormone agonists and orchiectomy: effects of androgen-deprivation therapy. JAMA Oncol. 2015; doi:10.1001/jamaoncol.2015.4917.
    • (2015) JAMA Oncol.
    • Sun, M.1    Choueiri, T.K.2    Hamnvik, O.R.3
  • 39
    • 77949653652 scopus 로고    scopus 로고
    • Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics
    • Tombal B, Miller K, Boccon-Gibod L et al. Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics. Eur. Urol. 2010; 57: 836-42.
    • (2010) Eur. Urol. , vol.57 , pp. 836-842
    • Tombal, B.1    Miller, K.2    Boccon-Gibod, L.3
  • 40
    • 84909956498 scopus 로고    scopus 로고
    • Disease control outcomes from analysis of pooled individual patient data from five comparative randomised clinical trials of degarelix versus luteinising hormone-releasing hormone agonists
    • Klotz L, Miller K, Crawford ED et al. Disease control outcomes from analysis of pooled individual patient data from five comparative randomised clinical trials of degarelix versus luteinising hormone-releasing hormone agonists. Eur. Urol. 2014; 66: 1101-8.
    • (2014) Eur. Urol. , vol.66 , pp. 1101-1108
    • Klotz, L.1    Miller, K.2    Crawford, E.D.3
  • 41
    • 84895058731 scopus 로고    scopus 로고
    • Cardiovascular morbidity associated with gonadotropin releasing hormone agonists and an antagonist
    • Albertsen PC, Klotz L, Tombal B, Grady J, Olesen TK, Nilsson J. Cardiovascular morbidity associated with gonadotropin releasing hormone agonists and an antagonist. Eur. Urol. 2014; 65: 565-73.
    • (2014) Eur. Urol. , vol.65 , pp. 565-573
    • Albertsen, P.C.1    Klotz, L.2    Tombal, B.3    Grady, J.4    Olesen, T.K.5    Nilsson, J.6
  • 42
    • 9444292850 scopus 로고    scopus 로고
    • Double-blind, randomized study of primary hormonal treatment of stage D2 prostate carcinoma: flutamide versus diethylstilbestrol
    • Chang A, Yeap B, Davis T et al. Double-blind, randomized study of primary hormonal treatment of stage D2 prostate carcinoma: flutamide versus diethylstilbestrol. J. Clin. Oncol. 1996; 14: 2250-7.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2250-2257
    • Chang, A.1    Yeap, B.2    Davis, T.3
  • 43
    • 0029882360 scopus 로고    scopus 로고
    • Randomised study of Casodex 50 MG monotherapy vs orchidectomy in the treatment of metastatic prostate cancer. The Scandinavian Casodex Cooperative Group
    • Iversen P, Tveter K, Varenhorst E. Randomised study of Casodex 50 MG monotherapy vs orchidectomy in the treatment of metastatic prostate cancer. The Scandinavian Casodex Cooperative Group. Scand. J. Urol. Nephrol. 1996; 30: 93-8.
    • (1996) Scand. J. Urol. Nephrol. , vol.30 , pp. 93-98
    • Iversen, P.1    Tveter, K.2    Varenhorst, E.3
  • 44
    • 0028886697 scopus 로고
    • Single-agent therapy with bicalutamide: a comparison with medical or surgical castration in the treatment of advanced prostate carcinoma
    • Chodak G, Sharifi R, Kasimis B, Block NL, Macramalla E, Kennealey GT. Single-agent therapy with bicalutamide: a comparison with medical or surgical castration in the treatment of advanced prostate carcinoma. Urology 1995; 46: 849-55.
    • (1995) Urology , vol.46 , pp. 849-855
    • Chodak, G.1    Sharifi, R.2    Kasimis, B.3    Block, N.L.4    Macramalla, E.5    Kennealey, G.T.6
  • 45
    • 0031798627 scopus 로고    scopus 로고
    • A randomised comparison of "Casodex" (bicalutamide) 150 mg monotherapy versus castration in the treatment of metastatic and locally advanced prostate cancer
    • Tyrrell CJ, Kaisary AV, Iversen P et al. A randomised comparison of "Casodex" (bicalutamide) 150 mg monotherapy versus castration in the treatment of metastatic and locally advanced prostate cancer. Eur. Urol. 1998; 33: 447-56.
    • (1998) Eur. Urol. , vol.33 , pp. 447-456
    • Tyrrell, C.J.1    Kaisary, A.V.2    Iversen, P.3
  • 46
    • 0029090784 scopus 로고
    • A randomised comparison of monotherapy with Casodex 50 mg daily and castration in the treatment of metastatic prostate carcinoma. Casodex Study Group
    • Kaisary AV, Tyrrell CJ, Beacock C, Lunglmayr G, Debruyne F. A randomised comparison of monotherapy with Casodex 50 mg daily and castration in the treatment of metastatic prostate carcinoma. Casodex Study Group. Eur. Urol. 1995; 28: 215-22.
    • (1995) Eur. Urol. , vol.28 , pp. 215-222
    • Kaisary, A.V.1    Tyrrell, C.J.2    Beacock, C.3    Lunglmayr, G.4    Debruyne, F.5
  • 47
    • 0032032068 scopus 로고    scopus 로고
    • Casodex (bicalutamide) 150-mg monotherapy compared with castration in patients with previously untreated nonmetastatic prostate cancer: results from two multicenter randomized trials at a median follow-up of 4 years
    • Iversen P, Tyrrell CJ, Kaisary AV et al. Casodex (bicalutamide) 150-mg monotherapy compared with castration in patients with previously untreated nonmetastatic prostate cancer: results from two multicenter randomized trials at a median follow-up of 4 years. Urology 1998; 51: 389-96.
    • (1998) Urology , vol.51 , pp. 389-396
    • Iversen, P.1    Tyrrell, C.J.2    Kaisary, A.V.3
  • 48
    • 0030726889 scopus 로고    scopus 로고
    • Flutamide versus orchidectomy in the treatment of metastatic prostate carcinoma
    • Boccon-Gibod L, Fournier G, Bottet P et al. Flutamide versus orchidectomy in the treatment of metastatic prostate carcinoma. Eur. Urol. 1997; 32: 391-5.
    • (1997) Eur. Urol. , vol.32 , pp. 391-395
    • Boccon-Gibod, L.1    Fournier, G.2    Bottet, P.3
  • 49
    • 84933670789 scopus 로고    scopus 로고
    • Non-steroidal antiandrogen monotherapy compared with luteinizing hormone-releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer: a Cochrane systematic review
    • Kunath F, Grobe HR, Rücker G et al. Non-steroidal antiandrogen monotherapy compared with luteinizing hormone-releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer: a Cochrane systematic review. BJU Int. 2015; 116: 30-6.
    • (2015) BJU Int. , vol.116 , pp. 30-36
    • Kunath, F.1    Grobe, H.R.2    Rücker, G.3
  • 50
    • 0020595290 scopus 로고
    • New hormonal therapy in prostate cancer: combined use of a pure antiandrogen and an LHRH agonist
    • Labrie F, Dupont A, Belanger A et al. New hormonal therapy in prostate cancer: combined use of a pure antiandrogen and an LHRH agonist. Horm. Res. 1983; 18: 18-27.
    • (1983) Horm. Res. , vol.18 , pp. 18-27
    • Labrie, F.1    Dupont, A.2    Belanger, A.3
  • 51
    • 0024324367 scopus 로고
    • A controlled trial of leuprolide with and without flutamide in prostatic carcinoma
    • Crawford ED, Eisenberger MA, McLeod DG et al. A controlled trial of leuprolide with and without flutamide in prostatic carcinoma. N. Engl. J. Med. 1989; 321: 419-24.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 419-424
    • Crawford, E.D.1    Eisenberger, M.A.2    McLeod, D.G.3
  • 52
    • 0032497522 scopus 로고    scopus 로고
    • Bilateral orchiectomy with or without flutamide for metastatic prostate cancer
    • Eisenberger MA, Blumenstein BA, Crawford ED et al. Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N. Engl. J. Med. 1998; 339: 1036-42.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1036-1042
    • Eisenberger, M.A.1    Blumenstein, B.A.2    Crawford, E.D.3
  • 54
    • 0034728828 scopus 로고    scopus 로고
    • Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials
    • Prostate Cancer Trialists' Collaborative Group. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Lancet 2000; 355: 1491-8.
    • (2000) Lancet , vol.355 , pp. 1491-1498
  • 55
    • 0037099723 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma
    • Samson DJ, Seidenfeld J, Schmitt B et al. Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma. Cancer 2002; 95: 361-76.
    • (2002) Cancer , vol.95 , pp. 361-376
    • Samson, D.J.1    Seidenfeld, J.2    Schmitt, B.3
  • 56
    • 0030824059 scopus 로고    scopus 로고
    • Clinical benefits of bicalutamide compared with flutamide in combined androgen blockade for patients with advanced prostatic carcinoma: final report of a double-blind, randomized, multicenter trial. Casodex Combination Study Group
    • Schellhammer PF, Sharifi R, Block NL et al. Clinical benefits of bicalutamide compared with flutamide in combined androgen blockade for patients with advanced prostatic carcinoma: final report of a double-blind, randomized, multicenter trial. Casodex Combination Study Group. Urology 1997; 50: 330-6.
    • (1997) Urology , vol.50 , pp. 330-336
    • Schellhammer, P.F.1    Sharifi, R.2    Block, N.L.3
  • 57
    • 2942739313 scopus 로고    scopus 로고
    • A re-assessment of the role of combined androgen blockade for advanced prostate cancer
    • Klotz L, Schellhammer P, Carroll K. A re-assessment of the role of combined androgen blockade for advanced prostate cancer. BJU Int. 2004; 93: 1177-82.
    • (2004) BJU Int. , vol.93 , pp. 1177-1182
    • Klotz, L.1    Schellhammer, P.2    Carroll, K.3
  • 58
    • 68149098902 scopus 로고    scopus 로고
    • Combined androgen blockade with bicalutamide for advanced prostate cancer: long-term follow-up of a phase 3, double-blind, randomized study for survival
    • Akaza H, Hinotsu S, Usami M et al. Combined androgen blockade with bicalutamide for advanced prostate cancer: long-term follow-up of a phase 3, double-blind, randomized study for survival. Cancer 2009; 115: 3437-45.
    • (2009) Cancer , vol.115 , pp. 3437-3445
    • Akaza, H.1    Hinotsu, S.2    Usami, M.3
  • 59
    • 16644372625 scopus 로고    scopus 로고
    • Timing and choice of androgen ablation
    • Kirk D. Timing and choice of androgen ablation. Prostate Cancer Prostatic Dis. 2004; 7: 217-22.
    • (2004) Prostate Cancer Prostatic Dis. , vol.7 , pp. 217-222
    • Kirk, D.1
  • 60
    • 7044269418 scopus 로고    scopus 로고
    • Immediate versus deferred hormonal treatment for patients with prostate cancer who are not suitable for curative local treatment: results of the randomized trial SAKK 08/88
    • Studer UE, Hauri D, Hanselmann S et al. Immediate versus deferred hormonal treatment for patients with prostate cancer who are not suitable for curative local treatment: results of the randomized trial SAKK 08/88. J. Clin. Oncol. 2004; 22: 4109-18.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4109-4118
    • Studer, U.E.1    Hauri, D.2    Hanselmann, S.3
  • 61
    • 84922268118 scopus 로고    scopus 로고
    • Differences in time to disease progression do not predict for cancer-specific survival in patients receiving immediate or deferred androgen-deprivation therapy for prostate cancer: final results of EORTC randomized trial 30891 with 12 years of follow-up
    • Studer UE, Whelan P, Wimpissinger F et al. Differences in time to disease progression do not predict for cancer-specific survival in patients receiving immediate or deferred androgen-deprivation therapy for prostate cancer: final results of EORTC randomized trial 30891 with 12 years of follow-up. Eur. Urol. 2014; 66: 829-38.
    • (2014) Eur. Urol. , vol.66 , pp. 829-838
    • Studer, U.E.1    Whelan, P.2    Wimpissinger, F.3
  • 62
    • 0027416692 scopus 로고
    • Effects of intermittent androgen suppression on androgen-dependent tumors. Apoptosis and serum prostate-specific antigen
    • Akakura K, Bruchovsky N, Goldenberg SL, Rennie PS, Buckley AR, Sullivan LD. Effects of intermittent androgen suppression on androgen-dependent tumors. Apoptosis and serum prostate-specific antigen. Cancer 1993; 71: 2782-90.
    • (1993) Cancer , vol.71 , pp. 2782-2790
    • Akakura, K.1    Bruchovsky, N.2    Goldenberg, S.L.3    Rennie, P.S.4    Buckley, A.R.5    Sullivan, L.D.6
  • 63
    • 0030152008 scopus 로고    scopus 로고
    • Intermittent androgen suppression delays progression to androgen-independent regulation of prostate-specific antigen gene in the LNCaP prostate tumour model
    • Sato N, Gleave ME, Bruchovsky N et al. Intermittent androgen suppression delays progression to androgen-independent regulation of prostate-specific antigen gene in the LNCaP prostate tumour model. J. Steroid Biochem. Mol. Biol. 1996; 58: 139-46.
    • (1996) J. Steroid Biochem. Mol. Biol. , vol.58 , pp. 139-146
    • Sato, N.1    Gleave, M.E.2    Bruchovsky, N.3
  • 64
    • 84875793215 scopus 로고    scopus 로고
    • Intermittent versus continuous androgen deprivation in prostate cancer
    • Hussain M, Tangen CM, Berry DL et al. Intermittent versus continuous androgen deprivation in prostate cancer. N. Engl. J. Med. 2013; 368: 1314-25.
    • (2013) N. Engl. J. Med. , vol.368 , pp. 1314-1325
    • Hussain, M.1    Tangen, C.M.2    Berry, D.L.3
  • 65
    • 84983488635 scopus 로고    scopus 로고
    • Intermittent vs continuous androgen deprivation therapy for prostate cancer: a systematic review and meta-analysis
    • Magnan S, Zarychanski R, Pilote L et al. Intermittent vs continuous androgen deprivation therapy for prostate cancer: a systematic review and meta-analysis. JAMA Oncol. 2015; 1: 1261-9.
    • (2015) JAMA Oncol. , vol.1 , pp. 1261-1269
    • Magnan, S.1    Zarychanski, R.2    Pilote, L.3
  • 66
    • 85010670269 scopus 로고    scopus 로고
    • Adverse health events following intermittent and continuous androgen deprivation in patients with metastatic prostate cancer
    • Hershman DL, Unger JM, Wright JD et al. Adverse health events following intermittent and continuous androgen deprivation in patients with metastatic prostate cancer. JAMA Oncol. 2015; doi:10.1001/jamaoncol.2015.4655.
    • (2015) JAMA Oncol.
    • Hershman, D.L.1    Unger, J.M.2    Wright, J.D.3
  • 67
    • 84904044669 scopus 로고    scopus 로고
    • Prime time for intermittent androgen suppression
    • Gleave M. Prime time for intermittent androgen suppression. Eur. Urol. 2014; 66: 240-2.
    • (2014) Eur. Urol. , vol.66 , pp. 240-242
    • Gleave, M.1
  • 68
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • Tannock IF, de Wit R, Berry WR et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. 2004; 351: 1502-12.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    de Wit, R.2    Berry, W.R.3
  • 69
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak DP, Tangen CM, Hussain MH et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N. Engl. J. Med. 2004; 351: 1513-20.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 70
    • 27644506552 scopus 로고    scopus 로고
    • Timing is everything: preclinical evidence supporting simultaneous rather than sequential chemohormonal therapy for prostate cancer
    • Eigl BJ, Eggener SE, Baybik J et al. Timing is everything: preclinical evidence supporting simultaneous rather than sequential chemohormonal therapy for prostate cancer. Clin. Cancer Res. 2005; 11: 4905-11.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 4905-4911
    • Eigl, B.J.1    Eggener, S.E.2    Baybik, J.3
  • 71
    • 84881078552 scopus 로고    scopus 로고
    • Interaction between docetaxel resistance and castration resistance in prostate cancer: implications of Twist1, YB-1, and androgen receptor
    • Shiota M, Kashiwagi E, Yokomizo A et al. Interaction between docetaxel resistance and castration resistance in prostate cancer: implications of Twist1, YB-1, and androgen receptor. Prostate 2013; 73: 1336-44.
    • (2013) Prostate , vol.73 , pp. 1336-1344
    • Shiota, M.1    Kashiwagi, E.2    Yokomizo, A.3
  • 72
    • 84873095322 scopus 로고    scopus 로고
    • Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial
    • Gravis G, Fizazi K, Joly F et al. Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial. Lancet Oncol. 2013; 14: 149-58.
    • (2013) Lancet Oncol. , vol.14 , pp. 149-158
    • Gravis, G.1    Fizazi, K.2    Joly, F.3
  • 73
    • 84939864061 scopus 로고    scopus 로고
    • Chemohormonal therapy in metastatic hormone-sensitive prostate cancer
    • Sweeney CJ, Chen YH, Carducci M et al. Chemohormonal therapy in metastatic hormone-sensitive prostate cancer. N. Engl. J. Med. 2015; 373: 737-46.
    • (2015) N. Engl. J. Med. , vol.373 , pp. 737-746
    • Sweeney, C.J.1    Chen, Y.H.2    Carducci, M.3
  • 74
    • 84961215473 scopus 로고    scopus 로고
    • Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial
    • James ND, Sydes MR, Clarke NW et al. Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet 2015; doi:10.1016/S0140-6736(15)01037-5.
    • (2015) Lancet
    • James, N.D.1    Sydes, M.R.2    Clarke, N.W.3
  • 75
    • 84941709876 scopus 로고    scopus 로고
    • Should docetaxel be standard of care for patients with metastatic hormone-sensitive prostate cancer? Pro and contra
    • Fizazi K, Jenkins C, Tannock IF. Should docetaxel be standard of care for patients with metastatic hormone-sensitive prostate cancer? Pro and contra Ann. Oncol. 2015; 26: 1660-7.
    • (2015) Ann. Oncol. , vol.26 , pp. 1660-1667
    • Fizazi, K.1    Jenkins, C.2    Tannock, I.F.3
  • 76
    • 84959261225 scopus 로고    scopus 로고
    • Addition of docetaxel to androgen deprivation therapy for patients with hormone-sensitive metastatic prostate cancer: a systematic review and meta-analysis
    • Tucci M, Bertaglia V, Vignani F et al. Addition of docetaxel to androgen deprivation therapy for patients with hormone-sensitive metastatic prostate cancer: a systematic review and meta-analysis. Eur. Urol. 2015; doi:10.1016/j.eururo.2015.09.013.
    • (2015) Eur. Urol.
    • Tucci, M.1    Bertaglia, V.2    Vignani, F.3
  • 77
    • 84958213594 scopus 로고    scopus 로고
    • Taxane chemotherapy for hormone-naïve prostate cancer with its expanding role as breakthrough strategy
    • Shiota M, Yokomizo A, Eto M. Taxane chemotherapy for hormone-naïve prostate cancer with its expanding role as breakthrough strategy. Front. Oncol. 2016; 5: 304.
    • (2016) Front. Oncol. , vol.5 , pp. 304
    • Shiota, M.1    Yokomizo, A.2    Eto, M.3
  • 78
    • 84959371082 scopus 로고    scopus 로고
    • Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
    • Vale CL, Burdett S, Rydzewska LH et al. Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data. Lancet Oncol. 2016; 17: 243-56.
    • (2016) Lancet Oncol. , vol.17 , pp. 243-256
    • Vale, C.L.1    Burdett, S.2    Rydzewska, L.H.3
  • 79
    • 84857629208 scopus 로고    scopus 로고
    • NCCN Guidelines
    • National Comprehensive Cancer Network. NCCN Guidelines. Available from URL: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp
  • 80
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
    • de Bono JS, Oudard S, Ozguroglu M et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 2010; 376: 1147-54.
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • de Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3
  • 81
    • 8444231965 scopus 로고    scopus 로고
    • The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer
    • Nishiyama T, Hashimoto Y, Takahashi K. The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer. Clin. Cancer Res. 2004; 10: 7121-6.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7121-7126
    • Nishiyama, T.1    Hashimoto, Y.2    Takahashi, K.3
  • 82
    • 84866770294 scopus 로고    scopus 로고
    • Increased survival with enzalutamide in prostate cancer after chemotherapy
    • Scher HI, Fizazi K, Saad F et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N. Engl. J. Med. 2012; 367: 1187-97.
    • (2012) N. Engl. J. Med. , vol.367 , pp. 1187-1197
    • Scher, H.I.1    Fizazi, K.2    Saad, F.3
  • 83
    • 84908450155 scopus 로고    scopus 로고
    • Enzalutamide in metastatic prostate cancer before chemotherapy
    • Beer TM, Armstrong AJ, Rathkopf DE et al. Enzalutamide in metastatic prostate cancer before chemotherapy. N. Engl. J. Med. 2014; 371: 424-33.
    • (2014) N. Engl. J. Med. , vol.371 , pp. 424-433
    • Beer, T.M.1    Armstrong, A.J.2    Rathkopf, D.E.3
  • 84
    • 84899969509 scopus 로고    scopus 로고
    • Enzalutamide monotherapy in hormone-naive prostate cancer: primary analysis of an open-label, single-arm, phase 2 study
    • Tombal B, Borre M, Rathenborg P et al. Enzalutamide monotherapy in hormone-naive prostate cancer: primary analysis of an open-label, single-arm, phase 2 study. Lancet Oncol. 2014; 15: 592-600.
    • (2014) Lancet Oncol. , vol.15 , pp. 592-600
    • Tombal, B.1    Borre, M.2    Rathenborg, P.3
  • 85
    • 84863230424 scopus 로고    scopus 로고
    • ARN-509: a novel antiandrogen for prostate cancer treatment
    • Clegg NJ, Wongvipat J, Joseph JD et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012; 72: 1494-503.
    • (2012) Cancer Res. , vol.72 , pp. 1494-1503
    • Clegg, N.J.1    Wongvipat, J.2    Joseph, J.D.3
  • 86
    • 79957443342 scopus 로고    scopus 로고
    • Abiraterone and increased survival in metastatic prostate cancer
    • de Bono JS, Logothetis CJ, Molina A et al. Abiraterone and increased survival in metastatic prostate cancer. N. Engl. J. Med. 2011; 364: 1995-2005.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 1995-2005
    • de Bono, J.S.1    Logothetis, C.J.2    Molina, A.3
  • 87
    • 84872078210 scopus 로고    scopus 로고
    • Abiraterone in metastatic prostate cancer without previous chemotherapy
    • Ryan CJ, Smith MR, de Bono JS et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. N. Engl. J. Med. 2013; 368: 138-48.
    • (2013) N. Engl. J. Med. , vol.368 , pp. 138-148
    • Ryan, C.J.1    Smith, M.R.2    de Bono, J.S.3
  • 88
    • 84925016549 scopus 로고    scopus 로고
    • Orteronel plus prednisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4): a double-blind, multicentre, phase 3, randomised, placebo-controlled trial
    • Saad F, Fizazi K, Jinga V et al. Orteronel plus prednisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4): a double-blind, multicentre, phase 3, randomised, placebo-controlled trial. Lancet Oncol. 2015; 16: 338-48.
    • (2015) Lancet Oncol. , vol.16 , pp. 338-348
    • Saad, F.1    Fizazi, K.2    Jinga, V.3
  • 89
    • 84925006635 scopus 로고    scopus 로고
    • Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5
    • Fizazi K, Jones R, Oudard S et al. Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5. J. Clin. Oncol. 2015; 33: 723-31.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 723-731
    • Fizazi, K.1    Jones, R.2    Oudard, S.3
  • 90
    • 32944481493 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone agonists and fracture risk: a claims-based cohort study of men with nonmetastatic prostate cancer
    • Smith MR, Lee WC, Brandman J, Wang Q, Botteman M, Pashos CL. Gonadotropin-releasing hormone agonists and fracture risk: a claims-based cohort study of men with nonmetastatic prostate cancer. J. Clin. Oncol. 2005; 23: 7897-903.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7897-7903
    • Smith, M.R.1    Lee, W.C.2    Brandman, J.3    Wang, Q.4    Botteman, M.5    Pashos, C.L.6
  • 91
    • 3242772959 scopus 로고    scopus 로고
    • Natural history of bone complications in men with prostate carcinoma initiating androgen deprivation therapy
    • Krupski TL, Smith MR, Lee WC et al. Natural history of bone complications in men with prostate carcinoma initiating androgen deprivation therapy. Cancer 2004; 101: 541-9.
    • (2004) Cancer , vol.101 , pp. 541-549
    • Krupski, T.L.1    Smith, M.R.2    Lee, W.C.3
  • 93
    • 0038075478 scopus 로고    scopus 로고
    • Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer
    • Smith MR, Eastham J, Gleason DM, Shasha D, Tchekmedyian S, Zinner N. Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. J. Urol. 2003; 169: 2008-12.
    • (2003) J. Urol. , vol.169 , pp. 2008-2012
    • Smith, M.R.1    Eastham, J.2    Gleason, D.M.3    Shasha, D.4    Tchekmedyian, S.5    Zinner, N.6
  • 94
    • 33947732766 scopus 로고    scopus 로고
    • Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: a randomized trial
    • Greenspan SL, Nelson JB, Trump DL, Resnick NM. Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: a randomized trial. Ann. Intern. Med. 2007; 146: 416-24.
    • (2007) Ann. Intern. Med. , vol.146 , pp. 416-424
    • Greenspan, S.L.1    Nelson, J.B.2    Trump, D.L.3    Resnick, N.M.4
  • 95
    • 84876048861 scopus 로고    scopus 로고
    • A phase 3, double-blind, randomised, parallel-group, placebo-controlled study of oral weekly alendronate for the prevention of androgen deprivation bone loss in nonmetastatic prostate cancer: the Cancer and Osteoporosis Research with Alendronate and Leuprolide (CORAL) study
    • Klotz LH, McNeill IY, Kebabdjian M, Zhang L, Chin JL; Canadian Urology Research Consortium. A phase 3, double-blind, randomised, parallel-group, placebo-controlled study of oral weekly alendronate for the prevention of androgen deprivation bone loss in nonmetastatic prostate cancer: the Cancer and Osteoporosis Research with Alendronate and Leuprolide (CORAL) study. Eur. Urol. 2013; 63: 927-35.
    • (2013) Eur. Urol. , vol.63 , pp. 927-935
    • Klotz, L.H.1    McNeill, I.Y.2    Kebabdjian, M.3    Zhang, L.4    Chin, J.L.5
  • 96
    • 69049105440 scopus 로고    scopus 로고
    • Denosumab in men receiving androgen-deprivation therapy for prostate cancer
    • Smith MR, Egerdie B, Hernández Toriz N et al. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N. Engl. J. Med. 2009; 361: 745-55.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 745-755
    • Smith, M.R.1    Egerdie, B.2    Hernández Toriz, N.3
  • 97
    • 71849114512 scopus 로고    scopus 로고
    • Effects of denosumab on bone mineral density in men receiving androgen deprivation therapy for prostate cancer
    • Smith MR, Saad F, Egerdie B et al. Effects of denosumab on bone mineral density in men receiving androgen deprivation therapy for prostate cancer. J. Urol. 2009; 182: 2670-5.
    • (2009) J. Urol. , vol.182 , pp. 2670-2675
    • Smith, M.R.1    Saad, F.2    Egerdie, B.3
  • 98
    • 2942518111 scopus 로고    scopus 로고
    • Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F, Gleason DM, Murray R et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J. Natl Cancer Inst. 2004; 96: 879-82.
    • (2004) J. Natl Cancer Inst. , vol.96 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 99
    • 79952360832 scopus 로고    scopus 로고
    • Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study
    • Fizazi K, Carducci M, Smith M et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet 2011; 377: 813-22.
    • (2011) Lancet , vol.377 , pp. 813-822
    • Fizazi, K.1    Carducci, M.2    Smith, M.3
  • 100
    • 84901944163 scopus 로고    scopus 로고
    • Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance)
    • Smith MR, Halabi S, Ryan CJ et al. Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance). J. Clin. Oncol. 2014; 32: 1143-50.
    • (2014) J. Clin. Oncol. , vol.32 , pp. 1143-1150
    • Smith, M.R.1    Halabi, S.2    Ryan, C.J.3
  • 101
    • 84880428467 scopus 로고    scopus 로고
    • Alpha emitter radium-223 and survival in metastatic prostate cancer
    • Parker C, Nilsson S, Heinrich D et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N. Engl. J. Med. 2013; 369: 213-23.
    • (2013) N. Engl. J. Med. , vol.369 , pp. 213-223
    • Parker, C.1    Nilsson, S.2    Heinrich, D.3
  • 102
    • 84901638475 scopus 로고    scopus 로고
    • Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial
    • Sartor O, Coleman R, Nilsson S et al. Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial. Lancet Oncol. 2014; 15: 738-46.
    • (2014) Lancet Oncol. , vol.15 , pp. 738-746
    • Sartor, O.1    Coleman, R.2    Nilsson, S.3
  • 103
    • 84908594586 scopus 로고    scopus 로고
    • Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial
    • Hoskin P, Sartor O, O'Sullivan JM et al. Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial. Lancet Oncol. 2014; 15: 1397-406.
    • (2014) Lancet Oncol. , vol.15 , pp. 1397-1406
    • Hoskin, P.1    Sartor, O.2    O'Sullivan, J.M.3
  • 104
    • 84933509575 scopus 로고    scopus 로고
    • SWOG S0925: a randomized phase II study of androgen deprivation combined with cixutumumab versus androgen deprivation alone in patients with new metastatic hormone-sensitive prostate cancer
    • Yu EY, Li H, Higano CS et al. SWOG S0925: a randomized phase II study of androgen deprivation combined with cixutumumab versus androgen deprivation alone in patients with new metastatic hormone-sensitive prostate cancer. J. Clin. Oncol. 2015; 33: 1601-8.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 1601-1608
    • Yu, E.Y.1    Li, H.2    Higano, C.S.3
  • 105
    • 84931840038 scopus 로고    scopus 로고
    • Final analysis of COMET-1: Cabozantinib (Cabo) versus prednisone (Pred) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) previously treated with docetaxel (D) and abiraterone (A) and/or enzalutamide (E)
    • Smith MR, de BJ, Sternberg CN et al. Final analysis of COMET-1: Cabozantinib (Cabo) versus prednisone (Pred) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) previously treated with docetaxel (D) and abiraterone (A) and/or enzalutamide (E). J. Clin. Oncol. 2015; 33 (Suppl 7): abstr 139.
    • (2015) J. Clin. Oncol. , vol.33
    • Smith, M.R.1    de, B.J.2    Sternberg, C.N.3
  • 106
    • 84947716857 scopus 로고    scopus 로고
    • Final analysis of COMET-2: Cabozantinib (Cabo) versus mitoxantrone/prednisone (MP) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with moderate to severe pain who were previously treated with docetaxel (D) and abiraterone (A) and/or enzalutamide (E)
    • Basch EM, Scholz MC, de BJ et al. Final analysis of COMET-2: Cabozantinib (Cabo) versus mitoxantrone/prednisone (MP) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with moderate to severe pain who were previously treated with docetaxel (D) and abiraterone (A) and/or enzalutamide (E). J. Clin. Oncol. 2015; 33 (Suppl 7): Abstr 141.
    • (2015) J. Clin. Oncol. , vol.33
    • Basch, E.M.1    Scholz, M.C.2    de, B.J.3
  • 107
    • 74449089780 scopus 로고    scopus 로고
    • Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression
    • Shiota M, Yokomizo A, Tada Y et al. Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression. Oncogene 2010; 29: 237-50.
    • (2010) Oncogene , vol.29 , pp. 237-250
    • Shiota, M.1    Yokomizo, A.2    Tada, Y.3
  • 108
    • 80052270884 scopus 로고    scopus 로고
    • Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer
    • Shiota M, Yokomizo A, Naito S. Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer. Free Radic. Biol. Med. 2011; 51: 1320-8.
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 1320-1328
    • Shiota, M.1    Yokomizo, A.2    Naito, S.3
  • 109
    • 84855577580 scopus 로고    scopus 로고
    • Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer
    • Shiota M, Song Y, Takeuchi A et al. Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer. J. Urol. 2012; 187: 707-14.
    • (2012) J. Urol. , vol.187 , pp. 707-714
    • Shiota, M.1    Song, Y.2    Takeuchi, A.3
  • 110
    • 84855709289 scopus 로고    scopus 로고
    • SOD mimetics: a novel class of androgen receptor inhibitors that suppresses castration-resistant growth of prostate cancer
    • Thomas R, Sharifi N. SOD mimetics: a novel class of androgen receptor inhibitors that suppresses castration-resistant growth of prostate cancer. Mol. Cancer Ther. 2012; 11: 87-97.
    • (2012) Mol. Cancer Ther. , vol.11 , pp. 87-97
    • Thomas, R.1    Sharifi, N.2


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