High serum testosterone levels during postpartum period are associated with postpartum depression

Asian Journal of Psychiatry

Volumn 17, Issue , 2015, Pages 85-88

  Aswathi, A ^a   Rajendiren, Soundravally ^a   Nimesh, Archana ^a   Philip, R Ravi ^a   Kattimani, Shivanand ^a   Jayalakshmi, D ^a   Ananthanarayanan, P H ^a   Dhiman, Pooja ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Etiology; Postpartum mood disorders; Sex steroid hormones; Testosterone

Indexed keywords

ESTRADIOL; PROGESTERONE; TESTOSTERONE;

ADULT; AREA UNDER THE CURVE; BLOOD; CROSS-SECTIONAL STUDY; DEPRESSION, POSTPARTUM; FEMALE; HUMAN; INDIA; PREDICTIVE VALUE; PSYCHOLOGY; PUERPERIUM; RECEIVER OPERATING CHARACTERISTIC; TIME FACTOR;

ADULT; AREA UNDER CURVE; CROSS-SECTIONAL STUDIES; DEPRESSION, POSTPARTUM; ESTRADIOL; FEMALE; HUMANS; INDIA; POSTPARTUM PERIOD; PREDICTIVE VALUE OF TESTS; PROGESTERONE; ROC CURVE; TESTOSTERONE; TIME FACTORS;

EID: 84963788795     PISSN: 18762018     EISSN: 18762026     Source Type: Journal    
DOI: 10.1016/j.ajp.2015.08.008     Document Type: Article

References (24)

1. Abou-Saleh M.T., Ghubash R., Karim L., Krymski M., Bhai I. Hormonal aspects of post-partum depression. Psychoneuroendocrinology 1998, 23:465-475.
2. Adewuya A.O., Ola B.A., Dada A.O., Fasoto O.O. Validation of the Edinburgh Postnatal Depression Scale as a screening tool for depression in late pregnancy among Nigerian women. J. Psychosom. Obstet. Gynaecol. 2006, 27:267-272.
3. Beck C.T. Maternal depression and child behaviour problems: a meta-analysis. J. Adv. Nurs. 1999, 29:623-629.
4. Buckwalter J.G., Stanczyk F.Z., McCleary C.A., Bluestein B.W., Buckwalter D.K., Rankin K.P. Pregnancy, the postpartum, and steroid hormones: effects on cognition and mood. Psychoneuroendocrinology 1999, 24(1):69-84.
5. Cox J.L., Holden J.M., Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br. J. Psychiatry 1987, 150:782-786.
6. Diagnostic and Statistical Manual of Mental Disorders (DSM-5) 2013, American Psychiatric Association, Arlington, VA. 5th ed.
7. Dubey C., Gupta N., Bhasin S., Muthal R.A., Arora R. Prevalence and associated risk factors for postpartum depression in women attending a tertiary hospital, Delhi, India. Int. J. Soc. Psychiatry 2012, 58(6):577-580.
8. Feksi A., Harris B., Walker R.F., Riad-Fahmy D., Newcombe R.G. 'Maternity blues' and hormone levels in saliva. J. Affect. Disord. 1984, 6:351-355.
9. Flores D.L., Hendrick V. Etiology and treatment of postpartum depression. Curr. Psychiatry Rep. 2002, 4:461-546.
10. Gavin N.I., Gaynes B.N., Lohr K.N., Meltzer-Brody S., Gartlehner G., Swinson T. Perinatal depression: a systematic review of prevalence and incidence. Obstet. Gynecol. 2005, 106(5, Part 1):1071-1083.
11. Harris B., Lovett L., Newcombe R.G., Read G.F., Walker R., Riad-Fahmy D. Maternity blues and major endocrine changes: cardiff puerperal mood and hormone study II. Br. Med. J. 1994, 308(6934):949-953.
12. Hines M. Sex steroids and human behavior: prenatal androgen exposure and sex-typical play behavior in children. Ann. N. Y. Acad. Sci. 2003, 1007:272-282.
13. Hohlagschwandtner M., Husslein P., Klier C., Ulm B. Correlation between serum testosterone levels and peripartal mood states. Acta Obstet. Gynecol. Scand. 2001, 80(4):326-330.
14. Martin C.K., Silverstein R. Suffering in silence: a qualitative meta data-analysis of PPD. J. Marital Fam. Ther. 2009, 35:145-158.
15. Miller L.J. Postpartum depression. J. Am. Med. Assoc. 2002, 287:762-765.
16. Numakawa T., Richards M., Nakajima S., Adachi N., Furuta M., Odaka H., Kunugi H. The role of brain-derived neurotrophic factor in comorbid depression: possible linkage with steroid hormones, cytokines, and nutrition. Front. Psychiatry 2014, 26(5):136.
17. O'hara M.W., Swain A.M. Rates and risk of postpartum depression-a meta-analysis. Int. Rev. Psychiatry 1996, 8:37-54.
18. O'Hara M.W., Schlechte J.A., Lewis D.A., Wright E.J. Prospective study of postpartum blues: biologic and psychosocial factors. Arch. Gen. Psychiatry 1991, 48:801-806.
19. Paulson J.F., Bazemore S.D. Prenatal and postpartum depression in fathers and its association with maternal depression: a meta-analysis. J. Am. Med. Assoc. 2010, 303:1961-1969.
20. Romeo E., Strohle A., Spalletta G., di M.F., Hermann B., Holsboer F. Effects of antidepressant treatment on neuroactive steroids in major depression. Am. J. Psychiatry 1998, 155(7):910-913.
21. Sarrel P.M. Psychosexual effects of menopause: role of androgens. Am. J. Obstet. Gynecol. 1999, 180:S319-S324.
22. The National Women's Health Information Center US Department of Health and Human Services 2002.
23. Tronick E., Reck C. Infants of depressed mothers. Harv. Rev. Psychiatry 2009, 17:147-156.
24. Weiner C.L., Primeau M., Ehrmann D.A. Androgens and mood dysfunction in women: comparison of women with polycystic ovarian syndrome to healthy controls. Psychosom. Med. 2004, 66(3):356-362.