Effect of morinda citrifolia (Noni) fruit juice on high fat diet induced dyslipidemia in rats

Journal of Clinical and Diagnostic Research

Volumn 10, Issue 4, 2016, Pages FF06-FF10

  Shoeb, Ahsan ^a   Alwar, M C ^a   Shenoy, Preethi J ^a   Gokul, P ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

Author keywords

High density lipoprotein; Hypolipidemic activity; Low density lipoprotein; Noni fruit; Plasma lipids; Total cholesterol; Very low density lipoprot

Indexed keywords

ATORVASTATIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MORINDA CITRIFOLIA EXTRACT; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE CONTROL; DYSLIPIDEMIA; FRUIT JUICE; HISTOPATHOLOGY; LIPID BLOOD LEVEL; LIPID DIET; MALE; MORINDA CITRIFOLIA; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 84963787382     PISSN: 2249782X     EISSN: 0973709X     Source Type: Journal    
DOI: 10.7860/JCDR/2016/17900.7650     Document Type: Article

References (26)

1. Rader DJ, Hobbs HH. Disorders of lipoprotein metabolism. In: Fauci AS, Kasper DL, Longo DL, Braunwald E, Hauser SL, Jamsson JL, editors. Harrisons’s principles of internal medicine. 17th ed. New York: McGraw-Hill; 2007.p. 2416-29.
2. Gaudio G, Guasti L, Schizzartto A, Bossi P, Masnaghetti S, Cosini I, et al. Correlation between pulse pressure and LDL-cholesterol in patients with resistant hypertension. Am J Hypertens. 2001;14: 246A-47A.
3. Bersot PB. Drug therapy for hypercholesterolemia and dyslipidemia. In: Burton LL, editor. Goodman & Gillman’s The pharmacological basis of therapeutics. 12th ed. New Delhi: McGraw Hill; 2011.p. 877-908.
4. Bhardwaj SS, Chalasina N. Lipid lowering agents that cause drug-induced hepatotoxicity. Clin Liver Dis. 2007;11(3):1-18.
5. Ying WM, West BJ, Jensen CJ, Nowicki D, Chen SU, Paul AK, et al. Morinda citrofolia (Noni): A literature review and recent advances in noni research. Acta Pharmacol Sin. 2002;23(12):1127-41.
6. Wang MY, Nowicki D, Anderson G, Jenson J, West B. Liver protective effects of Morinda citrifolia (Noni). Plant Foods Hum Nutr. 2008;63:59–63.
7. McClatchey W. From Polynesian healers to health food stores: Changing [7]perspectives of Morinda citrifolia (Rubiaceae). Integr Cancer Ther. 2002;1(2): 110-20.
8. Mckoy MG, Thomas EA, Simon OR, Preliminary investigations of anti-inflammatory properties of an aqueous extract from Morinda citrifolia (Noni). Proc West Pharmacol Soc. 2002;45:76-78.
9. Ma D, West BJ, Su CX, Gao J, Liu T, Liu YW. Evaluation of ergogenic potential of noni juice. Photother Res. 2007;21:1100-01.
10. About our Noni. H & M Roberts Enterprises. Available from: http://www.nonihealingjuice.com. (Accessed on 19 Aug 2009).
11. Illness and diseases noni known to have cured. Available from: http://www.sarinoni.com/medical.html. (Accessed on 19 Aug 2009).
12. Palu FK, West BJ, Jensen CJ, Zhou BN. Morinda citrifolia L. Noni has Cholesterol Lowering Potential. Proceedings of the 47th Annual Meeting of Society for Economic Botany; 2006 June 5-9; Chiang Mai,Thailand. Honululu: The Society for Economic Botany, Inc; 2006. (Abstract) Available from: www.econbot.org/_organization_/07_annual_meetings/meetings_by_year/2006/pdfs/SEB2006%20Program.pdf (Accessed on 7th Aug 2009).
13. Wang MY, Henley E, Nolting J, et al. Noni juice may lower total cholesterol and triglycerides in adult smokers. Abstract P78 (EPI) presented at on 03-02-2006 American Heart Association’s 46th Annual Conference on Cardiovascular Disease Epidemiology and Prevention. http://www.americanheart.org/ presenter.jhtml; jsessionid (Accessed on March 2007).
14. Kanodia L, Borgohain M, Das S. Effect of fruit extract of Fragaria vesca L. on experimentally induced inflammatory bowel disease in albino rats. Indian J Pharmacol. 2011;43:18-21.
15. Organization for Economic Cooperation and Development (OECD). OECD Guidelines for Testing of Chemicals. France: OECD Publishing; 2006 July 11. p. 1-27. Section 4, Health Effects: Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure. [last adopted on 2006 Mar 23]. Available from: http://browse.oecdbookshop.org/oecd/pdfs/free/9740701e.pdf [last cited on 2011 Jun 09].
16. Kumar V, Singh S, Khanna AK, Khan MM, Chander R, Mahdi F, et al. Hypolipidemic activity of Anthocephalus indicus (kadam) in hyperlipidemic rats. Med Chem Res. 2008;17:152-58.
17. Nevin KG, Rajamohan T. Wet and dry extraction of coconut oil: impact on lipid metabolic and antioxidant status in cholesterol co-administered rats. Can J Physiol Pharmacol. 2009;87(8):610-16.
18. Stucchi AF, Hennessy LK, Vespa DB, Weiner EJ, Osada J, Ordovas JM, et al. Effect of corn and coconut oil-containing diets with and without cholesterol on high density lipoprotein apoprotein A-I metabolism and hepatic apoprotein A-I mRNA Levels in Cebus monkeys. Arterioscler Thromb Vasc Biol. 1991;11:1719-29.
19. Katan MB, Zock PL, Mensink RP. Effects of fats and fatty acids on blood lipids in humans: an overview. Am J Clin Nutr. 1994;60:1017S-22S.
20. Nevin KG, Rajamohan T. Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clin Biochem. 2004;37(9):830-35.
21. Mandukhail SR, Aziz N, Gilani AH. Studies on antidyslipidemic effects of Morinda citrifolia (Noni) fruit, leaves and root extracts. Lipids Health Dis. 2010;9:88.
22. Wilson PW, Abbott RD, Castelli WP. High density lipoprotein cholesterol and mortality. The Framingham Heart Study. Atheroscler Thromb Vasc Biol. 1988; 8:737-41.
23. Palu FK, West BJ, Jensen CJ, Zhou BN. Morinda citrifolia L. Noni has Chole sterol Lowering Potential. Proceedings of the 47th Annual Meeting of Society for Economic Botany; 2006 June 5-9; Chiang Mai,Thailand. Honululu: The Society for Economic Botany, Inc; 2006. (Abstract) Available from: www.econbot.org/_organization_/07_annual_meetings/meetings_by_year/2006/pdfs/SEB2006%20Program.pdf (Accessed on 7th Aug 2009).
24. Nandhasri P, Pawa KK, Kaewtubtim J, Jeamchanya C, Jansom C, Sattaponpun C. Nutraceutical properties of Thai “Yor” Morinda citrifolia and “Noni” juice extract. Songklanakarin J Sci Technol. 2005;27(2):579-86.
25. Salleh MN, Runnie I, Roach PD, Mohamed S, Abeywardena MY. Inhibition of low-density lipoprotein oxidation and up-regulation of low-density lipoprotein receptor in HepG2 cells by tropical plant extracts. J Agric Food Chem. 2002;50(13): 3693-97.
26. Sasnan GS, Hanani E, Kristianto J. Effect of Morinda citrifolia fruit extract capsule on total cholesterol levels in patients with hypercholesterolemia. Tropical Journal of Pharmaceutical Research. 2014;13(8):1319-26.