Severely impaired microvascular reactivity in diabetic patients with an acute coronary syndrome

Cardiovascular Diabetology

Volumn 15, Issue 1, 2016, Pages

  Östlund Papadogeorgos, Nikolaos ^a   Jörneskog, Gun ^a   Bengtsson, Mattias ^a   Kahan, Thomas ^a   Kalani, Majid ^a  

^a DANDERYD HOSPITAL   (Sweden)

Author keywords

Acute coronary syndrome; Coronary artery disease; Diabetes mellitus; Laser Doppler fluxmetry; Microvascular reactivity

Indexed keywords

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETIC MICROANGIOPATHY; DIABETIC PATIENT; DISEASE SEVERITY; FEMALE; HUMAN; LASER DOPPLER FLOWMETRY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; SKIN BLOOD VESSEL; BLOOD; COMPLICATION; CORONARY ANGIOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; MICROCIRCULATION; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SKIN; VASCULARIZATION; VERY ELDERLY;

GLUCOSE BLOOD LEVEL;

ACUTE CORONARY SYNDROME; ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; MIDDLE AGED; SKIN;

EID: 84963739352     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-016-0385-6     Document Type: Article

References (40)

1. Ijzerman RG, de Jongh RT, Beijk MA, van Weissenbruch MM, de Delemarre-van HA, Serné EH, Stehouwer CD. Individuals at increased coronary heart disease risk are characterised by an impaired microvascular function in skin. Eur J Clin Invest. 2003;33:536-42.
2. Strain WD, Chaturvedi N, Hughes A, Nihoyannopoulos P, Bulpitt CJ, Rajkumar C, Shore AC. Associations between cardiac target organ damage and microvascular dysfunction: the role of blood pressure. J Hypertens. 2010;28:952-8.
3. Gerstein HC, Mann JF, Yi Q, Zinman B, Dinneen SF, Hoogwerf B, Hallé JP, Young J, Rashkow A, Joyce C, Nawaz S, Yusuf S. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA. 2001;286:421-6.
4. Ljungman S, Wikstrand J, Hartford M, Berglund G. Urinary albumin excretion: a predictor of risk of cardiovascular disease. A prospective 10-year follow-up of middle-aged nondiabetic normal and hypertensive men. Am J Hypertens. 1996;9:770-8.
5. Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR, Lerman A. Longterm follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation. 2000;101:948-54.
6. Bonetti PO, Lerman LO, Lerman A. Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol. 2003;23:168-75.
7. Widlansky ME, Gokce N, Keaney JF, Vita JA. The clinical implications of endothelial dysfunction. J Am Coll Cardiol. 2003;42:1149-60.
8. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000;101:1899-906.
9. Seino Y. Cardiac function and peripheral circulatory adjustments in patients with acute myocardial infarction. Observations during the early stage of AMI. Jpn Heart J. 1983;24:515-28.
10. Skagen K, Henriksen O, Amtorp O, Fog-Moller F, Lam H. Local regulation of blood flow in subcutaneous tissue in patients with acute myocardial infarction. Clin Sci. 1981;60:157-64.
11. Strain WD, Hughes AD, Mayet J, Wright AR, Kooner J, Chaturvedi N, Shore AC. Attenuation of microvascular function in those with cardiovascular disease is similar in patients of Indian Asian and European descent. BMC Cardiovasc Disord. 2010;15(10):3.
12. Azman-Juvan K, Bernjak A, Urbancic-Rovan V, Stefanovska A, Stajer D. Skin blood flow and its oscillatory components in patients with acute myocardial infarction. J Vasc Res. 2008;45:164-72.
13. Strain WD, Hughes AD, Mayet J, Wright AR, Kooner J, Chaturvedi N, Shore AC. Attenuated systemic microvascular function in men with coronary artery disease is associated with angina but not explained by atherosclerosis. Microcirculation. 2013;20:670-7.
14. Agarwal SC, Allen J, Murray A, Purcell IF. Laser Doppler assessment of dermal circulatory changes in people with coronary artery disease. Microvasc Res. 2012;84:55-9.
15. Tibirica E, Souza EG, De Lorenzo A, Oliveira GM. Reduced systemic microvascular density and reactivity in individuals with early onset coronary artery disease. Microvasc Res. 2015;97:105-8.
16. Souza EG, De Lorenzo A, Huguenot G, Oliveira GM, Tibirica E. Impairment of systemic microvascular endothelial and smooth muscle function in individuals with early-onset coronary artery disease: studies with laser speckle contrast imaging. Coron Artery Dis. 2014;25(1):23-8.
17. Ovadia-Blechman Z, Avrahami I, Weizman-Shammai E, Sharir T, Eldar M, Chouraqui P. Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia. Biomed Pharmacother. 2015;74:83-8.
18. Trifunovic D, Stankovic S, Sobic-Saranovic D, Marinkovic J, Petrovic M, Orlic D, Beleslin B, Banovic M, Vujisic-Tesic B, Petrovic M, Nedeljkovic I, Stepanovic J, Djordjevic-Dikic A, Tesic M, Djukanovic N, Petrovic O, Vasovic O, Nestorovic E, Kostic J, Ristic A, Ostojic M. Acute insulin resistance in ST-segment elevation myocardial infarction in non-diabetic patients is associated with incomplete myocardial reperfusion and impaired coronary microcirculatory function. Cardiovasc Diabetol. 2014;13:73.
19. Norhammar A, Tenerz Å, Nilsson G, Hamsten A, Efendic S, Rydén L, Malmberg K. Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study. Lancet. 2002;359:2140-4.
20. Kuhl J, Jörneskog G, Wemminger M, Bengtsson M, Lundman P, Kalani M. Long-term clinical outcome in patients with acute coronary syndrome and dysglycaemia. Cardiovasc Diabetol. 2015;14(1):120.
21. Jarnert C, Kalani M, Rydén L, Böhm F. Strict glycaemic control improves skin microcirculation in patients with type 2 diabetes: a report from the diabetes mellitus and diastolic dysfunction (DADD) study. Diab Vasc Dis Res. 2012;9(4):287-95.
22. Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Eur Heart J. 2000; 21(18):1502-13.
23. Report of the Expert Committee on the diagnosis and classification of diabetes mellitus. Diabetes care. 1997; 20(7):1183-97.
24. Fagrell B, Jörneskog G, Intaglietta M. Disturbed microvascular reactivity and shunting-a major cause for diabetic complications. Vasc Med. 1999;4:125-7.
25. Tooke JE. Possible pathophysiological mechanisms for diabetic angiopathy in type 2 diabetes. J Diabetes Complications. 2000;14:197-200.
26. Cheung N, Wang JJ, Rogers SL, et al. Diabetic retinopathy and risk of heart failure. J Am Coll Cardiol. 2008;51:1573-8.
27. Papadogeorgos ÖN, Bengtsson M, Kalani M. Selective endothelin A-receptor blockade attenuates coronary microvascular dysfunction after coronary stenting in patients with type 2 diabetes. Vasc Health Risk Manag. 2009;5:893-9.
28. Verouden NJW, Haeck JDE, Kuijt WJ, Meuwissen M, Koch KT, Henriques JPS, Baan J, Vis MM, Piek JJ, Tijssen JGP, Winter RJ. Clinical and angiographic predictors of ST-segment recovery after primary percutaneous coronary intervention. Am J Cardiol. 2010;105:1692-7.
29. Hokama JY, Ritter LS, Davis-Gorman G, Cimetta AD, Copeland JG, McDonagh PF. Diabetes enhances leukocyte accumulation in the coronary microcirculation early in reperfusion following ischemia. J Diabetes Complication. 2000;14:96-107.
30. Shechter M, Merz CN, Paul-Labrador MJ, Kaul S. Blood glucose and plateletdependent thrombosis in patients with coronary artery disease. J Am Coll Cardiol. 2000;35:300-7.
31. Sakuma T, Leong-Poi H, Fisher NG, Goodman NC, Kaul S. Further insights into the no-reflow phenomenon after primary angioplasty in acute myocardial infarction: the role of microthromboemboli. J Am Soc Echocardiogr. 2003;16:15-21.
32. Settergren M, Pernow J, Brismar K, Jörneskog G, Kalani M. Endothelin-A receptor blockade increases nutritive skin capillary circulation in patients with type 2 diabetes and microangiopathy. J Vasc Res. 2008;45:295-302.
33. Jörneskog G, Brismar K, Fagrell B. Skin capillary circulation is more impaired in the toes of diabetic than non-diabetic patients with peripheral vascular disease. Diabet Med. 1995;12:36-41.
34. Settergren M, Böhm F, Rydén L, Pernow J, Kalani M. Lipid lowering versus pleiotropic effects of statins on skin microvascular function in patients with dysglycaemia and coronary artery disease. J Intern Med. 2009;266:492-8.
35. Jarnert C, Kalani M, Rydén L, Böhm F. Strict glycaemic control improves skin microcirculation in patients with type 2 diabetes: a report from the diabetes mellitus and diastolic dysfunction (DADD) study. Diab Vasc Dis Res. 2012;9(4):287-95.
36. Strain WD, Chaturvedi N, Leggetter S, Nihoyannopoulos P, Rajkumar C, Bulpitt CJ, Shore AC. Ethnic differences in skin microvascular function and their relation to cardiac target- organ damage. J Hypertens. 2005;23:133-40.
37. Gooding KM, Hannemann MM, Tooke JE, Clough GF, Shore AC. Maximum skin hyperaemia induced by local heating: possible mechanisms. J Vasc Res. 2006;43:270-7.
38. Roustit M, Blaise S, Millet C, Cracowski JL. Reproducibility and methodological issues of skin post-occlusive and thermal hyperemia assessed by single-point laser Doppler flowmetry. Microvasc Res. 2010;79(2):102-8.
39. Millet C, Roustit M, Blaise S, Cracowski JL. Comparison between laser speckle contrast imaging and laser Doppler imaging to assess skin blood flow in humans. Microvasc Res. 2011;82(2):147-51.
40. Tibiriçá E, Matheus AS, Nunes B, Sperandei S, Gomes MB. Repeatability of the evaluation of systemic microvascular endothelial function using laser doppler perfusion monitoring: clinical and statistical implications. Clinics. 2011;66(4):599-605.