Dystonia, lower limb stiffness, and upward gaze palsy in a patient with IgLON5 antibodies

Movement Disorders

Volumn 31, Issue 5, 2016, Pages 762-764

  Brüggemann, Norbert ^a   Wandinger, Klaus Peter ^a,b   Gaig, Carles ^c,d   Sprenger, Andreas ^a   Junghanns, Klaus ^a   Helmchen, Christoph ^a   Münchau, Alexander ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

IGLON5 ANTIBODY; IMMUNOGLOBULIN ANTIBODY; UNCLASSIFIED DRUG; ANTIBODY; IGLON5 PROTEIN, HUMAN; NERVE CELL ADHESION MOLECULE;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; CASE REPORT; DYSTONIA; GAZE PARALYSIS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LOWER LIMB; MALE; MIDDLE AGED; MUSCULOSKELETAL STIFFNESS; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPASTICITY; VIDEOOCULOGRAPHY; ANIMAL; BRAIN; DYSTONIC DISORDER; EYE FIXATION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PROCEDURES; RAT;

ANIMALS; ANTIBODIES; BRAIN; CELL ADHESION MOLECULES, NEURONAL; DYSTONIA; DYSTONIC DISORDERS; FIXATION, OCULAR; HUMANS; IMMUNOHISTOCHEMISTRY; LOWER EXTREMITY; MALE; MIDDLE AGED; RATS;

EID: 84963682498     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26608     Document Type: Article

References (4)

1. Czirr E, Wyss-Coray T. The immunology of neurodegeneration. J Clin Invest 2012;122:1156-1163.
2. Sabater L, Gaig C, Gelpi E, et al. A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study. Lancet Neurol 2014;13:575-586.
3. Hogl B, Heidbreder A, Santamaria J, Graus F, Poewe W. IgLON5 autoimmunity and abnormal behaviours during sleep. Lancet 2015;385:1590.
4. Simabukuro MM, Sabater L, Adoni T, et al. Sleep disorder, chorea, and dementia associated with IgLON5 antibodies. Neurol Neuroimmunol Neuroinflamm 2015;2:e136.