Sleep disorder, chorea, and dementia associated with IgLON5 antibodies

Neurology: Neuroimmunology and NeuroInflammation

Volumn 2, Issue 4, 2015, Pages 1-2

  Simabukuro, Mateus M ^a   Sabater, Lidia ^b   Adoni, Tarso ^a   Cury, Rubens Gisbert ^a,c   Haddad, Mônica Santoro ^a   Moreira, Camila Hobi ^a   Oliveira, Luana ^a   Boaventura, Mateus ^a   Alves, Rosana Cardoso ^a   Soster, Leticia Azevedo ^a   Nitrini, Ricardo ^a   Gaig, Carles ^a   Santamaria, Joan ^c   Dalmau, Josep ^b,d,e   Graus, Francesc ^b,c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HALOPERIDOL; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; IMMUNOGLOBULIN; RITUXIMAB;

AGED; BRAIN DISEASE; CASE REPORT; CEREBROSPINAL FLUID EXAMINATION; CHOREA; DEMENTIA; DISEASE ASSOCIATION; FEMALE; HAPLOTYPE; HUMAN; HUNTINGTON CHOREA; IGLON5 ENCEPHALOPATHY; MINI MENTAL STATE EXAMINATION; MUSCLE HYPOTONIA; NEUROPSYCHOLOGICAL TEST; PLEOCYTOSIS; PRIORITY JOURNAL; SHORT SURVEY; SLEEP DISORDER;

EID: 84976879585     PISSN: None     EISSN: 23327812     Source Type: Journal    
DOI: 10.1212/NXI.0000000000000136     Document Type: Short Survey

References (7)

1. Högl B, Heidbreder A, Santamaria J, Graus F, Poewe W. IgLON5 autoimmunity and abnormal behaviours during sleep. Lancet 2015; 385:1590.
2. Sabater L, Gaig C, Gelpi E, et al. A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study. Lancet Neurol 2014; 13:575-586.
3. Lugaresi E, Provini F. Agrypnia excitata: clinical features and pathophysiological implications. Sleep Med Rev 2001; 5:313-332.
4. Gaig C, Iranzo A, Santamarí J, Dalmau J, Graus F. Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?-Authors' reply. Lancet Neurol 2014; 13: 864-865.
5. Spillantini MG, Goedert M. Tau pathology and neurodegeneration. Lancet Neurol 2013; 12:609-622.
6. Ludolph AC, Kassubek J, Landwehrmeyer BG, et al.; Reisensburg Working Group for Tauopathies with Parkinsonism. Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options. Eur J Neurol 2009; 16:297-309.
7. Fahn S, Jankovic J, Hallett M. Principles and Practice of Movement Disorders: Expert Consult, 2nd ed. Edinburgh, New York: Saunders; 2011.