메뉴 건너뛰기




Volumn 21, Issue 2, 2016, Pages

Coumarins as potential antioxidant agents complemented with suggested mechanisms and approved by molecular modeling studies

Author keywords

Antioxidant activity; Coumarin; DPPH; H2O2

Indexed keywords

1,1-DIPHENYL-2-PICRYLHYDRAZYL; ANTIOXIDANT; ASCORBIC ACID; BIPHENYL DERIVATIVE; COUMARIN DERIVATIVE; HYDROGEN PEROXIDE; PICRIC ACID;

EID: 84963635500     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules21020135     Document Type: Article
Times cited : (71)

References (40)
  • 1
    • 0030176193 scopus 로고    scopus 로고
    • Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potential
    • [CrossRef]
    • Hoult, J.R.; Payá, M. Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potential. Gen. Pharmacol. 1996, 27, 713-722. [CrossRef]
    • (1996) Gen. Pharmacol. , vol.27 , pp. 713-722
    • Hoult, J.R.1    Payá, M.2
  • 2
    • 84940176724 scopus 로고    scopus 로고
    • Hydrogen. Peroxide scavenging activity of novel coumarins synthesized using different approaches
    • [CrossRef]
    • Al-Amiery, A.A.; Al-Majedy, Y.K.; Kadhum, A.A.H.; Mohamad, A.B. Hydrogen. Peroxide Scavenging Activity of Novel Coumarins Synthesized Using Different Approaches. PLoS ONE 2015, 10, e0132175. [CrossRef]
    • (2015) PLoS ONE , vol.10 , pp. e0132175
    • Al-Amiery, A.A.1    Al-Majedy, Y.K.2    Kadhum, A.A.H.3    Mohamad, A.B.4
  • 3
    • 79958856064 scopus 로고    scopus 로고
    • Antioxidantroperties of 5,7-dihydroxy coumarin derivatives in vitro cell free and cell-containing system
    • [CrossRef]
    • Lin, M.H.; Chou, Y.S.; Tsai, Y.J.; Chou, D.S. Antioxidantroperties of 5,7-dihydroxy coumarin derivatives in vitro cell free and cell-containing system. J. Exp. Clin. Med. 2011, 3, 126-131. [CrossRef]
    • (2011) J. Exp. Clin. Med. , vol.3 , pp. 126-131
    • Lin, M.H.1    Chou, Y.S.2    Tsai, Y.J.3    Chou, D.S.4
  • 4
    • 84934762839 scopus 로고    scopus 로고
    • Novel macromolecules derived from coumarin: Synthesis and antioxidant activity
    • [CrossRef] [PubMed]
    • Al-Amiery, A.A.; Al-Majedy, Y.K.; Kadhum, A.A.H.; Mohamad, A.B. Novel macromolecules derived from coumarin: Synthesis and antioxidant activity. Sci. Rep. 2015, 5, 11825. [CrossRef] [PubMed]
    • (2015) Sci. Rep. , vol.5 , pp. 11825
    • Al-Amiery, A.A.1    Al-Majedy, Y.K.2    Kadhum, A.A.H.3    Mohamad, A.B.4
  • 5
    • 0025663358 scopus 로고
    • The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds
    • [CrossRef] [PubMed]
    • Egan, D.; O'Kennedy, R.; Moran, E.; Cox, D.; Prosser, E.; Thornes, R.D. The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds. Drug Metab. Rev. 1990, 22, 503-529. [CrossRef] [PubMed]
    • (1990) Drug Metab. Rev. , vol.22 , pp. 503-529
    • Egan, D.1    O'Kennedy, R.2    Moran, E.3    Cox, D.4    Prosser, E.5    Thornes, R.D.6
  • 7
    • 33646011729 scopus 로고    scopus 로고
    • Long-Chain 3-Acyl-4-hydroxycoumarins: Structure and antibacterial activity
    • [CrossRef] [PubMed]
    • Cravotto, G.; Tagliapietra, S.; Capello, R.; Palmisano, G.; Curini, M.; Boccalini, M. Long-Chain 3-Acyl-4-hydroxycoumarins: Structure and Antibacterial Activity. Arch. Pharm. 2006, 339, 129-132. [CrossRef] [PubMed]
    • (2006) Arch. Pharm. , vol.339 , pp. 129-132
    • Cravotto, G.1    Tagliapietra, S.2    Capello, R.3    Palmisano, G.4    Curini, M.5    Boccalini, M.6
  • 8
    • 84897544142 scopus 로고    scopus 로고
    • Anticancer activity of new coumarin substituted hydrazide-hydrazone derivative
    • [CrossRef] [PubMed]
    • Naser, T.; Bondock, S.; Youns, M. Anticancer activity of new coumarin substituted hydrazide-hydrazone derivative. Eur. J. Med. Chem. 2014, 76, 299-305. [CrossRef] [PubMed]
    • (2014) Eur. J. Med. Chem. , vol.76 , pp. 299-305
    • Naser, T.1    Bondock, S.2    Youns, M.3
  • 9
    • 84949604050 scopus 로고    scopus 로고
    • Implication of coumarins towards central nervous system disorders
    • [CrossRef] [PubMed]
    • Skalicka-Woźniak, K.; Orhan, E.; Cordell, G.; Nabavi, S.; Budzyńska, B. Implication of coumarins towards central nervous system disorders. Pharmacol. Res. 2016, 103, 188-203. [CrossRef] [PubMed]
    • (2016) Pharmacol. Res. , vol.103 , pp. 188-203
    • Skalicka-Woźniak, K.1    Orhan, E.2    Cordell, G.3    Nabavi, S.4    Budzyńska, B.5
  • 10
    • 84879065940 scopus 로고    scopus 로고
    • Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics
    • [CrossRef] [PubMed]
    • Chen, Y.; Chen, Y.; Wang, S.; Xu, X.; Liu, X.; Yu, M.; Zhao, S.; Liu, S.; Qiu, Y.; Zhang, T.; et al. Synthesis and Biological Investigation of Coumarin Piperazine (Piperidine) Derivatives as Potential Multireceptor Atypical Antipsychotics. J. Med. Chem. 2013, 56, 4671-4690. [CrossRef] [PubMed]
    • (2013) J. Med. Chem. , vol.56 , pp. 4671-4690
    • Chen, Y.1    Chen, Y.2    Wang, S.3    Xu, X.4    Liu, X.5    Yu, M.6    Zhao, S.7    Liu, S.8    Qiu, Y.9    Zhang, T.10
  • 11
    • 84871544926 scopus 로고    scopus 로고
    • Ultrasound-promoted greener synthesis of novel trifurcate 3-substituted-chroman-2,4-dione derivatives and their drug-likeness evaluation
    • [CrossRef] [PubMed]
    • Liang, C.; Jiang, H.; Zhou, Z.; Lei, D.; Xue, Y.; Yao, Q. Ultrasound-promoted greener synthesis of novel trifurcate 3-substituted-chroman-2,4-dione derivatives and their drug-likeness evaluation. Molecules 2012, 17, 14146-14158. [CrossRef] [PubMed]
    • (2012) Molecules , vol.17 , pp. 14146-14158
    • Liang, C.1    Jiang, H.2    Zhou, Z.3    Lei, D.4    Xue, Y.5    Yao, Q.6
  • 12
    • 84872103971 scopus 로고    scopus 로고
    • Greener protocol for one pot synthesis of coumarin styryl dyes
    • [CrossRef]
    • Phadtare, B.; Jarag, K.; Shankarling, G. Greener protocol for one pot synthesis of coumarin styryl dyes. Dyes Pigments 2013, 97, 105-112. [CrossRef]
    • (2013) Dyes Pigments , vol.97 , pp. 105-112
    • Phadtare, B.1    Jarag, K.2    Shankarling, G.3
  • 13
    • 2542519416 scopus 로고    scopus 로고
    • Synthesis of some coumarin derivatives as potential laser dyes
    • [CrossRef]
    • Elnagdi, M.; Abdallah, S.; Ghoneim, K.; Ebied, E.; Kassab, K. Synthesis of Some Coumarin Derivatives as Potential Laser Dyes. J. Chem. Res. 1997, 44-45. [CrossRef]
    • (1997) J. Chem. Res. , pp. 44-45
    • Elnagdi, M.1    Abdallah, S.2    Ghoneim, K.3    Ebied, E.4    Kassab, K.5
  • 16
    • 84892575344 scopus 로고    scopus 로고
    • Coumarin-based fluorescent probes for dual recognition of copper(II) and iron(III) ions and their application in bio-imaging
    • [CrossRef] [PubMed]
    • Garcia-Belto, O.; Cassels, B.K.; Pérez, C.; Mena, N.; Nuez, M.T.; Martnez, N.P.; Pavez, P.; Aliaga, M.E. Coumarin-based fluorescent probes for dual recognition of copper(II) and iron(III) ions and their application in bio-imaging. Sensors 2014, 14, 1358-1371. [CrossRef] [PubMed]
    • (2014) Sensors , vol.14 , pp. 1358-1371
    • Garcia-Belto, O.1    Cassels, B.K.2    Pérez, C.3    Mena, N.4    Nuez, M.T.5    Martnez, N.P.6    Pavez, P.7    Aliaga, M.E.8
  • 17
    • 0000147377 scopus 로고
    • Molecular hyperpolarize abilities of coumarin dyes
    • [CrossRef]
    • Moylan, C.R. Molecular hyperpolarize abilities of coumarin dyes. J. Phys. Chem. 1994, 98, 13513-13516. [CrossRef]
    • (1994) J. Phys. Chem. , vol.98 , pp. 13513-13516
    • Moylan, C.R.1
  • 18
    • 77952002333 scopus 로고    scopus 로고
    • 2+-promoted hydrolysis of lactone moiety incoumarin
    • [CrossRef] [PubMed]
    • 2+-promoted hydrolysis of lactone moiety incoumarin. Chem. Commun. 2010, 46, 3363-3365. [CrossRef] [PubMed]
    • (2010) Chem. Commun. , vol.46 , pp. 3363-3365
    • Li, N.1    Xiang, Y.2    Tong, A.3
  • 19
    • 80052230784 scopus 로고    scopus 로고
    • Synthesis, characterization, theoretical crystal structure, and antibacterial activities of some transition metal complexes of the thiosemicarbazone
    • [CrossRef] [PubMed]
    • Al-Amiery, A.A.; Al-Majedy, Y.K.; Abdulreazak, H.; Abood, H. Synthesis, characterization, theoretical crystal structure, and antibacterial activities of some transition metal complexes of the thiosemicarbazone. Bioinorg. Chem. Appl. 2011, 2011, 1-6. [CrossRef] [PubMed]
    • (2011) Bioinorg. Chem. Appl. , vol.2011 , pp. 1-6
    • Al-Amiery, A.A.1    Al-Majedy, Y.K.2    Abdulreazak, H.3    Abood, H.4
  • 20
    • 0033041632 scopus 로고    scopus 로고
    • Effect of plant extracts on the oxidative stability of sunflower oil and emulsion
    • [CrossRef]
    • Abdalla, A.E.; Roozen, J.P. Effect of plant extracts on the oxidative stability of sunflower oil and emulsion. Food Chem. 1999, 64, 323-329. [CrossRef]
    • (1999) Food Chem. , vol.64 , pp. 323-329
    • Abdalla, A.E.1    Roozen, J.P.2
  • 21
    • 79959393093 scopus 로고    scopus 로고
    • Oxidants and antioxidants: State of the art
    • [CrossRef]
    • Bast, A.; Haenen, G.R.; Doelman, C.J. Oxidants and antioxidants: State of the art. Am. J. Med. 1999, 30, 2-13. [CrossRef]
    • (1999) Am. J. Med. , vol.30 , pp. 2-13
    • Bast, A.1    Haenen, G.R.2    Doelman, C.J.3
  • 22
    • 0028060024 scopus 로고
    • Superoxide scavenging activity in leucocytes and absence of cellular toxicity of a series of coumarins
    • [CrossRef]
    • Paya, M.; Goodwin, P.A.; de Las Heras, B.; Hoult, J.R. Superoxide scavenging activity in leucocytes and absence of cellular toxicity of a series of coumarins. Biochem. Pharmacol. 1994, 48, 445-451. [CrossRef]
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 445-451
    • Paya, M.1    Goodwin, P.A.2    De Las-Heras, B.3    Hoult, J.R.4
  • 23
    • 59649098885 scopus 로고    scopus 로고
    • Synthesis of hydroxycoumarins and hydroxybenzo[f ]- or [h]coumarins as lipid peroxidation inhibitors
    • [CrossRef] [PubMed]
    • Symeonidis, T.; Chamilos, M.; Hadjipavlou-Litina, D.J.; Kallitsakis, M.; Litinas, K.E. Synthesis of hydroxycoumarins and hydroxybenzo[f ]- or [h]coumarins as lipid peroxidation inhibitors. Bioorg. Med. Chem. Lett. 2009, 19, 1139-1142. [CrossRef] [PubMed]
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 1139-1142
    • Symeonidis, T.1    Chamilos, M.2    Hadjipavlou-Litina, D.J.3    Kallitsakis, M.4    Litinas, K.E.5
  • 24
    • 6944222563 scopus 로고    scopus 로고
    • Natural and synthetic coumarin derivatives with anti-inflammatory/antioxidant activities
    • [CrossRef] [PubMed]
    • Fylaktakidou, K.C.; Hadjipavlou-Litina, D.J.; Litinas, K.; Nicolaides, D.N. Natural and synthetic coumarin derivatives with anti-inflammatory/antioxidant activities. Curr. Pharm. Des. 2004, 10, 3813-3833. [CrossRef] [PubMed]
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 3813-3833
    • Fylaktakidou, K.C.1    Hadjipavlou-Litina, D.J.2    Litinas, K.3    Nicolaides, D.N.4
  • 25
    • 33646557284 scopus 로고    scopus 로고
    • Synthetic and natural coumarins as antioxidants
    • [CrossRef] [PubMed]
    • Kostova, I. Synthetic and natural coumarins as antioxidants. Mini Rev. Med. Chem. 2006, 6, 365-374. [CrossRef] [PubMed]
    • (2006) Mini Rev. Med. Chem. , vol.6 , pp. 365-374
    • Kostova, I.1
  • 26
    • 56149107352 scopus 로고    scopus 로고
    • Comparative antioxidant capacities of phenolic compounds measured by various tests
    • [CrossRef]
    • Tabart, J.; Kevers, C.; Pincelmail, J.; Defraigne, J.O.; Dommes, J. Comparative antioxidant capacities of phenolic compounds measured by various tests. Food Chem. 2009, 113, 1226-1233. [CrossRef]
    • (2009) Food Chem. , vol.113 , pp. 1226-1233
    • Tabart, J.1    Kevers, C.2    Pincelmail, J.3    Defraigne, J.O.4    Dommes, J.5
  • 27
    • 80052256502 scopus 로고    scopus 로고
    • Antimicrobial and antioxidant activities of new metal complexes derived from 3-aminocoumarin
    • [CrossRef] [PubMed]
    • Kadhum, A.A.H.; Mohamad, A.B.; Al-Amiery, A.A.; Takriff, M.S. Antimicrobial and antioxidant activities of new metal complexes derived from 3-aminocoumarin. Molecules 2011, 16, 6969-6984. [CrossRef] [PubMed]
    • (2011) Molecules , vol.16 , pp. 6969-6984
    • Kadhum, A.A.H.1    Mohamad, A.B.2    Al-Amiery, A.A.3    Takriff, M.S.4
  • 28
    • 84856734956 scopus 로고    scopus 로고
    • Cytotoxicity, antioxidant and antimicrobial activities of novel 2-quinolone derivatives derived from coumarins
    • [CrossRef]
    • Al-Amiery, A.A.; Al-Bayati, R.I.H.; Saour, K.Y.; Radi, M.F. Cytotoxicity, antioxidant and antimicrobial activities of novel 2-quinolone derivatives derived from coumarins. Res. Chem. Intermed. 2011, 38, 559-569. [CrossRef]
    • (2011) Res. Chem. Intermed. , vol.38 , pp. 559-569
    • Al-Amiery, A.A.1    Al-Bayati, R.I.H.2    Saour, K.Y.3    Radi, M.F.4
  • 29
    • 84864383209 scopus 로고    scopus 로고
    • Antioxidant, antimicrobial, and theoretical studies of the thiosemicarbazone derivative Schiff base 2-(2-imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide (IMHC)
    • [CrossRef] [PubMed]
    • Al-Amiery, A.; Al-Majedy, Y.; Ibrahim, H.; Al-Tamimi, A. Antioxidant, antimicrobial, and theoretical studies of the thiosemicarbazone derivative Schiff base 2-(2-imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide (IMHC). Org. Med. Chem. Lett. 2012, 2, 1-7. [CrossRef] [PubMed]
    • (2012) Org. Med. Chem. Lett. , vol.2 , pp. 1-7
    • Al-Amiery, A.1    Al-Majedy, Y.2    Ibrahim, H.3    Al-Tamimi, A.4
  • 30
    • 80053195302 scopus 로고    scopus 로고
    • The antioxidant activity of new coumarin derivatives
    • [CrossRef] [PubMed]
    • Kadhum, A.A.H.; Al-Amiery, A.A.; Musa, A.Y.; Mohamad, A. The antioxidant activity of new coumarin derivatives. Int. J. Mol. Sci. 2012, 12, 5747-5761. [CrossRef] [PubMed]
    • (2012) Int. J. Mol. Sci. , vol.12 , pp. 5747-5761
    • Kadhum, A.A.H.1    Al-Amiery, A.A.2    Musa, A.Y.3    Mohamad, A.4
  • 31
    • 84885634096 scopus 로고    scopus 로고
    • Synthesis and antioxidant activities of novel 5-chlorocurcumin, complemented by semiempirical calculations
    • [CrossRef] [PubMed]
    • Al-Amiery, A.; Kadhum, A.; Obayes, H.; Mohamad, A. Synthesis and Antioxidant Activities of Novel 5-Chlorocurcumin, Complemented by Semiempirical Calculations. Bioinorg. Chem. Appl. 2013, 2013, 1-7. [CrossRef] [PubMed]
    • (2013) Bioinorg. Chem. Appl. , vol.2013 , pp. 1-7
    • Al-Amiery, A.1    Kadhum, A.2    Obayes, H.3    Mohamad, A.4
  • 32
    • 82955168302 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester (CAPE): Correlation of structure and antioxidant properties
    • [CrossRef] [PubMed]
    • Gocer, H.; Gulcin, I. Caffeic acid phenethyl ester (CAPE): Correlation of structure and antioxidant properties. Int. J. Food Sci. Nutr. 2011, 62, 821-825. [CrossRef] [PubMed]
    • (2011) Int. J. Food Sci. Nutr. , vol.62 , pp. 821-825
    • Gocer, H.1    Gulcin, I.2
  • 33
    • 56949085849 scopus 로고    scopus 로고
    • Enzymatic synthesis of caffeic acid phenethyl ester
    • [CrossRef]
    • Widjaja, A.; Yeh, H.; Ju, H. Enzymatic synthesis of caffeic acid phenethyl ester. J. Chin. Inst. Chem. Eng. 2008, 39, 413-418. [CrossRef]
    • (2008) J. Chin. Inst. Chem. Eng. , vol.39 , pp. 413-418
    • Widjaja, A.1    Yeh, H.2    Ju, H.3
  • 34
    • 0032782428 scopus 로고    scopus 로고
    • 2,2-Diphenyl-1-picrylhydrazyl radical-scavenging active components from Polygonum multiflorum Thunb
    • [CrossRef] [PubMed]
    • Chen, Y.; Wang, M.; Rosen, T.; Ho, C. 2,2-Diphenyl-1-picrylhydrazyl radical-scavenging active components from Polygonum multiflorum Thunb. J. Agric. Food Chem. 1999, 47, 2226-2228. [CrossRef] [PubMed]
    • (1999) J. Agric. Food Chem. , vol.47 , pp. 2226-2228
    • Chen, Y.1    Wang, M.2    Rosen, T.3    Ho, C.4
  • 35
    • 0004142037 scopus 로고    scopus 로고
    • 7th ed.; McGraw-Hill: New York, NY, USA
    • Chang, R. Chemistry, 7th ed.; McGraw-Hill: New York, NY, USA, 2001; Volume 253.
    • (2001) Chemistry , vol.253
    • Chang, R.1
  • 36
    • 80052236000 scopus 로고    scopus 로고
    • The use of umbelliferone in the synthesis of new heterocyclic compounds
    • [CrossRef] [PubMed]
    • Al-Amiery, A.; Musa, A.; Kadhum, A.; Mohamad, A. The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds. Molecules 2011, 16, 6833-6843. [CrossRef] [PubMed]
    • (2011) Molecules , vol.16 , pp. 6833-6843
    • Al-Amiery, A.1    Musa, A.2    Kadhum, A.3    Mohamad, A.4
  • 37
    • 0036178812 scopus 로고    scopus 로고
    • Anti-oxidant activity of flavonoids from Licania licaniaeflora
    • [CrossRef]
    • Braca, A.; Sortino, C.; Politi, M.; Morelli, I.; Mendez, J. Anti-oxidant activity of flavonoids from Licania licaniaeflora. J. Ethnopharmacol. 2002, 79, 379-381. [CrossRef]
    • (2002) J. Ethnopharmacol. , vol.79 , pp. 379-381
    • Braca, A.1    Sortino, C.2    Politi, M.3    Morelli, I.4    Mendez, J.5
  • 39
    • 0000492912 scopus 로고    scopus 로고
    • Antioxidant activity of water extract of harng jyur (chrysanthemum morifolium Ramat)
    • [CrossRef]
    • Duh, P.; Tu, Y.; Yen, G. Antioxidant Activity of Water Extract of Harng Jyur (Chrysanthemum morifolium Ramat). LWT Food Sci. Technol. 1999, 32, 269-277. [CrossRef]
    • (1999) LWT Food Sci. Technol. , vol.32 , pp. 269-277
    • Duh, P.1    Tu, Y.2    Yen, G.3
  • 40
    • 21144432550 scopus 로고    scopus 로고
    • Determination of in vitro antioxidant and radical scavenging activities of propofol
    • Ilhami, G.I.; Haci, A.A.; Mehmet, C. Determination of in Vitro Antioxidant and Radical Scavenging Activities of Propofol. Chem. Pharmacol. Bull. 2005, 53, 281-285.
    • (2005) Chem. Pharmacol. Bull. , vol.53 , pp. 281-285
    • Ilhami, G.I.1    Haci, A.A.2    Mehmet, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.