Berberine in combination with yohimbine attenuates sepsis-induced neutrophil tissue infiltration and multiorgan dysfunction partly via IL-10-mediated inhibition of CCR2 expression in neutrophils

International Immunopharmacology

Volumn 35, Issue , 2016, Pages 217-225

  Wang, Yuan ^a   Wang, Faqiang ^a   Yang, Duomeng ^a   Tang, Xiangxu ^a   Li, Hongmei ^a   Lv, Xiuxiu ^a   Lu, Daxiang ^a   Wang, Huadong ^a  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

Berberine; Chemokine receptor CCR2; IL 10; Sepsis; Yohimbine

Indexed keywords

BERBERINE; CHEMOKINE RECEPTOR CCR2; CXCL3 CHEMOKINE; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; YOHIMBINE; BLOCKING ANTIBODY; CCR2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CONTROLLED STUDY; LUNG PARENCHYMA; MALE; MOUSE; MULTIPLE ORGAN FAILURE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CECUM; CELL CULTURE; CELL MOTION; COMBINATION DRUG THERAPY; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGY; INBRED MOUSE STRAIN; METABOLISM; PHYSIOLOGY; SEPSIS; SURGERY;

ANIMALS; ANTIBODIES, BLOCKING; BERBERINE; CECUM; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; HUMANS; INTERLEUKIN-10; MALE; MICE; MICE, INBRED STRAINS; MULTIPLE ORGAN FAILURE; NEUTROPHILS; RECEPTORS, CCR2; SEPSIS; YOHIMBINE;

EID: 84963626022     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2016.03.041     Document Type: Article

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