Endogenous IL-10 leads to impaired bacterial clearance and reduced survival in a murine model of chronic peritonitis

Cytokine

Volumn 40, Issue 3, 2007, Pages 207-215

  Lenz, Andreas M ^a   Franklin, Glen A ^a   Fairweather, Mark ^a   McClintock, Michael L ^a   Jala, Venkatakrishna R ^b   Peyton, James C ^a   Gardner, Sarah A ^a   Cheadle, William G ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Anti IL 10 antibody; Chronic peritonitis; IL 10; Klebsiella; Murine

Indexed keywords

GENTAMICIN; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BACTERIAL SURVIVAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNE RESPONSE; KLEBSIELLA PNEUMONIAE; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PERITONEAL FLUID; PERITONITIS; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; GENTAMICINS; INTERLEUKIN-10; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MICE; MICE, INBRED BALB C; PERITONITIS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS); KLEBSIELLA; KLEBSIELLA PNEUMONIAE; MURINAE;

EID: 36749067341     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2007.09.012     Document Type: Article

References (49)

1. Barie P.S., Hydo L.J., and Eachempati S.R. Longitudinal outcomes of intra-abdominal infection complicated by critical illness. Surg Infect 5 (2004) 365-373
2. Fry D.E., Pearlstein L., Fulton R.L., and Polk Jr. H.C. Multiple system organ failure. The role of uncontrolled infection. Arch Surg 115 (1980) 136-140
3. Nathens A.B., Rotstein O.D., and Marshall J.C. Tertiary peritonitis: clinical features of a complex nosocomial infection. World J Surg 22 (1998) 158-163
4. Deitch E.A. Rodent models of intra-abdominal infection. Shock 24 Suppl 1 (2005) 19-23
5. Hau T., Ahrenholz D.H., and Simmons R.L. Secondary bacterial peritonitis: the biologic basis of treatment. Curr Probl Surg 16 (1979) 1-65
6. Saini S., Gupta N., Lokveer A., and Griwan M.S. Surgical infections: a microbiological study. Braz J Infect Dis 8 (2004) 118-125
7. Brook I., and Frazier E.H. Aerobic and anaerobic microbiology in intra-abdominal infections associated with diverticulitis. J Med Microbiol 49 (2000) 827-830
8. Podschun R., and Ullmann U. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 11 (1998) 589-603
9. Bouza E., and Cercenado E. Klebsiella and enterobacter: antibiotic resistance and treatment implications. Semin Respir Infect 17 (2002) 215-230
10. Schurr J.R., Young E., Byrne P., Steele C., Shellito J.E., and Kolls J.K. Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria. Infect Immun 73 (2005) 532-545
11. Van Amersfoort E.S., Van Berkel T.J., and Kuiper J. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin Microbiol Rev 16 (2003) 379-414
12. Wu J.H., Hong L.C., Tsai Y.Y., Chen H.W., Chen W.X., and Wu T.S. Mitogen-activated protein kinase (MAPK) signalling pathways in HepG2 cells infected with a virulent strain of Klebsiella pneumoniae. Cell Microbiol 8 (2006) 1467-1474
13. Yoshida K., Matsumoto T., Tateda K., Uchida K., Tsujimoto S., and Yamaguchi K. Induction of interleukin-10 and down regulation of cytokine production by Klebsiella pneumoniae capsule in mice with pulmonary infection. J Med Microbiol 50 (2001) 456-461
14. Kabha K., Nissimov L., Athamna A., Keisari Y., Parolis H., Parolis L.A., et al. Relationships among capsular structure, phagocytosis, and mouse virulence in Klebsiella pneumoniae. Infect Immun 63 (1995) 847-852
15. Woods D.R., Peyton J.C., Franklin G.A., Turina M., and Cheadle W.G. Decreased neutrophil response in a chronic intraperitoneal klebsiella infection model. Surg Infect 8 (2007) 367-376
16. Ferrer T.J., Webb J.W., Wallace B.H., Bridges C.D., Palmer H.E., Robertson R.D., et al. Interleukin-10 reduces morbidity and mortality in murine multiple organ dysfunction syndrome (MODS). J Surg Res 77 (1998) 157-164
17. Sewnath M.E., Olszyna D.P., Birjmohun R., ten Kate F.J., Gouma D.J., and van Der Poll T. IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance. J Immunol 166 (2001) 6323-6331
18. Scott M.J., Hoth J.J., Turina M., Woods D.R., and Cheadle W.G. Interleukin-10 suppresses natural killer cell but not natural killer T cell activation during bacterial infection. Cytokine 33 (2006) 79-86
19. Kato T., Murata A., Ishida H., Toda H., Tanaka N., Hayashida H., et al. Interleukin 10 reduces mortality from severe peritonitis in mice. Antimicrob Agents Chemother 39 (1995) 1336-1340
20. Gomes R.N., Figueiredo R.T., Bozza F.A., Pacheco P., Amancio R.T., Laranjeira A.P., et al. Increased susceptibility to septic and endotoxic shock in monocyte chemoattractant protein 1/cc chemokine ligand 2-deficient mice correlates with reduced interleukin 10 and enhanced macrophage migration inhibitory factor production. Shock 26 (2006) 457-463
21. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods 25 (2001) 402-408
22. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19 (2001) 683-765
23. Staples K.J., Smallie T., Williams L.M., Foey A., Burke B., Foxwell B.M., et al. IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3. J Immunol 178 (2007) 4779-4785
24. Pestka S., Krause C.D., Sarkar D., Walter M.R., Shi Y., and Fisher P.B. Interleukin-10 and related cytokines and receptors. Annu Rev Immunol 22 (2004) 929-979
25. van Der Poll T., Marchant A., Buurman W.A., Berman L., Keogh C.V., Lazarus D.D., et al. Endogenous IL-10 protects mice from death during septic peritonitis. J Immunol 155 (1995) 5397-5401
26. Berg D.J., Kuhn R., Rajewsky K., Muller W., Menon S., Davidson N., et al. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J Clin Invest 96 (1995) 2339-2347
27. Marchant A., Bruyns C., Vandenabeele P., Ducarme M., Gerard C., Delvaux A., et al. Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia. Eur J Immunol 24 (1994) 1167-1171
28. Gerard C., Bruyns C., Marchant A., Abramowicz D., Vandenabeele P., Delvaux A., et al. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med 177 (1993) 547-550
29. Florquin S., Amraoui Z., Abramowicz D., and Goldman M. Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice. J Immunol 153 (1994) 2618-2623
30. Remick D.G., Garg S.J., Newcomb D.E., Wollenberg G., Huie T.K., and Bolgos G.L. Exogenous interleukin-10 fails to decrease the mortality or morbidity of sepsis. Crit Care Med 26 (1998) 895-904
31. Tonnetti L., Spaccapelo R., Cenci E., Mencacci A., Puccetti P., Coffman R.L., et al. Interleukin-4 and -10 exacerbate candidiasis in mice. Eur J Immunol 25 (1995) 1559-1565
32. Song G.Y., Chung C.S., Chaudry I.H., and Ayala A. What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant?. Surgery 126 (1999) 378-383
33. Silva R.A., Pais T.F., and Appelberg R. Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccination. J Immunol 167 (2001) 1535-1541
34. Murray H.W. Interleukin 10 receptor blockade-pentavalent antimony treatment in experimental visceral leishmaniasis. Acta Trop 93 (2005) 295-301
35. Murray H.W., Lu C.M., Mauze S., Freeman S., Moreira A.L., Kaplan G., et al. Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infect Immun 70 (2002) 6284-6293
36. Silva R.A., and Appelberg R. Blocking the receptor for interleukin 10 protects mice from lethal listeriosis. Antimicrob Agents Chemother 45 (2001) 1312-1314
37. Greenberger M.J., Strieter R.M., Kunkel S.L., Danforth J.M., Goodman R.E., and Standiford T.J. Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia. J Immunol 155 (1995) 722-729
38. Wang M., Jeng K.C., and Ping L.I. Exogenous cytokine modulation or neutralization of interleukin-10 enhance survival in lipopolysaccharide-hyporesponsive C3H/HeJ mice with Klebsiella infection. Immunology 98 (1999) 90-97
39. Abe T., Arai T., Ogawa A., Hiromatsu T., Masuda A., Matsuguchi T., et al. Kupffer cell-derived interleukin 10 is responsible for impaired bacterial clearance in bile duct-ligated mice. Hepatology 40 (2004) 414-423
40. Powell M.J., Thompson S.A., Tone Y., Waldmann H., and Tone M. Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region. J Immunol 165 (2000) 292-296
41. Tone M., Powell M.J., Tone Y., Thompson S.A., and Waldmann H. IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3. J Immunol 165 (2000) 286-291
42. Kalechman Y., Gafter U., Gal R., Rushkin G., Yan D., Albeck M., et al. Anti-IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: dependence on timing of immunomodulating intervention. J Immunol 169 (2002) 384-392
43. Greenberger M.J., Strieter R.M., Kunkel S.L., Danforth J.M., Goodman R.E., and Standiford T.J. Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia. J Immunol 155 (1995) 722-729
44. van Der Poll T., Marchant A., Keogh C.V., Goldman M., and Lowry S.F. Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis 174 (1996) 994-1000
45. Yoshida K., Matsumoto T., Tateda K., Uchida K., Tsujimoto S., and Yamaguchi K. Role of bacterial capsule in local and systemic inflammatory responses of mice during pulmonary infection with Klebsiella pneumoniae. J Med Microbiol 49 (2000) 1003-1010
46. Lawlor M.S., Handley S.A., and Miller V.L. Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections. Infect Immun 74 (2006) 5402-5407
47. Yoshida K., Matsumoto T., Tateda K., Uchida K., Tsujimoto S., and Yamaguchi K. Induction of interleukin-10 and down-regulation of cytokine production by Klebsiella pneumoniae capsule in mice with pulmonary infection. J Med Microbiol 50 (2001) 456-461
48. Mathiak G., Kabir K., Grass G., Keller H., Steinringer E., Minor T., et al. Lipopolysaccharides from different bacterial sources elicit disparate cytokine responses in whole blood assays. Int J Mol Med 11 (2003) 41-44
49. Ziegeler S., Raddatz A., Hoff G., Buchinger H., Bauer I., Stockhausen A., et al. Antibiotics modulate the stimulated cytokine response to endotoxin in a human ex vivo, in vitro model. Acta Anaesthesiol Scand 50 (2006) 1103-1110