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Volumn 779, Issue , 2016, Pages 8-21

Treatments for post-menopausal osteoporotic women, what's new? How can we manage long-term treatment?

Author keywords

Bisphosphonate; Cathepsin K; Denosumab; Long term Treatment; Postmenopausal Osteoporosis; Romosozumab

Indexed keywords

ALENDRONIC ACID; BALICATIB; BAZEDOXIFENE; BLOSOZUMAB; CALCITONIN; CATHEPSIN K INHIBITOR; DENOSUMAB; ESTROGEN DERIVATIVE; IBANDRONIC ACID; ODANACATIB; ONO 5334; PARATHYROID HORMONE[1-34]; RALOXIFENE; RELACATIB; RISEDRONIC ACID; ROMOSOZUMAB; STRONTIUM RANELATE; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

EID: 84963623282     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.02.053     Document Type: Review
Times cited : (15)

References (51)
  • 1
    • 84963498290 scopus 로고    scopus 로고
    • risk communications Ref 2009/10, last accesed on 13.10.14
    • AEMPS, 2014. Drug Description, (drug safety). (risk communications Ref 2009/10, last accesed on 13.10.14).
    • (2014) Drug Description, (Drug Safety)
    • AEMPS1
  • 4
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group
    • D.M. Black, S.R. Cummings, D.B. Karpf, and et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group Lancet 348 9041 1996 1535 1541
    • (1996) Lancet , vol.348 , Issue.9041 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3
  • 5
    • 33845890326 scopus 로고    scopus 로고
    • Effects of continuing or stopping alendronate after 5 years of treatment: The fracture intervention trial long-term extension (FLEX): A randomized trial
    • D.M. Black, A.V. Schwartz, K.E. Ensrud, J.A. Cauley, S. Levis, S.A. Quandt, and et al. Effects of continuing or stopping alendronate after 5 years of treatment: the fracture intervention trial long-term extension (FLEX): a randomized trial JAMA 296 2006 2927 2938
    • (2006) JAMA , vol.296 , pp. 2927-2938
    • Black, D.M.1    Schwartz, A.V.2    Ensrud, K.E.3    Cauley, J.A.4    Levis, S.5    Quandt, S.A.6
  • 7
    • 0033829969 scopus 로고    scopus 로고
    • A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: The prevent recurrence of osteoporotic fractures study. PROOF study group
    • C.H. Chesnut, S. Silverman, K. Andriano, and et al. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF study group Am J. Med. 109 4 2000 267 276
    • (2000) Am J. Med. , vol.109 , Issue.4 , pp. 267-276
    • Chesnut, C.H.1    Silverman, S.2    Andriano, K.3
  • 8
    • 4544262219 scopus 로고    scopus 로고
    • Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis
    • C.H. Chesnut, A. Skag, C. Christiansen, and et al. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis J. Bone Miner. Res. 19 18 2004 1241 1249
    • (2004) J. Bone Miner. Res. , vol.19 , Issue.18 , pp. 1241-1249
    • Chesnut, C.H.1    Skag, A.2    Christiansen, C.3
  • 9
    • 75849124774 scopus 로고    scopus 로고
    • accessed October 30.10.14
    • Clinical Trials, 2014. (accessed October 30.10.14).
    • (2014) Clinical Trials
  • 10
    • 84856147111 scopus 로고    scopus 로고
    • Bisphosphonate therapy for osteoporosis: The long and short of it
    • February
    • J.E. Compston, and J.P. Bilezikian Bisphosphonate therapy for osteoporosis: the long and short of it J. Bone Miner. Res. 27 2 2012 240 242 February
    • (2012) J. Bone Miner. Res. , vol.27 , Issue.2 , pp. 240-242
    • Compston, J.E.1    Bilezikian, J.P.2
  • 11
    • 84887487997 scopus 로고    scopus 로고
    • Odanacatib in postmenopausal women with low bone mineral density: A review of current clinical evidence
    • A. Cristiano, F. Zerbini, R. Michael, and McClung Odanacatib in postmenopausal women with low bone mineral density: a review of current clinical evidence Ther. Adv. Musculoskelet. Dis. 5 4 2013 199 209
    • (2013) Ther. Adv. Musculoskelet. Dis. , vol.5 , Issue.4 , pp. 199-209
    • Cristiano, A.1    Zerbini, F.2    Michael, R.3    McClung4
  • 12
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • 765 (Erratum in: N Engl J Med. 2009;361[19]:1914)
    • S.R. Cummings, J. San Martin, M.R. McClung, Denosumab for prevention of fractures in postmenopausal women with osteoporosis N. Engl. J. Med. 361 8 2009 756 765 (Erratum in: N Engl J Med. 2009;361[19]:1914).
    • (2009) N. Engl. J. Med. , vol.361 , Issue.8 , pp. 756
    • Cummings, S.R.1    San Martin, J.2    McClung, M.R.3
  • 14
    • 84887432859 scopus 로고    scopus 로고
    • Bisphosphonate drug holiday: Who, when and how long
    • Jun
    • Dima L. Diab, B. Nelson, and Watts Bisphosphonate drug holiday: who, when and how long Ther. Adv. Musculoskelet. Dis. 5 2013 107 111 Jun
    • (2013) Ther. Adv. Musculoskelet. Dis. , vol.5 , pp. 107-111
    • Diab, D.L.1    Nelson, B.2    Watts3
  • 15
    • 84887011575 scopus 로고    scopus 로고
    • Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: A systematic review
    • E.F. Eriksen, A. Díez-Pérez, and S. Boonen Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: a systematic review Bone 58 2014 126 135
    • (2014) Bone , vol.58 , pp. 126-135
    • Eriksen, E.F.1    Díez-Pérez, A.2    Boonen, S.3
  • 16
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial. Multiple outcomes of raloxifene evaluation (MORE) investigators
    • Erratum in: JAMA.1999;282[22]:2124
    • B. Ettinger, D.M. Black, B.H. Mitlak, and et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple outcomes of raloxifene evaluation (MORE) investigators JAMA 18 7 1999 637 645 (Erratum in: JAMA.1999;282[22]:2124)
    • (1999) JAMA , vol.18 , Issue.7 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3
  • 19
    • 84963623209 scopus 로고    scopus 로고
    • accessed 09.07.14
    • FDA webpage, 2014. (Available at): (accessed 09.07.14).
    • (2014)
  • 20
    • 77951644239 scopus 로고    scopus 로고
    • Effects of teriparatide, alendronate, or both in women with postmenopausal osteoporosis
    • Epub 2010 Feb 17
    • J.S. Finkelstein, J.J. Wyland, H. Lee, and R.M. Neer Effects of teriparatide, alendronate, or both in women with postmenopausal osteoporosis J. Clin. Endocrinol. Metab. 95 4 2010 1838 1845 10.1210/jc.2009-1703 Epub 2010 Feb 17
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.4 , pp. 1838-1845
    • Finkelstein, J.S.1    Wyland, J.J.2    Lee, H.3    Neer, R.M.4
  • 21
    • 78649326406 scopus 로고    scopus 로고
    • Impact of treatments for postmenopausal osteoporosis (bisphosphonates, parathyroid hormone, strontium ranelate and denosumab) on bone quality: A systematic review
    • S.J. Gallacher, and T. Dixon Impact of treatments for postmenopausal osteoporosis (bisphosphonates, parathyroid hormone, strontium ranelate and denosumab) on bone quality: a systematic review Calcif. Tissue Int. 87 2010 469 484
    • (2010) Calcif. Tissue Int. , vol.87 , pp. 469-484
    • Gallacher, S.J.1    Dixon, T.2
  • 22
    • 81355148868 scopus 로고    scopus 로고
    • Effects of one year daily teriparatide treatment on trabecular bone material properties in postmenopausal osteoporotic women previously treated with alendronate or risedronate
    • Epub 2011 Aug 27
    • S. Gamsjaeger, B. Buchinger, R. Zoehrer, R. Phipps, K. Klaushofer, and E.P. Paschalis Effects of one year daily teriparatide treatment on trabecular bone material properties in postmenopausal osteoporotic women previously treated with alendronate or risedronate Bone 49 6 2011 1160 1165 10.1016/j.bone.2011.08.015 Epub 2011 Aug 27
    • (2011) Bone , vol.49 , Issue.6 , pp. 1160-1165
    • Gamsjaeger, S.1    Buchinger, B.2    Zoehrer, R.3    Phipps, R.4    Klaushofer, K.5    Paschalis, E.P.6
  • 26
  • 30
    • 2942715412 scopus 로고    scopus 로고
    • Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: A pragmatic population-based 3-year intervention study
    • E.R. Larsen, L. Mosekilde, and A. Foldspang Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: a pragmatic population-based 3-year intervention study J. Bone Miner. Res. 19 3 2004 370 378
    • (2004) J. Bone Miner. Res. , vol.19 , Issue.3 , pp. 370-378
    • Larsen, E.R.1    Mosekilde, L.2    Foldspang, A.3
  • 31
    • 35748967004 scopus 로고    scopus 로고
    • Zoledronic acid and clinical fractures and mortality after HIP fracture
    • K.W. Lyles, C.S. Colón-Emeric, J.S. Magaziner, and et al. Zoledronic acid and clinical fractures and mortality after HIP fracture N. Eng. J. Med. 357 18 2007 1799 1809
    • (2007) N. Eng. J. Med. , vol.357 , Issue.18 , pp. 1799-1809
    • Lyles, K.W.1    Colón-Emeric, C.S.2    Magaziner, J.S.3
  • 35
  • 38
    • 0035837553 scopus 로고    scopus 로고
    • Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
    • R.M. Neer, C.D. Arnaud, J.R. Zanchetta, and et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis N. Engl. J. Med. 344 19 2001 1434 1441
    • (2001) N. Engl. J. Med. , vol.344 , Issue.19 , pp. 1434-1441
    • Neer, R.M.1    Arnaud, C.D.2    Zanchetta, J.R.3
  • 39
    • 67649382241 scopus 로고    scopus 로고
    • Teripatide vertebral fracture risk reduction determined by quantitative and qualitative radiographic assessment
    • PubMed.gov
    • S. Pervhal, J.H. Krege, P. Chen, H. Genant, and D.M. Black Teripatide vertebral fracture risk reduction determined by quantitative and qualitative radiographic assessment Curr. Med. Res. Opin. 25 4 2009 921 928 PubMed.gov
    • (2009) Curr. Med. Res. Opin. , vol.25 , Issue.4 , pp. 921-928
    • Pervhal, S.1    Krege, J.H.2    Chen, P.3    Genant, H.4    Black, D.M.5
  • 41
    • 12944291524 scopus 로고    scopus 로고
    • Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral efficacy with risedronate therapy (VERT) study group
    • J. Reginster, H.W. Minne, O.H. Sorensen, and et al. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral efficacy with risedronate therapy (VERT) study group Osteoporos. Int. 11 1 2000 83 91
    • (2000) Osteoporos. Int. , vol.11 , Issue.1 , pp. 83-91
    • Reginster, J.1    Minne, H.W.2    Sorensen, O.H.3
  • 43
    • 77952331323 scopus 로고    scopus 로고
    • Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: The FLEX trial
    • A.V. Schwartz, D.C. Bauer, S.R. Cummings, J.A. Cauley, K.E. Ensrud, L. Palermo, and et al. Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial J. Bone Miner. Res. 25 2010 976 982
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 976-982
    • Schwartz, A.V.1    Bauer, D.C.2    Cummings, S.R.3    Cauley, J.A.4    Ensrud, K.E.5    Palermo, L.6
  • 46
    • 84856089598 scopus 로고    scopus 로고
    • Osteoporosis: Burden, health care provision and opportunities in the EU: A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA)
    • O. Ström, F. Borgström, J.A. Kanis, J. Compston, C. Cooper, E. McCloskey, and B. Jönsson Osteoporosis: burden, health care provision and opportunities in the EU: a report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA) Arch Osteoporos 2011 10.1007/s11657-011-0060-1
    • (2011) Arch Osteoporos
    • Ström, O.1    Borgström, F.2    Kanis, J.A.3    Compston, J.4    Cooper, C.5    McCloskey, E.6    Jönsson, B.7
  • 47
    • 84930657142 scopus 로고    scopus 로고
    • Romosozumab and blosozumab: Alternative drugs of mechanical strain-related stimulus toward a cure for osteoporosis
    • Apr
    • T. Sugiyama, T. Torio, T. Miyajima, Y. Kim Taek, and H. Oda Romosozumab and blosozumab: alternative drugs of mechanical strain-related stimulus toward a cure for osteoporosis Front. Endocrinol. 21 2015 10.3389/fendo.2015.00054 Apr
    • (2015) Front. Endocrinol. , vol.21
    • Sugiyama, T.1    Torio, T.2    Miyajima, T.3    Taek, Y.K.4    Oda, H.5
  • 48
    • 0033678399 scopus 로고    scopus 로고
    • Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III osteoporosis treatment study group
    • R.P. Tonino, P.J. Meunier, R. Emkey, J.A. Rodriguez-Portales, C.J. Menkes, R.D. Wasnich, and et al. Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III osteoporosis treatment study group J. Clin. Endocrinol. Metab. 85 2000 3109 3115
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 3109-3115
    • Tonino, R.P.1    Meunier, P.J.2    Emkey, R.3    Rodriguez-Portales, J.A.4    Menkes, C.J.5    Wasnich, R.D.6
  • 51
    • 84900408245 scopus 로고    scopus 로고
    • Effects of eight-month treatment with ONO-5334, a cathepsin K inhibitor, on bone metabolism, strength and microstructure in ovariectomized cynomolgus monkeys
    • Minase Research Institute, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai Shimamoto-cho Mishima-gun, Osaka 618-8585, Japan. Received: August 7, 2013; Received in revised form: April 21, 2014; Accepted: April 21, 2014; Published Online: April 27, 2014
    • Yasuo Ochi, Hiroyuki Yamada, Hiroshi Mori, Yasutomo Nakanishi, Satoshi Nishikawa, Ryoji Kayasuga, Naoki Kawada, Akiko Kunishige, Yasuaki Hashimoto, Makoto Tanaka, Masfumi Sugitani, and Kazuhito Kawabata Effects of eight-month treatment with ONO-5334, a cathepsin K inhibitor, on bone metabolism, strength and microstructure in ovariectomized cynomolgus monkeys Bone 65 2014 1 8 Minase Research Institute, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai Shimamoto-cho Mishima-gun, Osaka 618-8585, Japan. Received: August 7, 2013; Received in revised form: April 21, 2014; Accepted: April 21, 2014; Published Online: April 27, 2014
    • (2014) Bone , vol.65 , pp. 1-8
    • Ochi, Y.1    Yamada, H.2    Mori, H.3    Nakanishi, Y.4    Nishikawa, S.5    Kayasuga, R.6    Kawada, N.7    Kunishige, A.8    Hashimoto, Y.9    Tanaka, M.10    Sugitani, M.11    Kawabata, K.12


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