School and Community Screening Shows Malawi, Africa, to Have a High Prevalence of Latent Rheumatic Heart Disease

Congenital Heart Disease

Volumn 11, Issue 6, 2016, Pages 615-621

  Sims Sanyahumbi, Amy ^a   Sable, Craig A ^b   Beaton, Andrea ^b   Chimalizeni, Yamikani ^c   Guffey, Danielle ^d   Hosseinipour, Mina ^e   Karlsten, Melissa ^a   Kazembe, Peter N ^f   Kennedy, Neil ^c   Minard, Charles G ^d   Penny, Daniel J ^a  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF MALAWI   (Malawi)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF NORTH CAROLINA PROJECT   (Malawi)

^f Baylor College of Medicine Children's Clinical Center of Excellence   (Malawi)

Author keywords

Echocardiography; Pediatrics; Rheumatic Heart Disease; Screening

Indexed keywords

ADOLESCENT; AGE; AORTA VALVE REGURGITATION; ARTICLE; BORDERLINE RHEUMATIC HEART DISEASE; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEFINITE RHEUMATIC HEART DISEASE; ECHOCARDIOGRAPH; ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART VENTRICLE SEPTUM DEFECT; HUMAN; LATENT RHEUMATIC HEART DISEASE; MAJOR CLINICAL STUDY; MALAWI; MALE; MASS SCREENING; MITRAL VALVE PROLAPSE; MITRAL VALVE REGURGITATION; PREVALENCE; PRIORITY JOURNAL; RHEUMATIC HEART DISEASE; SCHOOL CHILD; SEX DIFFERENCE; URBAN RURAL DIFFERENCE; AGE DISTRIBUTION; ASYMPTOMATIC DISEASE; COLOR DOPPLER ECHOCARDIOGRAPHY; COMMUNITY CARE; DIAGNOSTIC IMAGING; HEALTH SURVEY; OBSERVER VARIATION; PREDICTIVE VALUE; PRESCHOOL CHILD; PROCEDURES; REPRODUCIBILITY; SCHOOL HEALTH SERVICE; SEX RATIO;

ADOLESCENT; AGE DISTRIBUTION; ASYMPTOMATIC DISEASES; CHILD; CHILD, PRESCHOOL; COMMUNITY HEALTH SERVICES; CROSS-SECTIONAL STUDIES; ECHOCARDIOGRAPHY, DOPPLER, COLOR; FEMALE; HEALTH SURVEYS; HUMANS; MALAWI; MALE; MASS SCREENING; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; PREVALENCE; REPRODUCIBILITY OF RESULTS; RHEUMATIC HEART DISEASE; SCHOOL HEALTH SERVICES; SEX DISTRIBUTION;

EID: 84963599577     PISSN: 1747079X     EISSN: 17470803     Source Type: Journal    
DOI: 10.1111/chd.12353     Document Type: Article

References (27)

1. Mortality GBD, Causes of Death C. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015;385:117–171.
2. Marijon E, Mirabel M, Celermajer DS, Jouven X. Rheumatic heart disease. Lancet 2012;379:953–964.
3. Seckeler MD, Hoke TR. The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease. Clin Epidemiol. 2011;3:67–84.
4. Sims Sanyahumbi ACS, Wyber R, Carapetis J. Global Disease Burden of Group A Streptococcus. In: Ferretti JJSD, Fischetti VA, eds. Streptococcus Pyogenes: Basic Biology to Clinical Manifestations. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016.
5. Marijon E, Ou P, Celermajer DS, et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007;357:470–476.
6. Saxena A, Ramakrishnan S, Roy A, et al. Prevalence and outcome of subclinical rheumatic heart disease in India: the RHEUMATIC (Rheumatic Heart Echo Utilisation and Monitoring Actuarial Trends in Indian Children) study. Heart 2011;97:2018–2022.
7. Reeves BM, Kado J, Brook M. High prevalence of rheumatic heart disease in Fiji detected by echocardiography screening. J Paediatr Child Health 2011;47:473–478.
8. Remenyi B, Wilson N, Steer A, et al. World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease-an evidence-based guideline. Nat Rev Cardiol. 2012;9:297–309.
9. Remenyi B, Carapetis J, Wyber R, Taubert K, Mayosi BM. Position statement of the World Heart Federation on the prevention and control of rheumatic heart disease. Nat Rev Cardiol. 2013;10:284–292.
10. Rheumatic fever and rheumatic heart disease. World Health Organization technical report series. 2004;923:1–122, back cover.
11. World B. Data Indicators, 2013 GNI per capita. Available at: http://dataworldbankorg/indicator/NYGNPPCAPCD. Accessed on February 2, 2013.
12. Beaton A, Okello E, Lwabi P, Mondo C, McCarter R, Sable C. Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren. Circulation 2012;125:3127–3132.
13. Soliman EZ, Juma H. Cardiac disease patterns in northern Malawi: epidemiologic transition perspective. J Epidemiol. 2008;18:204–208.
14. Kennedy N, Miller P. The spectrum of paediatric cardiac disease presenting to an outpatient clinic in Malawi. BMC Res Notes. 2013;6:53.
15. Beaton A, Lu JC, Aliku T, et al. The utility of handheld echocardiography for early rheumatic heart disease diagnosis: a field study. Eur Heart J Cardiovasc Imaging 2015;16:475–482.
16. Engel ME, Haileamlak A, Zuhlke L, et al. Prevalence of rheumatic heart disease in 4720 asymptomatic scholars from South Africa and Ethiopia. Heart 2015;101:1389–1394.
17. Global Burden of Disease Study C. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015;386:743–800.
18. Manyemba J, Mayosi BM. Penicillin for secondary prevention of rheumatic fever. Cochrane Database Syst Rev. 2002:CD002227.
19. McDonald M, Brown A, Noonan S, Carapetis JR. Preventing recurrent rheumatic fever: the role of register based programmes. Heart 2005;91:1131–1133.
20. Feinstein AR, Wood HF, Spagnuolo M, et al. Rheumatic Fever in Children and Adolescents. A Long-Term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae. Vii. Cardiac Changes and Sequelae. Ann Intern Med. 1964;60:(Suppl. 5):87–123.
21. Zachariah JP, Samnaliev M. Echo-based screening of rheumatic heart disease in children: a cost-effectiveness Markov model. J Med Econ. 2015;18:410–419.
22. Tompkins DG, Boxerbaum B, Liebman J. Long-term prognosis of rheumatic fever patients receiving regular intramuscular benzathine penicillin. Circulation 1972;45:543–551.
23. Kassem AS, el-Walili TM, Zaher SR, Ayman M. Reversibility of mitral regurgitation following rheumatic fever: clinical profile and echocardiographic evaluation. Indian J Pediatr. 1995;62:717–723.
24. Pelajo CF, Lopez-Benitez JM, Torres JM, de Oliveira SK. Adherence to secondary prophylaxis and disease recurrence in 536 Brazilian children with rheumatic fever. Pediatr Rheumatol Online J. 2010;8:22.
25. Karthikeyan G, Zuhlke L, Engel M, et al. Rationale and design of a Global Rheumatic Heart Disease Registry: the REMEDY study. Am Heart J. 2012;163:535–40 e1.
26. UNICEF. Malawi Statistics 2013. Available at: http://www.unicef.org/infobycountry/malawi_statistics.html. Accessed: November 27, 2015.
27. Beaton A, Okello E, Aliku T, et al. Latent rheumatic heart disease: outcomes 2 years after echocardiographic detection. Pediatric Cardiol. 2014;35:1259–1267.