Comparative Risk Predictions of Second Cancers after Carbon-Ion Therapy Versus Proton Therapy

International Journal of Radiation Oncology Biology Physics

Volumn 95, Issue 1, 2016, Pages 279-286

  Eley, John G ^a,b,c   Friedrich, Thomas ^d   Homann, Kenneth L ^a,b   Howell, Rebecca M ^a,b   Scholz, Michael ^d   Durante, Marco ^d   Newhauser, Wayne D ^e,f  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

^e LOUISIANA STATE UNIVERSITY   (United States)

^f MARY BIRD PERKINS CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; FORECASTING; IONS; PROTON BEAMS;

BIOLOGIC TREATMENT; CARBON ION THERAPY; CELL INACTIVATION; COMPETING PROCESS; LINEAR-QUADRATIC MODELS; METHODS AND MATERIALS; RELATIVE BIOLOGICAL EFFECTIVENESS; THEORETICAL FRAMEWORK;

PATIENT TREATMENT;

ADULT; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER PATIENT; CANCER RISK; CELL SURVIVAL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONCEPTUAL FRAMEWORK; FEMALE; FRACTION ABSORBED; HODGKIN DISEASE; HUMAN; ION THERAPY; ORGANS AT RISK; PATIENT RISK; PRIORITY JOURNAL; PROTON THERAPY; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RELATIVE BIOLOGIC EFFECTIVENESS; RISK ASSESSMENT; SECOND CANCER; TREATMENT PLANNING; YOUNG ADULT; ADVERSE EFFECTS; BREAST; BREAST NEOPLASMS; DIAGNOSTIC IMAGING; ESOPHAGUS; HEART; INCIDENCE; LUNG; NEOPLASMS, SECOND PRIMARY; PATHOLOGY; RADIATION RESPONSE; RADIOGRAPHY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING SYSTEM; SENSITIVITY AND SPECIFICITY; SPINAL CORD; STATISTICAL MODEL; UNCERTAINTY;

CARBON;

BREAST; BREAST NEOPLASMS; CARBON; ESOPHAGUS; FEMALE; HEART; HEAVY ION RADIOTHERAPY; HODGKIN DISEASE; HUMANS; INCIDENCE; LINEAR MODELS; LUNG; NEOPLASMS, SECOND PRIMARY; ORGANS AT RISK; PROTON THERAPY; RADIOGRAPHY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RELATIVE BIOLOGICAL EFFECTIVENESS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SPINAL CORD; UNCERTAINTY;

EID: 84963556393     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2016.02.032     Document Type: Article

References (50)

1. M. Jermann Particle Therapy Statistics in 2014 Int J Particle Ther 2 2015 50 54
2. H. Tsujii, and T. Kamada A review of update clinical results of carbon ion radiotherapy Jpn J Clin Oncol 42 2012 670 685
3. L.L. Robison, A.C. Mertens, J.D. Boice, and et al. Study design and cohort characteristics of the childhood cancer survivor study: A multi-institutional collaborative project Med Pediatr Oncol 38 2002 229 239
4. C.S. Chung, T.I. Yock, K. Nelson, and et al. Incidence of second malignancies among patients treated with proton versus photon radiation Int J Radiat Oncol Biol Phys 87 2013 46 52
5. U. Weber, and G. Kraft Comparison of carbon ions versus protons Cancer J 15 2009 325 332
6. T. Elsässer, W.K. Weyrather, T. Friedrich, and et al. Quantification of the relative biological effectiveness for ion beam radiotherapy: Direct experimental comparison of proton and carbon ion beams and a novel approach for treatment planning Int J Radiat Oncol Biol Phys 78 2010 1177 1183
7. D. Schardt, T. Elsässer, and D. Schulz-Ertner Heavy-ion tumor therapy: Physical and radiobiological benefits Rev Mod Phys 82 2010 383 425
8. R. Grün, T. Friedrich, M. Kramer, and et al. Assessment of potential advantages of relevant ions for particle therapy: A model based study Med Phys 42 2015 1037 1047
9. M.L. De Bruin, J. Sparidans, M.B. van't Veer, and et al. Breast cancer risk in female survivors of hodgkin's lymphoma: Lower risk after smaller radiation volumes J Clin Oncol 27 2009 4239 4246
10. F.E. van Leeuwen, W.J. Klokman, M. Stovall, and et al. Roles of radiation dose, chemotherapy, and hormonal factors in breast cancer following hodgkin's disease J Natl Cancer Inst 95 2003 971 980
11. National Research Council Of The National Academies Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2 2006 National Academies Press Washington, DC
12. J.E. Coggle Lung tumour induction in mice after X-rays and neutrons Int J Radiat Biol Relat Stud Phys Chem Med 53 1988 585 597
13. A.C. Upton, V.K. Jenkins, and J.W. Conklin Myeloid leukemia in the mouse Ann N Y Acad Sci 114 1964 189 202
14. T.C. Yang, L.M. Craise, M.T. Mei, and et al. Neoplastic cell transformation by heavy charged particles Radiat Res Suppl 8 1985 S177 S187
15. U. Schneider, M. Sumila, J. Robotka, and et al. Dose-response relationship for breast cancer induction at radiotherapy dose Radiat Oncol 6 2011 67
16. W.D. Newhauser, and M. Durante Assessing the risk of second malignancies after modern radiotherapy Nat Rev Cancer 11 2011 438 448
17. G.W. Barendsen The relationships between RBE and let for different types of lethal damage in mammalian cells: Biophysical and molecular mechanisms Radiat Res 139 1994 257 270
18. R.C. Miller, S.A. Marino, D.J. Brenner, and et al. The biological effectiveness of radon-progeny alpha particles. II. Oncogenic transformation as a function of linear energy transfer Radiat Res 142 1995 54 60
19. E.L. Alpen, P. Powers-Risius, S.B. Curtis, and et al. Tumorigenic potential of high-z, high-let charged-particle radiations Radiat Res 136 1993 382 391
20. T. Friedrich, U. Scholz, T. Elsasser, and et al. Systematic analysis of rbe and related quantities using a database of cell survival experiments with ion beam irradiation Radiat Res 54 2013 494 514
21. F.A. Cucinotta, M.Y. Kim, and L.J. Chappell Probability of causation for space radiation carcinogenesis following international space station, near Earth asteroid, and Mars missions 2012 NASA Houston
22. V.S. Manem, M. Kohandel, D.C. Hodgson, and et al. The effect of radiation quality on the risks of second malignancies Int J Radiat Biol 91 2015 209 217
23. G.M. Dores, C. Metayer, R.E. Curtis, and et al. Second malignant neoplasms among long-term survivors of Hodgkin's disease: A population-based evaluation over 25 years J Clin Oncol 20 2002 3484 3494
24. M. Krämer, O. Jakel, T. Haberer, and et al. Treatment planning for heavy-ion radiotherapy: Physical beam model and dose optimization Phys Med Biol 45 2000 3299 3317
25. M. Krämer, and M. Scholz Treatment planning for heavy-ion radiotherapy: Calculation and optimization of biologically effective dose Phys Med Biol 45 2000 3319 3330
26. M. Scholz, A.M. Kellerer, W. Kraft-Weyrather, and et al. Computation of cell survival in heavy ion beams for therapy - the model and its approximation Radiat Environ Bioph 36 1997 59 66
27. T. Friedrich, U. Scholz, T. Elsasser, and et al. Calculation of the biological effects of ion beams based on the microscopic spatial damage distribution pattern Int J Radiat Biol 88 2012 103 107
28. J.H. Peacock, J.J. Eady, S.M. Edwards, and et al. The intrinsic alpha/beta ratio for human tumour cells: Is it a constant? Int J Radiat Biol 61 1992 479 487
29. J. Yarnold, A. Ashton, J. Bliss, and et al. Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: Long-term results of a randomised trial Radiother Oncol 75 2005 9 17
30. M. Krämer, and M. Scholz Rapid calculation of biological effects in ion radiotherapy Phys Med Biol 51 2006 1959 1970
31. B.S. Hoppe, S. Flampouri, R. Zaiden, and et al. Involved-node proton therapy in combined modality therapy for hodgkin lymphoma: Results of a phase 2 study Int J Radiat Oncol Biol Phys 89 2014 1053 1059
32. R.T. Hoppe, R.H. Advani, W.Z. Ai, and et al. Hodgkin lymphoma J Natl Compr Canc Netw 9 2011 1020 1058
33. M. Krämer, and M. Durante Ion beam transport calculations and treatment plans in particle therapy Eur Phys J D 60 2010 195 202
34. H. Paganetti Late effects from scattered and secondary radiation H. Paganetti, Proton Therapy Physics 2012 CRC Press Boca Raton, FL 555 592
35. U. Schneider, D. Zwahlen, D. Ross, and et al. Estimation of radiation-induced cancer from three-dimensional dose distributions: Concept of organ equivalent dose Int J Radiat Oncol Biol Phys 61 2005 1510 1515
36. N.A. Franken, R. ten Cate, P.M. Krawczyk, and et al. Comparison of RBE values of high-let alpha-particles for the induction of DNA-dsbs, chromosome aberrations and cell reproductive death Radiat Oncol 6 2011 64
37. A. Carabe, M. Moteabbed, N. Depauw, and et al. Range uncertainty in proton therapy due to variable biological effectiveness Phys Med Biol 57 2012 1159 1172
38. A. Dasu, and I. Toma-Dasu Impact of variable RBE on proton fractionation Med Phys 40 2013 011705
39. T. Friedrich, M. Durante, and M. Scholz Particle species dependence of cell survival rbe: Evident and not negligible Acta Oncol 52 2013 589 603
40. R.B. Hawkins A microdosimetric-kinetic theory of the dependence of the RBE for cell death on let Med Phys 25 1998 1157 1170
41. B. Emami, J. Lyman, A. Brown, and et al. Tolerance of normal tissue to therapeutic irradiation Int J Radiat Oncol Biol Phys 21 1991 109 122
42. M. Durante, S. Yamada, K. Ando, and et al. X-rays vs. Carbon-ion tumor therapy: Cytogenetic damage in lymphocytes Int J Radiat Oncol Biol Phys 47 2000 793 798
43. K. Gunzert-Marx, D. Schardt, and R.S. Simon Fast neutrons produced by nuclear fragmentation in treatment irradiations with 12c beam Radiat Prot Dosimetry 110 2004 595 600
44. R. Kaderka, D. Schardt, M. Durante, and et al. Out-of-field dose measurements in a water phantom using different radiotherapy modalities Phys Med Biol 57 2012 5059 5074
45. C. La Tessa, T. Berger, R. Kaderka, and et al. Characterization of the secondary neutron field produced during treatment of an anthropomorphic phantom with X-rays, protons and carbon ions Phys Med Biol 59 2014 2111 2125
46. W.D. Newhauser, J.D. Fontenot, A. Mahajan, and et al. The risk of developing a second cancer after receiving craniospinal proton irradiation Phys Med Biol 54 2009 2277 2291
47. M.P. Little, W.F. Heidenreich, S.H. Moolgavkar, and et al. Systems biological and mechanistic modelling of radiation-induced cancer Radiat Environ Biophys 47 2008 39 47
48. I. Shuryak, P. Hahnfeldt, L. Hlatky, and et al. A new view of radiation-induced cancer: Integrating short- and long-term processes. Part I: Approach Radiat Environ Biophys 48 2009 263 274
49. P. Vineis, A. Schatzkin, and J.D. Potter Models of carcinogenesis: An overview Carcinogenesis 31 2010 1703 1709
50. F.A. Cucinotta, and L.J. Chappell Non-targeted effects and the dose response for heavy ion tumor induction Mutat Res 687 2010 49 53