Prevention effects and possible molecular mechanism of mulberry leaf extract and its formulation on rats with insulin-insensitivity

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Liu, Yan ^a   Li, Xuemei ^b   Xie, Chen ^e   Luo, Xiuzhen ^e   Bao, Yonggang ^d   Wu, Bin ^e   Hu, Yuchi ^b   Zhong, Zhong ^c   Liu, Chang ^e   Li, MinJie ^a  

^a Roche R and D Center (China)   (China)

^b BEIJING INSTITUTE FOR DRUG CONTROL   (China)

^c Beijing Century Benefits Co Ltd   (China)

^d Beijing Pepnoch Co   (China)

^e INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYNOJIRIMYCIN; CHOLESTEROL; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MULBERRY EXTRACT; MULBERRY FENUGREEK CINNAMON CASSIA EXTRACT; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PLANT EXTRACT; PROTECTIVE AGENT; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; HERBACEOUS AGENT;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG FORMULATION; DRUG MECHANISM; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID METABOLISM; LOW DRUG DOSE; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; PLANT LEAF; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCREENING TEST; SIGNAL TRANSDUCTION; TOXICITY TESTING; WESTERN BLOTTING; ANIMAL; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; CINNAMOMUM ZEYLANICUM; DIET RESTRICTION; DRUG EFFECTS; HYPERGLYCEMIA; METABOLISM; MORUS; PLANT SEED; SPRAGUE DAWLEY RAT; TRIGONELLA;

ANIMALS; BLOOD GLUCOSE; CINNAMOMUM ZEYLANICUM; DRUGS, CHINESE HERBAL; FASTING; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MICE; MORUS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; SEEDS; TRIGONELLA;

EID: 84963532864     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152728     Document Type: Article

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