Correction of aberrant imprinting by allele-specific epigenome editing

Clinical Pharmacology and Therapeutics

Volumn 99, Issue 5, 2016, Pages 482-484

  Bashtrykov, P ^a   Kungulovski, G ^a   Jeltsch, A ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

UNTRANSLATED RNA;

ALLELE; ARTICLE; CRISPR CAS SYSTEM; DNA BINDING; DNA METHYLATION; DNA STRAND; EPIGENETICS; GENOME IMPRINTING; HUMAN; PRIORITY JOURNAL; CHROMOSOME DISORDER; GENETIC EPIGENESIS; GENETICS;

ALLELES; CHROMOSOME DISORDERS; CRISPR-CAS SYSTEMS; DNA METHYLATION; EPIGENESIS, GENETIC; EPIGENOMICS; GENOMIC IMPRINTING; HUMANS;

EID: 84962921141     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1002/cpt.295     Document Type: Article

References (5)

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2. Jurkowska R.Z., & Jeltsch A. Genomic imprinting-The struggle of the genders at the molecular level. Angew. Chemie. 52, 13524-13536 (2013).
3. de Groote M.L., Verschure P.J., & Rots M.G. Epigenetic editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes. Nucl. Acids Res. 40, 10596-10613 (2012).
4. Gaj T., Gersbach C.A., & Barbas C.F. 3rd. ZFN, TALEN, and CRISPR/Casbased methods for genome engineering. Trends Biotechnol. 31, 397-405 (2013).
5. Qi, L.S., et al. Repurposing CRISPR as an RNA-guided platform for sequencespecific control of gene expression. Cell 152, 1173-1183 (2013).