Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer

Human Molecular Genetics

Volumn 25, Issue 5, 2016, Pages 1008-1018

  Stacey, Simon N ^a   Kehr, Birte ^a   Gudmundsson, Julius ^a   Zink, Florian ^a   Jonasdottir, Aslaug ^a   Gudjonsson, Sigurjon A ^a   Sigurdsson, Asgeir ^a   Halldorsson, Bjarni V ^a,b   Agnarsson, Bjarni A ^c,d   Benediktsdottir, Kristrun R ^c,d   Aben, Katja K H ^e,f   Vermeulen, Sita H ^f   Cremers, Ruben G ^f   Panadero, Angeles ^g   Helfand, Brian T ^h   Cooper, Phillip R ⁱ   Donovan, Jenny L ^j   Hamdy, Freddie C ^k   Jinga, Viorel ^l   Okamoto, Ichiro ^m   Jonasson, Jon G ^c,d,n   Tryggvadottir, Laufey ⁿ   Johannsdottir, Hrefna ^a   Kristinsdottir, Anna M ^a   Masson, Gisli ^a   Magnusson, Olafur T ^a   Iordache, Paul D ^b   Helgason, Agnar ^a,d   Helgason, Hannes ^a,d   Sulem, Patrick ^a   Gudbjartsson, Daniel F ^a,d   Kong, Augustine ^a   Jonsson, Eirikur ^c,d   Barkardottir, Rosa B ^c,d   Einarsson, Gudmundur V ^c,d   Rafnar, Thorunn ^a   Thorsteinsdottir, Unnur ^a,d   Mates, Ioan N ^l   Neal, David E ^k,o   Catalona, William J ⁱ   Mayordomo, José I ^p   Kiemeney, Lambertus A ^f   Thorleifsson, Gudmar ^a   Stefansson, Kari ^a,d   more..

^a DECODE GENETICS   (Iceland)

^b REYKJAVIK UNIVERSITY   (Iceland)

^c LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^d UNIVERSITY OF ICELAND   (Iceland)

^e Netherlands Comprehensive Cancer Organization   (Netherlands)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^g Hospital Ciudad de Coria   (Spain)

^h NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

ⁱ NORTHWESTERN UNIVERSITY   (United States)

^j UNIVERSITY OF BRISTOL   (United Kingdom)

^k UNIVERSITY OF OXFORD   (United Kingdom)

^l CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^m Universitatsklinik fur Dermatologie   (Austria)

ⁿ ICELANDIC CANCER REGISTRY   (Iceland)

^o UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^p UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROCASPASE 8; RNA ISOFORM; CASP8 PROTEIN, HUMAN; CASPASE 8; RETROPOSON;

ADULT; AGED; ARTICLE; CANCER GENE THERAPY; CANCER PREVENTION; CANCER REGISTRY; CANCER SUSCEPTIBILITY; CHROMOSOME 19; CHROMOSOME 2; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA SEQUENCE; GENE FREQUENCY; GENE INSERTION; GENE MAPPING; GENE REPLICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENOME; GENOTYPE; HUMAN; INTRON; INTRON 8; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NETHERLANDS; PRIORITY JOURNAL; PROSTATE CANCER; QUANTITATIVE TRAIT LOCUS; RANDOMIZED CONTROLLED TRIAL; RETROPOSON; RNA SEQUENCE; RNA SPLICING; SIGNAL TRANSDUCTION; SINE VNTR ALU SUBFAMILY E RETROTRANSPOON; SINGLE NUCLEOTIDE POLYMORPHISM; VARIABLE NUMBER OF TANDEM REPEAT; VIRAL GENE THERAPY; ALLELE; BASAL CELL CARCINOMA; BREAST TUMOR; CLINICAL TRIAL; FEMALE; GENETICS; GENOME-WIDE ASSOCIATION STUDY; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ODDS RATIO; PATHOLOGY; PROSTATIC NEOPLASMS; PROTECTION; SKIN TUMOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; BASE SEQUENCE; BREAST NEOPLASMS; CARCINOMA, BASAL CELL; CASPASE 8; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRONS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; PROTECTIVE FACTORS; RETROELEMENTS; RNA SPLICING; SKIN NEOPLASMS;

EID: 84962875873     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv622     Document Type: Article

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