High burden of diabetic foot infections in the top end of Australia: An emerging health crisis (DEFINE study)

Diabetes Research and Clinical Practice

Volumn 110, Issue 2, 2015, Pages 147-157

  Commons, Robert J ^a,d   Robinson, Claire H ^a   Gawler, David ^a   Davis, Joshua S ^b   Price, Ric N ^a,b,c  

^a ROYAL DARWIN HOSPITAL   (Australia)

^b MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d AUCKLAND CITY HOSPITAL   (New Zealand)

Author keywords

Australia; Diabetes mellitus; Diabetic foot infection; Indigenous; Methicillin resistant Staphylococcus aureus; Pseudomonas aeruginosa

Indexed keywords

ANTIBIOTIC AGENT; HEMOGLOBIN A1C;

ADULT; ARTICLE; AUSTRALIA; CONTROLLED STUDY; DEMOGRAPHY; DIABETIC FOOT; FEMALE; HOSPITAL ADMISSION; HOSPITAL BED; HOSPITALIZATION; HUMAN; INCIDENCE; INDIGENOUS AUSTRALIAN; INDIGENOUS PEOPLE; KNEE AMPUTATION; LIFE EXPECTANCY; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MICROBIOLOGY; PROSPECTIVE STUDY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; COMPLICATION; MIDDLE AGED; NORTHERN TERRITORY; WOUND INFECTION;

DIABETIC FOOT; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NORTHERN TERRITORY; PROSPECTIVE STUDIES; WOUND INFECTION;

EID: 84962868869     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2015.09.016     Document Type: Article

References (57)

1. Whiting D.R., Guariguata L., Weil C., Shaw J. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 2011, 94:311-321.
2. Dunstan D.W., Zimmet P.Z., Welborn T.A., De Courten M.P., Cameron A.J., Sicree R.A., et al. The rising prevalence of diabetes and impaired glucose tolerance: the Australian Diabetes Obesity and Lifestyle Study. Diabetes Care 2002, 25:829-834.
3. Barr E.L.M., Magliano D.J., Zimmet P.Z., Polkinghorne K.R., Atkins R.C., Dunstan D.W., et al. The Australian Diabetes Obesity and Lifestyle Study (AusDiab) 2005 2006, International Diabetes Institute.
4. Magliano D.J., Peeters A., Vos T., Sicree R., Shaw J., Sindall C., et al. Projecting the burden of diabetes in Australia-what is the size of the matter?. Aust N Z J Public Health 2009, 33:540-543.
5. Vos T., Goss J., Begg S., Mann N. Australian Burden of Disease and Injury Study Projected Health Care Costs Report 2004, University of Queensland and AIH.
6. Bergin S.M., Brand C.A., Colman P.G., Campbell D.A. The impact of socio-economic disadvantage on rates of hospital separations for diabetes-related foot disease in Victoria Australia. J Foot Ankle Res 2011, 4:17.
7. Summary of Australian Indigenous Health, 2014 2015, Australian Indigenous HealthInfoNet, Retrieved 1/09/2015 from http://www.healthinfonet.ecu.edu.au/health-facts/summary.
8. Maple-Brown L., Cunningham J., Dunne K., Whitbread C., Howard D., Weeramanthri T., et al. Complications of diabetes in urban Indigenous Australians: the DRUID study. Diabetes Res Clin Pract 2008, 80:455-462.
9. Minges K.E., Zimmet P., Magliano D.J., Dunstan D.W., Brown A., Shaw J.E. Diabetes prevalence and determinants in Indigenous Australian populations: A systematic review. Diabetes Res Clin Pract 2011, 93:139-149.
10. O'Dea K., Cunningham J., Maple-Brown L., Weeramanthri T., Shaw J., Dunbar T., et al. Diabetes and cardiovascular risk factors in urban Indigenous adults: Results from the DRUID study. Diabetes Res Clin Pract 2008, 80:483-489.
11. Lazzarini P.A., Gurr J.M., Rogers J.R., Schox A., Bergin S.M. Diabetes foot disease: the Cinderella of Australian diabetes management?. J Foot Ankle Res 2012, 5:24.
12. Lavery L.A., Armstrong D.G., Wunderlich R.P., Tredwell J., Boulton A.J. Diabetic foot syndrome: evaluating the prevalence and incidence of foot pathology in Mexican Americans and non-Hispanic whites from a diabetes disease management cohort. Diabetes Care 2003, 26:1435-1438.
13. Ramsey S.D., Newton K., Blough D., McCulloch D.K., Sandhu N., Reiber G.E., et al. Incidence, outcomes, and cost of foot ulcers in patients with diabetes. Diabetes Care 1999, 22:382-387.
14. Lipsky B.A., Peters E.J., Senneville E., Berendt A.R., Embil J.M., Lavery L.A., et al. Expert opinion on the management of infections in the diabetic foot. Diabetes Metab Res Rev 2012, 28(Suppl 1):163-178.
15. Epidemiology of lower extremity amputation in centres in Europe North America and East Asia. Br J Surg 2000, 87:328-337. The Global Lower Extremity Amputation Study Group.
16. Steffen C., O'Rourke S. Surgical management of diabetic foot complications: the Far North Queensland profile. Aust N Z J Surg 1998, 68:258-260.
17. Davis W.A., Norman P.E., Bruce D.G., Davis T.M. Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes Study. Diabetologia 2006, 49:2634-2641.
18. Richard J.L., Sotto A., Jourdan N., Combescure C., Vannereau D., Rodier M., et al. Risk factors and healing impact of multidrug-resistant bacteria in diabetic foot ulcers. Diabetes Metab 2008, 34:363-369.
19. Wraight P.R., Lawrence S.M., Campbell D.A., Colman P.G. Creation of a multidisciplinary, evidence based, clinical guideline for the assessment, investigation and management of acute diabetes related foot complications. Diabet Med 2005, 22:127-136.
20. O'Rourke I., Heard S., Treacy J., Gruen R., Whitbread C. Risks to feet in the top end: outcomes of diabetic foot complications. ANZ J Surg 2002, 72:282-286.
21. Quarterly Population Estimates (ERP), by State/Territory, Sex and Age. ABS 2015, Australian Bureau of Statistics, Canberra Retrieved 1/9/2015 from http://www.abs.gov.au/AUSSTATS/abs@.nsf/DetailsPage/3101.0Sep2014?OpenDocument.
22. Lipsky B.A., Berendt A.R., Deery H.G., Embil J.M., Joseph W.S., Karchmer A.W., et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004, 39:885-910.
23. Australian Guidelines to Reduce Health Risks from Drinking Alcohol 2009, National Health and Medical Research Council, NHMRC.
24. Therapeutic Guidelines: Antibiotic. Version 14 2010, Expert Advisory Groups, Therapeutic Guidelines Limited, Melbourne.
25. Zhao Y., Paice J., Murtagh D., Lee H., Guthridge S. Population Estimates for Indigenous Health Zones in the Northern Territory 2007, Department of Health and Community Services.
26. Norman P.E., Schoen D.E., Gurr J.M., Kolybaba M.L. High rates of amputation among Indigenous people in Western Australia. Med J Aust 2010, 192:421.
27. O'Rourke S., Steffen C., Raulli A., Tulip F. Diabetic major amputation in Far North Queensland 1998-2008: what is the gap for Indigenous patients?. Aust J Rural Health 2013, 21:268-273.
28. Squires D.A. The U.S. health system in perspective: a comparison of twelve industrialized nations. Issue Brief (Commonw Fund) 2011, 16:1-14.
29. Lazzarini P.A., O'Rourke S.R., Russell A.W., Derhy P.H., Kamp M.C. Reduced incidence of foot-related hospitalisation and amputation amongst persons with diabetes in Queensland, Australia. PLOS ONE 2015, 10:e0130609.
30. Dillon M.P., Kohler F., Peeva V. Incidence of lower limb amputation in Australian hospitals from 2000 to 2010. Prosthet Orthot Int 2014, 38:122-132.
31. Rayman G., Krishnan S.T., Baker N.R., Wareham A.M., Rayman A. Are we underestimating diabetes-related lower-extremity amputation rates? Results and benefits of the first prospective study. Diabetes Care 2004, 27:1892-1896.
32. Krishnan S., Nash F., Baker N., Fowler D., Rayman G. Reduction in diabetic amputations over 11 years in a defined U.K. population: benefits of multidisciplinary team work and continuous prospective audit. Diabetes Care 2008, 31:99-101.
33. Ebskov L.B. Diabetic amputation and long-term survival. Int J Rehabil Res 1998, 21:403-408.
34. Aulivola B., Hile C.N., Hamdan A.D., Sheahan M.G., Veraldi J.R., Skillman J.J., et al. Major lower extremity amputation: outcome of a modern series. Arch Surg 2004, 139:395-399. discussion; 399.
35. Reiber G.E., Pecoraro R.E., Koepsell T.D. Risk factors for amputation in patients with diabetes mellitus. A case-control study. Ann Intern Med 1992, 117:97-105.
36. Dorresteijn J.A., Kriegsman D.M., Assendelft W.J., Valk G.D. Patient education for preventing diabetic foot ulceration. Cochrane Database Syst Rev 2014, 12:CD001488.
37. McDermott R.A., Tulip F., Schmidt B. Diabetes care in remote northern Australian Indigenous communities. Med J Aust 2004, 180:512-516.
38. Podiatry Registrant Data: June 2015 2015, Podiatry Board of Australia, Australian Health Practitioner Regulation Agency.
39. Patout C.A., Birke J.A., Horswell R., Williams D., Cerise F.P. Effectiveness of a comprehensive diabetes lower-extremity amputation prevention program in a predominantly low-income African-American population. Diabetes Care 2000, 23:1339-1342.
40. Canavan R.J., Unwin N.C., Kelly W.F., Connolly V.M. Diabetes- and nondiabetes-related lower extremity amputation incidence before and after the introduction of better organized diabetes foot care: continuous longitudinal monitoring using a standard method. Diabetes Care 2008, 31:459-463.
41. Lipsky B.A., Aragón-Sánchez J., Diggle M., Embil J., Kono S., Lavery L., et al. IWGDF Guidance on the diagnosis and management of foot infections in persons with diabetes 2015.
42. Gerding D.N. Foot infections in diabetic patients: the role of anaerobes. Clin Infect Dis 1995, 20(Suppl 2):S283-S288.
43. Yates C., May K., Hale T., Allard B., Rowlings N., Freeman A., et al. Wound chronicity, inpatient care, and chronic kidney disease predispose to MRSA infection in diabetic foot ulcers. Diabetes Care 2009, 32:1907-1909.
44. Bowler P.G., Duerden B.I., Armstrong D.G. Wound microbiology and associated approaches to wound management. Clin Microbiol Rev 2001, 14:244-269.
45. Zenelaj B., Bouvet C., Lipsky B.A., Uckay I. Do diabetic foot infections with methicillin-resistant Staphylococcus aureus differ from those with other pathogens?. Int J Low Extrem Wounds 2014, 13:263-272.
46. McDonald M., Dougall A., Holt D., Huygens F., Oppedisano F., Giffard P.M., et al. Use of a single-nucleotide polymorphism genotyping system to demonstrate the unique epidemiology of methicillin-resistant Staphylococcus aureus in remote aboriginal communities. J Clin Microbiol 2006, 44:3720-3727.
47. Tentolouris N., Jude E.B., Smirnof I., Knowles E.A., Boulton A.J. Methicillin-resistant Staphylococcus aureus: an increasing problem in a diabetic foot clinic. Diabet Med 1999, 16:767-771.
48. Tentolouris N., Petrikkos G., Vallianou N., Zachos C., Daikos G.L., Tsapogas P., et al. Prevalence of methicillin-resistant Staphylococcus aureus in infected and uninfected diabetic foot ulcers. Clin Microbiol Infect 2006, 12:186-189.
49. Mackintosh C.L., White H.A., Seaton R.A. Outpatient parenteral antibiotic therapy (OPAT) for bone and joint infections: experience from a UK teaching hospital-based service. J Antimicrob Chemother 2011, 66:408-415.
50. Vardakas K.Z., Horianopoulou M., Falagas M.E. Factors associated with treatment failure in patients with diabetic foot infections: An analysis of data from randomized controlled trials. Diabetes Res Clin Pract 2008, 80:344-351.
51. Acharya S., Soliman M., Egun A., Rajbhandari S.M. Conservative management of diabetic foot osteomyelitis. Diabetes Res Clin Pract 2013, 101:e18-e20.
52. Mantey I., Hill R.L., Foster A.V., Wilson S., Wade J.J., Edmonds M.E. Infection of foot ulcers with Staphylococcus aureus associated with increased mortality in diabetic patients. Commun Dis Public Health 2000, 3:288-290.
53. Illgner U., Uekoetter A., Runge S., Wetz H.H. Infections with Pseudomonas aeruginosa in Charcot arthropathy of the foot. Foot Ankle Int 2013, 34:234-237.
54. Lipsky B.A., Tabak Y.P., Johannes R.S., Vo L., Hyde L., Weigelt J.A. Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost. Diabetologia 2010, 53:914-923.
55. Goldufsky J., Wood S.J., Jayaraman V., Majdobeh O., Chen L., Qin S., et al. Pseudomonas aeruginosa uses T3SS to inhibit diabetic wound healing. Wound Repair Regen 2015.
56. Zhao Y., Condon J.R., Guthridge S., You J. Living longer with a greater health burden-changes in the burden of disease and injury in the Northern Territory Indigenous population between 1994-1998 and 1999-2003. Aust N Z J Public Health 2010, 34(Suppl 1):S93-S98.
57. Andreasyan K., Hoy W.E. Recent patterns in chronic disease mortality in remote living Indigenous Australians. BMC Public Health 2010, 10:483.