Occupational Exposure to Multi-Walled Carbon Nanotubes during Commercial Production Synthesis and Handling

Annals of Occupational Hygiene

Volumn 60, Issue 3, 2016, Pages 305-317

  Kuijpers, Eelco ^a   Bekker, Cindy ^a,b   Fransman, Wouter ^a   Brouwer, Derk ^a   Tromp, Peter ^a   Vlaanderen, Jelle ^b   Godderis, Lode ^c,d   Hoet, Peter ^c   Lan, Qing ^e   Silverman, Debra ^e   Vermeulen, Roel ^b   Pronk, Anjoeka ^a  

^a TNO   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d DEWE   (Belgium)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Commercial production; multi walled carbon nanotubes; occupational exposur

Indexed keywords

CARBON NANOTUBES; NANOTUBES; YARN;

COMMERCIAL PRODUCTIONS; CONFIDENCE LIMIT; LOWER CONFIDENCE LIMIT; OCCUPATIONAL EXPOSUR; OCCUPATIONAL EXPOSURE; PERSONAL EXPOSURES; POWDER CONDITIONING; SPECIFIC ACTIVITY;

MULTIWALLED CARBON NANOTUBES (MWCN);

AIR POLLUTANT; CARBON NANOTUBE;

AIR POLLUTANT; ANALYSIS; CHEMISTRY; ENVIRONMENTAL MONITORING; EXPOSURE; HUMAN; LUNG; OCCUPATIONAL EXPOSURE; PARTICLE SIZE; PROCEDURES; SCANNING ELECTRON MICROSCOPY;

AIR POLLUTANTS, OCCUPATIONAL; ENVIRONMENTAL MONITORING; HUMANS; INHALATION EXPOSURE; LUNG; MICROSCOPY, ELECTRON, SCANNING; NANOTUBES, CARBON; OCCUPATIONAL EXPOSURE; PARTICLE SIZE;

EID: 84962663639     PISSN: 00034878     EISSN: 14753162     Source Type: Journal    
DOI: 10.1093/annhyg/mev082     Document Type: Article

References (42)

1. Bekker C, Kuijpers E, Brouwer DH et al. (2015) Occupational exposure to nano-objects and their agglomerates and aggregates across various life cycle stages: a broad-scale exposure study. Ann Occup Hyg; 59: 681-704.
2. Bello D (2009) Exposure to nanoscale particles and fibers during machining of hybrid advanced composites containing carbon nanotubes. J Nanoparticle Res; 11: 231-49.
3. Bello D, Hart AJ, Hallock M et al. (2008) Particle exposure levels during CVD growth and subsequent handling of vertically-aligned carbon nanotube films. Carbon; 166: 974-81.
4. Bello D, Wardle BL, Zhang J et al. (2010) Characterization of exposures to nanoscale particles and fibers during solid core drilling of hybrid carbon nanotube advanced composites. Int J Occup Environ Health; 16: 434-50.
5. Brouwer D, Berges M, Virji MA et al. (2012) Harmonization of measurement strategies for exposure to manufactured nanoobjects; Report of a workshop. Ann Occup Hyg; 56: 1-9.
6. Castranova V, Schulte PA, Zumwalde RD. (2013) Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers. Accounts Chem Res; 46: 642-49.
7. CEN. (1993) (ed) Size Fraction Definition for Measurement of Airborne Particles, European Standard EN 481, CEN European Committee for Standardization, rue de Stassart 36, B-1050, Brussels, Belgium.
8. Dahm MM, Evans DE, Schubauerberigan MK et al. (2012) Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers. Ann Occup Hyg; 56: 542-56.
9. Dahm MM, Schubauer-Berigan MK, Evans DE et al. (2015) Carbon nanotube and nanofiber exposure assessments: An analysis of 14 site visits. Ann Occup Hyg; 59: 705-23.
10. Fleury D, Bomfim JAS, Vignes A et al. (2013) Identification of the main exposure scenarios in the production of CNTpolymer nanocomposites by melt-moulding process. J Cleaner Prod; 53: 22-36.
11. Grosse Y, Loomis D, Guyton KZ et al. on behalf of IARC. (2014) Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes. Lancet Oncol; 15: 1427-28.
12. Ham S, Yoon C, Lee E et al. (2012) Task-based exposure assessment of nanoparticles in the workplace. J Nanoparticle Res; 14: 9.
13. Han JH, Lee EJ, Lee JH et al. (2008) Monitoring multiwalled carbon nanotube exposure in carbon nanotube research facility. Inhalation Toxicol; 20: 741-49.
14. Hedmer M, Isaxon C, Nilsson PT et al. (2014) Exposure and emission measurements during production, purification, and functionalization of arc-discharge-produced multi-walled carbon nanotubes. Ann Occup Hyg; 58: 355-79.
15. Hubbs A, Mercer R, Coad J et al. (2009) Persistent pulmonary inflammation, airway mucous metaplasia, and migration of multi-walled carbon nanotubes from the lung after subchronic exposure. The Toxicologist; 108: A2193.
16. Invernizzi N. (2011) Nanotechnology between the lab and the shop floor: What are the effects on labor? J Nanoparticle Res; 13: 2249-68.
17. Johnson DR, Methner MM, Kennedy AJ et al. (2010) Potential for occupational exposure to engineered carbon-based nanomaterials in environmental laboratory studies. Environ Health Perspect; 118: 49-54.
18. Lee JH, Lee S, Bae GN et al. (2010) Exposure assessment of carbon nanotube manufacturing workplaces. Inhal Toxicol; 22: 369-81.
19. Maynard AD, Baron PA, Foley M et al. (2004) Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material. J Toxicol Environ Health; 67: 87-107.
20. Mercer RR, Hubbs AF, Scabilloni JF et al. (2011) Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes. Particle Fibre Toxicol; 8: 21.
21. Mercer RR, Hubbs AF, Scabilloni JF et al. (2010) Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes. Particle and Fibre Toxicol; 7: 28.
22. Methner M, Beaucham C, Crawford C et al. (2012) Field application of the nanoparticle emission assessment technique (NEAT): Task-based air monitoring during the processing of engineered nanomaterials (ENM) at four facilities. J Occup Environ Hyg; 9: 543-55.
23. Methner M, Hodson L, Dames A et al. (2010) Nanoparticle Emission Assessment Technique (NEAT) for the identification and measurement of potential inhalation exposure to engineered nanomaterials-Part B: Results from 12 field studies. J Occup Environ Hyg; 7: 163-76.
24. NIOSH. (2013) Occupational exposure to carbon nanotubes and nanofibers. Curr Intell Bull; 65.
25. Nowack B, David RM, Fissan H et al. (2013) Review: Potential release scenarios for carbon nanotubes used in composites. Environ Int; 59: 1-11.
26. Ogura I, Sakurai H, Mizuno K et al. (2011) Release potential of single-wall carbon nanotubes produced by super-growth method during manufacturing and handling. J Nanoparticle Res 13: 1265-80.
27. Ono-Ogasawara M, Myojo T. (2011) A proposal of method for evaluating airborne MWCNT concentration. Ind Health; 49: 726-34.
28. Ono-Ogasawara M, Myojo T. (2013) Characteristics of multiwalled carbon nanotubes and background aerosols by carbon analysis; particle size and oxidation temperature. Adv Powder Technol; 24: 263-9.
29. Porter D, Wolfarth M, Chen B et al. (2009) Pulmonary toxicity of inhaled multi-walled carbon nanotubes. The Toxicologist; 108: A2193.
30. Porter DW, Hubbs AF, Mercer RR et al. (2010) Mouse pulmonary dose-and time course-responses induced by exposure to multi-walled carbon nanotubes. Toxicology; 269: 136-47.
31. Pauluhn J. (2010) Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol Sci; 113: 226-42.
32. Poland CA, Duffin R, Kinloch I et al. (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat. Nanotechnol; 3: 423-28.
33. Rappaport SM, Weavers M, Taylors D et al. (1999) Application of mixed models to assess exposures, monitored by construction workers during hot processes. Ann Occup Hyg; 43: 457-69.
34. Sansone EB, Bernard T. (1976) Particle collection by probes of nil and infinite bluntness, Atmos Environ; 10: 577-81.
35. Sargent LM, Porter DW, Staska LM et al. (2014) Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes. Particle Fibre Toxicol; 11: 1.
36. Takaya M, Ono-Ogasawara M, Shinohara Y et al. (2012) Evaluation of exposure risk in the weaving process of MWCNT-coated yarn with real-time particle concentration measurements and characterization of dust particles. Ind Health; 50: 147-55.
37. Tromp PC, Bekker C, Kuijpers E, Jedynska AD, Pronk A. A new approach to combine analytical methods for workplace exposure assessment to airborne MWCNT (in preparation).
38. Tsai S, Hofmann M, Hallock M, et al. (2009) Characterization and evaluation of nanoparticle release during the synthesis of single-walled and multiwalled carbon nanotubes by chemical vapor deposition. Environ Sci Technol; 43: 6017-23.
39. Vincent JH. (1989) Aerosol sampling, science and practice. John Wiley & Sons Ltd. ISBN: 0471921750.
40. Wang J, Pui DYH. (2011) Characterization, exposure measurement and control for nanoscale particles in workplaces and on the road. J Phys Confer Series; 304: 012008.
41. Wolfarth M, Porter D, Hubbs A et al. (2009) Pulmonary toxicity of multi-walled carbon nanotubes.The Toxicologist; 108: A2196.
42. Yeganeh B, Kull CM, Hull MS et al. (2008) Characterization of airborne particles during production of carbonaceous nanomaterials. Environ Sci Technol; 42: 4600-6