Human acetyl-CoA:glucosamine-6-phosphate N -acetyltransferase 1 has a relaxed donor specificity and transfers acyl groups up to four carbons in length

Biochemistry and Cell Biology

Volumn 94, Issue 2, 2016, Pages 197-204

  Brockhausen, Inka ^a   Nair, Dileep G ^a,b   Chen, Min ^a,c   Yang, Xiaojing ^a   Allingham, John S ^a   Szarek, Walter A ^a   Anastassiades, Tassos ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b Ministry of Higher Education Sultanate of Oman   (Oman)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Acetyl CoA binding; Butyryl CoA; Fluorescence assays; GlcNBu; Hs GNA1; Radioactive assays; Site directed mutagenesis

Indexed keywords

BIOCHEMISTRY; CARTILAGE; ENZYME ACTIVITY; FLUORESCENCE; MEDICAL APPLICATIONS; RADIOACTIVITY;

ACETYL-COA; BUTYRYL-COA; FLUORESCENCE ASSAY; GLCNBU; HS GNA1; SITE DIRECTED MUTAGENESIS;

GLUCOSAMINE;

ACETYL COENZYME A; ACETYL GROUP; AMINO ACID; BUTYL GROUP; BUTYRYL COENZYME A; COENZYME A; DECANOYL COENZYME A; FUNCTIONAL GROUP; GLUCOSAMINE PHOSPHATE ACETYLTRANSFERASE; ISOBUTYRYL COENZYME A; ISOBUTYRYL GROUP; ISOVALERYL COENZYME A; MUTANT PROTEIN; PROPIONYL COENZYME A; PROPIONYL GROUP; UNCLASSIFIED DRUG; CARBON; GLUCOSAMINE; GLUCOSAMINE 6-PHOSPHATE; GLUCOSE 6 PHOSPHATE; GNPNAT1 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; FLUORESCENCE ANALYSIS; MOLECULAR MODEL; POLYACRYLAMIDE GEL ELECTROPHORESIS; RADIOACTIVITY; SITE DIRECTED MUTAGENESIS; SPECTROPHOTOMETRY; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMISTRY; FLUORESCENCE; GENETICS; HUMAN; METABOLISM;

ACETYL COENZYME A; CARBON; FLUORESCENCE; GLUCOSAMINE; GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE; GLUCOSE-6-PHOSPHATE; HUMANS; SPECTROPHOTOMETRY;

EID: 84962376906     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/bcb-2015-0115     Document Type: Article

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