Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in diabetes prevention program participants

Diabetes

Volumn 65, Issue 2, 2016, Pages 520-526

  Hivert, Marie France ^a,b,c   Christophi, Costas A ^d   Franks, Paul W ^e,f,g   Jablonski, Kathleen A ^d   Ehrmann, David A ^h   Kahn, Steven E ⁱ   Horton, Edward S ^a,j   Pollin, Toni I ^k   Mather, Kieren J ^l   Perreault, Leigh ^m   Barrett Connor, Elizabeth ⁿ   Knowler, William C ^o   Florez, Jose C ^a,b,p  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

^d GEORGE WASHINGTON UNIVERSITY   (United States)

^e LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g UMEÅ UNIVERSITY   (Sweden)

^h UNIVERSITY OF CHICAGO   (United States)

ⁱ UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^j JOSLIN DIABETES CENTER   (United States)

^k UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^l INDIANA UNIVERSITY   (United States)

^m UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^p BROAD INSTITUTE OF MIT AND HARVARD   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; METFORMIN; PLACEBO; ANTIDIABETIC AGENT;

ADULT; AGE DISTRIBUTION; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ETHNICITY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HEREDITY; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; WAIST CIRCUMFERENCE; CLINICAL TRIAL; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; UNITED STATES;

ADULT; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MALE; METFORMIN; MIDDLE AGED; RISK ASSESSMENT; RISK FACTORS; RISK REDUCTION BEHAVIOR; UNITED STATES;

EID: 84962362095     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0950     Document Type: Article

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