Alleviation of renal mitochondrial dysfunction and apoptosis underlies the protective effect of sitagliptin in gentamicin-induced nephrotoxicity

Journal of Pharmacy and Pharmacology

Volumn 68, Issue 4, 2016, Pages 523-532

  Abuelezz, Sally A ^a   Hendawy, Nevien ^a   Abdel Gawad, Sara ^a  

^a AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

apoptosis; gentamicin; mitochondrial dysfunction; nephrotoxicity; oxidative stress; sitagliptin

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CATALASE; CREATININE; CYTOCHROME C OXIDASE; GENTAMICIN; GLUCOSE; GLUTATHIONE; MALONALDEHYDE; NITROGEN; PROTEIN BAX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SITAGLIPTIN; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UREA; ANTIOXIDANT; APOPTOSIS REGULATORY PROTEIN; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY MITOCHONDRION; KIDNEY TUBULE DAMAGE; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NEPHROTOXICITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN URINE LEVEL; RAT; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL; URINARY EXCRETION; ANIMAL; BLOOD; CELL PROTECTION; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; ELECTRON TRANSPORT; ENERGY METABOLISM; KIDNEY; KIDNEY DISEASES; MALE; METABOLISM; PATHOLOGY; PROTEINURIA; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOMARKERS; BLOOD GLUCOSE; BLOOD UREA NITROGEN; CREATININE; CYTOPROTECTION; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT; ENERGY METABOLISM; GENTAMICINS; KIDNEY; KIDNEY DISEASES; LIPID PEROXIDATION; MALE; MITOCHONDRIA; OXIDATIVE STRESS; PROTEINURIA; RATS, WISTAR; SITAGLIPTIN PHOSPHATE;

EID: 84962280045     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12534     Document Type: Article

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