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Volumn 7, Issue 3, 2016, Pages 2780-2795

In silico pathway analysis in cervical carcinoma reveals potential new targets for treatment

Author keywords

Cancer; Cervical carcinoma; In silico pathway analysis; Treatment targets

Indexed keywords

BIOLOGICAL MARKER; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; MYC PROTEIN; MYC PROTEIN, HUMAN; TUMOR MARKER;

EID: 84962243966     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6667     Document Type: Article
Times cited : (22)

References (45)
  • 2
    • 59349121140 scopus 로고    scopus 로고
    • Papillomaviruses in the causation of human cancers-a brief historical account
    • Hausen zur H. Papillomaviruses in the causation of human cancers-a brief historical account. Virology. 2009; 384:260-5.
    • (2009) Virology , vol.384 , pp. 260-265
    • Hausen zur, H.1
  • 4
    • 84924939973 scopus 로고    scopus 로고
    • Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers
    • Xiang L, Li J, Jiang W, Shen X, Yang W, Wu X, Yang H. Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers. Oncotarget. 2015; 6:4968-75. doi:10.18632/oncotarget.3212.
    • (2015) Oncotarget , vol.6 , pp. 4968-4975
    • Xiang, L.1    Li, J.2    Jiang, W.3    Shen, X.4    Yang, W.5    Wu, X.6    Yang, H.7
  • 6
    • 0027958101 scopus 로고
    • Demonstration and characterization of the angiogenic properties of cervical dysplasia
    • Smith-McCune KK, Weidner N. Demonstration and characterization of the angiogenic properties of cervical dysplasia. Cancer Res. 1994; 54:800-4.
    • (1994) Cancer Res , vol.54 , pp. 800-804
    • Smith-McCune, K.K.1    Weidner, N.2
  • 10
    • 84941979047 scopus 로고    scopus 로고
    • Genomic landscape of human papillomavirus-associated cancers
    • Rusan M, Li YY, Hammerman PS. Genomic landscape of human papillomavirus-associated cancers. Clin Cancer Res. 2015; 21:2009-19.
    • (2015) Clin Cancer Res , vol.21 , pp. 2009-2019
    • Rusan, M.1    Li, Y.Y.2    Hammerman, P.S.3
  • 15
    • 0036781812 scopus 로고    scopus 로고
    • c-MYC: more than just a matter of life and death
    • Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002; 2:764-76.
    • (2002) Nat Rev Cancer , vol.2 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 19
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells
    • Marks PA, Richon VM. Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst. 2000; 92:1210-1216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2
  • 20
    • 1542514783 scopus 로고    scopus 로고
    • Targeted histone deacetylase inhibition for cancer therapy
    • Vigushin DM, Coombes RC. Targeted histone deacetylase inhibition for cancer therapy. Curr Cancer Drug Targets. 2004; 4:205-18.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 205-218
    • Vigushin, D.M.1    Coombes, R.C.2
  • 21
    • 0033634869 scopus 로고    scopus 로고
    • E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control
    • Gaubatz S, Lindeman GJ, Ishida S, Jakoi L, Nevins JR. E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell. 2000; 6:729-35.
    • (2000) Mol Cell , vol.6 , pp. 729-735
    • Gaubatz, S.1    Lindeman, G.J.2    Ishida, S.3    Jakoi, L.4    Nevins, J.R.5
  • 22
    • 84901306391 scopus 로고    scopus 로고
    • E2F inhibition synergizes with paclitaxel in lung cancer cell lines
    • Kurtyka CA, Chen L, Cress WD. E2F inhibition synergizes with paclitaxel in lung cancer cell lines. PLoS ONE. 2014; 9:e96357.
    • (2014) PLoS ONE , vol.9
    • Kurtyka, C.A.1    Chen, L.2    Cress, W.D.3
  • 23
    • 84863214272 scopus 로고    scopus 로고
    • Anticancer drugs: Reactivating p53
    • Harrison C. Anticancer drugs: Reactivating p53. Nat Rev Drug Discov. 2012; 11:517.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 517
    • Harrison, C.1
  • 24
    • 84884183730 scopus 로고    scopus 로고
    • Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes
    • Altomare D, Velidandla R, Pirisi L, Creek KE. Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes. BMC Cancer. 2013; 13:424.
    • (2013) BMC Cancer , vol.13 , pp. 424
    • Altomare, D.1    Velidandla, R.2    Pirisi, L.3    Creek, K.E.4
  • 26
    • 77953366381 scopus 로고    scopus 로고
    • Expression and mutational analysis of TGF-beta/Smads signaling in human cervical cancers
    • Ki K-D, Tong S-Y, Huh C-Y, Lee J-M, Lee S-K, Chi S-G. Expression and mutational analysis of TGF-beta/Smads signaling in human cervical cancers. J Gynecol Oncol. 2009; 20:117-21.
    • (2009) J Gynecol Oncol , vol.20 , pp. 117-121
    • Ki, K.-D.1    Tong, S.-Y.2    Huh, C.-Y.3    Lee, J.-M.4    Lee, S.-K.5    Chi, S.-G.6
  • 29
    • 0035915771 scopus 로고    scopus 로고
    • Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer
    • Birner P, Schindl M, Obermair A, Breitenecker G, Kowalski H, Oberhuber G. Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer. Int J Cancer. 2001; 95:29-33.
    • (2001) Int J Cancer , vol.95 , pp. 29-33
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Breitenecker, G.4    Kowalski, H.5    Oberhuber, G.6
  • 30
    • 33745058978 scopus 로고    scopus 로고
    • Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia-and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells
    • Zhang Q, Tang X, Lu Q, Zhang Z, Rao J, Le AD. Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia-and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. Mol Cancer Ther. 2006; 5:1227-38.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1227-1238
    • Zhang, Q.1    Tang, X.2    Lu, Q.3    Zhang, Z.4    Rao, J.5    Le, A.D.6
  • 32
    • 84885343036 scopus 로고    scopus 로고
    • Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer
    • Siegfried Z, Bonomi S, Ghigna C, Karni R. Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer. Int J Cell Biol. 2013; 2013:568931.
    • (2013) Int J Cell Biol , vol.2013
    • Siegfried, Z.1    Bonomi, S.2    Ghigna, C.3    Karni, R.4
  • 34
    • 33645226001 scopus 로고    scopus 로고
    • Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation
    • Bertelsen BI, Steine SJ, Sandvei R, Molven A, Laerum OD. Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation. Int J Cancer. 2006; 118:1877-83.
    • (2006) Int J Cancer , vol.118 , pp. 1877-1883
    • Bertelsen, B.I.1    Steine, S.J.2    Sandvei, R.3    Molven, A.4    Laerum, O.D.5
  • 36
    • 84873060939 scopus 로고    scopus 로고
    • Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis
    • Wu S, Shang H, Cui L, Zhang Z, Zhang Y, Li Y, Wu J, Li R-K, Xie J. Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis. Mol Cell Biochem. 2013; 375:69-79.
    • (2013) Mol Cell Biochem , vol.375 , pp. 69-79
    • Wu, S.1    Shang, H.2    Cui, L.3    Zhang, Z.4    Zhang, Y.5    Li, Y.6    Wu, J.7    Li, R.-K.8    Xie, J.9
  • 38
    • 34548526743 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, Part I: Covalent histone modifications
    • Wang GG, Allis CD, Chi P. Chromatin remodeling and cancer, Part I: Covalent histone modifications. Trends Mol Med. 2007; 13:363-72.
    • (2007) Trends Mol Med , vol.13 , pp. 363-372
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 40
    • 84891933728 scopus 로고    scopus 로고
    • The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle
    • Ichim G, Mola M, Finkbeiner MG, Cros M-P, Herceg Z, Hernandez-Vargas H. The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle. Oncogene. 2014; 33:181-92.
    • (2014) Oncogene , vol.33 , pp. 181-192
    • Ichim, G.1    Mola, M.2    Finkbeiner, M.G.3    Cros, M.-P.4    Herceg, Z.5    Hernandez-Vargas, H.6
  • 42
    • 54949123382 scopus 로고    scopus 로고
    • Second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathway
    • Perez-Plasencia C, Dueñas-Gonzalez A, Alatorre-Tavera B. Second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathway. Int Arch Med. 2008;1:10.
    • (2008) Int Arch Med , vol.1 , pp. 10
    • Perez-Plasencia, C.1    Dueñas-Gonzalez, A.2    Alatorre-Tavera, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.