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Volumn 11, Issue 5, 2016, Pages 619-629

Reduction in Hepatocyte Growth Factor Serum Levels is Associated with Improved Prognosis in Advanced Lung Adenocarcinoma Patients Treated with Afatinib: a Phase II Trial

Author keywords

[No Author keywords available]

Indexed keywords

AFATINIB; SCATTER FACTOR; VASCULOTROPIN RECEPTOR; QUINAZOLINE DERIVATIVE; RADIOSENSITIZING AGENT;

EID: 84962197460     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-016-0425-x     Document Type: Article
Times cited : (15)

References (54)
  • 1
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
    • COI: 1:CAS:528:DC%2BC2cXitVyktbzI
    • Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer J Int Cancer. 2015;136(5):E359–86. doi:10.1002/ijc.29210.
    • (2015) Int J Cancer J Int Cancer , vol.136 , Issue.5 , pp. E359-E386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3    Eser, S.4    Mathers, C.5    Rebelo, M.6
  • 2
    • 84863856184 scopus 로고    scopus 로고
    • Clinical and pathological characteristics, outcome and mutational profiles regarding non-small-cell lung cancer related to wood-smoke exposure
    • COI: 1:CAS:528:DC%2BC38Xhtlers7vP
    • Arrieta O, Campos-Parra AD, Zuloaga C, Aviles A, Sanchez-Reyes R, Manriquez ME, et al. Clinical and pathological characteristics, outcome and mutational profiles regarding non-small-cell lung cancer related to wood-smoke exposure. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2012;7(8):1228–34. doi:10.1097/JTO.0b013e3182582a93.
    • (2012) J Thorac Oncol Off Publ Int Assoc Study Lung Cancer , vol.7 , Issue.8 , pp. 1228-1234
    • Arrieta, O.1    Campos-Parra, A.D.2    Zuloaga, C.3    Aviles, A.4    Sanchez-Reyes, R.5    Manriquez, M.E.6
  • 3
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC lung cancer staging project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
    • Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R, et al. The IASLC lung cancer staging project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2007;2(8):706–14. doi:10.1097/JTO.0b013e31812f3c1a.
    • (2007) J Thorac Oncol Off Publ Int Assoc Study Lung Cancer , vol.2 , Issue.8 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3    Giroux, D.J.4    Groome, P.A.5    Rami-Porta, R.6
  • 6
    • 78649280568 scopus 로고    scopus 로고
    • The emerging role of epidermal growth factor receptor (EGFR) inhibitors in first-line treatment for patients with advanced non-small cell lung cancer positive for EGFR mutations
    • COI: 1:CAS:528:DC%2BC3cXhsFyrs7nI, PID: 21789142
    • Okamoto I, Mitsudomi T, Nakagawa K, Fukuoka M. The emerging role of epidermal growth factor receptor (EGFR) inhibitors in first-line treatment for patients with advanced non-small cell lung cancer positive for EGFR mutations. Ther Adv Med Oncol. 2010;2(5):301–7. doi:10.1177/1758834010370698.
    • (2010) Ther Adv Med Oncol , vol.2 , Issue.5 , pp. 301-307
    • Okamoto, I.1    Mitsudomi, T.2    Nakagawa, K.3    Fukuoka, M.4
  • 7
    • 75449110368 scopus 로고    scopus 로고
    • The role of EGFR inhibition in the treatment of non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BC3cXjt1eqsg%3D%3D, PID: 19892771
    • Ray M, Salgia R, Vokes EE. The role of EGFR inhibition in the treatment of non-small cell lung cancer. Oncologist. 2009;14(11):1116–30. doi:10.1634/theoncologist.2009-0054.
    • (2009) Oncologist , vol.14 , Issue.11 , pp. 1116-1130
    • Ray, M.1    Salgia, R.2    Vokes, E.E.3
  • 8
    • 52649131951 scopus 로고    scopus 로고
    • Lung cancer
    • COI: 1:CAS:528:DC%2BD1cXhtFKjt7bM, PID: 18815398
    • Herbst RS, Heymach JV, Lippman SM. Lung cancer. N Engl J Med. 2008;359(13):1367–80. doi:10.1056/NEJMra0802714.
    • (2008) N Engl J Med , vol.359 , Issue.13 , pp. 1367-1380
    • Herbst, R.S.1    Heymach, J.V.2    Lippman, S.M.3
  • 9
    • 79960702788 scopus 로고    scopus 로고
    • Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS)
    • COI: 1:CAS:528:DC%2BC3MXhtVOqsLnO
    • Fukuoka M, Wu YL, Thongprasert S, Sunpaweravong P, Leong SS, Sriuranpong V, et al. Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS). J Clin Oncol Off J Am Soc Clin Oncol. 2011;29(21):2866–74. doi:10.1200/JCO.2010.33.4235.
    • (2011) J Clin Oncol Off J Am Soc Clin Oncol , vol.29 , Issue.21 , pp. 2866-2874
    • Fukuoka, M.1    Wu, Y.L.2    Thongprasert, S.3    Sunpaweravong, P.4    Leong, S.S.5    Sriuranpong, V.6
  • 10
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • COI: 1:CAS:528:DC%2BD1MXhtVygsbfK, PID: 19692680
    • Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, Saijo N, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361(10):947–57. doi:10.1056/NEJMoa0810699.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3    Yang, C.H.4    Chu, D.T.5    Saijo, N.6
  • 11
    • 84937513065 scopus 로고    scopus 로고
    • Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6
    • COI: 1:CAS:528:DC%2BC2MXhtVSgt7%2FP, PID: 26051236
    • Yang JC, Sequist LV, Geater SL, Tsai CM, Mok TS, Schuler M, et al. Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6. Lancet Oncol. 2015;16(7):830–8. doi:10.1016/S1470-2045(15)00026-1.
    • (2015) Lancet Oncol , vol.16 , Issue.7 , pp. 830-838
    • Yang, J.C.1    Sequist, L.V.2    Geater, S.L.3    Tsai, C.M.4    Mok, T.S.5    Schuler, M.6
  • 12
  • 13
    • 84922466166 scopus 로고    scopus 로고
    • The impact of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer
    • PID: 25558790
    • Arrieta O, Cardona AF, Corrales L, Campos-Parra AD, Sanchez-Reyes R, Amieva-Rivera E, et al. The impact of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer. Lung Cancer. 2015;87(2):169–75. doi:10.1016/j.lungcan.2014.12.009.
    • (2015) Lung Cancer , vol.87 , Issue.2 , pp. 169-175
    • Arrieta, O.1    Cardona, A.F.2    Corrales, L.3    Campos-Parra, A.D.4    Sanchez-Reyes, R.5    Amieva-Rivera, E.6
  • 14
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • COI: 1:CAS:528:DC%2BD2MXhsFCiurk%3D, PID: 15728811
    • Kobayashi S, Boggon TJ, Dayaram T, Janne PA, Kocher O, Meyerson M, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med. 2005;352(8):786–92. doi:10.1056/NEJMoa044238.
    • (2005) N Engl J Med , vol.352 , Issue.8 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3    Janne, P.A.4    Kocher, O.5    Meyerson, M.6
  • 15
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • PID: 15737014
    • Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med. 2005;2(3):e73. doi:10.1371/journal.pmed.0020073.
    • (2005) PLoS Med , vol.2 , Issue.3
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3    Riely, G.J.4    Somwar, R.5    Zakowski, M.F.6
  • 16
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • PID: 21430269
    • Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med. 2011;3(75):75ra26. doi:10.1126/scitranslmed.3002003.
    • (2011) Sci Transl Med , vol.3 , Issue.75 , pp. 75ra26
    • Sequist, L.V.1    Waltman, B.A.2    Dias-Santagata, D.3    Digumarthy, S.4    Turke, A.B.5    Fidias, P.6
  • 17
    • 84896720813 scopus 로고    scopus 로고
    • Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer
    • COI: 1:CAS:528:DC%2BC2cXivVejtLg%3D
    • Canadas I, Rojo F, Taus A, Arpi O, Arumi-Uria M, Pijuan L, et al. Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer. Clin Cancer Res Off J Am Assoc Cancer Res. 2014;20(4):938–50. doi:10.1158/1078-0432.CCR-13-1330.
    • (2014) Clin Cancer Res Off J Am Assoc Cancer Res , vol.20 , Issue.4 , pp. 938-950
    • Canadas, I.1    Rojo, F.2    Taus, A.3    Arpi, O.4    Arumi-Uria, M.5    Pijuan, L.6
  • 18
    • 0030877562 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: in vitro analysis of tumor-stromal interactions
    • COI: 1:CAS:528:DyaK2sXkvFKqurg%3D, PID: 9242465
    • Nakamura T, Matsumoto K, Kiritoshi A, Tano Y, Nakamura T. Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: in vitro analysis of tumor-stromal interactions. Cancer Res. 1997;57(15):3305–13.
    • (1997) Cancer Res , vol.57 , Issue.15 , pp. 3305-3313
    • Nakamura, T.1    Matsumoto, K.2    Kiritoshi, A.3    Tano, Y.4    Nakamura, T.5
  • 19
    • 73649102105 scopus 로고    scopus 로고
    • Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
    • COI: 1:CAS:528:DC%2BC3cXkvFKgs7Y%3D, PID: 20129249
    • Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell. 2010;17(1):77–88. doi:10.1016/j.ccr.2009.11.022.
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 77-88
    • Turke, A.B.1    Zejnullahu, K.2    Wu, Y.L.3    Song, Y.4    Dias-Santagata, D.5    Lifshits, E.6
  • 20
    • 56449089812 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations
    • COI: 1:CAS:528:DC%2BD1cXhtlOmt7jE, PID: 19010923
    • Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, et al. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. Cancer Res. 2008;68(22):9479–87. doi:10.1158/0008-5472.CAN-08-1643.
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9479-9487
    • Yano, S.1    Wang, W.2    Li, Q.3    Matsumoto, K.4    Sakurama, H.5    Nakamura, T.6
  • 21
    • 84895766506 scopus 로고    scopus 로고
    • Afatinib: a review of its use in the treatment of advanced non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BC2cXitVyjs70%3D, PID: 24435321
    • Keating GM. Afatinib: a review of its use in the treatment of advanced non-small cell lung cancer. Drugs. 2014;74(2):207–21. doi:10.1007/s40265-013-0170-8.
    • (2014) Drugs , vol.74 , Issue.2 , pp. 207-221
    • Keating, G.M.1
  • 22
    • 79952704441 scopus 로고    scopus 로고
    • EGFR inhibitors in non-small cell lung cancer (NSCLC): the emerging role of the dual irreversible EGFR/HER2 inhibitor BIBW 2992
    • PID: 20574858
    • Spicer JF, Rudman SM. EGFR inhibitors in non-small cell lung cancer (NSCLC): the emerging role of the dual irreversible EGFR/HER2 inhibitor BIBW 2992. Target Oncol. 2010;5(4):245–55. doi:10.1007/s11523-010-0140-y.
    • (2010) Target Oncol , vol.5 , Issue.4 , pp. 245-255
    • Spicer, J.F.1    Rudman, S.M.2
  • 23
    • 84858002759 scopus 로고    scopus 로고
    • Clinical activity of afatinib (BIBW 2992) in patients with lung adenocarcinoma with mutations in the kinase domain of HER2/neu
    • PID: 22325357
    • De Greve J, Teugels E, Geers C, Decoster L, Galdermans D, De Mey J, et al. Clinical activity of afatinib (BIBW 2992) in patients with lung adenocarcinoma with mutations in the kinase domain of HER2/neu. Lung Cancer. 2012;76(1):123–7. doi:10.1016/j.lungcan.2012.01.008.
    • (2012) Lung Cancer , vol.76 , Issue.1 , pp. 123-127
    • De Greve, J.1    Teugels, E.2    Geers, C.3    Decoster, L.4    Galdermans, D.5    De Mey, J.6
  • 24
    • 84921892043 scopus 로고    scopus 로고
    • Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials
    • COI: 1:CAS:528:DC%2BC2MXhtVGmu78%3D, PID: 25589191
    • Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, et al. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials. Lancet Oncol. 2015;16(2):141–51. doi:10.1016/S1470-2045(14)71173-8.
    • (2015) Lancet Oncol , vol.16 , Issue.2 , pp. 141-151
    • Yang, J.C.1    Wu, Y.L.2    Schuler, M.3    Sebastian, M.4    Popat, S.5    Yamamoto, N.6
  • 25
    • 84862785051 scopus 로고    scopus 로고
    • Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial
    • COI: 1:CAS:528:DC%2BC38Xmslyhsbg%3D, PID: 22452896
    • Miller VA, Hirsh V, Cadranel J, Chen YM, Park K, Kim SW, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol. 2012;13(5):528–38. doi:10.1016/S1470-2045(12)70087-6.
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 528-538
    • Miller, V.A.1    Hirsh, V.2    Cadranel, J.3    Chen, Y.M.4    Park, K.5    Kim, S.W.6
  • 26
    • 84872801006 scopus 로고    scopus 로고
    • Clinical significance of serum hepatocyte growth factor and epidermal growth factor gene somatic mutations in patients with non-squamous non-small cell lung cancer receiving gefitinib or erlotinib
    • COI: 1:CAS:528:DC%2BC38Xht1GrsrjL, PID: 21779929
    • Masago K, Togashi Y, Fujita S, Sakamori Y, Okuda C, Kim YH, et al. Clinical significance of serum hepatocyte growth factor and epidermal growth factor gene somatic mutations in patients with non-squamous non-small cell lung cancer receiving gefitinib or erlotinib. Med Oncol. 2012;29(3):1614–21. doi:10.1007/s12032-011-0009-7.
    • (2012) Med Oncol , vol.29 , Issue.3 , pp. 1614-1621
    • Masago, K.1    Togashi, Y.2    Fujita, S.3    Sakamori, Y.4    Okuda, C.5    Kim, Y.H.6
  • 27
    • 80053627035 scopus 로고    scopus 로고
    • Association between plasma hepatocyte growth factor and gefitinib resistance in patients with advanced non-small cell lung cancer
    • PID: 21440951
    • Han JY, Kim JY, Lee SH, Yoo NJ, Choi BG. Association between plasma hepatocyte growth factor and gefitinib resistance in patients with advanced non-small cell lung cancer. Lung Cancer. 2011;74(2):293–9. doi:10.1016/j.lungcan.2011.02.021.
    • (2011) Lung Cancer , vol.74 , Issue.2 , pp. 293-299
    • Han, J.Y.1    Kim, J.Y.2    Lee, S.H.3    Yoo, N.J.4    Choi, B.G.5
  • 28
    • 84884736973 scopus 로고    scopus 로고
    • Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
    • COI: 1:CAS:528:DC%2BC3sXhs1KrsrzP
    • Sequist LV, Yang JC, Yamamoto N, O’Byrne K, Hirsh V, Mok T, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(27):3327–34. doi:10.1200/JCO.2012.44.2806.
    • (2013) J Clin Oncol Off J Am Soc Clin Oncol , vol.31 , Issue.27 , pp. 3327-3334
    • Sequist, L.V.1    Yang, J.C.2    Yamamoto, N.3    O’Byrne, K.4    Hirsh, V.5    Mok, T.6
  • 29
    • 84892997539 scopus 로고    scopus 로고
    • Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial
    • COI: 1:CAS:528:DC%2BC2cXhtF2gu78%3D, PID: 24439929
    • Wu YL, Zhou C, Hu CP, Feng J, Lu S, Huang Y, et al. Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial. Lancet Oncol. 2014;15(2):213–22. doi:10.1016/S1470-2045(13)70604-1.
    • (2014) Lancet Oncol , vol.15 , Issue.2 , pp. 213-222
    • Wu, Y.L.1    Zhou, C.2    Hu, C.P.3    Feng, J.4    Lu, S.5    Huang, Y.6
  • 30
    • 84866594844 scopus 로고    scopus 로고
    • Targeting the hepatocyte growth factor-cMET axis in cancer therapy
    • COI: 1:CAS:528:DC%2BC38XhsVKrsL%2FE
    • Blumenschein Jr GR, Mills GB, Gonzalez-Angulo AM. Targeting the hepatocyte growth factor-cMET axis in cancer therapy. J Clin Oncol Off J Am Soc Clin Oncol. 2012;30(26):3287–96. doi:10.1200/JCO.2011.40.3774.
    • (2012) J Clin Oncol Off J Am Soc Clin Oncol , vol.30 , Issue.26 , pp. 3287-3296
    • Blumenschein, G.R.1    Mills, G.B.2    Gonzalez-Angulo, A.M.3
  • 31
    • 0030844390 scopus 로고    scopus 로고
    • Serum hepatocyte growth factor/scatter factor levels in small cell lung cancer patients
    • COI: 1:STN:280:DyaK2szotVeltA%3D%3D, PID: 9237156
    • Takigawa N, Segawa Y, Maeda Y, Takata I, Fujimoto N. Serum hepatocyte growth factor/scatter factor levels in small cell lung cancer patients. Lung Cancer. 1997;17(2-3):211–8.
    • (1997) Lung Cancer , vol.17 , Issue.2-3 , pp. 211-218
    • Takigawa, N.1    Segawa, Y.2    Maeda, Y.3    Takata, I.4    Fujimoto, N.5
  • 32
    • 68549118762 scopus 로고    scopus 로고
    • Serum hepatocyte growth factor as a prognostic marker for stage II or III colorectal cancer patients
    • COI: 1:CAS:528:DC%2BD1MXpsVKmtrY%3D
    • Toiyama Y, Miki C, Inoue Y, Okugawa Y, Tanaka K, Kusunoki M. Serum hepatocyte growth factor as a prognostic marker for stage II or III colorectal cancer patients. Int J Cancer J Int cancer. 2009;125(7):1657–62. doi:10.1002/ijc.24554.
    • (2009) Int J Cancer J Int cancer , vol.125 , Issue.7 , pp. 1657-1662
    • Toiyama, Y.1    Miki, C.2    Inoue, Y.3    Okugawa, Y.4    Tanaka, K.5    Kusunoki, M.6
  • 33
    • 4143118791 scopus 로고    scopus 로고
    • Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma
    • COI: 1:CAS:528:DC%2BD2cXnslantb4%3D, PID: 15513361
    • Tanaka K, Miki C, Wakuda R, Kobayashi M, Tonouchi H, Kusunoki M. Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma. Scand J Gastroenterol. 2004;39(8):754–60. doi:10.1080/00365520410005973.
    • (2004) Scand J Gastroenterol , vol.39 , Issue.8 , pp. 754-760
    • Tanaka, K.1    Miki, C.2    Wakuda, R.3    Kobayashi, M.4    Tonouchi, H.5    Kusunoki, M.6
  • 34
    • 58149347700 scopus 로고    scopus 로고
    • Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    • COI: 1:CAS:528:DC%2BD1cXhtlylur%2FJ
    • Gupta A, Karakiewicz PI, Roehrborn CG, Lotan Y, Zlotta AR, Shariat SF. Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer. Clin Cancer Res Off J Am Assoc Cancer Res. 2008;14(22):7385–90. doi:10.1158/1078-0432.CCR-07-5110.
    • (2008) Clin Cancer Res Off J Am Assoc Cancer Res , vol.14 , Issue.22 , pp. 7385-7390
    • Gupta, A.1    Karakiewicz, P.I.2    Roehrborn, C.G.3    Lotan, Y.4    Zlotta, A.R.5    Shariat, S.F.6
  • 35
    • 0032006829 scopus 로고    scopus 로고
    • Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma
    • COI: 1:STN:280:DyaK1c7hvVWqtg%3D%3D
    • Seidel C, Borset M, Turesson I, Abildgaard N, Sundan A, Waage A. Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma. Nord Myeloma Study Group Blood. 1998;91(3):806–12.
    • (1998) Nord Myeloma Study Group Blood , vol.91 , Issue.3 , pp. 806-812
    • Seidel, C.1    Borset, M.2    Turesson, I.3    Abildgaard, N.4    Sundan, A.5    Waage, A.6
  • 36
    • 77953287543 scopus 로고    scopus 로고
    • Hepatocyte growth factor in cerebrospinal fluid is associated with mortality and recurrence of glioblastoma, and could be of prognostic value
    • COI: 1:CAS:528:DC%2BC3cXltFOnsLk%3D
    • Garcia-Navarrete R, Garcia E, Arrieta O, Sotelo J. Hepatocyte growth factor in cerebrospinal fluid is associated with mortality and recurrence of glioblastoma, and could be of prognostic value. J Neuro-Oncol. 2010;97(3):347–51. doi:10.1007/s11060-009-0037-8.
    • (2010) J Neuro-Oncol , vol.97 , Issue.3 , pp. 347-351
    • Garcia-Navarrete, R.1    Garcia, E.2    Arrieta, O.3    Sotelo, J.4
  • 37
    • 0037096867 scopus 로고    scopus 로고
    • Hepatocyte growth factor is associated with poor prognosis of malignant gliomas and is a predictor for recurrence of meningioma
    • COI: 1:CAS:528:DC%2BD38XltlOqu7w%3D, PID: 12115353
    • Arrieta O, Garcia E, Guevara P, Garcia-Navarrete R, Ondarza R, Rembao D, et al. Hepatocyte growth factor is associated with poor prognosis of malignant gliomas and is a predictor for recurrence of meningioma. Cancer. 2002;94(12):3210–8. doi:10.1002/cncr.10594.
    • (2002) Cancer , vol.94 , Issue.12 , pp. 3210-3218
    • Arrieta, O.1    Garcia, E.2    Guevara, P.3    Garcia-Navarrete, R.4    Ondarza, R.5    Rembao, D.6
  • 38
    • 4344594389 scopus 로고    scopus 로고
    • Coexpression of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor cMET predict recurrence of meningiomas
    • COI: 1:CAS:528:DC%2BD2cXmslelsbk%3D, PID: 15312691
    • Martinez-Rumayor A, Arrieta O, Guevara P, Escobar E, Rembao D, Salina C, et al. Coexpression of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor cMET predict recurrence of meningiomas. Cancer Lett. 2004;213(1):117–24. doi:10.1016/j.canlet.2004.04.026.
    • (2004) Cancer Lett , vol.213 , Issue.1 , pp. 117-124
    • Martinez-Rumayor, A.1    Arrieta, O.2    Guevara, P.3    Escobar, E.4    Rembao, D.5    Salina, C.6
  • 39
    • 84920572810 scopus 로고    scopus 로고
    • The role of cMet in non-small cell lung cancer resistant to EGFR-inhibitors: did we really find the target?
    • COI: 1:CAS:528:DC%2BC2MXotVOjtg%3D%3D, PID: 25511614
    • Passiglia F, Van Der Steen N, Raez L, Pauwels P, Gil-Bazo I, Santos E, et al. The role of cMet in non-small cell lung cancer resistant to EGFR-inhibitors: did we really find the target? Curr Drug Targets. 2014;15(14):1284–92.
    • (2014) Curr Drug Targets , vol.15 , Issue.14 , pp. 1284-1292
    • Passiglia, F.1    Van Der Steen, N.2    Raez, L.3    Pauwels, P.4    Gil-Bazo, I.5    Santos, E.6
  • 40
    • 84890108571 scopus 로고    scopus 로고
    • Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BC3sXhvFSksrfN
    • Spigel DR, Ervin TJ, Ramlau RA, Daniel DB, Goldschmidt Jr JH, Blumenschein Jr GR, et al. Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(32):4105–14. doi:10.1200/JCO.2012.47.4189.
    • (2013) J Clin Oncol Off J Am Soc Clin Oncol , vol.31 , Issue.32 , pp. 4105-4114
    • Spigel, D.R.1    Ervin, T.J.2    Ramlau, R.A.3    Daniel, D.B.4    Goldschmidt, J.H.5    Blumenschein, G.R.6
  • 41
    • 84904679830 scopus 로고    scopus 로고
    • Onartuzumab plus erlotinib versus erlotinib in previously treated stage IIIb and IV NSCLC: results from the pivotal phase III randomized, multicenter, placebo-controlled METLung (OAM4971g) global trial
    • Spigel DR, Edelman MJ, O’Byrne K, Paz-Ares L, Shames DS, Yu W, et al. Onartuzumab plus erlotinib versus erlotinib in previously treated stage IIIb and IV NSCLC: results from the pivotal phase III randomized, multicenter, placebo-controlled METLung (OAM4971g) global trial. J Clin Oncol. 2014;32:5s (suppl; abstr 8000).
    • (2014) J Clin Oncol , vol.5s , pp. 32
    • Spigel, D.R.1    Edelman, M.J.2    O’Byrne, K.3    Paz-Ares, L.4    Shames, D.S.5    Yu, W.6
  • 42
    • 84959898696 scopus 로고    scopus 로고
    • Negative results of METLung study: an opportunity to better understand the role of MET pathway in advanced NSCLC
    • COI: 1:CAS:528:DC%2BC2MXhtFCmt7bP, PID: 25806330
    • Perol M. Negative results of METLung study: an opportunity to better understand the role of MET pathway in advanced NSCLC. Transl Lung Cancer Res. 2014;3(6):392–4. doi:10.3978/j.issn.2218-6751.2014.09.06.
    • (2014) Transl Lung Cancer Res , vol.3 , Issue.6 , pp. 392-394
    • Perol, M.1
  • 44
    • 84990312545 scopus 로고    scopus 로고
    • Randomized phase II study of ficlatuzumab (formerly AV-299), an anti-hepatocyte growth factor (HGF) monoclonal antibody (MAb) in combination with gefitinib (G) in Asian patients (pts) with NSCLC
    • Mok TET, Park K, Jac J, Han M, PayumoFC, Credi M, et al, 29(suppl; abstr TPS213)
    • Mok TET, Park K, Jac J, Han M, PayumoFC, Credi M, et al. Randomized phase II study of ficlatuzumab (formerly AV-299), an anti-hepatocyte growth factor (HGF) monoclonal antibody (MAb) in combination with gefitinib (G) in Asian patients (pts) with NSCLC. J Clin Oncol Off J Am Soc Clin Oncol. 2011;29(suppl; abstr TPS213).
    • (2011) J Clin Oncol Off J Am Soc Clin Oncol
  • 45
    • 77958074157 scopus 로고    scopus 로고
    • TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation
    • COI: 1:CAS:528:DC%2BC3cXht1KhtrjJ, PID: 20716641
    • Okamoto W, Okamoto I, Tanaka K, Hatashita E, Yamada Y, Kuwata K, et al. TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation. Mol Cancer Ther. 2010;9(10):2785–92. doi:10.1158/1535-7163.MCT-10-0481.
    • (2010) Mol Cancer Ther , vol.9 , Issue.10 , pp. 2785-2792
    • Okamoto, W.1    Okamoto, I.2    Tanaka, K.3    Hatashita, E.4    Yamada, Y.5    Kuwata, K.6
  • 46
    • 70350721786 scopus 로고    scopus 로고
    • Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors
    • COI: 1:CAS:528:DC%2BD1MXhtlCjsrbL
    • Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, et al. Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors. Clin Cancer Res Off J Am Assoc Cancer Res. 2009;15(21):6630–8. doi:10.1158/1078-0432.CCR-09-1001.
    • (2009) Clin Cancer Res Off J Am Assoc Cancer Res , vol.15 , Issue.21 , pp. 6630-6638
    • Wang, W.1    Li, Q.2    Yamada, T.3    Matsumoto, K.4    Matsumoto, I.5    Oda, M.6
  • 47
    • 84928739294 scopus 로고    scopus 로고
    • AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer
    • PID: 25923549
    • Janne PA, Yang JC, Kim DW, Planchard D, Ohe Y, Ramalingam SS, et al. AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer. N Engl J Med. 2015;372(18):1689–99. doi:10.1056/NEJMoa1411817.
    • (2015) N Engl J Med , vol.372 , Issue.18 , pp. 1689-1699
    • Janne, P.A.1    Yang, J.C.2    Kim, D.W.3    Planchard, D.4    Ohe, Y.5    Ramalingam, S.S.6
  • 49
    • 84946710397 scopus 로고    scopus 로고
    • Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors
    • COI: 1:STN:280:DC%2BC2Mjms1Orsg%3D%3D
    • Kris MG, Camidge DR, Giaccone G, Hida T, Li BT, O’Connell J, et al. Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors. Ann Oncol Off J Eur Soc Med Oncol ESMO. 2015;26(7):1421–7. doi:10.1093/annonc/mdv186.
    • (2015) Ann Oncol Off J Eur Soc Med Oncol ESMO , vol.26 , Issue.7 , pp. 1421-1427
    • Kris, M.G.1    Camidge, D.R.2    Giaccone, G.3    Hida, T.4    Li, B.T.5    O’Connell, J.6
  • 50
    • 84990311044 scopus 로고    scopus 로고
    • ClinicalTrials.gov.. Accessed 1 Dec 2015
    • Platform ETO. Afatinib in NSCLC With HER2 Mutation (NICHE). ClinicalTrials.gov. 2015-. https://clinicaltrials.gov/ct2/show/NCT02369484. Accessed 1 Dec 2015.
    • (2015) Afatinib in NSCLC With HER2 Mutation (NICHE)
  • 52
    • 84938287765 scopus 로고    scopus 로고
    • Updated Frequency of EGFR and KRAS Mutations in nonsmall-cell lung cancer in Latin America: The Latin-American consortium for the investigation of lung cancer (CLICaP)
    • COI: 1:CAS:528:DC%2BC2MXntFGmtr4%3D
    • Arrieta O, Cardona AF, Martin C, Mas-Lopez L, Corrales-Rodriguez L, Bramuglia G, et al. Updated Frequency of EGFR and KRAS Mutations in nonsmall-cell lung cancer in Latin America: The Latin-American consortium for the investigation of lung cancer (CLICaP). J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2015;10(5):838–43. doi:10.1097/JTO.0000000000000481.
    • (2015) J Thorac Oncol Off Publ Int Assoc Study Lung Cancer , vol.10 , Issue.5 , pp. 838-843
    • Arrieta, O.1    Cardona, A.F.2    Martin, C.3    Mas-Lopez, L.4    Corrales-Rodriguez, L.5    Bramuglia, G.6
  • 53
    • 84955304728 scopus 로고    scopus 로고
    • Different mutation profiles and clinical characteristics among Hispanic patients with non-small cell lung cancer could explain the “Hispanic paradox
    • PID: 26358312
    • Arrieta O, Ramirez-Tirado LA, Baez-Saldana R, Pena-Curiel O, Soca-Chafre G, Macedo-Perez EO. Different mutation profiles and clinical characteristics among Hispanic patients with non-small cell lung cancer could explain the “Hispanic paradox”. Lung Cancer. 2015;90(2):161–6. doi:10.1016/j.lungcan.2015.08.010.
    • (2015) Lung Cancer , vol.90 , Issue.2 , pp. 161-166
    • Arrieta, O.1    Ramirez-Tirado, L.A.2    Baez-Saldana, R.3    Pena-Curiel, O.4    Soca-Chafre, G.5    Macedo-Perez, E.O.6
  • 54
    • 68349088963 scopus 로고    scopus 로고
    • Wood-smoke exposure as a response and survival predictor in erlotinib-treated nonsmall cell lung cancer patients
    • Arrieta O, Rios Trejo MA, Michel RM. Wood-smoke exposure as a response and survival predictor in erlotinib-treated nonsmall cell lung cancer patients. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer. 2009;4(8):1043. doi:10.1097/JTO.0b013e3181ae2497.
    • (2009) J Thorac Oncol Off Publ Int Assoc Study Lung Cancer , vol.4 , Issue.8 , pp. 1043
    • Arrieta, O.1    Rios Trejo, M.A.2    Michel, R.M.3


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