Scrambler Therapy for the management of chronic pain

Supportive Care in Cancer

Volumn 24, Issue 6, 2016, Pages 2807-2814

  Majithia, Neil ^a   Smith, Thomas J ^b   Coyne, Patrick J ^c   Abdi, Salahadin ^d   Pachman, Deirdre R ^a   Lachance, Daniel ^a   Shelerud, Randy ^a   Cheville, Andrea ^a   Basford, Jeffrey R ^a   Farley, David ^e   O’Neill, Carrie ^a   Ruddy, Kathryn J ^a   Sparadeo, Frank ^f   Beutler, Andreas ^a   Loprinzi, Charles L ^a  

^a MAYO CLINIC   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e West Lynn Family Health Center   (United States)

^f SALVE REGINA UNIVERSITY   (United States)

Author keywords

Chemotherapy induced peripheral neuropathy; Chronic pain; Pain; Scrambler Therapy

Indexed keywords

ANALGESIA; CHRONIC PAIN; CLINICAL PRACTICE; ELECTROSTIMULATION; HUMAN; META ANALYSIS; PERIPHERAL NEUROPATHY; PHYSICAL MEDICINE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RETROSPECTIVE STUDY; REVIEW; SCRAMBLER THERAPY; SYSTEMATIC REVIEW; DEVICES; ELECTROTHERAPY; PROCEDURES;

CHRONIC PAIN; ELECTRIC STIMULATION THERAPY; HUMANS;

EID: 84962167822     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-016-3177-3     Document Type: Review

References (34)

1. Simon L (2012) Relieving pain in America: A blueprint for transforming prevention, care, education, and research. J Pain Pall Care Phmaracotherapy 26:197–198
2. Stewart WF, Ricci JA, Chee E, Morganstein D, Lipton R (2003) Lost productive time and cost due to common pain conditions in the US workforce. JAMA 290:2443–2454. doi:10.1001/jama.290.18.2443
3. Merskey H, Bogduk N (1994) Classification of chronic pain, 2nd edn. IASP Press, Seattle
4. Merskey H, Harold E (1986) Classification of chronic pain: descriptions of chronic pain syndromes and definitions of pain terms. Pain 3:S1–226
5. Woolf CJ, Doubell TP (1994) The pathophysiology of chronic pain—increased sensitivity to low threshold A beta-fibre inputs. Curr Opin Neurobiol 4:525–534
6. Zimmermann M (2001) Pathobiology of neuropathic pain. Eur J Pharmacol 429:23–37
7. Ji RR, Kohno T, Moore KA, Woolf CJ (2003) Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neurosci 26:696–705. doi:10.1016/j.tins.2003.09.017
8. Freynhagen R, Bennett MI (2009) Diagnosis and management of neuropathic pain. BMJ 339:b3002. doi:10.1136/bmj.b3002
9. Allegrante JP (1996) The role of adjunctive therapy in the management of chronic nonmalignant pain. Am J Med 101:33S–39S
10. Maurer D (1974) Transcutaneous stimulator and stimulation method. Google Patents.
11. Cruccu G, Aziz TZ, Garcia-Larrea L, Hansson P, Jensen TS, Lefaucheur JP, Simpson BA, Taylor RS (2007) EFNS guidelines on neurostimulation therapy for neuropathic pain. Eur J Neurol 14:952–970. doi:10.1111/j.1468-1331.2007.01916.x
12. Nnoaham KE, Kumbang J (2008) Transcutaneous electrical nerve stimulation (TENS) for chronic pain. Cochrane Database Syst Rev:CD003222. doi:10.1002/14651858.CD003222.pub2
13. Marineo G (2003) Untreatable pain resulting from abdominal cancer: new hope from biophysics? JOP 4:1–10
14. Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Leong M, Levy RM, Abejon D, Buchser E, Burton A, Buvanendran A, Candido K, Caraway D, Cousins M, DeJongste M, Diwan S, Eldabe S, Gatzinsky K, Foreman RD, Hayek S, Kim P, Kinfe T, Kloth D, Kumar K, Rizvi S, Lad SP, Liem L, Linderoth B, Mackey S, McDowell G, McRoberts P, Poree L, Prager J, Raso L, Rauck R, Russo M, Simpson B, Slavin K, Staats P, Stanton-Hicks M, Verrills P, Wellington J, Williams K, North R (2014) The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee. Neuromodulation 17:515–550. doi:10.1111/ner.12208
15. Abdi S, Lakkimsetty VM, Barrera J, Candiotti K, Lubarsky D (2011) The Use of “Scrambler Therapy” for Failed Back Surgery Syndrome. Pain Physician 14:E465–E491
16. Campbell T, Nimunkar AJ, Retseck J, Eickhoff JC, Backonja M, Cleary JF, Kwekkeboom KL, Yen TY (2013) A randomized, double-blind study of “Scrambler” therapy versus sham for painful chemotherapy-induced peripheral neuropathy (CIPN). J Clin Oncol 31:suppl; abstr 9635.
17. Coyne PJ, Wan W, Dodson P, Swainey C, Smith TJ (2013) A Trial of Scrambler Therapy in the Treatment of Cancer Pain Syndromes and Chronic Chemotherapy-Induced Peripheral Neuropathy. J Pain Palliat Care Pharmacother 27:359–364. doi:10.3109/15360288.2013.847519
18. Ghatak RK, Nandi SN, Bhakta A, Mandal GC, Bandyopadhyay M, Kumar S (2011) Prospective study of application of biological communication (cybernatics) in management of chronic low back pain—a preliminary report. Nepal Med Coll J 13:257–260
19. Ko YK, Lee HY, Lee WY (2013) Clinical experiences on the effect of scrambler therapy for patients with postherpetic neuralgia. Korean J Pain 26:98–101. doi:10.3344/kjp.2013.26.1.98
20. Marineo G, Iorno V, Gandini C, Moschini V, Smith TJ (2011) Scrambler Therapy May Relieve Chronic Neuropathic Pain More Effectively Than Guideline-Based Drug Management: Results of a Pilot, Randomized, Controlled Trial. J Pain Symptom Manage 43:87–95. doi:10.1016/j.jpainsymman.2011.03.015
21. Moon JY, Kurihara C, Beckles JP, Williams KE, Jamison DE, Cohen SP (2014) Predictive factors associated with success and failure for calmare (Scrambler) therapy: a multi-center analysis. Clin J Pain 31:750–756. doi:10.1097/AJP.0000000000000155
22. Pachman DR, Weisbrod BL, Seisler DK, Barton DL, Fee-Schroeder KC, Smith TJ, Lachance DH, Liu H, Shelerud RA, Cheville AL, Loprinzi CL (2014) Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy. Support Care Cancer 23:943–951. doi:10.1007/s00520-014-2424-8
23. Park HS, Sin WK, Kim HY, Moon JY, Park SY, Kim YC, Lee SC (2013) Scrambler therapy for patients with cancer pain - case series. Korean J Pain 26:65–71. doi:10.3344/kjp.2013.26.1.65
24. Sabato AF, Marineo G, Gatti A (2005) Scrambler therapy. Minerva Anestesiol 71:479–482
25. Smith TJ, Marineo G (2013) Treatment of postherpetic pain with scrambler therapy, a patient-specific neurocutaneous electrical stimulation device. Am J Hosp Palliat Care. doi:10.1177/1049909113494002
26. Sparadeo F, Kaufman C, D’Amato S (2014) Scrambler Therapy: Effective use of artificial neurons for the treatment of neuropathic pain. J Life Care Plan 14(4):19–30
27. Sparadeo FCK, D’Amato S (2012) Scrambler Therapy: An Innovative and Effective Treatment for Chronic Neuropathic Pain. J Life Care Plan 11(3):3–15
28. Ricci M, Pirotti S, Scarpi E, Burgio M, Maltoni M, Sansoni E, Amadori D (2011) Managing chronic pain: results from an open-label study using MC5-A Calmare(R) device. Support Care Cancer 20:405–412. doi:10.1007/s00520-011-1128-6
29. Starkweather AR, Coyne P, Lyon DE, Elswick RK Jr, An K, Sturgill J (2015) Decreased low back pain intensity and differential gene expression following calmare(R): results from a double-blinded randomized sham-controlled study. Res Nurs Health 38:29–38. doi:10.1002/nur.21632
30. Smith TJ, Coyne PJ, Parker GL, Dodson P, Ramakrishnan V (2010) Pilot trial of a patient-specific cutaneous electrostimulation device (MC5-A Calmare(R)) for chemotherapy-induced peripheral neuropathy. J Pain Symptom Manage 40:883–891. doi:10.1016/j.jpainsymman.2010.03.022
31. Notaro P, Dell’Agnola CA, Dell’Agnola AJ, Amatu A, Bencardino KB, Siena S (2015) Pilot evaluation of scrambler therapy for pain induced by bone and visceral metastases and refractory to standard therapies. Support Care Cancer. doi:10.1007/s00520-015-2952-x
32. Lee SC, Park KS, Moon JY, Kim EJ, Kim YC, Seo H, Kyung J, Lee DJ (2016) An exploratory study on the effectiveness of “Calmare therapy” in patients with cancer-related neuropathic pain: A pilot study. Eur J Oncol Nurs 21:1–7
33. Compagnone C, Tagliaferri F (2015) Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis. Acta Biomed 86:149–156
34. Gustin SM, Peck CC, Wilcox SL, Nash PG, Murray GM, Henderson LA (2011) Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes. J Neurosci 31:5956–5964. doi:10.1523/JNEUROSCI.5980-10.2011