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Volumn 2015, Issue 10, 2015, Pages

Growth factors for treating diabetic foot ulcers

Author keywords

[No Author keywords available]

Indexed keywords

BECAPLERMIN; DERMAGEN; GROWTH FACTOR; LACTOFERRIN; PEPTIDE DERIVATIVE; PLACEBO; PLATELET DERIVED GROWTH FACTOR; RECOMBINANT ACIDIC FIBROBLAST GROWTH FACTOR; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; RECOMBINANT EPIDERMAL GROWTH FACTOR; RECOMBINANT LACTOFERRIN; RECOMBINANT PROTEIN; RECOMBINANT VASCULOTROPIN; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; GROWTH PROMOTOR;

EID: 84962130435     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD008548.pub2     Document Type: Review
Times cited : (155)

References (183)
  • 3
    • 57949103536 scopus 로고    scopus 로고
    • Which is the better option: recombinant human PDGF-BB 0.01% gel or standard wound care, in diabetic neuropathic large plantar ulcers off-loaded by a customized contact cast?
    • Bhansali A, Venkatesh S, Dutta P, Dhillon MS, Das S, Agrawal A. Which is the better option: recombinant human PDGF-BB 0.01% gel or standard wound care, in diabetic neuropathic large plantar ulcers off-loaded by a customized contact cast?. Diabetes Research and Clinical Practice 2009;83(1):e13-6.
    • (2009) Diabetes Research and Clinical Practice , vol.83 , Issue.1 , pp. e13-e16
    • Bhansali, A.1    Venkatesh, S.2    Dutta, P.3    Dhillon, M.S.4    Das, S.5    Agrawal, A.6
  • 4
    • 85041724432 scopus 로고    scopus 로고
    • Analysis of the effect of recombined human epidermal growth factor derivate applied externally in treating diabetic foot
    • Chen A, Long XH, Huang C. Analysis of the effect of recombined human epidermal growth factor derivate applied externally in treating diabetic foot. Modern Nursing 2004;10(3):274-5.
    • (2004) Modern Nursing , vol.10 , Issue.3 , pp. 274-275
    • Chen, A.1    Long, X.H.2    Huang, C.3
  • 5
    • 85041723300 scopus 로고    scopus 로고
    • The effect of topically applied sodium carboxymethylcellulose gel in nonhealing, lower extremity ulcers in patients with diabetes
    • Koln, Germany, 23-27 August
    • d'Hemecourt PA, Smeill JM, Hugill JV, Prigoff MM. The effect of topically applied sodium carboxymethylcellulose gel in nonhealing, lower extremity ulcers in patients with diabetes. European Tissue Repair Society. Koln, Germany, 23-27 August 1997:Abstracts.
    • (1997) European Tissue Repair Society
    • d'Hemecourt, P.A.1    Smeill, J.M.2    Hugill, J.V.3    Prigoff, M.M.4
  • 6
    • 0032399279 scopus 로고    scopus 로고
    • Sodium carboxymethyl cellulose aqueous-based gel vs becaplermin gel in patients with nonhealing lower extremity diabetic ulcers
    • d'Hemecourt PA, Smiell JM, Karim MR. Sodium carboxymethyl cellulose aqueous-based gel vs becaplermin gel in patients with nonhealing lower extremity diabetic ulcers. Wounds 1998;10(3):69-75.
    • (1998) Wounds , vol.10 , Issue.3 , pp. 69-75
    • d'Hemecourt, P.A.1    Smiell, J.M.2    Karim, M.R.3
  • 7
    • 84874301990 scopus 로고    scopus 로고
    • A prospective, randomized, controlled, blinded, multicenter pivotal trial of a platelet rich plasma gel versus control when added to the standard of care in the treatment of non-healing diabetic foot ulcers
    • Driver VR. A prospective, randomized, controlled, blinded, multicenter pivotal trial of a platelet rich plasma gel versus control when added to the standard of care in the treatment of non-healing diabetic foot ulcers. Diabetes 2006;55(Suppl 1):A25.
    • (2006) Diabetes , vol.55 , pp. A25
    • Driver, V.R.1
  • 8
    • 33747621370 scopus 로고    scopus 로고
    • A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers
    • Driver VR, Hanft J, Fylling CP, Beriou JM, AutoGel Diabetic Foot Ulcer Study Group. A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Ostomy/Wound Management 2006;52(6):68-87.
    • (2006) Ostomy/Wound Management , vol.52 , Issue.6 , pp. 68-87
    • Driver, V.R.1    Hanft, J.2    Fylling, C.P.3    Beriou, J.M.4
  • 11
    • 73649083748 scopus 로고    scopus 로고
    • Intra-lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo-controlled, double-blind study
    • Fernández-Montequín JI, Valenzuela-Silva CM, Díaz OG, Savigne W, Sancho-Soutelo N, Rivero-Fernández F, Cuban Diabetic Foot Study Group. Intra-lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo-controlled, double-blind study. International Wound Journal 2009;6:432-43.
    • (2009) International Wound Journal , vol.6 , pp. 432-443
    • Fernández-Montequín, J.I.1    Valenzuela-Silva, C.M.2    Díaz, O.G.3    Savigne, W.4    Sancho-Soutelo, N.5    Rivero-Fernández, F.6
  • 13
    • 85041712873 scopus 로고    scopus 로고
    • Results of a phase I, randomized, double-blind, placebo-controlled trial of topical rhVEGF (telbermin) for the treatment of diabetic foot ulcers
    • Kwon P, Breen TJ, Gray S, Lynch CJ, Semba CP, Hanft JR, et al. Results of a phase I, randomized, double-blind, placebo-controlled trial of topical rhVEGF (telbermin) for the treatment of diabetic foot ulcers. Wound Management 2006;54:102.
    • (2006) Wound Management , vol.54 , pp. 102
    • Kwon, P.1    Breen, T.J.2    Gray, S.3    Lynch, C.J.4    Semba, C.P.5    Hanft, J.R.6
  • 14
    • 22244469421 scopus 로고    scopus 로고
    • Efficacy of recombinant human platelet-derived growth factor (rhPDGF) based gel in diabetic foot ulcers: a randomized, multicenter, double-blind, placebo-controlled study in India
    • Hardikar JV, Reddy YC, Bung DD, Varma N, Shilotri PP, Prasad ED, et al. Efficacy of recombinant human platelet-derived growth factor (rhPDGF) based gel in diabetic foot ulcers: a randomized, multicenter, double-blind, placebo-controlled study in India. Wounds 2005;17:141-52.
    • (2005) Wounds , vol.17 , pp. 141-152
    • Hardikar, J.V.1    Reddy, Y.C.2    Bung, D.D.3    Varma, N.4    Shilotri, P.P.5    Prasad, E.D.6
  • 15
    • 21144460031 scopus 로고
    • A randomised controlled dose response trial of activated platelet supernatant, topical CT-102 in chronic, non healing diabetic wounds
    • Holloway GA, Steed DL, DeMarco MJ, Matsumoto T, Moosa HH, Webster MW, et al. A randomised controlled dose response trial of activated platelet supernatant, topical CT-102 in chronic, non healing diabetic wounds. Wounds 1993;5:198-206.
    • (1993) Wounds , vol.5 , pp. 198-206
    • Holloway, G.A.1    Steed, D.L.2    DeMarco, M.J.3    Matsumoto, T.4    Moosa, H.H.5    Webster, M.W.6
  • 16
    • 76749130538 scopus 로고    scopus 로고
    • Efficacy of topical recombinant human platelet derived growth factor on wound healing in patients with chronic diabetic lower limb ulcers
    • Jaiswal SS, Gambhir RPS, Harish AA. Efficacy of topical recombinant human platelet derived growth factor on wound healing in patients with chronic diabetic lower limb ulcers. Indian Journal of Surgery 2010;72:31-5.
    • (2010) Indian Journal of Surgery , vol.72 , pp. 31-35
    • Jaiswal, S.S.1    Gambhir, R.P.S.2    Harish, A.A.3
  • 18
    • 77957741021 scopus 로고    scopus 로고
    • Diabetic foot ulcers treated with becaplermin and TheraGauze, a moisture-controlling smart dressing: a randomized, multicenter, prospective analysis
    • Landsman A, Agnew P, Parish L, Joseph R, Galiano RD. Diabetic foot ulcers treated with becaplermin and TheraGauze, a moisture-controlling smart dressing: a randomized, multicenter, prospective analysis. Journal of the American Podiatric Medical Association 2010;100(3):155-60.
    • (2010) Journal of the American Podiatric Medical Association , vol.100 , Issue.3 , pp. 155-160
    • Landsman, A.1    Agnew, P.2    Parish, L.3    Joseph, R.4    Galiano, R.D.5
  • 19
    • 85036597428 scopus 로고    scopus 로고
    • Diabetic foot ulcers: a randomized multicenter study comparing a moisture-controlling dressing with a topical growth factor
    • Parish L, Routh H, Parish J. Diabetic foot ulcers: a randomized multicenter study comparing a moisture-controlling dressing with a topical growth factor. Journal of the American Academy of Dermatology 2009;60(Suppl):AB202.
    • (2009) Journal of the American Academy of Dermatology , vol.60 , pp. 202
    • Parish, L.1    Routh, H.2    Parish, J.3
  • 20
    • 33845586995 scopus 로고    scopus 로고
    • Talactoferrin alfa, a recombinant human lactoferrin promotes healing of diabetic neuropathic ulcers: a phase 1/2 clinical study
    • Lyons TE, Miller MS, Serena T, Sheehan P, Lavery L, Kirsner RS, et al. Talactoferrin alfa, a recombinant human lactoferrin promotes healing of diabetic neuropathic ulcers: a phase 1/2 clinical study. American Journal of Surgery 2007;193(1):49-54.
    • (2007) American Journal of Surgery , vol.193 , Issue.1 , pp. 49-54
    • Lyons, T.E.1    Miller, M.S.2    Serena, T.3    Sheehan, P.4    Lavery, L.5    Kirsner, R.S.6
  • 22
    • 0028796620 scopus 로고
    • Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot: A pilot, randomized, double-blind, placebo-controlled study
    • Richard JL, Parer-Richard C, Daures JP, Clouet S, Vannereau D, Bringer J, et al. Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot: A pilot, randomized, double-blind, placebo-controlled study. Diabetes Care 1995;18:64-9.
    • (1995) Diabetes Care , vol.18 , pp. 64-69
    • Richard, J.L.1    Parer-Richard, C.2    Daures, J.P.3    Clouet, S.4    Vannereau, D.5    Bringer, J.6
  • 23
    • 52449111832 scopus 로고    scopus 로고
    • Effects of transforming growth factor +2 on wound healing in diabetic foot ulcers: a randomized controlled safety and dose-ranging trial
    • Robson MC, Steed DL, McPherson JM, Pratt BM. Effects of transforming growth factor +2 on wound healing in diabetic foot ulcers: a randomized controlled safety and dose-ranging trial. Journal of Applied Research 2002;2:133-45.
    • (2002) Journal of Applied Research , vol.2 , pp. 133-145
    • Robson, M.C.1    Steed, D.L.2    McPherson, J.M.3    Pratt, B.M.4
  • 26
    • 0026793943 scopus 로고
    • Randomised prospective double blind trial in healing chronic diabetic foot ulcers: CT-102 activated platelet supernatant, topical versus placebo
    • Steed D, Goslen JB, Holloway GA, Malone JM, Bunt TJ, Webster MW. Randomised prospective double blind trial in healing chronic diabetic foot ulcers: CT-102 activated platelet supernatant, topical versus placebo. Diabetes Care 1992;15:1598-604.
    • (1992) Diabetes Care , vol.15 , pp. 1598-1604
    • Steed, D.1    Goslen, J.B.2    Holloway, G.A.3    Malone, J.M.4    Bunt, T.J.5    Webster, M.W.6
  • 27
    • 33745513688 scopus 로고    scopus 로고
    • Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers
    • Steed DL. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers. Plastic and Reconstructive Surgery 2006;117 (Suppl7):143-9.
    • (2006) Plastic and Reconstructive Surgery , vol.117 , pp. 143-149
    • Steed, D.L.1
  • 28
    • 0028873980 scopus 로고
    • Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers
    • Steed DL, Webster MW, Ricotta JJ, Luterman A, Brown S, Comerota AJ, et al. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers. Journal of Vascular Surgery 1995;21:71-81.
    • (1995) Journal of Vascular Surgery , vol.21 , pp. 71-81
    • Steed, D.L.1    Webster, M.W.2    Ricotta, J.J.3    Luterman, A.4    Brown, S.5    Comerota, A.J.6
  • 29
    • 0028873826 scopus 로고
    • Promotion and acceleration of diabetic ulcer healing by arginine glycine-aspartic acid (RGD) peptide matrix
    • Steed D, Ricotta JJ, Prendergast JJ, Kaplan RJ, Webster MW, McGill JB, et al. Promotion and acceleration of diabetic ulcer healing by arginine glycine-aspartic acid (RGD) peptide matrix. Diabetes Care 1995;18:39-46.
    • (1995) Diabetes Care , vol.18 , pp. 39-46
    • Steed, D.1    Ricotta, J.J.2    Prendergast, J.J.3    Kaplan, R.J.4    Webster, M.W.5    McGill, J.B.6
  • 30
    • 0005696303 scopus 로고    scopus 로고
    • Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets
    • Steed DL, Edington HD, Webster MW. Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets. Wound Repair and Regeneration 1996;4:230-3.
    • (1996) Wound Repair and Regeneration , vol.4 , pp. 230-233
    • Steed, D.L.1    Edington, H.D.2    Webster, M.W.3
  • 31
    • 48749090758 scopus 로고    scopus 로고
    • Comparison of the therapeutic effects of recombinant human acidic and basic fibroblast growth factors in wound healing in diabetic patients
    • Tan Y, Xiao J, Huang Z, Xiao Y, Lin S, Jin L, et al. Comparison of the therapeutic effects of recombinant human acidic and basic fibroblast growth factors in wound healing in diabetic patients. Journal of Health Science 2008;54:432-40.
    • (2008) Journal of Health Science , vol.54 , pp. 432-440
    • Tan, Y.1    Xiao, J.2    Huang, Z.3    Xiao, Y.4    Lin, S.5    Jin, L.6
  • 34
    • 33748338753 scopus 로고    scopus 로고
    • A phase III study to evaluate the safety and efficacy of recombinant human epidermal growth factor (REGEN-D 150) in healing diabetic foot ulcers
    • Viswanathan V, Pendsey S, Sekar N, Murthy GSR. A phase III study to evaluate the safety and efficacy of recombinant human epidermal growth factor (REGEN-D 150) in healing diabetic foot ulcers. Wounds 2006;18:186-96.
    • (2006) Wounds , vol.18 , pp. 186-196
    • Viswanathan, V.1    Pendsey, S.2    Sekar, N.3    Murthy, G.S.R.4
  • 35
    • 0031734833 scopus 로고    scopus 로고
    • Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers. A phase III randomized placebo-controlled double-blind study
    • Wieman TJ, Smiell JM, Su Y. Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers. A phase III randomized placebo-controlled double-blind study. Diabetes Care 1998;21(5):822-7.
    • (1998) Diabetes Care , vol.21 , Issue.5 , pp. 822-827
    • Wieman, T.J.1    Smiell, J.M.2    Su, Y.3
  • 36
    • 33748904925 scopus 로고    scopus 로고
    • Epidermal growth factor intralesional infiltrations can prevent amputation in patients with advanced diabetic foot wounds
    • Acosta JB, Savigne W, Valdez C, Franco N, Alba JS, del Rio A, et al. Epidermal growth factor intralesional infiltrations can prevent amputation in patients with advanced diabetic foot wounds. International Wound Journal 2006;3(3):232-9.
    • (2006) International Wound Journal , vol.3 , Issue.3 , pp. 232-239
    • Acosta, J.B.1    Savigne, W.2    Valdez, C.3    Franco, N.4    Alba, J.S.5    del Rio, A.6
  • 37
    • 33845297747 scopus 로고    scopus 로고
    • Topical autologous platelet-derived growth factors in the treatment of chronic diabetes ulcers
    • Aminian B, Shams M, Soveyd M, Omrani GhR. Topical autologous platelet-derived growth factors in the treatment of chronic diabetes ulcers. Archives of Iranian Medicine 2000; Vol. 3, issue 2:55-9.
    • (2000) Archives of Iranian Medicine , vol.3 , Issue.2 , pp. 55-59
    • Aminian, B.1    Shams, M.2    Soveyd, M.3    Omrani, G.4
  • 38
    • 0033945354 scopus 로고    scopus 로고
    • Recombinant human platelet-derived growth factor-BB (becaplermin) for healing chronic lower extremity diabetic ulcers: an open-label clinical evaluation of efficacy
    • Embil JM, Papp K, Sibbald G, Tousignant J, Smiell JM, Wong B, The Canadian Becaplermin Study Group. Recombinant human platelet-derived growth factor-BB (becaplermin) for healing chronic lower extremity diabetic ulcers: an open-label clinical evaluation of efficacy. Wound Repair and Regeneration 2000;8:162-8.
    • (2000) Wound Repair and Regeneration , vol.8 , pp. 162-168
    • Embil, J.M.1    Papp, K.2    Sibbald, G.3    Tousignant, J.4    Smiell, J.M.5    Wong, B.6
  • 39
    • 33645408337 scopus 로고    scopus 로고
    • Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers
    • Hong JP, Jung HD, Kim YW. Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers. Annals of Plastic Surgery 2006;56:394-8.
    • (2006) Annals of Plastic Surgery , vol.56 , pp. 394-398
    • Hong, J.P.1    Jung, H.D.2    Kim, Y.W.3
  • 40
    • 0033026632 scopus 로고    scopus 로고
    • Use of topical recombinant human platelet-derived growth factor-BB (becaplermin) in healing of chronic mixed arteriovenous lower extremity diabetic ulcers
    • Miller MS. Use of topical recombinant human platelet-derived growth factor-BB (becaplermin) in healing of chronic mixed arteriovenous lower extremity diabetic ulcers. The Journal of Foot and Ankle Surgery 1999;38:227-31.
    • (1999) The Journal of Foot and Ankle Surgery , vol.38 , pp. 227-231
    • Miller, M.S.1
  • 41
    • 35748972337 scopus 로고    scopus 로고
    • Recombinant human epidermal growth factor (REGEN-D 150): effect on healing of diabetic foot ulcers
    • Mohan VK. Recombinant human epidermal growth factor (REGEN-D 150): effect on healing of diabetic foot ulcers. Diabetes Research and Clinical Practice 2007;78:405-11.
    • (2007) Diabetes Research and Clinical Practice , vol.78 , pp. 405-411
    • Mohan, V.K.1
  • 42
    • 79955779155 scopus 로고    scopus 로고
    • Platelet-rich plasma versus platelet-poor plasma in the management of chronic diabetic foot ulcers: a comparative study
    • Saad Setta H, Elshahat A, Elsherbiny K, Massoud K, Safe I. Platelet-rich plasma versus platelet-poor plasma in the management of chronic diabetic foot ulcers: a comparative study. International Wound Journal 2011;8(3):307-12.
    • (2011) International Wound Journal , vol.8 , Issue.3 , pp. 307-312
    • Saad Setta, H.1    Elshahat, A.2    Elsherbiny, K.3    Massoud, K.4    Safe, I.5
  • 43
    • 65349134143 scopus 로고    scopus 로고
    • The efficacy and safety of epidermal growth factor in treatment of diabetic foot ulcers: the preliminary results
    • Tuyet HL, Quynh TTN, Minh HVH, Bich DNT, Dinh TD, Tan DL, et al. The efficacy and safety of epidermal growth factor in treatment of diabetic foot ulcers: the preliminary results. International Wound Journal 2009;6:159-66.
    • (2009) International Wound Journal , vol.6 , pp. 159-166
    • Tuyet, H.L.1    Quynh, T.T.N.2    Minh, H.V.H.3    Bich, D.N.T.4    Dinh, T.D.5    Tan, D.L.6
  • 46
    • 84881182007 scopus 로고    scopus 로고
    • Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers
    • Morimoto N, Yoshimura K, Niimi M, Ito T, Aya R, Fujitaka J, et al. Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers. Tissue engineering 2013 Part A;19(17-18):1931-40.
    • (2013) Tissue engineering , vol.19 , Issue.17-18 , pp. 1931-1940
    • Morimoto, N.1    Yoshimura, K.2    Niimi, M.3    Ito, T.4    Aya, R.5    Fujitaka, J.6
  • 47
    • 84904153799 scopus 로고    scopus 로고
    • Efficacy of topical application of beta urogastrone (recombinant human epidermal growth factor) in Wagner's Grade 1 and 2 diabetic foot ulcers: Comparative analysis of 50 patients
    • Singla S, Garg R, Kumar A, Gill C. Efficacy of topical application of beta urogastrone (recombinant human epidermal growth factor) in Wagner's Grade 1 and 2 diabetic foot ulcers: Comparative analysis of 50 patients. Journal of Natural Science, Biology and Medicine 2014;5(2):273-7.
    • (2014) Journal of Natural Science, Biology and Medicine , vol.5 , Issue.2 , pp. 273-277
    • Singla, S.1    Garg, R.2    Kumar, A.3    Gill, C.4
  • 48
    • 0012533290 scopus 로고
    • The treatment of diabetic neuropathic foot ulcers with biosynthetic platelet derived growth factor
    • Young MJ, Larsen J, Knowles A, Parnell L, Ward JD. The treatment of diabetic neuropathic foot ulcers with biosynthetic platelet derived growth factor. Diabetic Medicine 1992, (Suppl 2):S42.
    • (1992) Diabetic Medicine , pp. S42
    • Young, M.J.1    Larsen, J.2    Knowles, A.3    Parnell, L.4    Ward, J.D.5
  • 49
    • 85041733092 scopus 로고    scopus 로고
    • Efficacy and Safety Study of DERMAGEN® vs Conventional Treatment to Treat Diabetic Neuropathic Foot Ulcer
    • NCT00521937. Efficacy and Safety Study of DERMAGEN® vs Conventional Treatment to Treat Diabetic Neuropathic Foot Ulcer. https://clinicaltrials.gov/ct2/show/NCT00521937.
  • 50
    • 85041705186 scopus 로고    scopus 로고
    • Clinical Evaluation of DCB-WH1 in Healing of Chronic Diabetic Foot Ulcers
    • NCT00709514. Clinical Evaluation of DCB-WH1 in Healing of Chronic Diabetic Foot Ulcers. https://clinicaltrials.gov/ct2/show/NCT00709514.
  • 51
    • 85041723942 scopus 로고    scopus 로고
    • A Dose Finding Study of Topically Applied I-020201 as an Adjunct to Good Standard-of-care in Patients With Chronic Diabetic Foot Ulcers (DFU)
    • NCT00915486. A Dose Finding Study of Topically Applied I-020201 as an Adjunct to Good Standard-of-care in Patients With Chronic Diabetic Foot Ulcers (DFU). https://clinicaltrials.gov/ct2/show/NCT00915486.
  • 52
    • 85041701240 scopus 로고    scopus 로고
    • Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers (Truheal)
    • NCT00926068. Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers (Truheal). https://clinicaltrials.gov/ct2/show/NCT00926068.
  • 53
    • 85041748394 scopus 로고    scopus 로고
    • A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers
    • NCT01060670. A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers. https://clinicaltrials.gov/ct2/show/NCT01060670.
  • 54
    • 85041697998 scopus 로고    scopus 로고
    • Comparative Study of 3 Dose Regimens of BioChaperone to Becaplermin Gel for the Treatment of Diabetic Foot Ulcer
    • NCT01098357. Comparative Study of 3 Dose Regimens of BioChaperone to Becaplermin Gel for the Treatment of Diabetic Foot Ulcer. https://clinicaltrials.gov/ct2/show/NCT01098357.
  • 55
    • 0036095250 scopus 로고    scopus 로고
    • The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort
    • Abbott CA, Carrington AL, Ashe H, Bath S, Every LC, Griffiths J, et al. North-West Diabetes Foot Care Study. The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort. Diabetes Medicine 2002;19:377-84.
    • (2002) Diabetes Medicine , vol.19 , pp. 377-384
    • Abbott, C.A.1    Carrington, A.L.2    Ashe, H.3    Bath, S.4    Every, L.C.5    Griffiths, J.6
  • 56
    • 0036814116 scopus 로고    scopus 로고
    • Cost-effective management of recalcitrant diabetic foot ulcers
    • Albert S. Cost-effective management of recalcitrant diabetic foot ulcers. Clinics in Podiatric Medicine and Surgery 2002;19:483-91.
    • (2002) Clinics in Podiatric Medicine and Surgery , vol.19 , pp. 483-491
    • Albert, S.1
  • 57
    • 53349152581 scopus 로고    scopus 로고
    • The personal cost of diabetic foot disease in the developing world -a study from Pakistan
    • Ali S, Fareed A, Humail S, Basit A, Ahmedani M, Fawwad A, et al. The personal cost of diabetic foot disease in the developing world -a study from Pakistan. Diabetic Medicine 2008; Vol. 25:1231-3.
    • (2008) Diabetic Medicine , vol.25 , pp. 1231-1233
    • Ali, S.1    Fareed, A.2    Humail, S.3    Basit, A.4    Ahmedani, M.5    Fawwad, A.6
  • 58
    • 13244258387 scopus 로고    scopus 로고
    • Growth factors and the management of the diabetic foot
    • Amery CM. Growth factors and the management of the diabetic foot. Diabetic Medicine 2005;22 Suppl 1:12-4.
    • (2005) Diabetic Medicine , vol.22 , pp. 12-14
    • Amery, C.M.1
  • 62
    • 84856148632 scopus 로고    scopus 로고
    • The development of global consensus guidelines on the management and prevention of the diabetic foot 2011
    • Bakker K, Schaper NC. The development of global consensus guidelines on the management and prevention of the diabetic foot 2011. Diabetes/Metabolism Research and Reviews 2012;28(Suppl 1):116-8.
    • (2012) Diabetes/Metabolism Research and Reviews , vol.28 , pp. 116-118
    • Bakker, K.1    Schaper, N.C.2
  • 63
  • 66
    • 12144284499 scopus 로고    scopus 로고
    • Reducing the incidence of foot ulceration and amputation in diabetes
    • Bartus CL, Margolis DJ. Reducing the incidence of foot ulceration and amputation in diabetes. Current Diabetes Reports 2004;4:413-8.
    • (2004) Current Diabetes Reports , vol.4 , pp. 413-418
    • Bartus, C.L.1    Margolis, D.J.2
  • 67
    • 84859863807 scopus 로고    scopus 로고
    • Methodological standards and patient-centeredness in comparative effectiveness research: the PCORI perspective
    • Basch E, Aronson N, Berg A, Flum D, Gabriel S, Goodman SN, et al. Methodological standards and patient-centeredness in comparative effectiveness research: the PCORI perspective. JAMA 2012;307(15):1636-40.
    • (2012) JAMA , vol.307 , Issue.15 , pp. 1636-1640
    • Basch, E.1    Aronson, N.2    Berg, A.3    Flum, D.4    Gabriel, S.5    Goodman, S.N.6
  • 68
    • 33746333563 scopus 로고    scopus 로고
    • A new wound-based severity score for diabetic foot ulcers: a prospective analysis of 1,000 patients
    • Beckert S, Witte M, Wicke C, Königsrainer A, Coerper S. A new wound-based severity score for diabetic foot ulcers: a prospective analysis of 1, 000 patients. Diabetes Care 2006;29:988-92.
    • (2006) Diabetes Care , vol.29 , pp. 988-992
    • Beckert, S.1    Witte, M.2    Wicke, C.3    Königsrainer, A.4    Coerper, S.5
  • 70
    • 65849360502 scopus 로고    scopus 로고
    • Platelha-granules: basic biology and clinical correlates
    • Blair P, Flaumenhaft R. Platelet alpha-granules: basic biology and clinical correlates. Blood Reviews 2009;23(4):177-89.
    • (2009) Blood Reviews , vol.23 , Issue.4 , pp. 177-189
    • Blair, P.1    Flaumenhaft, R.2
  • 72
    • 43049098631 scopus 로고    scopus 로고
    • The diabetic foot: grand overview, epidemiology and pathogenesis
    • Boulton AJ. The diabetic foot: grand overview, epidemiology and pathogenesis. Diabetes/Metabolism Research and Reviews 2008;24 (Suppl 1):3-6.
    • (2008) Diabetes/Metabolism Research and Reviews , vol.24 , pp. 3-6
    • Boulton, A.J.1
  • 73
    • 56449097446 scopus 로고    scopus 로고
    • Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration
    • Boutoille D, Féraille A, Maulaz D, Krempf M. Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration. Foot and Ankle International 2008;29:1074-8.
    • (2008) Foot and Ankle International , vol.29 , pp. 1074-1078
    • Boutoille, D.1    Féraille, A.2    Maulaz, D.3    Krempf, M.4
  • 76
  • 77
    • 70350580526 scopus 로고    scopus 로고
    • Microvascular dysfunction in diabetic foot disease and ulceration
    • Chao CY, Cheing GL. Microvascular dysfunction in diabetic foot disease and ulceration. Diabetes/Metabolism Research and Reviews 2009;25:604-14.
    • (2009) Diabetes/Metabolism Research and Reviews , vol.25 , pp. 604-614
    • Chao, C.Y.1    Cheing, G.L.2
  • 78
    • 37749001159 scopus 로고    scopus 로고
    • Standardising outcomes for clinical trials and systematic reviews
    • Clarke M. Standardising outcomes for clinical trials and systematic reviews. Trials 2007;8:39.
    • (2007) Trials , vol.8 , pp. 39
    • Clarke, M.1
  • 79
    • 49349087552 scopus 로고    scopus 로고
    • Comprehensive Meta-Analysis Sofware
    • 2.2.064. Englewood, NJ: Biostat, Inc,
    • Comprehensive Meta-Analysis team. Comprehensive Meta-Analysis Sofware. 2.2.064. Englewood, NJ: Biostat, Inc, 2011.
    • (2011)
  • 80
    • 84893345162 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections
    • Cruciani M, Lipsky BA, Mengoli C, de Lalla F. Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections. Cochrane Database of Systematic Reviews 2009, Issue 3. [DOI: 10.1002/14651858.CD006810]
    • (2009) Cochrane Database of Systematic Reviews , Issue.3
    • Cruciani, M.1    Lipsky, B.A.2    Mengoli, C.3    de Lalla, F.4
  • 81
    • 39049085750 scopus 로고    scopus 로고
    • Basic science of wound healing
    • Enoch S, Leaper DJ. Basic science of wound healing. Surgery 2008;26(2):31-7.
    • (2008) Surgery , vol.26 , Issue.2 , pp. 31-37
    • Enoch, S.1    Leaper, D.J.2
  • 82
    • 85041736641 scopus 로고    scopus 로고
    • Regranex (becaplermin) Gel
    • (accessed 6 July 2011)
    • Food, Drug Administration. Regranex (becaplermin) Gel. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm094968.htm (accessed 6 July 2011).
  • 85
    • 84865480225 scopus 로고    scopus 로고
    • Getting the methods right -the foundation of patient-centered outcomes research
    • Gabriel SE, Normand SL. Getting the methods right -the foundation of patient-centered outcomes research. The New England Journal of Medicine 2012;367(9):787-90.
    • (2012) The New England Journal of Medicine , vol.367 , Issue.9 , pp. 787-790
    • Gabriel, S.E.1    Normand, S.L.2
  • 86
    • 33749142760 scopus 로고    scopus 로고
    • Chemokines, cytokines, and growth factors in keratinocytes and dermal endothelial cells in the margin of chronic diabetic foot ulcers
    • Galkowska H, Wojewodzka U, Olszewski WL. Chemokines, cytokines, and growth factors in keratinocytes and dermal endothelial cells in the margin of chronic diabetic foot ulcers. Wound Repair and Regeneration 2006;14:558-65.
    • (2006) Wound Repair and Regeneration , vol.14 , pp. 558-565
    • Galkowska, H.1    Wojewodzka, U.2    Olszewski, W.L.3
  • 87
    • 0038051077 scopus 로고    scopus 로고
    • An economic evaluation of the cost of diabetic foot ulcers: results of a retrospective study on 239 patients
    • Girod I, Valensi P, Laforêt C, Moreau-Defarges T, Guillon P, Baron F. An economic evaluation of the cost of diabetic foot ulcers: results of a retrospective study on 239 patients. Diabetes and Metabolism 2003;29:269-77.
    • (2003) Diabetes and Metabolism , vol.29 , pp. 269-277
    • Girod, I.1    Valensi, P.2    Laforêt, C.3    Moreau-Defarges, T.4    Guillon, P.5    Baron, F.6
  • 91
  • 99
    • 84871262970 scopus 로고    scopus 로고
    • GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes
    • Guyatt G, Oxman AD, Sultan S, Brozek J, Glasziou P, Alonso-Coello P, et al. GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes. Journal of Clinical Epidemiology 2013;66(2):151-7.
    • (2013) Journal of Clinical Epidemiology , vol.66 , Issue.2 , pp. 151-157
    • Guyatt, G.1    Oxman, A.D.2    Sultan, S.3    Brozek, J.4    Glasziou, P.5    Alonso-Coello, P.6
  • 100
    • 77953026050 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of medical intervention in patients with early detection of diabetic foot in a tertiary care hospital in Bangladesh
    • Habib SH, Biswas KB, Akter S, Saha S, Ali L. Cost-effectiveness analysis of medical intervention in patients with early detection of diabetic foot in a tertiary care hospital in Bangladesh. Journal of Diabetes and its Complications 2010;24(4):259-64.
    • (2010) Journal of Diabetes and its Complications , vol.24 , Issue.4 , pp. 259-264
    • Habib, S.H.1    Biswas, K.B.2    Akter, S.3    Saha, S.4    Ali, L.5
  • 101
    • 34547982937 scopus 로고    scopus 로고
    • A systematic review on the impact of leg ulceration on patients' quality of life
    • Herber OR, Schnepp W, Rieger MA. A systematic review on the impact of leg ulceration on patients' quality of life. Health and Quality of Life Outcomes 2007;25:44.
    • (2007) Health and Quality of Life Outcomes , vol.25 , pp. 44
    • Herber, O.R.1    Schnepp, W.2    Rieger, M.A.3
  • 103
    • 84887346660 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions
    • Version 5.1.0 [updated March 2011]
    • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from www.cochrane-handbook.org.
    • The Cochrane Collaboration
    • Higgins, J.P.T.1    Green, S.2
  • 105
    • 0033546995 scopus 로고    scopus 로고
    • What is meant by intention to treat analysis? Survey of published randomised controlled trials
    • Hollis S, Campbell F. What is meant by intention to treat analysis? Survey of published randomised controlled trials. BMJ 1999;319(7211):670-4.
    • (1999) BMJ , vol.319 , Issue.7211 , pp. 670-674
    • Hollis, S.1    Campbell, F.2
  • 106
    • 0029950556 scopus 로고    scopus 로고
    • Diabetes and nontraumatic lower extremity amputations. Incidence, risk factors, and prevention -a 12-year follow-up study in Nauru
    • Humphrey AR, Dowse GK, Thoma K, Zimmet PZ. Diabetes and nontraumatic lower extremity amputations. Incidence, risk factors, and prevention -a 12-year follow-up study in Nauru. Diabetes Care 1996;19:710-4.
    • (1996) Diabetes Care , vol.19 , pp. 710-714
    • Humphrey, A.R.1    Dowse, G.K.2    Thoma, K.3    Zimmet, P.Z.4
  • 108
    • 34548118797 scopus 로고    scopus 로고
    • The association between baseline characteristics and the outcome of foot lesions in a UK population with diabetes
    • Ince P, Kendrick D, Game F, Jeffcoate W. The association between baseline characteristics and the outcome of foot lesions in a UK population with diabetes. Diabetic Medicine 2007;24:977-81.
    • (2007) Diabetic Medicine , vol.24 , pp. 977-981
    • Ince, P.1    Kendrick, D.2    Game, F.3    Jeffcoate, W.4
  • 109
    • 48649088109 scopus 로고    scopus 로고
    • Use of the SINBAD classification system and score in comparing outcome of foot ulcer management on three continents
    • Ince P, Abbas ZG, Lutale JK, Basit A, Ali SM, Chohan F, et al. Use of the SINBAD classification system and score in comparing outcome of foot ulcer management on three continents. Diabetes Care 2008;31:964-7.
    • (2008) Diabetes Care , vol.31 , pp. 964-967
    • Ince, P.1    Abbas, Z.G.2    Lutale, J.K.3    Basit, A.4    Ali, S.M.5    Chohan, F.6
  • 111
    • 85171879180 scopus 로고    scopus 로고
    • Meta-research: the art of getting it wrong
    • Ioannidis JP. Meta-research: the art of getting it wrong. Research Synthesis Methods 2010;1(3-4):169-84.
    • (2010) Research Synthesis Methods , vol.1 , Issue.3-4 , pp. 169-184
    • Ioannidis, J.P.1
  • 114
  • 115
    • 12944321365 scopus 로고    scopus 로고
    • Amputation as a marker of the quality of foot care in diabetes
    • Jeffcoate WJ, van Houtum WH. Amputation as a marker of the quality of foot care in diabetes. Diabetologia 2004;47:2051-8.
    • (2004) Diabetologia , vol.47 , pp. 2051-2058
    • Jeffcoate, W.J.1    van Houtum, W.H.2
  • 116
    • 18844416344 scopus 로고    scopus 로고
    • The incidence of amputation in diabetes
    • Jeffcoate WJ. The incidence of amputation in diabetes. Acta Chirurgica Belgica 2005;105:140-2.
    • (2005) Acta Chirurgica Belgica , vol.105 , pp. 140-142
    • Jeffcoate, W.J.1
  • 118
    • 0037264859 scopus 로고    scopus 로고
    • 'Loss of self': a psychosocial study of the quality of life of adults with diabetic foot ulceration
    • Kinmond K, McGee P, Gough S, Ashford R. 'Loss of self': a psychosocial study of the quality of life of adults with diabetic foot ulceration. Journal of Tisssue Viability 2003;13:6-8, 10, 12.
    • (2003) Journal of Tisssue Viability , vol.13 , pp. 6-12
    • Kinmond, K.1    McGee, P.2    Gough, S.3    Ashford, R.4
  • 119
    • 77949680683 scopus 로고    scopus 로고
    • The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews
    • Kirkham JJ, Dwan KM, Altman DG, Gamble C, Dodd S, Smyth R, et al. The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ 2010;340:c365.
    • (2010) BMJ , vol.340
    • Kirkham, J.J.1    Dwan, K.M.2    Altman, D.G.3    Gamble, C.4    Dodd, S.5    Smyth, R.6
  • 121
  • 122
    • 77952793213 scopus 로고    scopus 로고
    • Analysis of patient cost for recombinant human platelet-derived growth factor therapy as the first-line treatment of the insured patient with a diabetic foot ulcer
    • Lantis JC 2nd, Boone D, Gendics C, Todd G. Analysis of patient cost for recombinant human platelet-derived growth factor therapy as the first-line treatment of the insured patient with a diabetic foot ulcer. Advances in Skin and Wound Care 2009;22:167-71.
    • (2009) Advances in Skin and Wound Care , vol.22 , pp. 167-171
    • Lantis, J.C.1    Boone, D.2    Gendics, C.3    Todd, G.4
  • 124
    • 38149103485 scopus 로고    scopus 로고
    • Reevaluating the way we classify the diabetic foot: restructuring the diabetic foot risk classification system of the International Working Group on the Diabetic Foot
    • Lavery LA, Peters EJ, Williams JR, Murdoch DP, Hudson A, Lavery DC, International Working Group on the Diabetic Foot. Reevaluating the way we classify the diabetic foot: restructuring the diabetic foot risk classification system of the International Working Group on the Diabetic Foot. Diabetes Care 2008;31:154-6.
    • (2008) Diabetes Care , vol.31 , pp. 154-156
    • Lavery, L.A.1    Peters, E.J.2    Williams, J.R.3    Murdoch, D.P.4    Hudson, A.5    Lavery, D.C.6
  • 126
    • 0027180681 scopus 로고
    • Lower-extremity amputation. Incidence, risk factors, and mortality in the Oklahoma Indian Diabetes Study
    • Lee JS, Lu M, Lee VS, Russell D, Bahr C, Lee ET. Lower-extremity amputation. Incidence, risk factors, and mortality in the Oklahoma Indian Diabetes Study. Diabetes 1993;42:876-82.
    • (1993) Diabetes , vol.42 , pp. 876-882
    • Lee, J.S.1    Lu, M.2    Lee, V.S.3    Russell, D.4    Bahr, C.5    Lee, E.T.6
  • 127
    • 84883710616 scopus 로고    scopus 로고
    • Searching for studies
    • Higgins JPT, Green S (editors), Version 5.0.1 (updated March 2011). The Cochrane Collaboration
    • Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions
    • Lefebvre, C.1    Manheimer, E.2    Glanville, J.3
  • 128
    • 0029954662 scopus 로고    scopus 로고
    • Risk factors predicting lower extremity amputations in patients with NIDDM
    • Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Risk factors predicting lower extremity amputations in patients with NIDDM. Diabetes Care 1996;19:607-12.
    • (1996) Diabetes Care , vol.19 , pp. 607-612
    • Lehto, S.1    Rönnemaa, T.2    Pyörälä, K.3    Laakso, M.4
  • 129
    • 29344475960 scopus 로고    scopus 로고
    • Factors associated with diabetic patients at high risk for foot ulceration
    • Leymarie F, Richard JL, Malgrange D. Factors associated with diabetic patients at high risk for foot ulceration. Diabetes and Metabolism 2005;31:603-5.
    • (2005) Diabetes and Metabolism , vol.31 , pp. 603-605
    • Leymarie, F.1    Richard, J.L.2    Malgrange, D.3
  • 131
    • 84858828953 scopus 로고    scopus 로고
    • 'Time is of the essence'. PCORI moves to implement comparative effectiveness research, funding
    • McKinney M. 'Time is of the essence'. PCORI moves to implement comparative effectiveness research, funding. Modern Healthcare 2012; Vol. 42, issue 5:12-3.
    • (2012) Modern Healthcare , vol.42 , Issue.5 , pp. 12-13
    • McKinney, M.1
  • 134
    • 77950273246 scopus 로고    scopus 로고
    • CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials
    • Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ 2010;340:c869.
    • (2010) BMJ , vol.340
    • Moher, D.1    Hopewell, S.2    Schulz, K.F.3    Montori, V.4    Gotzsche, P.C.5    Devereaux, P.J.6
  • 135
    • 0030188411 scopus 로고    scopus 로고
    • Long-term incidence of lower-extremity amputations in a diabetic population
    • Moss SE, Klein R, Klein BE. Long-term incidence of lower-extremity amputations in a diabetic population. Archives of Family Medicine 1996;5:391-8.
    • (1996) Archives of Family Medicine , vol.5 , pp. 391-398
    • Moss, S.E.1    Klein, R.2    Klein, B.E.3
  • 138
    • 0034494502 scopus 로고    scopus 로고
    • Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration
    • O'Meara S, Cullum N, Majid M, Sheldon T. Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration. Health Technology Assessment 2000;4(21):1-237.
    • (2000) Health Technology Assessment , vol.4 , Issue.21 , pp. 1-237
    • O'Meara, S.1    Cullum, N.2    Majid, M.3    Sheldon, T.4
  • 139
    • 0035083550 scopus 로고    scopus 로고
    • The effects of ulcer size and site, patient's age, sex and type and duration of diabetes on the outcome of diabetic foot ulcers
    • Oyibo SO, Jude EB, Tarawneh I, Nguyen HC, Armstrong DG, Harkless LB. The effects of ulcer size and site, patient's age, sex and type and duration of diabetes on the outcome of diabetic foot ulcers. Diabetic Medicine 2001;18:133-8.
    • (2001) Diabetic Medicine , vol.18 , pp. 133-138
    • Oyibo, S.O.1    Jude, E.B.2    Tarawneh, I.3    Nguyen, H.C.4    Armstrong, D.G.5    Harkless, L.B.6
  • 140
    • 33847005383 scopus 로고    scopus 로고
    • Growth factors in the treatment of diabetic foot ulcers: new technologies, any promises?
    • Papanas N, Maltezos E. Growth factors in the treatment of diabetic foot ulcers: new technologies, any promises?. The International Journal of Lower Extremity Wounds 2007;6:37-53.
    • (2007) The International Journal of Lower Extremity Wounds , vol.6 , pp. 37-53
    • Papanas, N.1    Maltezos, E.2
  • 141
    • 47849085516 scopus 로고    scopus 로고
    • Becaplermin gel in the treatment of diabetic neuropathic foot ulcers
    • Papanas N, Maltezos E. Becaplermin gel in the treatment of diabetic neuropathic foot ulcers. Clinical Interventions in Aging 2008;3:233-40.
    • (2008) Clinical Interventions in Aging , vol.3 , pp. 233-240
    • Papanas, N.1    Maltezos, E.2
  • 142
    • 77952815052 scopus 로고    scopus 로고
    • Benefit-risk assessment of becaplermin in the treatment of diabetic foot ulcers
    • Papanas N, Maltezos E. Benefit-risk assessment of becaplermin in the treatment of diabetic foot ulcers. Drug Safety 2010;33(6):455-61.
    • (2010) Drug Safety , vol.33 , Issue.6 , pp. 455-461
    • Papanas, N.1    Maltezos, E.2
  • 143
    • 84935026550 scopus 로고    scopus 로고
    • Preliminary draft methodology report: 'Our questions, our decisions: Standards for patient-centered outcomes research'
    • (accessed 2 August 2012)
    • Patient-Centered Outcomes Research Institute (PCORI). Preliminary draft methodology report: 'Our questions, our decisions: Standards for patient-centered outcomes research'. http://www.pcori.org/assets/Preliminary-Draft-Methodology-Report.pdf (accessed 2 August 2012).
  • 146
    • 3943083467 scopus 로고    scopus 로고
    • The diabetic foot: quality of life
    • Price P. The diabetic foot: quality of life. Clinical Infectious Diseases 2004;39(Suppl 2):129-31.
    • (2004) Clinical Infectious Diseases , vol.39 , pp. 129-131
    • Price, P.1
  • 147
    • 38149042748 scopus 로고    scopus 로고
    • Reduced vascular endothelial growth factor expression and intra-epidermal nerve fiber loss in human diabetic neuropathy
    • Quattrini C, Jeziorska M, Boulton AJ, Malik RA. Reduced vascular endothelial growth factor expression and intra-epidermal nerve fiber loss in human diabetic neuropathy. Diabetes Care 2008;31:140-5.
    • (2008) Diabetes Care , vol.31 , pp. 140-145
    • Quattrini, C.1    Jeziorska, M.2    Boulton, A.J.3    Malik, R.A.4
  • 150
    • 11244252336 scopus 로고    scopus 로고
    • Diabetic foot ulcers and amputations: estimates of health utility for use in cost-effectiveness analyses of new treatments
    • Redekop WK, Stolk EA, Kok E, Lovas K, Kalo Z, Busschbach JJ. Diabetic foot ulcers and amputations: estimates of health utility for use in cost-effectiveness analyses of new treatments. Diabetes and Metabolism 2004;30:549-56.
    • (2004) Diabetes and Metabolism , vol.30 , pp. 549-556
    • Redekop, W.K.1    Stolk, E.A.2    Kok, E.3    Lovas, K.4    Kalo, Z.5    Busschbach, J.J.6
  • 151
    • 54149116782 scopus 로고    scopus 로고
    • A longitudinal study of patients with diabetes and foot ulcers and their health-related quality of life: wound healing and quality-of-life changes
    • Ribu L, Birkeland K, Hanestad BR, Moum T, Rustoen T. A longitudinal study of patients with diabetes and foot ulcers and their health-related quality of life: wound healing and quality-of-life changes. Journal of Diabetes Complications 2008;22:400-7.
    • (2008) Journal of Diabetes Complications , vol.22 , pp. 400-407
    • Ribu, L.1    Birkeland, K.2    Hanestad, B.R.3    Moum, T.4    Rustoen, T.5
  • 152
    • 52449103047 scopus 로고    scopus 로고
    • Épidémiologie du pied diabétique
    • Richard JL, Schuldiner S. Epidemiology of diabetic foot problems [Épidémiologie du pied diabétique]. La Revue Médicine Interne 2008;29(Suppl 2):222-30.
    • (2008) La Revue Médicine Interne , vol.29 , pp. 222-230
    • Richard, J.L.1    Schuldiner, S.2
  • 153
    • 0026648996 scopus 로고
    • Identifying diabetic patients at high risk for lower-extremity amputation in a primary health care setting. A prospective evaluation of simple screening criteria
    • Rith-Najarian SJ, Stolusky T, Gohdes DM. Identifying diabetic patients at high risk for lower-extremity amputation in a primary health care setting. A prospective evaluation of simple screening criteria. Diabetes Care 1992;15:1386-9.
    • (1992) Diabetes Care , vol.15 , pp. 1386-1389
    • Rith-Najarian, S.J.1    Stolusky, T.2    Gohdes, D.M.3
  • 154
  • 155
    • 2642513872 scopus 로고    scopus 로고
    • Diabetic foot ulcer classification system for research purposes: a progress report on criteria for including patients in research studies
    • Schaper NC. Diabetic foot ulcer classification system for research purposes: a progress report on criteria for including patients in research studies. Diabetes/Metabolism Research and Reviews 2004;20(Suppl 1):90-5.
    • (2004) Diabetes/Metabolism Research and Reviews , vol.20 , pp. 90-95
    • Schaper, N.C.1
  • 156
    • 84866405164 scopus 로고    scopus 로고
    • Reducing lower leg amputations in diabetes: a challenge for patients, healthcare providers and the healthcare system
    • Schaper NC, Apelqvist J, Bakker K. Reducing lower leg amputations in diabetes: a challenge for patients, healthcare providers and the healthcare system. Diabetologia 2012;55(7):1869-72.
    • (2012) Diabetologia , vol.55 , Issue.7 , pp. 1869-1872
    • Schaper, N.C.1    Apelqvist, J.2    Bakker, K.3
  • 157
    • 84856142553 scopus 로고    scopus 로고
    • Diagnosis and treatment of peripheral arterial disease in diabetic patients with a foot ulcer. A progress report of the International Working Group on the Diabetic Foot
    • Schaper NC, Andros G, Apelqvist J, Bakker K, Lammer J, Lepantalo M, et al. Diagnosis and treatment of peripheral arterial disease in diabetic patients with a foot ulcer. A progress report of the International Working Group on the Diabetic Foot. Diabetes/Metabolism Research and Reviews 2012;28(Suppl 1):218-24.
    • (2012) Diabetes/Metabolism Research and Reviews , vol.28 , pp. 218-224
    • Schaper, N.C.1    Andros, G.2    Apelqvist, J.3    Bakker, K.4    Lammer, J.5    Lepantalo, M.6
  • 158
    • 77953685708 scopus 로고    scopus 로고
    • CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials
    • Schulz KF, Altman DG, Moher D, CONSORT Group. CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials. Journal of Clinical Epidemiology 2010;63(8):834-40.
    • (2010) Journal of Clinical Epidemiology , vol.63 , Issue.8 , pp. 834-840
    • Schulz, K.F.1    Altman, D.G.2    Moher, D.3
  • 159
    • 84859864850 scopus 로고    scopus 로고
    • The Patient-Centered Outcomes Research Institute (PCORI) national priorities for research and initial research agenda
    • Selby JV, Beal AC, Frank L. The Patient-Centered Outcomes Research Institute (PCORI) national priorities for research and initial research agenda. JAMA 2012;307(15):1583-4.
    • (2012) JAMA , vol.307 , Issue.15 , pp. 1583-1584
    • Selby, J.V.1    Beal, A.C.2    Frank, L.3
  • 160
    • 33748272307 scopus 로고    scopus 로고
    • Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial
    • Sheehan P, Jones P, Giurini JM, Caselli A, Veves A. Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial. Plastic and Reconstructive Surgery 2006;117(7 Suppl):239-44.
    • (2006) Plastic and Reconstructive Surgery , vol.117 , Issue.7 , pp. 239-244
    • Sheehan, P.1    Jones, P.2    Giurini, J.M.3    Caselli, A.4    Veves, A.5
  • 162
    • 84870715654 scopus 로고    scopus 로고
    • Search filters
    • (accessed 12 March 2010)
    • Scottish Intercollegiate Guidelines Network (SIGN). Search filters. http://www.sign.ac.uk/methodology/filters.html#random (accessed 12 March 2010).
  • 165
  • 167
    • 79961238388 scopus 로고    scopus 로고
    • Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
    • Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, Lau J, et al. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ 2011;343:d4002.
    • (2011) BMJ , vol.343
    • Sterne, J.A.1    Sutton, A.J.2    Ioannidis, J.P.3    Terrin, N.4    Jones, D.R.5    Lau, J.6
  • 168
    • 64149103180 scopus 로고    scopus 로고
    • Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
    • Szabo C. Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction. British Journal of Pharmacology 2009;156:713-27.
    • (2009) British Journal of Pharmacology , vol.156 , pp. 713-727
    • Szabo, C.1
  • 171
    • 44949246559 scopus 로고    scopus 로고
    • Amputations and ulceration; pitfalls in assessing incidence
    • Van Houtum WH. Amputations and ulceration; pitfalls in assessing incidence. Diabetes/Metabolism Research and Reviews 2008;24(Suppl 1):14-8.
    • (2008) Diabetes/Metabolism Research and Reviews , vol.24 , pp. 14-18
    • Van Houtum, W.H.1
  • 172
    • 0026717848 scopus 로고
    • The risk of foot ulceration in diabetic patients with high foot pressure: a prospective study
    • Veves A, Murray HJ, Young MJ, Boulton AJ. The risk of foot ulceration in diabetic patients with high foot pressure: a prospective study. Diabetologia 1992;35:660-3.
    • (1992) Diabetologia , vol.35 , pp. 660-663
    • Veves, A.1    Murray, H.J.2    Young, M.J.3    Boulton, A.J.4
  • 174
    • 33748338753 scopus 로고    scopus 로고
    • TM 150) in healing diabetic foot ulcers
    • TM 150) in healing diabetic foot ulcers. Wounds 2006;18:186-96.
    • (2006) Wounds , vol.18 , pp. 186-196
    • Viswanathan, V.1    Pendsey, S.2
  • 175
    • 0019803407 scopus 로고
    • The dysvascular foot: a system of diagnosis and treatment
    • Wagner FW. The dysvascular foot: a system of diagnosis and treatment. Foot and Ankle International 1981;2:64-122.
    • (1981) Foot and Ankle International , vol.2 , pp. 64-122
    • Wagner, F.W.1
  • 177
    • 0031681266 scopus 로고    scopus 로고
    • Clinical efficacy of becaplermin (rhPDGF-BB) gel. Becaplermin Gel Studies Group
    • [PUBMED: 9777976]
    • Wieman TJ. Clinical efficacy of becaplermin (rhPDGF-BB) gel. Becaplermin Gel Studies Group. American Journal of Surgery 1998;176(2A Suppl):74S-9S. [PUBMED: 9777976]
    • (1998) American Journal of Surgery , vol.176 , pp. 74S-79S
    • Wieman, T.J.1
  • 178
    • 14844350326 scopus 로고    scopus 로고
    • Health related quality of life, cognitive function, and depression in diabetic patients with foot ulcer or amputation. A preliminary study
    • Willrich A, Pinzur M, McNeil M, Juknelis D, Lavery L. Health related quality of life, cognitive function, and depression in diabetic patients with foot ulcer or amputation. A preliminary study. Foot and Ankle International 2005;26:128-34.
    • (2005) Foot and Ankle International , vol.26 , pp. 128-134
    • Willrich, A.1    Pinzur, M.2    McNeil, M.3    Juknelis, D.4    Lavery, L.5
  • 179
    • 35448958494 scopus 로고    scopus 로고
    • Risk factors associated with adverse outcomes in a population-based prospective cohort study of people with their first diabetic foot ulcer
    • Winkley K, Stahl D, Chalder T, Edmonds ME, Ismail K. Risk factors associated with adverse outcomes in a population-based prospective cohort study of people with their first diabetic foot ulcer. Journal of Diabetes and its Complications 2007;21:341-9.
    • (2007) Journal of Diabetes and its Complications , vol.21 , pp. 341-349
    • Winkley, K.1    Stahl, D.2    Chalder, T.3    Edmonds, M.E.4    Ismail, K.5
  • 180
    • 3442894442 scopus 로고    scopus 로고
    • Diabetic heel ulcers: a major risk factor for lower extremity amputation
    • Younes NA, Albsoul AM, Awad H. Diabetic heel ulcers: a major risk factor for lower extremity amputation. Ostomy/Wound Management 2004;50:50-60.
    • (2004) Ostomy/Wound Management , vol.50 , pp. 50-60
    • Younes, N.A.1    Albsoul, A.M.2    Awad, H.3
  • 181
    • 0028237931 scopus 로고
    • The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study
    • Young MJ, Breddy JL, Veves A, Boulton AJ. The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study. Diabetes Care 1994;17:557-60.
    • (1994) Diabetes Care , vol.17 , pp. 557-560
    • Young, M.J.1    Breddy, J.L.2    Veves, A.3    Boulton, A.J.4
  • 182
    • 70049111701 scopus 로고    scopus 로고
    • Software for data transformation for time-to-event outcomes (alfa version)
    • Valencia: Universidad de Carabobo,
    • Zavala D, Martí-Carvajal A, Peña-Marti G, Comunián-Carrasco G. Software for data transformation for time-to-event outcomes (alfa version). Valencia: Universidad de Carabobo, 2007.
    • (2007)
    • Zavala, D.1    Martí-Carvajal, A.2    Peña-Marti, G.3    Comunián-Carrasco, G.4


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