A phase III study to evaluate the safety and efficacy of recombinant human epidermal growth factor (REGEN-D™ 150) in healing diabetic foot ulcers

Wounds

Volumn 18, Issue 7, 2006, Pages 186-196

  Viswanathan, Vijay ^a   Pendsey, Sharad ^b   Sekar, N ^c   Murthy, G S R ^d,e  

^a Diabetes Research Centre Tamil Nadu   (India)

^b Diabetes Clinic and Research Centre   (India)

^c APOLLO HOSPITALS   (India)

^d INDIAN STATISTICAL INSTITUTE   (India)

^e Bharat Biotech International Limited   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748338753     PISSN: 10447946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Palumbo PJ, Melton LJ. Peripheral vascular disease in diabetes. In: Harris MI, Hamman RF, eds. Diabetes in America. Bethesda, Md: National Diabetes Data Group; 1985:1-21. NIH Pub. No. 85-1468.
2. Frykberg RG. Epidemiology of the diabetic foot: ulcerations and amputations. Adv Wound Care. 1999;12(3):139-141.
3. Robson MC. Exogenous growth factor application effect on human wound healing. Progress in Dermatology. 1996;30(3):1-7.
4. Miettinen PJ, Warburton D, Bu D, et al. Impaired lung branching morphogenesis in the absence of functional EGF receptor. Dev Biology. 1997;186(2):224-236.
5. Bonassar LJ, Trippel SB. Interaction of epidermal growth factor and insulin-like growth factor-I in the regulation of growth plate chondrocytes. Exp Cell Res. 1997;234(1):1-6.
6. Larijani B, Afshari M, Fadaei M, Pajouhi M, Bastanhagh MH, Baradar Jalili R. Effect of local epidermal growth factor on wound healing in diabetic foot. Irn J Endocrinol Metab. 2003;5(2):(SN 18).
7. Tsang MW, Wong WK, Hung CS, et al. Human epidermal growth factor enhances healing of diabetic foot ulcers. Diabetes Care. 2003;26(6):1856-1861.
8. Laato M. The effect of epidermal growth factor on granulation tissue formation in the rat. Acta Chir Scand Suppl. 1988;546:1-44.