-
1
-
-
79952232216
-
Global cancer statistics
-
PID: 21296855
-
Jemal, A. et al. Global cancer statistics. CA Cancer J Clin61:69–90 (2011).
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
-
2
-
-
57349095906
-
Th International Epidemiology of Lung Cancer: geographical distribution and secular trends
-
PID: 18670299
-
Youlden, D. R., Cramb, S. M. & Baade, P. D. Th International Epidemiology of Lung Cancer: geographical distribution and secular trends. J Thorac Oncol3:819–831 (2008).
-
(2008)
J Thorac Oncol
, vol.3
, pp. 819-831
-
-
Youlden, D.R.1
Cramb, S.M.2
Baade, P.D.3
-
3
-
-
44249086425
-
Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship
-
PID: 18452692
-
Molina, J. R., Yang, P., Cassivi, S. D., Schild, S. E. & Adjei, A. A. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc83:584–594 (2008).
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 584-594
-
-
Molina, J.R.1
Yang, P.2
Cassivi, S.D.3
Schild, S.E.4
Adjei, A.A.5
-
4
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BD28XhtlWqsbzI, PID: 17167137
-
Sandler, A. et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med355:2542–2550 (2006).
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
-
5
-
-
49049089802
-
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BD1cXpvVWmtLg%3D, PID: 18506025
-
Scagliotti, G. V. et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol26:3543–3551 (2008).
-
(2008)
J Clin Oncol
, vol.26
, pp. 3543-3551
-
-
Scagliotti, G.V.1
-
6
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BD38Xkt1OlsQ%3D%3D, PID: 11784875
-
Schiller, J. H. et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med346:92–98 (2002).
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
-
7
-
-
84975247285
-
Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells
-
COI: 1:CAS:528:DC%2BC2MXhslWlu7fK, PID: 26492363
-
Seah, S. et al. Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells. Cell Death Dis6:e1926 (2015).
-
(2015)
Cell Death Dis
, vol.6
, pp. e1926
-
-
Seah, S.1
-
8
-
-
0033523874
-
Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death
-
COI: 1:CAS:528:DyaK1MXnslKrsb8%3D, PID: 10597216
-
Lee, J. H. et al. Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene18:6183–6190 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 6183-6190
-
-
Lee, J.H.1
-
9
-
-
84863283179
-
BAG3: a new therapeutic target of human cancers?
-
COI: 1:CAS:528:DC%2BC38XivFyjs74%3D, PID: 22237703
-
Zhu, H., Liu, P. & Li, J. BAG3: a new therapeutic target of human cancers? Histol Histopathol27:257–261 (2012).
-
(2012)
Histol Histopathol
, vol.27
, pp. 257-261
-
-
Zhu, H.1
Liu, P.2
Li, J.3
-
10
-
-
79960008971
-
BAG 3: a multifaceted protein that regulates major cell pathways
-
COI: 1:STN:280:DC%2BC3MvhsFyltQ%3D%3D, PID: 21472004
-
Rosati, A., Graziano, V. De Laurenzi, V., Pascale, M. & Turco, M. C. BAG 3: a multifaceted protein that regulates major cell pathways. Cell Death Dis2:e141 (2011).
-
(2011)
Cell Death Dis
, vol.2
, pp. e141
-
-
Rosati, A.1
Graziano, V.2
De Laurenzi, V.3
Pascale, M.4
Turco, M.C.5
-
11
-
-
77955664680
-
Down-modulation o Bis sensitizes cell death in C6 glioma cells induced by oxygen-glucose deprivation
-
COI: 1:CAS:528:DC%2BC3cXpsFektrg%3D, PID: 20599823
-
Jung, S. E. et al. Down-modulation o Bis sensitizes cell death in C6 glioma cells induced by oxygen-glucose deprivation. Brain Res1349:1–10 (2010).
-
(2010)
Brain Res
, vol.1349
, pp. 1-10
-
-
Jung, S.E.1
-
12
-
-
0037621432
-
BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis
-
COI: 1:CAS:528:DC%2BD3sXivFGhtL0%3D, PID: 12700638
-
Romano, M. F. et al. BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis. Cell Death Differ10:383–385 (2003).
-
(2003)
Cell Death Differ
, vol.10
, pp. 383-385
-
-
Romano, M.F.1
-
13
-
-
58149494120
-
BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis
-
COI: 1:CAS:528:DC%2BD1MXotlKmug%3D%3D, PID: 19111544
-
Liu, P., Xu, B., Li, J. & Lu, H. BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis. FEBS Lett583:401–406 (2009).
-
(2009)
FEBS Lett
, vol.583
, pp. 401-406
-
-
Liu, P.1
Xu, B.2
Li, J.3
Lu, H.4
-
14
-
-
66149118221
-
HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins
-
COI: 1:CAS:528:DC%2BD1MXjs1ymsr8%3D, PID: 19179333
-
Jacobs, A. T. & Marnett, L. J. HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. J Biol Chem284:9176–9183 (2009).
-
(2009)
J Biol Chem
, vol.284
, pp. 9176-9183
-
-
Jacobs, A.T.1
Marnett, L.J.2
-
15
-
-
33947542628
-
The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand
-
COI: 1:CAS:528:DC%2BD2sXjtlGmsLg%3D, PID: 17164298
-
Chiappetta, G. et al. The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand. J Clin Endocrinol Metab92:1159–1163 (2007).
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1159-1163
-
-
Chiappetta, G.1
-
16
-
-
84884588730
-
PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells
-
COI: 1:CAS:528:DC%2BC38XhsFyjsr7O, PID: 23108398
-
Li, N. et al. PKCdelta-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells. Oncogene32:4539–4548 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 4539-4548
-
-
Li, N.1
-
17
-
-
79959376413
-
BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy
-
COI: 1:CAS:528:DC%2BC3MXoslOgu7o%3D, PID: 21561597
-
Festa, M. et al. BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy. Am J Pathol178:2504–2512 (2011).
-
(2011)
Am J Pathol
, vol.178
, pp. 2504-2512
-
-
Festa, M.1
-
18
-
-
84868122918
-
Expression of the antiapoptotic protein BAG 3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival
-
COI: 1:CAS:528:DC%2BC38XhslOltbrJ, PID: 22944597
-
Rosati, A. et al. Expression of the antiapoptotic protein BAG 3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am J Pathol181:1524–1529 (2012).
-
(2012)
Am J Pathol
, vol.181
, pp. 1524-1529
-
-
Rosati, A.1
-
19
-
-
84880222772
-
BAG3 is a novel serum biomarker for pancreatic adenocarcinomas
-
COI: 1:CAS:528:DC%2BC3sXhtVKrsrjP, PID: 23821002
-
Falco, A. et al. BAG3 is a novel serum biomarker for pancreatic adenocarcinomas. Am J Gastroenterol108:1178–1180 (2013).
-
(2013)
Am J Gastroenterol
, vol.108
, pp. 1178-1180
-
-
Falco, A.1
-
20
-
-
84946220080
-
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages
-
COI: 1:CAS:528:DC%2BC2MXhslOgtb3F, PID: 26522614
-
Rosati, A. et al. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages. Nat Commun6:8695 (2015).
-
(2015)
Nat Commun
, vol.6
, pp. 8695
-
-
Rosati, A.1
-
21
-
-
84855271324
-
Bag3 promotes resistance to apoptosis through Bcl-2 family members in non-small cell lung cancer
-
PID: 21971866
-
Zhang, Y., Wang, J. H., Lu, Q. & Wang, Y. J. Bag3 promotes resistance to apoptosis through Bcl-2 family members in non-small cell lung cancer. Oncol Rep27:109–113 (2012).
-
(2012)
Oncol Rep
, vol.27
, pp. 109-113
-
-
Zhang, Y.1
Wang, J.H.2
Lu, Q.3
Wang, Y.J.4
-
22
-
-
84907069899
-
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth
-
PID: 25149536
-
Chiappetta, G. et al. The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth. Oncotarget5:6846–6853 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 6846-6853
-
-
Chiappetta, G.1
-
23
-
-
84952872146
-
Bis Expression in Patients with Surgically Resected Lung Cancer and its Clinical Significance
-
PID: 25968616
-
Yeo, C. D. et al. Bis Expression in Patients with Surgically Resected Lung Cancer and its Clinical Significance. Ann Surg Oncol22(suppl 3):1365–1370 (2015).
-
(2015)
Ann Surg Oncol
, vol.22
, Issue.3
, pp. 1365-1370
-
-
Yeo, C.D.1
-
24
-
-
0141841845
-
Chromosomal variations within aneuploid cancer lines
-
COI: 1:CAS:528:DC%2BD3sXnvFGrtbs%3D, PID: 14500702
-
Isaka, T., Nestor, A. L., Takada, T. & Allison, D. C. Chromosomal variations within aneuploid cancer lines. J Histochem Cytochem51:1343–1353 (2003).
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 1343-1353
-
-
Isaka, T.1
Nestor, A.L.2
Takada, T.3
Allison, D.C.4
-
25
-
-
78751505781
-
KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter
-
COI: 1:CAS:528:DC%2BC3MXlsFSmsA%3D%3D, PID: 21078672
-
Yoon, Y. J. et al. KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter. J Biol Chem286: 1737–1747 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 1737-1747
-
-
Yoon, Y.J.1
-
26
-
-
84956672129
-
Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737
-
Mani, J. et al. Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737. World J Urol (2015).
-
(2015)
World J Urol
-
-
Mani, J.1
-
27
-
-
84910002928
-
BAG3 promoted starvation-induced apoptosis of thyroid cancer cells via attenuation of autophagy
-
Li, S. et al. BAG3 promoted starvation-induced apoptosis of thyroid cancer cells via attenuation of autophagy. J Clin Endocrinol Metab99:E2298–2307 (2014).
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. 2298-2307
-
-
Li, S.1
-
28
-
-
84885755564
-
BAG3 sensitizes cancer cells exposed to DNA damaging agents via direct interaction with GRP78
-
COI: 1:CAS:528:DC%2BC3sXhvVWnsrnN, PID: 24080088
-
Kong, D. H. et al. BAG3 sensitizes cancer cells exposed to DNA damaging agents via direct interaction with GRP78. Biochim Biophys Acta1833: 3245–3253 (2013).
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3245-3253
-
-
Kong, D.H.1
-
29
-
-
84874817068
-
The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737
-
COI: 1:CAS:528:DC%2BC3sXjslegsLc%3D, PID: 23341456
-
Boiani, M., Daniel, C., Liu, X., Hogarty, M. D. & Marnett, L. J. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem288:6980–6990 (2013).
-
(2013)
J Biol Chem
, vol.288
, pp. 6980-6990
-
-
Boiani, M.1
Daniel, C.2
Liu, X.3
Hogarty, M.D.4
Marnett, L.J.5
-
30
-
-
77951878281
-
AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer
-
PID: 20354451
-
Moretti, L., Li, B., Kim, K. W., Chen, H. & Lu, B. AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer. J Thorac Oncol5:680–687 (2010).
-
(2010)
J Thorac Oncol
, vol.5
, pp. 680-687
-
-
Moretti, L.1
Li, B.2
Kim, K.W.3
Chen, H.4
Lu, B.5
-
31
-
-
84893162249
-
Autophagy inhibition enhances pan-Bcl-2 inhibitor AT-101-induced apoptosis in non-small cell lung cancer
-
COI: 1:CAS:528:DC%2BC2cXhtFKkt7jO, PID: 24299314
-
Mei, H., Lin, Z., Wang, Y., Wu, G. & Song, Y. Autophagy inhibition enhances pan-Bcl-2 inhibitor AT-101-induced apoptosis in non-small cell lung cancer. Neoplasma61:186–192 (2014).
-
(2014)
Neoplasma
, vol.61
, pp. 186-192
-
-
Mei, H.1
Lin, Z.2
Wang, Y.3
Wu, G.4
Song, Y.5
-
32
-
-
84933037483
-
Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer
-
PID: 26089640
-
Ren, T. et al. Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer. Drug Des Devel Ther9:2887–2910 (2015).
-
(2015)
Drug Des Devel Ther
, vol.9
, pp. 2887-2910
-
-
Ren, T.1
-
33
-
-
0034726071
-
In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins
-
COI: 1:CAS:528:DC%2BD3cXltVGrsbk%3D, PID: 10922472
-
Akgul, C., Moulding, D. A., White, M. R. & Edwards, S. W. In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins. FEBS Lett478:72–76 (2000).
-
(2000)
FEBS Lett
, vol.478
, pp. 72-76
-
-
Akgul, C.1
Moulding, D.A.2
White, M.R.3
Edwards, S.W.4
-
34
-
-
84943542776
-
Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application
-
COI: 1:CAS:528:DC%2BC2MXht1Cht7rP, PID: 26222334
-
An, S., He, D., Wagner, E. & Jiang, C. Peptide-lik Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application. Small11:5142–5150 (2015).
-
(2015)
Small
, vol.11
, pp. 5142-5150
-
-
An, S.1
He, D.2
Wagner, E.3
Jiang, C.P.-L.4
-
35
-
-
84949999070
-
Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing
-
COI: 1:CAS:528:DC%2BC2MXhvVOqt73M, PID: 26646625
-
Wang, B. K. et al. Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing. Biomaterials78:27–39 (2016).
-
(2016)
Biomaterials
, vol.78
, pp. 27-39
-
-
Wang, B.K.1
-
36
-
-
42949179530
-
Bag3 gene expression is regulated by heat shock factor 1
-
COI: 1:CAS:528:DC%2BD1cXlvVKgt7w%3D, PID: 18286539
-
Franceschelli, S. et al. Bag3 gene expression is regulated by heat shock factor 1. J Cell Physiol215:575–577 (2008).
-
(2008)
J Cell Physiol
, vol.215
, pp. 575-577
-
-
Franceschelli, S.1
-
37
-
-
58149375078
-
Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1
-
COI: 1:CAS:528:DC%2BD1MXit1KhtLw%3D, PID: 19006120
-
Du, Z. X. et al. Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1. J Cell Physiol218:631–637 (2009).
-
(2009)
J Cell Physiol
, vol.218
, pp. 631-637
-
-
Du, Z.X.1
-
38
-
-
84910124257
-
Bis i Induced by Oxidative Stress via Activation of HSF1
-
COI: 1:CAS:528:DC%2BC2cXitVGmtbjE, PID: 25352760
-
Yoo, H. J., Im, C. N., Youn, D. Y., Yun, H. H. & Lee, J. H. Bis i Induced by Oxidative Stress via Activation of HSF1. Korean J Physiol Pharmacol18:403–409 (2014).
-
(2014)
Korean J Physiol Pharmacol
, vol.18
, pp. 403-409
-
-
Yoo, H.J.1
Im, C.N.2
Youn, D.Y.3
Yun, H.H.4
Lee, J.H.5
-
39
-
-
80052830376
-
Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes
-
COI: 1:CAS:528:DC%2BC3MXht1SisLjE, PID: 21775628
-
Zhang, X. & Qian, S. B. Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes. Mol Biol Cell22:3277–3288 (2011).
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3277-3288
-
-
Zhang, X.1
Qian, S.B.2
-
40
-
-
79959939343
-
BAG3 and friends: co-chaperones in selective autophagy during aging and disease
-
COI: 1:CAS:528:DC%2BC38XhtFCisb8%3D, PID: 21681022
-
Behl, C. BAG3 and friends: co-chaperones in selective autophagy during aging and disease. Autophagy7:795–798 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 795-798
-
-
Behl, C.1
-
41
-
-
84901659516
-
2,4-Bis(4-hydroxybenzyl)phenol inhibits heat shock transcription factor 1 and sensitizes lung cancer cells to conventional anticancer modalities
-
COI: 1:CAS:528:DC%2BC2cXmsVGlurk%3D, PID: 24746225
-
Yoon, T., Kang, G. Y., Han, A. R., Seo, E. K. & Lee, Y. S. 2,4-Bis(4-hydroxybenzyl)phenol inhibits heat shock transcription factor 1 and sensitizes lung cancer cells to conventional anticancer modalities. J Nat Prod77:1123–1129 (2014).
-
(2014)
J Nat Prod
, vol.77
, pp. 1123-1129
-
-
Yoon, T.1
Kang, G.Y.2
Han, A.R.3
Seo, E.K.4
Lee, Y.S.5
-
42
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
COI: 1:CAS:528:DC%2BC2cXjvFajsA%3D%3D, PID: 24157548
-
Ran, F. A. et al. Genome engineering using the CRISPR-Cas9 system. Nat Protoc8:2281–2308 (2013).
-
(2013)
Nat Protoc
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
|