Evaluation of automated multi-parametric indirect immunofluorescence assays to detect anti-neutrophil cytoplasmic antibodies (ANCA) in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)

Autoimmunity Reviews

Volumn 15, Issue 7, 2016, Pages 736-741

  Csernok, Elena ^a   Damoiseaux, Jan ^b   Rasmussen, Niels ^c   Hellmich, Bernhard ^a   van Paassen, Pieter ^b   Vermeersch, Pieter ^d,e   Blockmans, Daniel ^d   Cohen Tervaert, Jan Willem ^f   Bossuyt, Xavier ^d,e  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c STATENS SERUM INSTITUT   (Denmark)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY OF LEUVEN   (Belgium)

^f MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Anti neutrophil cytoplasmic antibodies (ANCA); Granulomatosis with polyangiitis (GPA); Indirect immunofluorescence; Microscopic polyangiitis (MPA)

Indexed keywords

MYELOBLASTIN; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANTIBODY DETECTION; ANTIGEN SPECIFICITY; AUTOMATION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE ASSAY KIT; IMMUNOFLUORESCENCE TEST; MAJOR CLINICAL STUDY; MICROSCOPIC POLYANGIITIS; RECEIVER OPERATING CHARACTERISTIC; REVIEW; SENSITIVITY AND SPECIFICITY; WEGENER GRANULOMATOSIS; CLINICAL TRIAL; IMMUNOLOGY; INDIRECT FLUORESCENT ANTIBODY TECHNIQUE; MULTICENTER STUDY; PROCEDURES;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GRANULOMATOSIS WITH POLYANGIITIS; HUMANS; MICROSCOPIC POLYANGIITIS;

EID: 84962106254     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2016.03.010     Document Type: Review

References (14)

1. Cohen Tervaert J.W., Damoiseaux J. Antineutrophil cytoplasmic autoantibodies: how are they detected and what is their use for diagnosis, classification and followup?. Clin Rev Allergy Immunol 2012, 43:211-219.
2. Radice A., Bianchi L., Sinico R.A. Anti-neutrophil cytoplasmic autoantibodies: methodological aspects and clinical significance in systemic vasculitis. Autoimmun Rev 2013, 12:487-495.
3. Csernok E., Moosig F. Current and emerging techniques for ANCA detection in vasculitis. Nat Rev Rheumatol 2014, 10:494-501.
4. Savige J., Gillis D., Benson E., Davies D., Esnault V., Falk R.J., et al. International consensus statement on testing and reporting of antineutrophil cytoplasmic antibodies (ANCA). Am J Clin Pathol 1999, 111:507-513.
5. Damoiseaux J., Steller U., Buschtez M., et al. EuroPLUS ANCA BIOCHIP mosaic: PR3 and MPO antigen microdots improve the laboratory diagnostics of ANCA-associated vasculitis. J Immunol Methods 2009, 348:67-73.
6. Sowa M., Grossmann K., Knütter I., Hiemann R., Röber N., Anderer U., et al. Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA. PLoS One 2014, 9.
7. Krause C., Ens K., Fechner K., Voigt J., Fraune J., Rohwäder E., et al. EuroPattern suite technology for computer-aided immunofluorescence microscopy in autoantibody diagnostics. Lupus 2015, 24:516-529.
8. Wiik A., Rasmussen N., Wieslander J. Methods to detect autoantibodies to neutrophilic granulocytes. Manual Biol Markers Dis. 1993, A9:1-14.
9. Knütter I., Hiemann R., Brumma T., Büttner T., Großmann K., Cusini M., et al. Automated interpretation of ANCA patterns-a new approach in the serology of ANCA-associated vasculitis. Arthritis Res Ther 2012, 14:R271.
10. Damoiseaux J., Mallet K., Vaessen M., Austen J., Cohen Tervaert J.W. Automatic reading of ANCA-slides: evaluation of the AKLIDES system. Clin Dev Immunol 2012, 2012:762-774.
11. Pollock W., Clarke K., Gallagher K., Hall J., Luckhurst E., McEvoy R., et al. Immunofluorescent patterns produced by antineutrophil cytoplasmic antibodies (ANCA) vary depending on neutrophil substrate and conjugate. J Clin Pathol 2002, 55:680-683.
12. Savige J., Dimech W., Fritzler M., Goeken J., Hagen E.C., Jennette J.C., et al. International Group for Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies (ANCA). Addendum to the International Consensus Statement on testing and reporting of antineutrophil cytoplasmic antibodies. Quality control guidelines, comments, and recommendations for testing in other autoimmune diseases. Am J Clin Pathol 2003, 120:312-318.
13. Choi H.K., Liu S., Merkel P.A., Colditz G.A., Niles J.L. Diagnostic performance of antineutrophil cytoplasmic antibody tests for idiopathic vasculitides: metaanalysis with a focus on antimyeloperoxidase antibodies. J Rheumatol 2001, 28:1584-1590.
14. Avery T.Y., Bons J., Van Paassen P., Damoiseaux J. Diagnostic ANCA algorithms in daily clinical practice: evidence, experience, and effectiveness. Lupus 2016, [in press].