Antimicrobial resistance profiles and genetic elements involved in carbapenem resistance in Acinetobacter baumannii isolates from a referral hospital in Southern Iran

Journal of Global Antimicrobial Resistance

Volumn 5, Issue , 2016, Pages 75-79

  Alaei, Najmeh ^a   Aziemzadeh, Masoud ^b   Bahador, Abbas ^c  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b BUSHEHR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acinetobacter baumannii; blaOXA genes; CarbAcineto NP test; Carbapenem resistance; ISAba

Indexed keywords

BETA LACTAMASE; CARBAPENEM; CARBAPENEMASE; CEFEPIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; DOXYCYCLINE; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MINOCYCLINE; NETILMICIN; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TIGECYCLINE; TIMENTIN; TOBRAMYCIN; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIUM ISOLATE; BACTERIUM ISOLATION; BETA LACTAMASEOXA GENE; BROTH DILUTION; CONTROLLED STUDY; DISK DIFFUSION; ENZYME SYNTHESIS; GENE INSERTION SEQUENCE; IRAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; TERTIARY CARE CENTER; ACINETOBACTER INFECTION; DRUG EFFECT; GENETICS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ANTI-BACTERIAL AGENTS; CARBAPENEMS; DRUG RESISTANCE, BACTERIAL; HUMANS; IRAN; MICROBIAL SENSITIVITY TESTS;

EID: 84962070964     PISSN: 22137165     EISSN: 22137173     Source Type: Journal    
DOI: 10.1016/j.jgar.2015.12.005     Document Type: Article

References (20)

1. [1] Bahador, A., Raoofian, R., Taheri, M., Pourakbari, B., Hashemizadeh, Z., Hashemi, F.B., Multidrug resistance among Acinetobacter baumannii isolates from Iran: changes in antimicrobial susceptibility patterns and genotypic profile. Microb Drug Resist 20 (2014), 632–640.
2. [2] Antunes, L.C., Visca, P., Towner, K.J., Acinetobacter baumannii: evolution of a global pathogen. Pathog Dis 71 (2014), 292–301.
3. [3] Lin, M.F., Lan, C.Y., Antimicrobial resistance in Acinetobacter baumannii: from bench to bedside. World J Clin Cases 16:2 (2014), 787–814.
4. [4] Chittawatanarat, K., Jaipakdee, W., Chotirosniramit, N., Chandacham, K., Jirapongcharoenlap, T., Microbiology, resistance patterns, and risk factors of mortality in ventilator-associated bacterial pneumonia in a northern Thai tertiary-care university based general surgical intensive care unit. Infect Drug Resist 7 (2014), 203–210.
5. [5] Evans, B.A., Hamouda, A., Amyes, S.G., The rise of carbapenem-resistant Acinetobacter baumannii. Curr Pharm Des 19 (2013), 223–238.
6. [6] Moradi, J., Hashemi, F.B., Bahador, A., Antibiotic resistance of Acinetobacter baumannii in Iran: a systemic review of the published literature. Osong Public Health Res Perspect 6 (2015), 79–86.
7. [7] Magiorakos, A.P., Srinivasan, A., Carey, R., Carmeli, Y., Falagas, M.E., Giske, C.G., et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 18 (2012), 268–281.
8. [8] Higgins, P.G., Lehmann, M., Wisplinghoff, H., Seifert, H., gyrB multiplex PCR to differentiate between Acinetobacter calcoaceticus and Acinetobacter genomic species 3. J Clin Microbiol 48 (2010), 4592–4594.
9. [9] Clinical and Laboratory Standards Institute, Performance standards for antimicrobial susceptibility testing; twenty-fourth informational supplement. Document M100-S24. 2014, CLSI, Wayne, PA.
10. [10] European Committee on Antimicrobial Susceptibility Testing, Breakpoint tables for interpretation of MICs and zone diameters. Version 4.0. 2014 http://www.eucast.org/clinical_breakpoints [accessed 07.01.16].
11. [11] Dortet, L., Poirel, L., Errera, C., Nordmann, P., CarbAcineto, N.P., test for rapid detection of carbapenemase-producing Acinetobacter spp. J Clin Microbiol 52 (2014), 2359–2364.
12. [12] Higgins, P.G., Lehmann, M., Seifert, H., Inclusion of OXA-143 primers in a multiplex polymerase chain reaction (PCR) for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents, 35, 2010, 305.
13. [13] Villalón, P., Valdezate, S., Medina-Pascual, M.J., Carrasco, G., Vindel, A., Saez-Nieto, J.A., Epidemiology of the Acinetobacter-derived cephalosporinase, carbapenem-hydrolysing oxacillinase and metallo-β-lactamase genes, and of common insertion sequences, in epidemic clones of Acinetobacter baumannii from Spain. J Antimicrob Chemother 68 (2013), 550–553.
14. [14] Bahador, A., Taheri, M., Pourakbari, B., Hashemizadeh, Z., Rostami, H., Mansoori, N., et al. Emergence of rifampicin, tigecycline, and colistin-resistant Acinetobacter baumannii in Iran; Spreading of MDR strains of novel International Clone variants. Microb Drug Resist 19 (2013), 397–406.
15. [15] Li, J., Nation, R.L., Owen, R.J., Wong, S., Spelman, D., Franklin, C., Antibiograms of multidrug-resistant clinical Acinetobacter baumannii: promising therapeutic options for treatment of infection with colistin-resistant strains. Clin Infect Dis 45 (2007), 594–598.
16. [16] Pournaras, S., Poulou, A., Dafopoulou, K., Chabane, Y.N., Kristo, I., Makris, D., et al. Growth retardation, reduced invasiveness, and impaired colistin-mediated cell death associated with colistin resistance development in Acinetobacter baumannii. Antimicrob Agents Chemother 58 (2014), 828–832.
17. [17] Kempf, M., Rolain, J.M., Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: clinical impact and therapeutic options. Int J Antimicrob Agents 39 (2012), 105–114.
18. [18] Fournier, P.E., Richet, H., Weinstein, R.A., The epidemiology and control of Acinetobacter baumannii in health care facilities. Clin Infect Dis 42 (2006), 692–699.
19. [19] Walther-Rasmussen, J., Høiby, N., OXA-type carbapenemases. J Antimicrob Chemother 57 (2006), 373–383.
20. [20] D'Arezzo, S., Principe, L., Capone, A., Petrosillo, N., Petrucca, A., Visca, P., Changing carbapenemase gene pattern in an epidemic multidrug-resistant Acinetobacter baumannii lineage causing multiple outbreaks in central Italy. J Antimicrob Chemother 66 (2011), 54–61.