A prospective pilot investigation of brain volume, white matter hyperintensities, and hemorrhagic lesions after mild traumatic brain injury

Frontiers in Neurology

Volumn 7, Issue FEB, 2016, Pages

  Jarrett, Michael ^a   Tam, Roger ^a   Hernández Torres, Enedino ^a   Martin, Nancy ^b,c,d   Perera, Warren ^e   Zhao, Yinshan ^a   Shahinfard, Elham ^a   Dadachanji, Shiroy ^a   Taunton, Jack ^a   Li, David K B ^a   Rauscher, Alexander ^a,f  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Richmond Hospital   (Canada)

^c Burnaby Hospital   (Canada)

^d Delta Hospital   (Canada)

^e ST VINCENT S HOSPITAL   (Australia)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Brain volume; Concussion; MRI; mTBI; Neuroimaging; Susceptibility weighted imaging; White matter hyperintensities

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRAIN CONCUSSION; BRAIN DAMAGE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE SEVERITY; FEMALE; GRAY MATTER; HUMAN; ICE HOCKEY; MALE; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; PILOT STUDY; PROSPECTIVE STUDY; RADIOLOGICAL PARAMETERS; SPORT INJURY; SUSCEPTIBILITY WEIGHTED IMAGING; THREE DIMENSIONAL IMAGING; TRAUMATIC BRAIN INJURY; WHITE MATTER HYPERINTENSITY; WHITE MATTER INJURY; YOUNG ADULT;

EID: 84962024907     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2016.00011     Document Type: Article

References (36)

1. Feigin VL, Theadom A, Barker-Collo S, Starkey NJ, McPherson K, Kahan M, et al. Incidence of traumatic brain injury in New Zealand: a population-based study. Lancet Neurol (2013) 12:53-64. doi: 10.1016/S1474-4422(12)70262-4.
2. Ryu WHA, Feinstein A, Colantonio A, Streiner DL, Dawson DR. Early identification and incidence of mild TBI in Ontario. Can J Neurol Sci (2009) 36:429-35. doi:10.1017/S0317167100007745.
3. Tong KA, Ashwal S, Holshouser BA, Shutter LA, Herigault G, Haacke EM, et al. Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology (2003) 227:332-9. doi:10.1148/radiol.2272020176.
4. McCrory P, Meeuwisse WH, Aubry M, Cantu B, Dvorak J, Echemendia RJ, et al. Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012. Br J Sports Med (2013) 47:250-8. doi:10.1136/bjsports-2013-092313.
5. Wilson D, Charidimou A, Werring DJ. Advances in understanding spontaneous intracerebral hemorrhage: insights from neuroimaging. Expert Rev Neurother (2014) 14:661-78. doi:10.1586/14737175.2014.918506.
6. Hartwigsen G, Siebner HR, Deuschl G, Jansen O, Ulmer S. Incidental findings are frequent in young healthy individuals undergoing magnetic resonance imaging in brain research imaging studies: a prospective single-center study. J Comput Assist Tomogr (2010) 34:596-600. doi:10.1097/RCT.0b013e3181d9c2bb.
7. Zhou Y, Kierans A, Kenul D, Ge Y, Rath J, Reaume J, et al. Mild traumatic brain injury: longitudinal regional brain volume changes. Radiology (2013) 267:880-90. doi:10.1148/radiol.13122542.
8. Denk C, Rauscher A. Susceptibility weighted imaging with multiple echoes. J Magn Reson Imaging (2010) 31:185-91. doi:10.1002/jmri.21995.
9. Valovich McLeod TC, Register-Mihalik JK. Clinical outcomes assessment for the management of sport-related concussion. J Sport Rehabil (2011) 20:46-60.
10. Gunter JL, Bernstein MA, Borowski BJ, Ward CP, Britson PJ, Felmlee JP, et al. Measurement of MRI scanner performance with the ADNI phantom. Med Phys (2009) 36:2193-205. doi:10.1118/1.3116776.
11. Lancaster JL, Woldorff MG, Parsons LM, Liotti M, Freitas CS, Rainey L, et al. Automated Talairach atlas labels for functional brain mapping. Hum Brain Mapp (2000) 10:120-31. doi:10.1002/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8.
12. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage (2002) 17:825-41. doi:10.1006/nimg.2002.1132.
13. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal (2001) 5:143-56. doi:10.1016/S1361-8415(01)00036-6.
14. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TEJ, Johansen-Berg H, et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage (2004) 23(Suppl 1):S208-19. doi:10.1016/j.neuroimage.2004.07.051.
15. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp (2002) 17:143-55. doi:10.1002/hbm.10062.
16. Bates D, Maechler M, Bolker B, Walker S. lme4: Linear Mixed-Effects Models Using Eigen and S4 (2014). Available from: http://CRAN.R-project.org/package=lme4.
17. Baayen RH. Analyzing Linguistic Data: A Practical Introduction to Statistics Using R. Cambridge; New York: Cambridge University Press (2008).
18. Zagorchev L, Meyer C, Stehle T, Wenzel F, Young S, Peters J, et al. Differences in regional brain volumes two months and one year after mild traumatic brain injury. J Neurotrauma (2015) 33:29-34. doi:10.1089/neu.2014.3831.
19. Guskiewicz KM, Register-Mihalik J, McCrory P, McCrea M, Johnston K, Makdissi M, et al. Evidence-based approach to revising the SCAT2: introducing the SCAT3. Br J Sports Med (2013) 47:289-93. doi:10.1136/bjsports-2013-092225.
20. Duning T, Kloska S, Steinsträter O, Kugel H, Heindel W, Knecht S. Dehydration confounds the assessment of brain atrophy. Neurology (2005) 64:548-50. doi:10.1212/01.WNL.0000150542.16969.CC.
21. Kempton MJ, Ettinger U, Schmechtig A, Winter EM, Smith L, McMorris T, et al. Effects of acute dehydration on brain morphology in healthy humans. Hum Brain Mapp (2009) 30:291-8. doi:10.1002/hbm.20500.
22. Watson P, Head K, Pitiot A, Morris P, Maughan RJ. Effect of exercise and heat-induced hypohydration on brain volume. Med Sci Sports Exerc (2010) 42:2197-204. doi:10.1249/MSS.0b013e3181e39788.
23. Biller A, Reuter M, Patenaude B, Homola GA, Breuer F, Bendszus M, et al. Responses of the human brain to mild dehydration and rehydration explored in vivo by 1H-MR imaging and spectroscopy. AJNR Am J Neuroradiol (2015) 36:2277-84. doi:10.3174/ajnr.A4508.
24. Wilcox BJ, Machan JT, Beckwith JG, Greenwald RM, Burmeister E, Crisco JJ. Head-impact mechanisms in men's and women's collegiate ice hockey. J Athl Train (2014) 49:514-20. doi:10.4085/1062-6050-49.3.19.
25. Koennecke H-C. Cerebral microbleeds on MRI: prevalence, associations, and potential clinical implications. Neurology (2006) 66:165-71. doi:10.1212/01.wnl.0000194266.55694.1e.
26. Hopkins RO, Beck CJ, Burnett DL, Weaver LK, Victoroff J, Bigler ED. Prevalence of white matter hyperintensities in a young healthy population. J Neuroimaging (2006) 16:243-51. doi:10.1111/j.1552-6569.2006.00047.x.
27. Wiggermann V, Hernandez-Torres E, Traboulsee A, Li DKB, Rauscher A. FLAIR2: A combination of FLAIR and T2 for improved MS lesion detection. AJNR Am J Neuroradiol (2015). doi:10.3174/ajnr.A4514.
28. Bigler ED. Neuropathology of mild traumatic brain injury: correlation to neurocognitive and neurobehavioral findings. In: Kobeissy FH, editor. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects Frontiers in Neuroengineering. Boca Raton, FL: CRC Press; Taylor & Francis (2015). p. 433-50.
29. Gentry LR, Godersky JC, Thompson B. MR imaging of head trauma: review of the distribution and radiopathologic features of traumatic lesions. AJR Am J Roentgenol (1988) 150:663-72. doi:10.2214/ajr.150.3.663.
30. McKee AC, Stein TD, Nowinski CJ, Stern RA, Daneshvar DH, Alvarez VE, et al. The spectrum of disease in chronic traumatic encephalopathy. Brain (2013) 136:43-64. doi:10.1093/brain/aws307.
31. Omalu BI, DeKosky ST, Minster RL, Kamboh MI, Hamilton RL, Wecht CH. Chronic traumatic encephalopathy in a National Football League player. Neurosurgery (2005) 57:128-34. doi:10.1227/01.NEU.0000163407.92769.ED.
32. Omalu B, Bailes J, Hamilton RL, Kamboh MI, Hammers J, Case M, et al. Emerging histomorphologic phenotypes of chronic traumatic encephalopathy in American athletes. Neurosurgery (2011) 69:173-83. doi:10.1227/NEU.0b013e318212bc7b.
33. McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, et al. Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol (2009) 68:709-35. doi:10.1097/NEN.0b013e3181a9d503.
34. Davenport EM, Whitlow CT, Urban JE, Espeland MA, Jung Y, Rosenbaum DA, et al. Abnormal white matter integrity related to head impact exposure in a season of high school varsity football. J Neurotrauma (2014) 31(19):1617-24. doi:10.1089/neu.2013.3233.
35. McAllister TW, Ford JC, Flashman LA, Maerlender A, Greenwald RM, Beckwith JG, et al. Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes. Neurology (2014) 82:63-9. doi:10.1212/01.wnl.0000438220.16190.42.
36. Murugavel M, Cubon V, Putukian M, Echemendia R, Cabrera J, Osherson D, et al. Longitudinal diffusion tensor imaging study assessing white matter fiber tracts after sports-related concussion. J Neurotrauma (2014) 31:1860-71. doi:10.1089/neu.2014.3368.