Kidney and aging — A narrative review

Experimental Gerontology

Volumn 87, Issue , 2017, Pages 153-155

  Gekle, Michael ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN II; CREATININE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOKINE; ERYTHROPOIETIN; FIBROBLAST GROWTH FACTOR 23; GROWTH FACTOR; KLOTHO PROTEIN; POTASSIUM ION; PROTEIN P21; SODIUM ION; POTASSIUM; SODIUM;

ACID BASE BALANCE; AGING; APOPTOSIS; CHRONIC INFLAMMATION; CREATININE BLOOD LEVEL; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; KIDNEY PERFUSION; KIDNEY PLASMA FLOW; KIDNEY TUBULE ABSORPTION; KIDNEY VASCULAR RESISTANCE; MACROPHAGE; MICTURITION; NEPHRON; OXIDATIVE STRESS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SODIUM RETENTION; URINE OSMOLALITY; VITAMIN D METABOLISM; CARDIOVASCULAR DISEASE; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGING; CARDIOVASCULAR DISEASES; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; POTASSIUM; RENIN-ANGIOTENSIN SYSTEM; SODIUM;

EID: 84961958942     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2016.03.013     Document Type: Review

References (24)

1. Alshaer, I.M., Kilbride, H.S., Stevens, P.E., Eaglestone, G., Knight, S., Carter, J.L., Delaney, M.P., Farmer, C.K.T., Irving, J., O'Riordan, S.E., Dalton, R.N., Lamb, E.J., External validation of the Berlin equations for estimation of GFR in the elderly. Am. J. Kidney Dis. 63 (2014), 862–865.
2. Bolignano, D., Mattace-Raso, F., Sijbrands, E.J.G., Zoccali, C., The aging kidney revisited: a systematic review. Ageing Res. Rev. 14 (2014), 65–80.
3. Erdely, A., Greenfeld, Z., Wagner, L., Baylis, C., Sexual dimorphism in the aging kidney: effects on injury and nitric oxide system. Kidney Int. 63 (2003), 1021–1026.
4. Famulski, K.S., Halloran, P.F., Molecular events in kidney ageing. Curr. Opin. Nephrol. Hypertens. 14 (2005), 243–248.
5. Fliser, D., Franek, E., Joest, M., Block, S., Mutschler, E., Ritz, E., Renal function in the elderly: impact of hypertension and cardiac function. Kidney Int. 51 (1997), 1196–1204.
6. Frassetto, L.A., Morris, R.C. Jr., Sebastian, A., Effect of age on blood acid–base composition in adult humans: role of age-related renal functional decline. Am. J. Phys. 271 (1996), F1114–F1122.
7. Gekle, M., Renal tubule albumin transport. Annu. Rev. Physiol. 67 (2005), 573–594.
8. Hill, G.S., Heudes, D., Jacquot, C., Gauthier, E., Bariety, J., Morphometric evidence for impairment of renal autoregulation in advanced essential hypertension. Kidney Int. 69 (2006), 823–831.
9. Hollenberg, N.K., Adams, D.F., Olomon, H.S., Rashid, A.B.D.U., Abrams, H.L., Merrill, J.P., Senescence and the renal vasculature in normal man. Circ. Res. 34 (1974), 309–316.
10. Huang, C.L., Moe, O., Klotho: a novel regulator of calcium and phosphorus homeostasis. Pflugers Arch. - Eur. J. Physiol. 462 (2011), 185–193.
11. Jiang, S., Sun, X., Gu, H., Chen, Y., Xi, C., Qiao, X., Chen, X., Age-related change in kidney function, its influencing factors, and association with asymptomatic carotid atherosclerosis in healthy individuals — a 5-year follow-up study. Maturitas 73 (2012), 230–238.
12. Kilbride, H.S., Stevens, P.E., Eaglestone, G., Knight, S., Carter, J.L., Delaney, M.P., Farmer, C.K.T., Irving, J., O'Riordan, S.E., Dalton, R.N., Lamb, E.J., Accuracy of the MDRD (modification of diet in renal disease) study and CKD-EPI (CKD epidemiology collaboration) equations for estimation of GFR in the elderly. Am. J. Kidney Dis. 61 (2013), 57–66.
13. Koyama, D., Sato, Y., Aizawa, M., Maki, T., Kurosawa, M., Kuro-o, M., Furukawa, Y., Soluble sKlotho as a candidate for the biomarker of aging. Biochem. Biophys. Res. Commun. 467 (2015), 1019–1025.
14. Lindberg, K., Amin, R., Moe, O.W., Hu, M.C., Erben, R.G., Östman Wernerson, A., Lanske, B., Olauson, H., Larsson, T.E., The kidney is the principal organ mediating klotho effects. J. Am. Soc. Nephrol. 25 (2014), 2169–2175.
15. Lindeman, R.D., Goldman, R., Anatomic and physiologic age changes in the kidney. Exp. Gerontol. 21 (1986), 379–406.
16. Martin, J.E., Sheaff, M.T., Renal ageing. J. Pathol. 211 (2007), 198–205.
17. Reckelhoff, J.F., Zhang, H., Granger, J.P., Decline in renal hemodynamic function in aging SHR: role of androgens. Hypertension 30 (1997), 677–681.
18. Rowe, J.W., Shock, N.W., DeFronzo, R.A., The influence of age on the renal response to water deprivation in man. Nephron 17 (1976), 270–278.
19. Sands, J.M., Urine-concentrating ability in the aging kidney. Sci. Aging Knowl. Environ., 2003, 2003, E15.
20. Sands, J.M., Urine concentrating and diluting ability during aging. J. Gerontol. Ser. A Biol. Med. Sci. 67 (2012), 1352–1357.
21. Schaeffner, E.S., Ebert, N., Delanaye, P., Frei, U., Gaedeke, J., Jakob, O., Kuhlmann, M.K., Schuchardt, M., Tölle, M., Ziebig, R., van der Giet, M., Martus, P., Two novel equations to estimate kidney function in persons aged 70 years or older. Ann. Intern. Med. 157 (2012), 471–481.
22. Schmitt, R., Susnik, N., Melk, A., Molecular aspects of renal senescence. Curr. Opin. Organ. Transplant. 20 (2015), 412–416.
23. Yamada, H., Sacktor, B., Kinsella, J., Age-associated changes in ammoniagenesis in isolated rat renal tubule segments. Am. J. Phys. 262 (1992), F600–F605.
24. Zhou, X.J., Rakheja, D., Yu, X., Saxena, R., Vaziri, N.D., Silva, F.G., The aging kidney. Kidney Int. 74 (2008), 710–720.