Care-Delivery Interventions to Manage Agitation and Aggression in Dementia Nursing Home and Assisted Living Residents: A Systematic Review and Meta-analysis

Journal of the American Geriatrics Society

Volumn 64, Issue 3, 2016, Pages 477-488

  Jutkowitz, Eric ^a,b   Brasure, Michelle ^a,c   Fuchs, Erika ^a,b   Shippee, Tetyana ^a   Kane, Rosalie A ^a   Fink, Howard A ^c   Butler, Mary ^a,b   Sylvanus, Tonye ^a   Kane, Robert L ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

behavioral symptoms; dementia; nonpharmacological; nursing homes; psychosocial interventions

Indexed keywords

NEUROLEPTIC AGENT; PSYCHOTROPIC AGENT;

AGGRESSION; AGITATION; ASSISTED LIVING FACILITY; DEMENTIA; GERIATRIC CARE; HEALTH CARE DELIVERY; HUMAN; MEDICAL EDUCATION; MEDICAL STAFF; META ANALYSIS; NURSING HOME; NURSING HOME PATIENT; REVIEW; SYSTEMATIC REVIEW; AGED; COMPLICATION; DISEASE MANAGEMENT; EDUCATION; FEMALE; HOME FOR THE AGED; MALE; NURSING; NURSING STAFF; PATIENT CARE; PROCEDURES; PSYCHOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESTLESSNESS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGGRESSION; ASSISTED LIVING FACILITIES; DELIVERY OF HEALTH CARE; DEMENTIA; DISEASE MANAGEMENT; EPISODE OF CARE; FEMALE; HOMES FOR THE AGED; HUMANS; MALE; NURSING HOMES; NURSING STAFF; PSYCHOMOTOR AGITATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84961855474     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.13936     Document Type: Review

References (54)

1. Trivedi D, Goodman C, Dickinson A, et al., A protocol for a systematic review of research on managing behavioural and psychological symptoms in dementia for community-dwelling older people: Evidence mapping and syntheses. Syst Rev 2013; 2: 1-9.
2. Dementia Initiative. Dementia care: The quality Chasm 2013 [on-line]. Available at www.leadingage.org/uploadedFiles/Content/Members/Nursing-Homes/Quality/DementiaCareTheQualityChasm.pdf Accessed October 17, 2013.
3. Lyketsos CG, Carrillo MC, Ryan JM, et al., Neuropsychiatric symptoms in Alzheimer's disease. Alzheimers Dement 2011; 7: 532-539.
4. Cohen-Mansfield J,. Agitation in the elderly. Adv Psychosom Med 1989; 19: 101-113.
5. British Columbia Ministry of Health. Best Practice Guideline for Accommodating and Managing Behavioural and Psychological Symptoms of Dementia in Residential Care. Victoria, British Columbia, Canada: British Columbia Ministry of Health, 2011.
6. Cohen-Mansfield J,. Agitated behavior in persons with dementia: The relationship between type of behavior, its frequency, and its disruptiveness. J Psychiatr Res 2008; 43: 64-69.
7. Black W, Almeida OP,. A systematic review of the association between the behavioral and psychological symptoms of dementia and burden of care. Int Psychogeriatr 2004; 16: 295-315.
8. Ornstein K, Gaugler JE,. The problem with "problem behaviors": A systematic review of the association between individual patient behavioral and psychological symptoms and caregiver depression and burden within the dementia patient-caregiver dyad. Int Psychogeriatr 2012; 24: 1536-1552.
9. Pinquart M, Sorensen S,. Associations of stressors and uplifts of caregiving with caregiver burden and depressive mood: A meta-analysis. J Gerontol B Psychol Sci Soc Sci 2003; 58B: 112-128.
10. Bonner AF, Field TS, Lemay CA, et al., Rationales that providers and family members cited for the use of antipsychotic medications in nursing home residents with dementia. J Am Geriatr Soc 2015; 63: 302-308.
11. Briesacher BA, Limcangco M, Simoni-Wastila L, et al., The quality of antipsychotic drug prescribing in nursing homes. Arch Intern Med 2005; 165: 1280-1285.
12. Gill SS, Bronskill SE, Normand SL, et al., Antipsychotic drug use and mortality in older adults with dementia. Ann Intern Med 2007; 146: 775-786.
13. Schneider LS, Dagerman KS, Insel P,. Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials. JAMA 2005; 294: 1934-1943.
14. Schneider LS, Tariot PN, Dagerman KS, et al., Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med 2006; 355: 1525-1538.
15. Mitka M,. CMS seeks to reduce antipsychotic use in nursing home residents with dementia. JAMA 2012; 308: 119-121.
16. Salzman C, Jeste DV, Meyer RE, et al., Elderly patients with dementia-related symptoms of severe agitation and aggression: Consensus statement on treatment options, clinical trials methodology, and policy. J Clin Psychiatry 2008; 69: 889-898.
17. A. P. A. Work Group on Alzheimer's Disease and other Dementias, Rabins PV, Blacker D, Rovner BW, et al., American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition. Am J Psychiatry 2007; 164 (Suppl): 5-56.
18. Lyketsos CG, Colenda CC, Beck C, et al., Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry 2006; 14: 561-572.
19. Vernooij-Dassen M, Vasse E, Zuidema S, et al., Psychosocial interventions for dementia patients in long-term care. Int Psychogeriatr 2010; 22: 1121-1128.
20. Testad I, Corbett A, Aarsland D, et al., The value of personalized psychosocial interventions to address behavioral and psychological symptoms in people with dementia living in care home settings: A systematic review. Int Psychogeriatr 2014; 26: 1083-1098.
21. Seitz DP, Brisbin S, Herrmann N, et al., Efficacy and feasibility of nonpharmacological interventions for neuropsychiatric symptoms of dementia in long term care: A systematic review. J Am Med Dir Assoc 2012; 13: 503-506.
22. Livingston G, Kelly L, Lewis-Holmes E, et al., A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia. Health Technol Assess 2014; 18: 1-226.
23. Cabrera E, Sutcliffe C, Verbeek H, et al., Non-pharmacological interventions as a best practice strategy in people with dementia living in nursing homes. A systematic review. Eur Geriatr Med 2015; 6: 134-150.
24. Fu R, Gartlehner G, Grant M, et al., Conducting quantitative synthesis when comparing medical interventions: AHRQ and the Effective Health Care Program. J Clin Epidemiol 2011; 64: 1187-1197.
25. Owens DK, Lohr KN, Atkins D, et al., AHRQ series paper 5: Grading the strength of a body of evidence when comparing medical interventions-agency for healthcare research and quality and the effective health-care program. J Clin Epidemiol 2010; 63: 513-523.
26. Berkman ND, Lohr KN, Ansari M, et al., Grading the strength of a body of evidence when assessing health care interventions for the effective health care program of the Agency for Healthcare Research and Quality: An update. Rockville, MD: Agency for Healthcare Research and Quality November 2013.
27. Cornell JE, Mulrow CD, Localio R, et al., Random-effects meta-analysis of inconsistent effects: A time for change. Ann Intern Med 2014; 160: 267-270.
28. Chenoweth L, King MT, Jeon YH, et al., Caring for Aged Dementia Care Resident Study (CADRES) of person-centred care, dementia-care mapping, and usual care in dementia: A cluster-randomized trial. Lancet Neurol 2009; 8: 317-325.
29. Rokstad AM, Rosvik J, Kirkevold O, et al., The effect of person-centred dementia care to prevent agitation and other neuropsychiatric symptoms and enhance quality of life in nursing home patients: A 10-month randomized controlled trial. Dement Geriatr Cogn Disord 2013; 36: 340-353.
30. van de Ven G, Draskovic I, Adang EM, et al., Effects of dementia-care mapping on residents and staff of care homes: A pragmatic cluster-randomised controlled trial. PLoS ONE 2013; 8: e67325.
31. Ballard CG, O'Brien JT, Reichelt K, et al., Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: The results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry 2002; 63: 553-558.
32. Fossey J, Ballard C, Juszczak E, et al., Effect of enhanced psychosocial care on antipsychotic use in nursing home residents with severe dementia: Cluster randomised trial. BMJ 2006; 332: 756A-758A.
33. Rapp MA, Mell T, Majic T, et al., Agitation in nursing home residents with dementia (VIDEANT trial): Effects of a cluster-randomized, controlled, guideline implementation trial. J Am Med Dir Assoc 2013; 14: 690-695.
34. Zwijsen SA, Smalbrugge M, Eefsting JA, et al., Coming to grips with challenging behavior: A cluster randomized controlled trial on the effects of a multidisciplinary care program for challenging behavior in dementia. J Am Med Dir Assoc 2014; 15: 531-e1.
35. Finnema E, Droes RM, Ettema T, et al., The effect of integrated emotion-oriented care versus usual care on elderly persons with dementia in the nursing home and on nursing assistants: A randomized clinical trial. Int J Geriatr Psychiatry 2005; 20: 330-343.
36. Schrijnemaekers V, van Rossum E, Candel M, et al., Effects of emotion-oriented care on elderly people with cognitive impairment and behavioral problems. Int J Geriatr Psychiatry 2002; 17: 926-937.
37. Teri L, Huda P, Gibbons L, et al., STAR: A dementia-specific training program for staff in assisted living residences. Gerontologist 2005; 45: 686-693.
38. Deudon A, Maubourguet N, Gervais X, et al., Non-pharmacological management of behavioural symptoms in nursing homes. Int J Geriatr Psychiatry 2009; 24: 1386-1395.
39. Magai C, Cohen CI, Gomberg D,. Impact of training dementia caregivers in sensitivity to nonverbal emotion signals. Int Psychogeriatr 2002; 14: 25-38.
40. McCallion P, Toseland RW, Lacey D, et al., Educating nursing assistants to communicate more effectively with nursing home residents with dementia. Gerontologist 1999; 39: 546-558.
41. Proctor R, Burns A, Powell HS, et al., Behavioural management in nursing and residential homes: A randomized controlled trial. Lancet 1999; 354: 26-29.
42. Wenborn J, Challis D, Head J, et al., Providing activity for people with dementia in care homes: A cluster randomized controlled trial. Int J Geriatr Psychiatry 2013; 28: 1296-1304.
43. Clare L, Whitaker R, Woods RT, et al., AwareCare: A pilot randomized controlled trial of an awareness-based staff training intervention to improve quality of life for residents with severe dementia in long-term care settings. Int Psychogeriatr 2013; 25: 128-139.
44. Kovach CR, Logan BR, Noonan PE, et al., Effects of the Serial Trial Intervention on discomfort and behavior of nursing home residents with dementia. Am J Alzheimers Dis Other Demen 2006; 21: 147-155.
45. Chapman DG, Toseland RW,. Effectiveness of advanced illness care teams for nursing home residents with dementia. Soc Work 2007; 52: 321-329.
46. McGilton KS, Rivera TM, Dawson P,. Can we help persons with dementia find their way in a new environment? Aging Ment Health 2003; 7: 363-371.
47. Galik E, Resnick B, Hammersla M, et al., Optimizing function and physical activity among nursing home residents with dementia: Testing the impact of function-focused care. Gerontologist 2013; 54: 930-943.
48. Ballard CG, Waite J, Birks J,. Atypical antipsychotics for aggression and psychosis in Alzheimer's disease. Cochrane Database Syst Rev 2006; 1: CD003476.
49. Schneider LS, Dagerman K, Insel PS,. Efficacy and adverse effects of atypical antipsychotics for dementia: Meta-analysis of randomized, placebo-controlled trials. Am J Geriatr Psychiatry 2006; 14: 191-210.
50. Volicer L,. Toward better terminology of behavioral symptoms of dementia. J Am Med Dir Assoc 2012; 13: 3-4.
51. Rahman AN, Applebaum RA, Schnelle JF, et al., Translating research into practice in nursing homes: Can we close the gap? Gerontologist 2012; 52: 597-606.
52. Rahman AN, Schnelle JF,. The nursing home culture-change movement: Recent past, present, and future directions for research. Gerontologist 2008; 48: 142-148.
53. Schnelle JF, Alessi CA, Simmons SF, et al., Translating clinical research into practice: A randomized controlled trial of exercise and incontinence care with nursing home residents. J Am Geriatr Soc 2002; 50: 1476-1483.
54. Schrijnemaekers VJ, Van Rossum E, Candel MJ, et al., Effects of emotion-oriented care on work-related outcomes of professional caregivers in homes for elderly persons. J Gerontol B Psychol Sci Soc Sci 2003; 58B: S50-S57.