Leukocyte integrin αlβ2 headpiece structures: The αi domain, the pocket for the internal ligand, and concerted movements of its loops

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 11, 2016, Pages 2940-2945

  Springer, Timothy A ^a,b   Sen, Mehmet ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c University of Houston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAXBETA2 INTEGRIN; CD18 ANTIGEN; DISULFIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR 1; GLYCAN; GLYCOPROTEIN; INTEGRIN; INTEGRIN ALPHALBETA2; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; N GLYCAN; PYROGLUTAMIC ACID; SPECIFICITY DETERMINING LOOP 1; SPECIFICITY DETERMINING LOOP 2; UNCLASSIFIED DRUG; LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROTEIN BINDING;

ALLOSTERISM; ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; BETA CHAIN; CONTROLLED STUDY; CRYSTAL STRUCTURE; LEUKOCYTE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SUBUNIT; PROTEIN TRANSPORT; TILTING; ALLOSTERIC SITE; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; CONSENSUS SEQUENCE; HUMAN; MOLECULAR GENETICS; MOLECULAR MODEL; MOTION; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HUMANS; LEUKOCYTES; LIGANDS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84961828029     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601379113     Document Type: Article

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