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Volumn 23, Issue 12, 2015, Pages 746-748

Small Molecules Take A Big Step Against Clostridium difficile

Author keywords

Clostridium difficile; Ebselen; Inhibitor; Small molecule; TcdB

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL VACCINE; BEZLOTOXUMAB; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; EBSELEN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOXOID VACCINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT;

EID: 84961773547     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2015.10.009     Document Type: Short Survey
Times cited : (6)

References (7)
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    • Kuehne, S.A.1
  • 2
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    • Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death
    • Slater L.H., et al. Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. ACS Chem. Biol. 2013, 8:812-822.
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    • Slater, L.H.1
  • 3
    • 84923139085 scopus 로고    scopus 로고
    • Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage
    • Tam J., et al. Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage. Chem. Biol. 2015, 22:175-185.
    • (2015) Chem. Biol. , vol.22 , pp. 175-185
    • Tam, J.1
  • 4
    • 84942543705 scopus 로고    scopus 로고
    • A small-molecule antivirulence agent for treating Clostridium difficile infection
    • Bender K.O., et al. A small-molecule antivirulence agent for treating Clostridium difficile infection. Sci. Transl. Med. 2015, 7:306ra148.
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    • Bender, K.O.1
  • 5
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    • Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
    • Azad G.K., Tomar R.S. Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways. Mol. Biol. Rep. 2014, 41:4865-4879.
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    • Azad, G.K.1    Tomar, R.S.2
  • 6
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    • Cytotoxicity of Clostridium difficile toxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol
    • Li S., et al. Cytotoxicity of Clostridium difficile toxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol. Pathog. Dis. 2013, 67:11-18.
    • (2013) Pathog. Dis. , vol.67 , pp. 11-18
    • Li, S.1
  • 7
    • 84872017421 scopus 로고    scopus 로고
    • Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism
    • Chumbler N.M., et al. Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism. PLoS Pathog. 2012, 8:e1003072.
    • (2012) PLoS Pathog. , vol.8 , pp. e1003072
    • Chumbler, N.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.