-
1
-
-
0024458904
-
Intermediate states in the movement of transfer RNA in the ribosome
-
Moazed, D. &Noller, H.F. Intermediate states in the movement of transfer RNA in the ribosome. Nature 342, 142-148 (1989).
-
(1989)
Nature
, vol.342
, pp. 142-148
-
-
Moazed, D.1
Noller, H.F.2
-
2
-
-
84891369006
-
Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation
-
Ramrath, D.J. et al. Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proc. Natl. Acad. Sci. USA 110, 20964-20969 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20964-20969
-
-
Ramrath, D.J.1
-
3
-
-
84907187230
-
How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation
-
Zhou, J., Lancaster, L., Donohue, J.P. &Noller, H.F. How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation. Science 345, 1188-1191 (2014).
-
(2014)
Science
, vol.345
, pp. 1188-1191
-
-
Zhou, J.1
Lancaster, L.2
Donohue, J.P.3
Noller, H.F.4
-
4
-
-
84879661481
-
Control of ribosomal subunit rotation by elongation factor G
-
Pulk, A. &Cate, J.H. Control of ribosomal subunit rotation by elongation factor G. Science 340, 1235970 (2013).
-
(2013)
Science
, vol.340
, pp. 1235970
-
-
Pulk, A.1
Cate, J.H.2
-
5
-
-
84879663355
-
Elongation factor G bound to the ribosome in an intermediate state of translocation
-
Tourigny, D.S., Fernández, I.S., Kelley, A.C. &Ramakrishnan, V. Elongation factor G bound to the ribosome in an intermediate state of translocation. Science 340, 1235490 (2013).
-
(2013)
Science
, vol.340
, pp. 1235490
-
-
Tourigny, D.S.1
Fernández, I.S.2
Kelley, A.C.3
Ramakrishnan, V.4
-
6
-
-
84879625362
-
Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation
-
Zhou, J., Lancaster, L., Donohue, J.P. &Noller, H.F. Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. Science 340, 1236086 (2013).
-
(2013)
Science
, vol.340
, pp. 1236086
-
-
Zhou, J.1
Lancaster, L.2
Donohue, J.P.3
Noller, H.F.4
-
7
-
-
78649873931
-
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
-
Ratje, A.H. et al. Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468, 713-716 (2010).
-
(2010)
Nature
, vol.468
, pp. 713-716
-
-
Ratje, A.H.1
-
8
-
-
79955494464
-
Single-molecule fluorescence measurements of ribosomal translocation dynamics
-
Chen, C. et al. Single-molecule fluorescence measurements of ribosomal translocation dynamics. Mol. Cell 42, 367-377 (2011).
-
(2011)
Mol. Cell
, vol.42
, pp. 367-377
-
-
Chen, C.1
-
9
-
-
84931275242
-
Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome
-
Adio, S. et al. Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nat. Commun. 6, 7442 (2015).
-
(2015)
Nat. Commun
, vol.6
, pp. 7442
-
-
Adio, S.1
-
10
-
-
27644491082
-
Structures of the bacterial ribosome at 3.5 A resolution
-
Schuwirth, B.S. et al. Structures of the bacterial ribosome at 3.5 A resolution. Science 310, 827-834 (2005).
-
(2005)
Science
, vol.310
, pp. 827-834
-
-
Schuwirth, B.S.1
-
11
-
-
69249112231
-
Structures of the ribosome in intermediate states of ratcheting
-
Zhang, W., Dunkle, J.A. &Cate, J.H. Structures of the ribosome in intermediate states of ratcheting. Science 325, 1014-1017 (2009).
-
(2009)
Science
, vol.325
, pp. 1014-1017
-
-
Zhang, W.1
Dunkle, J.A.2
Cate, J.H.3
-
12
-
-
54049116765
-
Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome
-
Agirrezabala, X. et al. Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome. Mol. Cell 32, 190-197 (2008).
-
(2008)
Mol. Cell
, vol.32
, pp. 190-197
-
-
Agirrezabala, X.1
-
13
-
-
0034691576
-
A ratchet-like inter-subunit reorganization of the ribosome during translocation
-
Frank, J. &Agrawal, R.K. A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature 406, 318-322 (2000).
-
(2000)
Nature
, vol.406
, pp. 318-322
-
-
Frank, J.1
Agrawal, R.K.2
-
14
-
-
55949134736
-
Structure of ratcheted ribosomes with tRNAs in hybrid states
-
Julián, P. et al. Structure of ratcheted ribosomes with tRNAs in hybrid states. Proc. Natl. Acad. Sci. USA 105, 16924-16927 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16924-16927
-
-
Julián, P.1
-
15
-
-
84899892794
-
GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits
-
Holtkamp, W. et al. GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits. EMBO J. 33, 1073-1085 (2014).
-
(2014)
EMBO J
, vol.33
, pp. 1073-1085
-
-
Holtkamp, W.1
-
16
-
-
0038433302
-
An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation
-
Savelsbergh, A. et al. An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation. Mol. Cell 11, 1517-1523 (2003).
-
(2003)
Mol. Cell
, vol.11
, pp. 1517-1523
-
-
Savelsbergh, A.1
-
17
-
-
29244445859
-
Control of phosphate release from elongation factor G by ribosomal protein L7/12
-
Savelsbergh, A., Mohr, D., Kothe, U., Wintermeyer, W. &Rodnina, M.V. Control of phosphate release from elongation factor G by ribosomal protein L7/12. EMBO J. 24, 4316-4323 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 4316-4323
-
-
Savelsbergh, A.1
Mohr, D.2
Kothe, U.3
Wintermeyer, W.4
Rodnina, M.V.5
-
18
-
-
84879631445
-
Dual use of GTP hydrolysis by elongation factor G on the ribosome
-
Cunha, C.E. et al. Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 1, e24315 (2013).
-
(2013)
Translation
, vol.1
, pp. e24315
-
-
Cunha, C.E.1
-
19
-
-
0031028688
-
Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome
-
Rodnina, M.V., Savelsbergh, A., Katunin, V.I. &Wintermeyer, W. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 385, 37-41 (1997).
-
(1997)
Nature
, vol.385
, pp. 37-41
-
-
Rodnina, M.V.1
Savelsbergh, A.2
Katunin, V.I.3
Wintermeyer, W.4
-
20
-
-
6344252614
-
Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation
-
Peske, F., Savelsbergh, A., Katunin, V.I., Rodnina, M.V. &Wintermeyer, W. Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation. J. Mol. Biol. 343, 1183-1194 (2004).
-
(2004)
J. Mol. Biol
, vol.343
, pp. 1183-1194
-
-
Peske, F.1
Savelsbergh, A.2
Katunin, V.I.3
Rodnina, M.V.4
Wintermeyer, W.5
-
21
-
-
0017730231
-
The inhibition of ribosomal translocation by viomycin
-
Modolell, J. &Vázquez, D. The inhibition of ribosomal translocation by viomycin. Eur. J. Biochem. 81, 491-497 (1977).
-
(1977)
Eur. J. Biochem
, vol.81
, pp. 491-497
-
-
Modolell, J.1
Vázquez, D.2
-
22
-
-
84922261128
-
A monovalent cation acts as structural and catalytic cofactor in translational GTPases
-
Kuhle, B. &Ficner, R. A monovalent cation acts as structural and catalytic cofactor in translational GTPases. EMBO J. 33, 2547-2563 (2014).
-
(2014)
EMBO J
, vol.33
, pp. 2547-2563
-
-
Kuhle, B.1
Ficner, R.2
-
23
-
-
84890168470
-
Energy barriers and driving forces in tRNA translocation through the ribosome
-
Bock, L.V. et al. Energy barriers and driving forces in tRNA translocation through the ribosome. Nat. Struct. Mol. Biol. 20, 1390-1396 (2013).
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 1390-1396
-
-
Bock, L.V.1
-
24
-
-
77954650144
-
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy
-
Fischer, N., Konevega, A.L., Wintermeyer, W., Rodnina, M.V. &Stark, H. Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy. Nature 466, 329-333 (2010).
-
(2010)
Nature
, vol.466
, pp. 329-333
-
-
Fischer, N.1
Konevega, A.L.2
Wintermeyer, W.3
Rodnina, M.V.4
Stark, H.5
-
25
-
-
34250220008
-
Observation of intersubunit movement of the ribosome in solution using FRET
-
Ermolenko, D.N. et al. Observation of intersubunit movement of the ribosome in solution using FRET. J. Mol. Biol. 370, 530-540 (2007).
-
(2007)
J. Mol. Biol
, vol.370
, pp. 530-540
-
-
Ermolenko, D.N.1
-
26
-
-
79953777970
-
mRNA translocation occurs during the second step of ribosomal intersubunit rotation
-
Ermolenko, D.N. &Noller, H.F. mRNA translocation occurs during the second step of ribosomal intersubunit rotation. Nat. Struct. Mol. Biol. 18, 457-462 (2011).
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 457-462
-
-
Ermolenko, D.N.1
Noller, H.F.2
-
27
-
-
34249887127
-
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
-
Ermolenko, D.N. et al. The antibiotic viomycin traps the ribosome in an intermediate state of translocation. Nat. Struct. Mol. Biol. 14, 493-497 (2007).
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 493-497
-
-
Ermolenko, D.N.1
-
28
-
-
84870928681
-
Rotation of the head of the 30S ribosomal subunit during mRNA translocation
-
Guo, Z. &Noller, H.F. Rotation of the head of the 30S ribosomal subunit during mRNA translocation. Proc. Natl. Acad. Sci. USA 109, 20391-20394 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 20391-20394
-
-
Guo, Z.1
Noller, H.F.2
-
29
-
-
84878909556
-
Coordinated conformational and compositional dynamics drive ribosome translocation
-
Chen, J., Petrov, A., Tsai, A., O'Leary, S.E. &Puglisi, J.D. Coordinated conformational and compositional dynamics drive ribosome translocation. Nat. Struct. Mol. Biol. 20, 718-727 (2013).
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 718-727
-
-
Chen, J.1
Petrov, A.2
Tsai, A.3
O'Leary, S.E.4
Puglisi, J.D.5
-
30
-
-
84903197929
-
Programmed-1 frameshifting by kinetic partitioning during impeded translocation
-
Caliskan, N., Katunin, V.I., Belardinelli, R., Peske, F. &Rodnina, M.V. Programmed-1 frameshifting by kinetic partitioning during impeded translocation. Cell 157, 1619-1631 (2014).
-
(2014)
Cell
, vol.157
, pp. 1619-1631
-
-
Caliskan, N.1
Katunin, V.I.2
Belardinelli, R.3
Peske, F.4
Rodnina, M.V.5
-
31
-
-
71549171706
-
Fitting enzyme kinetic data with KinTek Global Kinetic Explorer
-
Johnson, K.A. Fitting enzyme kinetic data with KinTek Global Kinetic Explorer. Methods Enzymol. 467, 601-626 (2009).
-
(2009)
Methods Enzymol
, vol.467
, pp. 601-626
-
-
Johnson, K.A.1
-
32
-
-
0037159243
-
Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome
-
Katunin, V.I., Savelsbergh, A., Rodnina, M.V. &Wintermeyer, W. Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome. Biochemistry 41, 12806-12812 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 12806-12812
-
-
Katunin, V.I.1
Savelsbergh, A.2
Rodnina, M.V.3
Wintermeyer, W.4
-
33
-
-
33847024820
-
Kinetically competent intermediates in the translocation step of protein synthesis
-
Pan, D., Kirillov, S.V. &Cooperman, B.S. Kinetically competent intermediates in the translocation step of protein synthesis. Mol. Cell 25, 519-529 (2007).
-
(2007)
Mol. Cell
, vol.25
, pp. 519-529
-
-
Pan, D.1
Kirillov, S.V.2
Cooperman, B.S.3
-
34
-
-
44449125068
-
Spontaneous intersubunit rotation in single ribosomes
-
Cornish, P.V., Ermolenko, D.N., Noller, H.F. &Ha, T. Spontaneous intersubunit rotation in single ribosomes. Mol. Cell 30, 578-588 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 578-588
-
-
Cornish, P.V.1
Ermolenko, D.N.2
Noller, H.F.3
Ha, T.4
-
35
-
-
78649830457
-
Correlated conformational events in EF-G and the ribosome regulate translocation
-
Munro, J.B., Wasserman, M.R., Altman, R.B., Wang, L. &Blanchard, S.C. Correlated conformational events in EF-G and the ribosome regulate translocation. Nat. Struct. Mol. Biol. 17, 1470-1477 (2010).
-
(2010)
Nat. Struct. Mol. Biol
, vol.17
, pp. 1470-1477
-
-
Munro, J.B.1
Wasserman, M.R.2
Altman, R.B.3
Wang, L.4
Blanchard, S.C.5
-
36
-
-
0023018093
-
Pre-steady-state kinetics of ribosomal translocation
-
Robertson, J.M., Paulsen, H. &Wintermeyer, W. Pre-steady-state kinetics of ribosomal translocation. J. Mol. Biol. 192, 351-360 (1986).
-
(1986)
J. Mol. Biol
, vol.192
, pp. 351-360
-
-
Robertson, J.M.1
Paulsen, H.2
Wintermeyer, W.3
-
37
-
-
84891354515
-
Structure of the ribosome with elongation factor G trapped in the pretranslocation state
-
Brilot, A.F., Korostelev, A.A., Ermolenko, D.N. &Grigorieff, N. Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc. Natl. Acad. Sci. USA 110, 20994-20999 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20994-20999
-
-
Brilot, A.F.1
Korostelev, A.A.2
Ermolenko, D.N.3
Grigorieff, N.4
-
38
-
-
84927635725
-
Determinants of the rate of mRNA translocation in bacterial protein synthesis
-
Borg, A. &Ehrenberg, M. Determinants of the rate of mRNA translocation in bacterial protein synthesis. J. Mol. Biol. 427, 1835-1847 (2015).
-
(2015)
J. Mol. Biol
, vol.427
, pp. 1835-1847
-
-
Borg, A.1
Ehrenberg, M.2
-
39
-
-
0023645232
-
Mechanism of ribosomal translocation tRNA binds transiently to an exit site before leaving the ribosome during translocation
-
Robertson, J.M. &Wintermeyer, W. Mechanism of ribosomal translocation. tRNA binds transiently to an exit site before leaving the ribosome during translocation. J. Mol. Biol. 196, 525-540 (1987).
-
(1987)
J. Mol. Biol
, vol.196
, pp. 525-540
-
-
Robertson, J.M.1
Wintermeyer, W.2
-
40
-
-
84907298204
-
Molecular mechanics of 30S subunit head rotation
-
Mohan, S., Donohue, J.P. &Noller, H.F. Molecular mechanics of 30S subunit head rotation. Proc. Natl. Acad. Sci. USA 111, 13325-13330 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 13325-13330
-
-
Mohan, S.1
Donohue, J.P.2
Noller, H.F.3
-
41
-
-
0028941626
-
GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs
-
Rodnina, M.V. &Wintermeyer, W. GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs. Proc. Natl. Acad. Sci. USA 92, 1945-1949 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1945-1949
-
-
Rodnina, M.V.1
Wintermeyer, W.2
-
42
-
-
23644434688
-
Measurement of internal movements within the 30 S ribosomal subunit using Förster resonance energy transfer
-
Hickerson, R., Majumdar, Z.K., Baucom, A., Clegg, R.M. &Noller, H.F. Measurement of internal movements within the 30 S ribosomal subunit using Förster resonance energy transfer. J. Mol. Biol. 354, 459-472 (2005).
-
(2005)
J. Mol. Biol
, vol.354
, pp. 459-472
-
-
Hickerson, R.1
Majumdar, Z.K.2
Baucom, A.3
Clegg, R.M.4
Noller, H.F.5
-
43
-
-
0034646564
-
The 23 S rRNA environment of ribosomal protein L9 in the 50 S ribosomal subunit
-
Lieberman, K.R. et al. The 23 S rRNA environment of ribosomal protein L9 in the 50 S ribosomal subunit. J. Mol. Biol. 297, 1129-1143 (2000).
-
(2000)
J. Mol. Biol
, vol.297
, pp. 1129-1143
-
-
Lieberman, K.R.1
-
44
-
-
23644433196
-
Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: Quantitative spectroscopic methods
-
Majumdar, Z.K., Hickerson, R., Noller, H.F. &Clegg, R.M. Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: quantitative spectroscopic methods. J. Mol. Biol. 351, 1123-1145 (2005).
-
(2005)
J. Mol. Biol
, vol.351
, pp. 1123-1145
-
-
Majumdar, Z.K.1
Hickerson, R.2
Noller, H.F.3
Clegg, R.M.4
-
45
-
-
60549112465
-
FitSpace explorer: An algorithm to evaluate multidimensional parameter space in fitting kinetic data
-
Johnson, K.A., Simpson, Z.B. &Blom, T. FitSpace explorer: an algorithm to evaluate multidimensional parameter space in fitting kinetic data. Anal. Biochem. 387, 30-41 (2009).
-
(2009)
Anal. Biochem
, vol.387
, pp. 30-41
-
-
Johnson, K.A.1
Simpson, Z.B.2
Blom, T.3
-
46
-
-
60549105802
-
Global kinetic explorer: A new computer program for dynamic simulation and fitting of kinetic data
-
Johnson, K.A., Simpson, Z.B. &Blom, T. Global kinetic explorer: a new computer program for dynamic simulation and fitting of kinetic data. Anal. Biochem. 387, 20-29 (2009).
-
(2009)
Anal. Biochem
, vol.387
, pp. 20-29
-
-
Johnson, K.A.1
Simpson, Z.B.2
Blom, T.3
|