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Volumn 54, Issue 3, 2016, Pages 217-227
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Relative bioavailability, food effect, and safety of the single-dose pharmacokinetics of omecamtiv mecarbil following administration of different modified-release formulations in healthy subjects
a
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Author keywords
Bioavailability; Food effect; Modified release; Omecamtiv mecarbil; Pharmacokinetics
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Indexed keywords
CREATINE KINASE;
DRUG METABOLITE;
OMECAMTIV MECARBIL;
UREA;
ADULT;
AREA UNDER THE CURVE;
ARTICLE;
CONTACT DERMATITIS;
CONTROLLED STUDY;
CREATINE KINASE BLOOD LEVEL;
CROSSOVER PROCEDURE;
DIET RESTRICTION;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG BLOOD LEVEL;
DRUG CAPSULE;
DRUG DOSAGE FORM COMPARISON;
DRUG FORMULATION;
DRUG RELEASE;
DRUG SAFETY;
DRUG TOLERABILITY;
DRUG WITHDRAWAL;
FEMALE;
FOOD;
FOOD DRUG INTERACTION;
HEADACHE;
HEART VENTRICLE EXTRASYSTOLE;
HUMAN;
HUMAN EXPERIMENT;
IMMEDIATE RELEASE MATRIX FORMULATION;
MALE;
MATRIX TABLET;
MAXIMUM PLASMA CONCENTRATION;
MODIFIED RELEASE FORMULATION;
MULTIPARTICULATE CAPSULE;
MUSCLE INJURY;
NORMAL HUMAN;
OPEN STUDY;
PATIENT COMPLIANCE;
PHASE 1 CLINICAL TRIAL;
RANDOMIZED CONTROLLED TRIAL;
SIDE EFFECT;
SINGLE DRUG DOSE;
SWELLABLE CORE TABLET;
TABLET FORMULATION;
TIME TO MAXIMUM PLASMA CONCENTRATION;
UPPER RESPIRATORY TRACT INFECTION;
URINARY TRACT INFECTION;
VOMITING;
ADOLESCENT;
ANALOGS AND DERIVATIVES;
BIOAVAILABILITY;
CLINICAL TRIAL;
MEDICINAL CHEMISTRY;
MIDDLE AGED;
ADOLESCENT;
ADULT;
AREA UNDER CURVE;
BIOLOGICAL AVAILABILITY;
CHEMISTRY, PHARMACEUTICAL;
CROSS-OVER STUDIES;
FEMALE;
FOOD-DRUG INTERACTIONS;
HUMANS;
MALE;
MIDDLE AGED;
UREA;
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EID: 84961245615
PISSN: 09461965
EISSN: None
Source Type: Journal
DOI: 10.5414/CP202458 Document Type: Article |
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Times cited : (27)
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References (9)
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