Ketamine-Induced Apoptosis in Normal Human Urothelial Cells: A Direct, N-Methyl-D-Aspartate Receptor-Independent Pathway Characterized by Mitochondrial Stress

American Journal of Pathology

Volumn 186, Issue 5, 2016, Pages 1267-1277

  Baker, Simon C ^a   Shabir, Saqib ^a   Georgopoulos, Nikolaos T ^b   Southgate, Jennifer ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; INOSITOL TRISPHOSPHATE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PURINERGIC P2Y RECEPTOR; AMINO ACID RECEPTOR BLOCKING AGENT; ANALGESIC AGENT;

APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL STRESS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTALGIA; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MITOCHONDRIAL STRESS; NORMAL HUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UROTHELIUM; ANTAGONISTS AND INHIBITORS; BLADDER; CALCIUM SIGNALING; CELL CULTURE; CHEMICALLY INDUCED; CYSTITIS; DOSE RESPONSE; DRUG EFFECTS; MITOCHONDRION; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

ANALGESICS; APOPTOSIS; CALCIUM SIGNALING; CELLS, CULTURED; CYSTITIS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; KETAMINE; MITOCHONDRIA; OXYGEN CONSUMPTION; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; URINARY BLADDER; UROTHELIUM;

EID: 84961219147     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.12.014     Document Type: Article

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