The Relationship Between 24-Hour Symptoms and COPD Exacerbations and Healthcare Resource Use: Results from an Observational Study (ASSESS)

COPD: Journal of Chronic Obstructive Pulmonary Disease

Volumn 13, Issue 5, 2016, Pages 561-568

  Miravitlles, Marc ^a   Worth, Heinrich ^b   Soler Cataluña, Juan José ^c   Price, David ^d   De Benedetto, Fernando ^e   Roche, Nicolas ^f   Godtfredsen, Nina S ^g   van der Molen, Thys ^h   Löfdahl, Claes Göran ⁱ   Padullés, Laura ^j   Ribera, Anna ^k  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b Praxis Drs Bily Kellermann   (Germany)

^c HOSPITAL ARNAU DE VILANOVA   (Spain)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e UNIVERSITY OF CHIETI   (Italy)

^f Paris Descartes University ^*  (France)

^g HVIDOVRE HOSPITAL   (Denmark)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ LUND UNIVERSITY HOSPITAL   (Sweden)

^j Almirall SA ^*  (Spain)

^k ASTRAZENECA   (United Kingdom)

more..

Author keywords

Cohort; exacerbation risk; morning symptoms; nighttime symptoms; prospective; retrospective

Indexed keywords

AGED; ANXIETY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DEPRESSION; DISEASE ASSOCIATION; DISEASE EXACERBATION; DYSPNEA; FEMALE; FOLLOW UP; FREQUENCY; HEALTH CARE SYSTEM; HEALTH CARE UTILIZATION; HEALTH STATUS; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; NIGHT; OBSERVATIONAL STUDY; PATIENT INFORMATION; PHYSICAL ACTIVITY; PREDICTIVE VALUE; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; QUESTIONNAIRE; SEX RATIO; SLEEP QUALITY; SMOKING; SYMPTOM; TIME; AMBULATORY CARE; CLINICAL TRIAL; COMPLICATION; FORCED EXPIRATORY VOLUME; FORECASTING; HEALTH CARE PLANNING; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PRIMARY HEALTH CARE; RECURRENT DISEASE; SYMPTOM ASSESSMENT; TIME FACTOR; UTILIZATION;

AGED; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; FORCED EXPIRATORY VOLUME; FORECASTING; HEALTH RESOURCES; HUMANS; MALE; MIDDLE AGED; OFFICE VISITS; PRIMARY HEALTH CARE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SURVEYS AND QUESTIONNAIRES; SYMPTOM ASSESSMENT; SYMPTOM FLARE UP; TIME FACTORS;

EID: 84961197661     PISSN: 15412555     EISSN: 15412563     Source Type: Journal    
DOI: 10.3109/15412555.2016.1150447     Document Type: Article

References (34)

1. T.van der Molen, M.Miravitlles, J.W.Kocks. COPD management:role of symptom assessment in routine clinical practice. Int J Chron Obstruct Pulmon Dis 2013; 8:461–471.
2. M.R.Partridge, N.Karlsson, I.R.Small. Patient insight into the impact of chronic obstructive pulmonary disease in the morning:an internet survey. Curr Med Res Opin 2009; 25:2043–2048.
3. M.J.Espinosa de los Monteros, C.Pena, E.J.Soto Hurtado, J.Jareno, M.Miravitlles. Variability of respiratory symptoms in severe COPD. Arch Bronconeumol 2012; 48:3–7.
4. A.Agusti, J.Hedner, J.M.Marin, B.FBarbé, M.Cazzola, S.Rennard. Night-time symptoms:A forgotten dimension of COPD. Eur Respir Rev 2011; 20:183–194.
5. D.Price, M.Small, G.Milligan, V.Higgins, E.Garcia Gil, J.Estruch. Impact of night-time symptoms in COPD:a real-world study in five European countries. Int J Chron Obstruct Pulmon Dis 2013; 8:595–603.
6. N.Roche, M.Small, S.Broomfield, V.Higgins, R.Pollard. Real world COPD:Association of morning symptoms with clinical and patient reported outcomes. COPD 2013; 10:679–686.
7. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease [Internet]. [updated 2014; cited 2015 Apr 16]. Available from:http://www.goldcopd.org/uploads/users/files/GOLD_Report2014_Feb07.pdf.
8. A.Anzueto, I.Leimer, S.Kesten. Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes. Int J Chron Obstruct Pulmon Dis 2009; 4:245–251.
9. M.Miravitlles, M.Ferrer, A.Pont, R.Zalacain, J.L.Alvarez-Sala, F.Masa, et al. Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease:a 2 year follow up study. Thorax 2004; 59:387–395.
10. D.M.Halpin, M.Decramer, B.Celli, S.Kesten, D.Liu, D.P.Tashkin. Exacerbation frequency and course of COPD. Int J Chron Obstruct Pulmon Dis 2012; 7:653–661.
11. J.J.Soler-Cataluna, M.A.Martinez-Garcia, S.P.Roman, E.Salcedo, M.Navarro, R.Ochando. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax 2005; 60:925–931.
12. E.L.Toy, K.F.Gallagher, E.L.Stanley, A.R.Swensen, M.S.Duh. The economic impact of exacerbations of chronic obstructive pulmonary disease and exacerbation definition:A review. COPD 2010; 7:214–228.
13. M.Miravitlles, C.Garcia-Polo, A.Domenech, G.Villegas, F.Conget, C.de la Roza. Clinical outcomes and cost analysis of exacerbations in chronic obstructive pulmonary disease. Lung 2013; 191:523–530.
14. J.R.Hurst, J.Vestbo, A.Anzueto, N.Locantore, H.Müllerova, R.Tal-Singer et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 2010; 363:1128–1138.
15. M.L.Moy, M.Teylan, N.A.Weston, D.R.Gagnon, E.Garshick. Daily step count predicts acute exacerbations in a US cohort with COPD. PLoS One 2013; 8:e60400.
16. K.M.Beeh, T.Glaab, S.Stowasser, H.Schmidt, L.M.Fabbri, K.F.Rabe et al. Characterisation of exacerbation risk and exacerbator phenotypes in the POET-COPD trial. Respir Res 2013; 14:116.
17. P.R.Burgel, P.Nesme-Meyer, P.Chanez, D.Caillaud, C.PCarré, T.Perez et al. Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects. Chest 2009; 135:975–982.
18. D.E.Niewoehner, Y.Lokhnygina, K.Rice, W.G.Kuschner, A.Sharafkhaneh, G.A.Sarosi, et al. Risk indexes for exacerbations and hospitalizations due to COPD. Chest 2007; 131:20–28.
19. J.K.Quint, R.Baghai-Ravary, G.C.Donaldson, J.A.Wedzicha. Relationship between depression and exacerbations in COPD. Eur Respir J 2008; 32:53–60.
20. M.Miravitlles, H.Worth, J.J.Soler Cataluna, D.Price, F.De Benedetto, N.Roche et al. Observational study to characterise 24-hour COPD symptoms and their relationship with patient-reported outcomes:results from the ASSESS study. Respir Res 2014; 15:122.
21. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease [Internet]. [updated 2010; cited 2014 Oct 20]. Available from:http://www.goldcopd.org/Guidelines/guideline-2010-gold-report.html.
22. J.C.Bestall, E.A.Paul, R.Garrod, R.Garnham, P.W.Jones, J.A.Wedzicha. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax 1999; 54:581–586.
23. P.W.Jones, G.Harding, P.Berry, I.Wiklund, W.H.Chen, N.Kline Leidy. Development and first validation of the COPD Assessment Test. Eur Respir J 2009; 34:648–654.
24. A.S.Zigmond, R.P.Snaith. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67:361–370.
25. R.F.Pokrzywinski, D.M.Meads, S.P.McKenna, G.A.Glendenning, D.A.Revicki. Development and psychometric assessment of the COPD and Asthma Sleep Impact Scale (CASIS). Health Qual Life Outcomes 2009; 7:98.
26. M.Miravitlles, M.Iriberri, M.Barrueco, M.Lleonart, E.Villarrubia, J.Galera. Usefulness of the LCOPD, CAFS and CASIS scales in understanding the impact of COPD on patients. Respiration 2013; 86:190–200.
27. B.Celli, J.Vestbo, C.R.Jenkins, P.W.Jones, G.T.Ferguson, P.M.Calverley et al. Sex differences in mortality and clinical expressions of patients with chronic obstructive pulmonary disease. The TORCH experience. Am J Respir Crit Care Med 2011; 183:317–322.
28. K.Naberan, A.Azpeitia, J.Cantoni, M.Miravitlles. Impairment of quality of life in women with chronic obstructive pulmonary disease. Respir Med 2012; 106:367–373.
29. M.Kerkhof, D.Freeman, R.Jones, A.Chisholm, D.B.Price. Predicting frequent COPD exacerbations using primary care data. Int J Chron Obstruct Pulmon Dis 2015; 10:2439–2450.
30. F.Di Marco, M.Verga, M.Reggente, C.F.Maria, P.Santus, F.Blasi et al. Anxiety and depression in COPD patients:The roles of gender and disease severity. Respir Med 2006; 100:1767–1774.
31. R.Kessler, M.R.Partridge, M.Miravitlles, M.Cazzola, C.Vogelmeier, D.Leynaud et al. Symptom variability in patients with severe COPD:A pan-European cross-sectional study. Eur Respir J 2011; 37:264–272.
32. D.Price, D.West, G.Brusselle, K.Gruffydd-Jones, R.Jones, M.Miravitlles et al. Management of COPD in the UK primary-care setting:An analysis of real-life prescribing patterns. Int J Chron Obstruct Pulmon Dis 2014; 9:889–904.
33. M.Mocarski, E.Zaiser, D.Trundell, B.J.Make, A.Hareendran. Evaluation of the psychometric properties of the Nighttime Symptoms of COPD Instrument. Int J Chron Obstruct Pulmon Dis 2015; 10:475–487.
34. M.Mocarski, A.Hareendran, M.H.Jen, E.Zaiser, B.J.Make. Evaluation of the psychometric properties of the early morning symptoms of COPD instrument (EMSCI). Value Health 2014; 17 (3):A179.