Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels

Journal of Allergy and Clinical Immunology

Volumn 138, Issue 1, 2016, Pages 299-303

  Shoda, Tetsuo ^a,b   Matsuda, Akio ^a   Arai, Katsuhiro ^b   Shimizu, Hirotaka ^b   Morita, Hideaki ^a   Orihara, Kanami ^a,c   Okada, Naoko ^a   Narita, Masami ^b   Ohya, Yukihiro ^b   Saito, Hirohisa ^a   Matsumoto, Kenji ^a   Nomura, Ichiro ^a,b  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CUTANEOUS T CELL ATTRACTING CHEMOKINE; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; EOTAXIN; GAMMA INTERFERON; GRANULOCYTE CHEMOTACTIC PROTEIN 2; INTERLEUKIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 4; SECONDARY LYMPHOID TISSUE CHEMOKINE; THYMIC STROMAL LYMPHOPOIETIN; CCL21 PROTEIN, HUMAN; CCL27 PROTEIN, HUMAN; CCL7 PROTEIN, HUMAN; CYTOKINE; IL33 PROTEIN, HUMAN; MONOCYTE CHEMOTACTIC PROTEIN 3;

ARTICLE; ATOPIC DERMATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; EOSINOPHILIA; EOSINOPHILIC GASTROENTERITIS; FOOD ALLERGY; GASTROINTESTINAL ENDOSCOPY; GASTROINTESTINAL MUCOSA; GENE EXPRESSION; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGMOID; UPREGULATION; WEIGHT REDUCTION; BLOOD; CASE CONTROL STUDY; ENTERITIS; EOSINOPHIL; FEMALE; GASTRITIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFANT; MALE; PATHOLOGY;

CASE-CONTROL STUDIES; CHEMOKINE CCL21; CHEMOKINE CCL27; CHEMOKINE CCL7; CYTOKINES; ENTERITIS; EOSINOPHILIA; EOSINOPHILS; FEMALE; GASTRITIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFANT; INTERLEUKIN-33; MALE;

EID: 84961180535     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.11.042     Document Type: Article

References (9)

1. 1 Rothenberg, M.E., Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol 113 (2004), 11–28.
2. 2 Sherrill, J.D., Rothenberg, M.E., Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. J Allergy Clin Immunol 128 (2011), 23–32.
3. 3 Kinoshita, Y., Furuta, K., Ishimura, N., Ishihara, S., Elevated plasma cytokines in Japanese patients with eosinophilic esophagitis and gastroenteritis. Digestion 86 (2012), 238–243.
4. 4 DeBrosse, C.W., Case, J.W., Putnam, P.E., Collins, M.H., Rothenberg, M.E., Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatr Dev Pathol 9 (2006), 210–218.
5. 5 Divekar, R., Kita, H., Recent advances in epithelium-derived cytokines (IL-33, IL-25, and thymic stromal lymphopoietin) and allergic inflammation. Curr Opin Allergy Clin Immunol 15 (2015), 98–103.
6. 6 Pastorelli, L., Garg, R.R., Hoang, S.B., Spina, L., Mattioli, B., Scarpa, M., et al. Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci U S A 107 (2010), 8017–8022.
7. 7 Tamagawa-Mineoka, R., Okuzawa, Y., Masuda, K., Katoh, N., Increased serum levels of interleukin 33 in patients with atopic dermatitis. J Am Acad Dermatol 70 (2014), 882–888.
8. 8 Nomura, I., Morita, H., Hosokawa, S., Hoshina, H., Fukuie, T., Watanabe, M., et al. Four distinct subtypes of non-IgE-mediated gastrointestinal food allergies in neonates and infants, distinguished by their initial symptoms. J Allergy Clin Immunol 127 (2011), 685–688.
9. 9 Nowak-Wegrzyn, A., Katz, Y., Mehr, S.S., Koletzko, S., Non-IgE-mediated gastrointestinal food allergy. J Allergy Clin Immunol 135 (2015), 1114–1124.