The effect of protocatechuic acid on blood pressure and oxidative stress in glucocorticoid-induced hypertension in rat

Iranian Journal of Pharmaceutical Research

Volumn 15, Issue , 2016, Pages 83-91

  Safaeian, Leila ^a   Hajhashemi, Valiollah ^a   Javanmard, Shaghayegh Haghjoo ^b   Naderi, Hamed Sanaye ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antioxidants; Dexamethasone; Hypertension; Protocatechuic acid

Indexed keywords

ASCORBIC ACID; CAPTOPRIL; DEXAMETHASONE; HYDROGEN PEROXIDE; PROTOCATECHUIC ACID; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; HYPERTENSION; MALE; NONHUMAN; OXIDATIVE STRESS; PREVENTION STUDY; RAT; SYSTOLIC BLOOD PRESSURE; THYMUS; WEIGHT REDUCTION;

EID: 84961114568     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Feng XL, Pang M and Beard J. Health system strengthening and hypertension awareness, treatment and control: data from the China Health and Retirement Longitudinal Study. Bull. World Health Organ. (2014) 92: 29-41.
2. Wang S, Xu L, Jonas JB, Wong TY, Cui T, Li Y, Wang YX, You QS, Yang H and Sun C. Major eye diseases and risk factors associated with systemic hypertension in an adult Chinese population: the Beijing Eye Study. Ophthalmology (2009) 116: 2373-80.
3. Maki KC, Rains TM, Schild AL, Dicklin MR, Park KM, Lawless AL and Kelley KM. Effects of low-fat dairy intake on blood pressure, endothelial function, and lipoprotein lipids in subjects with prehypertension or stage 1 hypertension. Vasc. Health Risk Manag. (2013) 9: 369-79.
4. Meshram II, Arlappa N, Balkrishna N, Rao KM, Laxmaiah A and Brahmam GN. Prevalence of hypertension, its correlates and awareness among adult tribal population of Kerala state, India. J. Postgrad. Med. (2012) 58: 255-61.
5. Safaeian L, Ghasemi-Dehkordi N, Javanmard SH and Namvar H. Antihypertensive and antioxidant effects of a hydroalcoholic extract obtained from aerial parts of Otostegia persica (Burm.) Boiss. Res. Pharm. Sci. (2015) 10: 192-9.
6. Güder A and Korkmaz H. Evaluation of in-vitro antioxidant properties of hydroalcoholic solution extracts Urtica dioica L., Malva neglecta Wallr. and their mixture. Iran. J. Pharm. Res. (2012) 11: 913-23.
7. Safaeian L and Zabolian H. Antioxidant effects of bovine lactoferrin on dexamethasone-induced hypertension in rat. ISRN Pharmacol. (2014) 2014: 943523.
8. Zhang Y, Croft KD, Mori TA, Schyvens CG, McKenzie KU and Whitworth JA. The antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat. Am. J. Hypertens. (2004) 17: 260-265.
9. Houston MC. The role of nutrition, nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension. Altern. Ther. Health Med. (2013) 1: 32-49.
10. An LJ, Guan S, Shi GF, Bao YM, Duan YL and Jiang B. Antihyperglycemic effect of protocatechuic acid on streptozotocin-diabetic rats. J. Basic Clin. Physiol. Pharmacol. (2010) 21: 79-91.
11. Masella R, Santangelo C, Darchivio M, Li Volti G, Giovannini C and Galvano F. Protocatechuic acid and human disease prevention: biological activities and molecular mechanisms. Curr. Med. Chem. (2012) 19: 2901-17.
12. Deng JS, Lee SD, Kuo WW, Fan MJ, Lin YM, Hu WS, Huang YC, Velmurugan BK, Tsai FJ, Tsai CH and Huang CY. Anti-apoptotic and pro-survival effect of protocatechuic acid on hypertensive hearts. Chem. Biol. Interact. (2014) 209: 77-84.
13. Tsai SJ and Yin MC. Anti-glycative and anti-inflammatory effects of protocatechuic acid in brain of mice treated by D-galactos. Food Chem. Toxicol. (2012) 50: 3198-205.
14. Harini R and Pugalendi KV. Antihyperglycemic effect of protocatechuic acid on streptozotocin-diabetic rats. J. Basic Clin. Physiol. Pharmacol. (2010) 21: 79-91.
15. Wang D, Wei X, Yan X, Jin T and Ling W. Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice. J. Agric. Food. Chem. (2010) 58: 12722-8.
16. Zhou-Stache J, Buettner R, Artmann G, Mittermayer C and Bosserhoff AK. Inhibition of TNF-alpha induced cell death in human umbilical vein endothelial cells and Jurkat cells by protocatechuic acid. Med. Biol. Eng. Comput. (2002) 40: 698-703.
17. Zhang Y, Wu JH, Vickers JJ, Ong SL, Temple SE, Mori TA, Croft KD and Whitworth JA. The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension. J. Hypertens. (2009) 27: 1609-16.
18. Ong SL, Vickers JJ, Zhang Y, McKenzie KU, Walsh CE and Whitworth JA. Role of xanthine oxidase in dexamethasone-induced hypertension in rats. Clin. Exp. Pharmacol. Physiol. (2007) 34: 517-9.
19. Wolf SP. Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol. (1994) 233: 182-9.
20. Benzie IF and Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP assay. Anal. Biochem. (1996) 239: 70-6.
21. Ong SL and Whitworth JA. How do glucocorticoids cause hypertension: role of nitric oxide deficiency, oxidative stress, and eicosanoids. Endocrinol. Metab. Clin. North. Am. (2011) 40: 393-407.
22. Ong SLH, Zhang Y and Whitworth JA. Mechanisms of Dexamethasone-Induced Hypertension. Curr. Hypertens. Rev. (2009) 5: 61-74.
23. Mondo CK, Yang WS, Zhang N and Huang TG. Anti-oxidant effects of atorvastatin in dexamethasone-induced hypertension in the rat. Clin. Exp. Pharmacol. Physiol. (2006) 33: 1029-34.
24. Wallace TC. Anthocyanins in cardiovascular disease. Adv. Nutr. (2011) 2: 1-7.
25. Chang WC and Hsu FL. Inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated from lonicera japonica thunb. Prostaglandins Leukot. Essent. Fatty Acids (1992) 45: 307-12.
26. Lee MJ, Chou FP, Tseng TH, Hsieh MH, Lin MC and Wang CJ. Hibiscus protocatechuic acid or esculetin can inhibit oxidative LDL induced by either copper ion or nitric oxide donor. J. Agric. Food Chem. (2002) 50: 2130-6.
27. Holland JA, O’Donnell RW, Chang MM, Johnson DK and Ziegler LM. Endothelial cell oxidant production: effect of NADPH oxidase inhibitors. Endothelium (2000) 7: 109-19.
28. Li X, Wang X, Chen D and Chen S. Antioxidant activity and mechanism of protocatechuic acid in-vitro. Funct. Foods Health Dis. (2011) 7: 232-44.
29. Virdis A, Bacca A, Colucci R, Duranti E, Fornai M, Materazzi G, Ippolito C, Bernardini N, Blandizzi C, Bernini G and Taddei S. Endothelial dysfunction in small arteries of essential hypertensive patients: role of cyclooxygenase-2 in oxidative stress generation. Hypertension (2013) 62: 337-44.
30. Akpaffiong MJ and Taylor AA. Antihypertensive and vasodilator actions of antioxidants in spontaneously hypertensive rats. Am. J. Hypertens. (1998) 11: 1450-60.
31. Vasdev S, Ford CA, Parai S, Longerich L and Gadag V. Dietary vitamin C supplementation lowers blood pressure in spontaneously hypertensive rats. Mol. Cell. Biochem. (2001) 218: 97-103.
32. Michel C and Cabanac M. Effects of dexamethasone on the body weight set point of rats. Physiol. Behav. (1999) 68: 145-50.
33. Lerario DDG, Ferreira SRG, Miranda WL and Chacra AR. Influence of dexamethasone and weight loss on the regulation of serum leptin levels in obese individuals. Braz. J. Med. Biol. Res. (2001) 34: 479-487.
34. Chmielewski V, Drupt F and Morfin R. Dexamethasone-induced apoptosis of mouse thymocytes: Prevention by native 7α-hydroxysteroids. Immunol. Cell Biol. (2000) 78: 238-246.
35. Kong F, Chen CH and Cooper MD. Reversible disruption of thymic function by steroid treatment. J. Immunol. (2002) 168: 6500-6505.